Published in J Physiol on September 01, 2000
Supramolecular assemblies and localized regulation of voltage-gated ion channels. Physiol Rev (2009) 2.53
The Physiology, Pathology, and Pharmacology of Voltage-Gated Calcium Channels and Their Future Therapeutic Potential. Pharmacol Rev (2015) 1.38
Functional expression and FRET analysis of green fluorescent proteins fused to G-protein subunits in rat sympathetic neurons. J Physiol (2001) 1.26
Regulation of Ca(V)2 calcium channels by G protein coupled receptors. Biochim Biophys Acta (2012) 1.15
Nociceptin inhibits calcium channel currents in a subpopulation of small nociceptive trigeminal ganglion neurons in mouse. J Physiol (2001) 1.10
G protein modulation of CaV2 voltage-gated calcium channels. Channels (Austin) (2010) 1.02
Prostaglandin E(2) inhibits calcium current in two sub-populations of acutely isolated mouse trigeminal sensory neurons. J Physiol (2002) 0.96
The molecular basis for T-type Ca2+ channel inhibition by G protein beta2gamma2 subunits. Proc Natl Acad Sci U S A (2006) 0.91
The familial hemiplegic migraine mutation R192Q reduces G-protein-mediated inhibition of P/Q-type (Ca(V)2.1) calcium channels expressed in human embryonic kidney cells. J Physiol (2003) 0.89
Protein kinase A activity controls the regulation of T-type CaV3.2 channels by Gbetagamma dimers. J Biol Chem (2009) 0.89
In vivo expression of G-protein beta1gamma2 dimer in adult mouse skeletal muscle alters L-type calcium current and excitation-contraction coupling. J Physiol (2010) 0.86
Custom distinctions in the interaction of G-protein beta subunits with N-type (CaV2.2) versus P/Q-type (CaV2.1) calcium channels. J Gen Physiol (2003) 0.85
Calcium channel subtypes contributing to acetylcholine release from normal, 4-aminopyridine-treated and myasthenic syndrome auto-antibodies-affected neuromuscular junctions. Br J Pharmacol (2002) 0.83
Control of neurotransmitter release: From Ca2+ to voltage dependent G-protein coupled receptors. Pflugers Arch (2010) 0.83
Scanning mutagenesis of the I-II loop of the Cav2.2 calcium channel identifies residues Arginine 376 and Valine 416 as molecular determinants of voltage dependent G protein inhibition. Mol Brain (2010) 0.82
Gβ2 and Gβ4 participate in the opioid and adrenergic receptor-mediated Ca2+ channel modulation in rat sympathetic neurons. J Physiol (2012) 0.80
Roles of N-type and Q-type Ca2+ channels in supporting hippocampal synaptic transmission. Science (1994) 4.38
Neurotransmitter inhibition of neuronal calcium currents by changes in channel voltage dependence. Nature (1989) 4.19
Voltage-dependent modulation of N-type calcium channels by G-protein beta gamma subunits. Nature (1996) 4.01
Modulation of ion-channel function by G-protein-coupled receptors. Trends Neurosci (1994) 3.80
Modulation of Ca2+ channels by G-protein beta gamma subunits. Nature (1996) 3.79
Neurotransmitters decrease the calcium conductance activated by depolarization of embryonic chick sensory neurones. J Physiol (1981) 3.61
Direct binding of G-protein betagamma complex to voltage-dependent calcium channels. Nature (1997) 2.60
Crosstalk between G proteins and protein kinase C mediated by the calcium channel alpha1 subunit. Nature (1997) 2.55
Localization and functional properties of a rat brain alpha 1A calcium channel reflect similarities to neuronal Q- and P-type channels. Proc Natl Acad Sci U S A (1994) 2.23
Direct interaction of gbetagamma with a C-terminal gbetagamma-binding domain of the Ca2+ channel alpha1 subunit is responsible for channel inhibition by G protein-coupled receptors. Proc Natl Acad Sci U S A (1997) 1.96
Splicing of alpha 1A subunit gene generates phenotypic variants of P- and Q-type calcium channels. Nat Neurosci (1999) 1.90
Determinants of the G protein-dependent opioid modulation of neuronal calcium channels. Proc Natl Acad Sci U S A (1996) 1.85
