Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
1
|
Interactions between heterologous helix-loop-helix proteins generate complexes that bind specifically to a common DNA sequence.
|
Cell
|
1989
|
14.24
|
2
|
Primary structure and functional expression of a mouse inward rectifier potassium channel.
|
Nature
|
1993
|
8.20
|
3
|
A new ER trafficking signal regulates the subunit stoichiometry of plasma membrane K(ATP) channels.
|
Neuron
|
1999
|
6.13
|
4
|
Distinct morphogenetic functions of similar small GTPases: Drosophila Drac1 is involved in axonal outgrowth and myoblast fusion.
|
Genes Dev
|
1994
|
5.71
|
5
|
Asymmetric distribution of numb protein during division of the sensory organ precursor cell confers distinct fates to daughter cells.
|
Cell
|
1994
|
5.37
|
6
|
Changing subunit composition of heteromeric NMDA receptors during development of rat cortex.
|
Nature
|
1994
|
4.92
|
7
|
Primary structure and functional expression of a rat G-protein-coupled muscarinic potassium channel.
|
Nature
|
1993
|
4.81
|
8
|
Control of daughter cell fates during asymmetric division: interaction of Numb and Notch.
|
Neuron
|
1996
|
4.69
|
9
|
Alteration of voltage-dependence of Shaker potassium channel by mutations in the S4 sequence.
|
Nature
|
1991
|
4.60
|
10
|
Sequence of a probable potassium channel component encoded at Shaker locus of Drosophila.
|
Science
|
1987
|
4.48
|
11
|
Multiple potassium-channel components are produced by alternative splicing at the Shaker locus in Drosophila.
|
Nature
|
1988
|
4.18
|
12
|
Properties of the larval neuromuscular junction in Drosophila melanogaster.
|
J Physiol
|
1976
|
4.18
|
13
|
A trafficking checkpoint controls GABA(B) receptor heterodimerization.
|
Neuron
|
2000
|
3.98
|
14
|
daughterless, a Drosophila gene essential for both neurogenesis and sex determination, has sequence similarities to myc and the achaete-scute complex.
|
Cell
|
1988
|
3.94
|
15
|
Evidence for the formation of heteromultimeric potassium channels in Xenopus oocytes.
|
Nature
|
1990
|
3.88
|
16
|
A protein component of Drosophila polar granules is encoded by vasa and has extensive sequence similarity to ATP-dependent helicases.
|
Cell
|
1988
|
3.87
|
17
|
Antibodies to horseradish peroxidase as specific neuronal markers in Drosophila and in grasshopper embryos.
|
Proc Natl Acad Sci U S A
|
1982
|
3.73
|
18
|
Putative receptor for the cytoplasmic inactivation gate in the Shaker K+ channel.
|
Nature
|
1991
|
3.72
|
19
|
Control of rectification and permeation by residues in two distinct domains in an inward rectifier K+ channel.
|
Neuron
|
1995
|
3.70
|
20
|
Expression of functional potassium channels from Shaker cDNA in Xenopus oocytes.
|
Nature
|
1988
|
3.69
|
21
|
Specification of subunit assembly by the hydrophilic amino-terminal domain of the Shaker potassium channel.
|
Science
|
1992
|
3.53
|
22
|
G protein-coupled inwardly rectifying K+ channels (GIRKs) mediate postsynaptic but not presynaptic transmitter actions in hippocampal neurons.
|
Neuron
|
1997
|
3.52
|
23
|
Cloning of genomic and complementary DNA from Shaker, a putative potassium channel gene from Drosophila.
|
Science
|
1987
|
3.33
|
24
|
atonal is a proneural gene that directs chordotonal organ formation in the Drosophila peripheral nervous system.
|
Cell
|
1993
|
3.24
|
25
|
Activation of the cloned muscarinic potassium channel by G protein beta gamma subunits.
|
Nature
|
1994
|
3.21
|
26
|
Functional dissociation of mu opioid receptor signaling and endocytosis: implications for the biology of opiate tolerance and addiction.
|
Neuron
|
1999
|
3.15
|
27
|
Atonal is the proneural gene for Drosophila photoreceptors.
|
Nature
|
1994
|
3.11
|
28
|
L-glutamate as an excitatory transmitter at the Drosophila larval neuromuscular junction.