Mechanisms of modulation of voltage-dependent calcium channels by G proteins. J Physiol (1998) 1.80
Molecular cloning of the alpha-1 subunit of an omega-conotoxin-sensitive calcium channel. Proc Natl Acad Sci U S A (1992) 1.77
Multiple structural elements in voltage-dependent Ca2+ channels support their inhibition by G proteins. Neuron (1996) 1.51
Specificity of G protein beta and gamma subunit interactions. J Biol Chem (1992) 1.46
Decay of prepulse facilitation of N type calcium channels during G protein inhibition is consistent with binding of a single Gbeta subunit. Proc Natl Acad Sci U S A (1998) 1.46
Inhibition of the interaction of G protein G(o) with calcium channels by the calcium channel beta-subunit in rat neurones. J Physiol (1995) 1.36
Determinants of PKC-dependent modulation of a family of neuronal calcium channels. Neuron (1995) 1.34
Comparison of N- and P/Q-type voltage-gated calcium channel current inhibition. J Neurosci (1997) 1.34
Identification of residues in the N terminus of alpha1B critical for inhibition of the voltage-dependent calcium channel by Gbeta gamma. J Neurosci (1999) 1.29
Elementary events underlying voltage-dependent G-protein inhibition of N-type calcium channels. Biophys J (1996) 1.25
G protein modulation of N-type calcium channels is facilitated by physical interactions between syntaxin 1A and Gbetagamma. J Biol Chem (2000) 1.13
Differential ability to form the G protein betagamma complex among members of the beta and gamma subunit families. J Biol Chem (1996) 1.10
Facilitation of rabbit alpha1B calcium channels: involvement of endogenous Gbetagamma subunits. J Physiol (1998) 1.10
Identification of an integration center for cross-talk between protein kinase C and G protein modulation of N-type calcium channels. J Biol Chem (1999) 1.09
Multiple G-protein betagamma combinations produce voltage-dependent inhibition of N-type calcium channels in rat superior cervical ganglion neurons. J Neurosci (2000) 1.08
Effect of G protein heterotrimer composition on coupling of neurotransmitter receptors to N-type Ca(2+) channel modulation in sympathetic neurons. Proc Natl Acad Sci U S A (2000) 1.04
G-protein beta-subunit specificity in the fast membrane-delimited inhibition of Ca2+ channels. J Neurosci (1998) 1.04
Cloning and functional expression of novel N-type Ca(2+) channel variants. J Biol Chem (1999) 0.82
Implications of G-protein-mediated Ca2+ channel inhibition for neurotransmitter release and facilitation. J Comput Neurosci (2000) 0.81
NMDA receptors mediate calcium accumulation in myelin during chemical ischaemia. Nature (2005) 2.74
Splicing of alpha 1A subunit gene generates phenotypic variants of P- and Q-type calcium channels. Nat Neurosci (1999) 1.90
Interactions between a pore-blocking peptide and the voltage sensor of the sodium channel: an electrostatic approach to channel geometry. Neuron (1996) 1.44
Structural determinants of fast inactivation of high voltage-activated Ca(2+) channels. Trends Neurosci (2001) 1.43
The alpha 1E calcium channel exhibits permeation properties similar to low-voltage-activated calcium channels. J Neurosci (1996) 1.24
Fast inactivation of voltage-dependent calcium channels. A hinged-lid mechanism? J Biol Chem (2000) 1.23
Cysteine string protein regulates G protein modulation of N-type calcium channels. Neuron (2000) 1.23
Protease-activated receptor-4: a novel mechanism of inflammatory pain modulation. Br J Pharmacol (2006) 1.15
Inhibition of transiently expressed low- and high-voltage-activated calcium channels by trivalent metal cations. J Membr Biol (2002) 1.14
G protein modulation of N-type calcium channels is facilitated by physical interactions between syntaxin 1A and Gbetagamma. J Biol Chem (2000) 1.13
Protection of ischemic rat spinal cord white matter: Dual action of KB-R7943 on Na+/Ca2+ exchange and L-type Ca2+ channels. Neuropharmacology (2005) 1.10
Interaction of SNX482 with domains III and IV inhibits activation gating of alpha(1E) (Ca(V)2.3) calcium channels. Biophys J (2001) 1.10
Identification of an integration center for cross-talk between protein kinase C and G protein modulation of N-type calcium channels. J Biol Chem (1999) 1.09
t-Haplotypes of the mouse may involve a change in intercalary DNA. Nature (1979) 1.07
Distinct molecular determinants govern syntaxin 1A-mediated inactivation and G-protein inhibition of N-type calcium channels. J Neurosci (2001) 1.01
Calcium channel beta subunits differentially regulate the inhibition of N-type channels by individual Gbeta isoforms. J Biol Chem (2001) 1.00
A role for transient receptor potential vanilloid 4 in tonicity-induced neurogenic inflammation. Br J Pharmacol (2010) 0.99
Amino acid residues outside of the pore region contribute to N-type calcium channel permeation. J Biol Chem (2000) 0.98
Residue Gly1326 of the N-type calcium channel alpha 1B subunit controls reversibility of omega-conotoxin GVIA and MVIIA block. J Biol Chem (2001) 0.98
Interactions between presynaptic Ca2+ channels, cytoplasmic messengers and proteins of the synaptic vesicle release complex. Trends Pharmacol Sci (2001) 0.98
The Drosophila cacts2 mutation reduces presynaptic Ca2+ entry and defines an important element in Cav2.1 channel inactivation. Eur J Neurosci (2006) 0.97
Modulation of rod, but not cone, cGMP-gated photoreceptor channels by calcium-calmodulin. Vis Neurosci (1997) 0.96
Identification of inactivation determinants in the domain IIS6 region of high voltage-activated calcium channels. J Biol Chem (2001) 0.94
Temperature dependence of T-type calcium channel gating. Neuroscience (2006) 0.94
Multiple structural domains contribute to voltage-dependent inactivation of rat brain alpha(1E) calcium channels. J Biol Chem (1999) 0.92
Determinants of the differential gating properties of Cav3.1 and Cav3.3 T-type channels: a role of domain IV? Neuroscience (2006) 0.88
Modulation of neuronal voltage-gated calcium channels by farnesol. J Biol Chem (1999) 0.88
Syntaxin 1A supports voltage-dependent inhibition of alpha1B Ca2+ channels by Gbetagamma in chick sensory neurons. J Neurosci (2001) 0.88
Cross-talk between G-protein and protein kinase C modulation of N-type calcium channels is dependent on the G-protein beta subunit isoform. J Biol Chem (2000) 0.87
Multiple structural elements contribute to voltage-dependent facilitation of neuronal alpha 1C (CaV1.2) L-type calcium channels. Neuropharmacology (2001) 0.86
Voltage-dependent calcium channels--beyond dihydropyridine antagonists. Curr Opin Pharmacol (2001) 0.84
Block of voltage-dependent calcium channel by the green mamba toxin calcicludine. J Membr Biol (2000) 0.83
N-type calcium channel blockers: novel therapeutics for the treatment of pain. Med Chem (2006) 0.82
Complementation reactions of a lethal mouse t-haplotype believed to include a deletion. Genet Res (1979) 0.80
Inhibition of neuronal calcium channels by a novel peptide spider toxin, DW13.3. Mol Pharmacol (1998) 0.80
Characterization of human recombinant annexin II tetramer purified from bacteria: role of N-terminal acetylation. Biochemistry (1997) 0.79
Molecular and kinetic determinants of local anaesthetic action on sodium channels. Toxicol Lett (1998) 0.77
Osteoblasts derived from load-bearing bones of the rat express both L- and T-like voltage-operated calcium channels and mRNA for alpha 1C, alpha 1D and alpha 1G subunits. Pflugers Arch (1999) 0.77
Arrhythmias during phenol therapies: a specific action on cardiac sodium channels? Circulation (1994) 0.76
Lens opacity: a new gene for congenital cataract on chromosome 10 of the mouse. Genet Res (1981) 0.76
Block of voltage-dependent calcium channels by aliphatic monoamines. Biophys J (2000) 0.76