|
J Physiol
|
1976
|
3.01
|
29
|
Subcellular segregation of two A-type K+ channel proteins in rat central neurons.
|
Neuron
|
1992
|
2.98
|
30
|
HLH proteins, fly neurogenesis, and vertebrate myogenesis.
|
Cell
|
1993
|
2.93
|
31
|
Role of ER export signals in controlling surface potassium channel numbers.
|
Science
|
2001
|
2.93
|
32
|
A peptide as a possible transmitter in sympathetic ganglia of the frog.
|
Proc Natl Acad Sci U S A
|
1979
|
2.89
|
33
|
Molecular basis for interactions of G protein betagamma subunits with effectors.
|
Science
|
1998
|
2.88
|
34
|
Asymmetric segregation of Numb and Prospero during cell division.
|
Nature
|
1995
|
2.87
|
35
|
Role of inscuteable in orienting asymmetric cell divisions in Drosophila.
|
Nature
|
1996
|
2.87
|
36
|
Asymmetric localization of a mammalian numb homolog during mouse cortical neurogenesis.
|
Neuron
|
1996
|
2.84
|
37
|
numb, a gene required in determination of cell fate during sensory organ formation in Drosophila embryos.
|
Cell
|
1989
|
2.72
|
38
|
frazzled encodes a Drosophila member of the DCC immunoglobulin subfamily and is required for CNS and motor axon guidance.
|
Cell
|
1996
|
2.69
|
39
|
Postembryonic patterns of expression of cut, a locus regulating sensory organ identity in Drosophila.
|
Development
|
1993
|
2.66
|
40
|
Two mutations of synaptic transmission in Drosophila.
|
Proc R Soc Lond B Biol Sci
|
1977
|
2.60
|
41
|
Genes regulating dendritic outgrowth, branching, and routing in Drosophila.
|
Genes Dev
|
1999
|
2.56
|
42
|
Cloning of a probable potassium channel gene from mouse brain.
|
Nature
|
1988
|
2.49
|
43
|
A superfamily of ion channels.
|
Nature
|
1990
|
2.49
|
44
|
Primary structure and expression of a product from cut, a locus involved in specifying sensory organ identity in Drosophila.
|
Nature
|
1988
|
2.47
|
45
|
Adherens junctions inhibit asymmetric division in the Drosophila epithelium.
|
Nature
|
2001
|
2.40
|
46
|
Genome-wide study of aging and oxidative stress response in Drosophila melanogaster.
|
Proc Natl Acad Sci U S A
|
2000
|
2.39
|
47
|
Differential effects of the Rac GTPase on Purkinje cell axons and dendritic trunks and spines.
|
Nature
|
1996
|
2.37
|
48
|
The Drosophila Numb protein inhibits signaling of the Notch receptor during cell-cell interaction in sensory organ lineage.
|
Proc Natl Acad Sci U S A
|
1996
|
2.35
|
49
|
Role of neurogenic genes in establishment of follicle cell fate and oocyte polarity during oogenesis in Drosophila.
|
Cell
|
1991
|
2.33
|
50
|
Transformation of sensory organs by mutations of the cut locus of D. melanogaster.
|
Cell
|
1987
|
2.33
|
51
|
rhomboid, a gene required for dorsoventral axis establishment and peripheral nervous system development in Drosophila melanogaster.
|
Genes Dev
|
1990
|
2.31
|
52
|
Evidence that direct binding of G beta gamma to the GIRK1 G protein-gated inwardly rectifying K+ channel is important for channel activation.
|
Neuron
|
1995
|
2.29
|
53
|
Evidence that the S6 segment of the Shaker voltage-gated K+ channel comprises part of the pore.
|
Nature
|
1994
|
2.25
|
54
|
Role of the proneural gene, atonal, in formation of Drosophila chordotonal organs and photoreceptors.
|
Development
|
1995
|
2.25
|
55
|
Similarity of the product of the Drosophila neurogenic gene big brain to transmembrane channel proteins.
|
Nature
|
1990
|
2.22
|
56
|
Identification of a titratable lysine residue that determines sensitivity of kidney potassium channels (ROMK) to intracellular pH.
|
EMBO J
|
1996
|
2.21
|
57
|
Determination of the subunit stoichiometry of an inwardly rectifying potassium channel.
|
Neuron
|
1995
|
2.19
|
58
|
Hydrophobic substitution mutations in the S4 sequence alter voltage-dependent gating in Shaker K+ channels.
|
Neuron
|
1991
|
2.18
|
59
|
Patterns of expression of cut, a protein required for external sensory organ development in wild-type and cut mutant Drosophila embryos.
|
Genes Dev
|
1990
|
2.16
|
60
|
Transient posterior localization of a kinesin fusion protein reflects anteroposterior polarity of the Drosophila oocyte.
|
Curr Biol
|
1994
|
2.15
|
61
|
Drosophila Stardust interacts with Crumbs to control polarity of epithelia but not neuroblasts.
|
Nature
|
2001
|
2.11
|
62
|
prospero is expressed in neuronal precursors and encodes a nuclear protein that is involved in the control of axonal outgrowth in Drosophila.
|
Cell
|
1991
|
2.08
|
63
|
Control of dendritic field formation in Drosophila: the roles of flamingo and competition between homologous neurons.
|
Neuron
|
2000
|
2.06
|
64
|
Transmembrane structure of an inwardly rectifying potassium channel.
|
Cell
|
1999
|
2.02
|
65
|
Reciprocal localization of Nod and kinesin fusion proteins indicates microtubule polarity in the Drosophila oocyte, epithelium, neuron and muscle.
|
Development
|
1997
|
2.00
|
66
|
M channel KCNQ2 subunits are localized to key sites for control of neuronal network oscillations and synchronization in mouse brain.
|
J Neurosci
|
2001
|
1.94
|
67
|
Asymmetric cell division.
|
Nature
|
1998
|
1.92
|
68
|
The S4-S5 loop contributes to the ion-selective pore of potassium channels.
|
Neuron
|
1993
|
1.91
|
69
|
Presynaptic A-current based on heteromultimeric K+ channels detected in vivo.
|
Nature
|
1993
|
1.90
|
70
|
The polar T1 interface is linked to conformational changes that open the voltage-gated potassium channel.
|
Cell
|
2000
|
1.90
|
71
|
Four cDNA clones from the Shaker locus of Drosophila induce kinetically distinct A-type potassium currents in Xenopus oocytes.
|
Neuron
|
1988
|
1.88
|
72
|
Normal cerebellar development but susceptibility to seizures in mice lacking G protein-coupled, inwardly rectifying K+ channel GIRK2.
|
Proc Natl Acad Sci U S A
|
1997
|
1.88
|
73
|
Regions responsible for the assembly of inwardly rectifying potassium channels.
|
Cell
|
1996
|
1.87
|
74
|
Cell interactions and gene interactions in peripheral neurogenesis.
|
Genes Dev
|
1993
|
1.87
|
75
|
Peptidergic transmission in sympathetic ganglia of the frog.
|
J Physiol
|
1982
|
1.86
|
76
|
Functional effects of the mouse weaver mutation on G protein-gated inwardly rectifying K+ channels.
|
Neuron
|
1996
|
1.85
|
77
|
Delta is a ventral to dorsal signal complementary to Serrate, another Notch ligand, in Drosophila wing formation.
|
Genes Dev
|
1996
|
1.82
|
78
|
Yeast screen for constitutively active mutant G protein-activated potassium channels.
|
Neuron
|
2001
|
1.82
|
79
|
Differential expression of mammalian Numb, Numblike and Notch1 suggests distinct roles during mouse cortical neurogenesis.
|
Development
|
1997
|
1.82
|
80
|
Images of purified Shaker potassium channels.
|
Curr Biol
|
1994
|
1.80
|
81
|
lola encodes a putative transcription factor required for axon growth and guidance in Drosophila.
|
Development
|
1994
|
1.80
|
82
|
Contrasting subcellular localization of the Kv1.2 K+ channel subunit in different neurons of rat brain.
|
J Neurosci
|
1994
|
1.76
|
83
|
Probing ion permeation and gating in a K+ channel with backbone mutations in the selectivity filter.
|
Nat Neurosci
|
2001
|
1.76
|
84
|
deadpan, an essential pan-neural gene in Drosophila, encodes a helix-loop-helix protein similar to the hairy gene product.
|
Genes Dev
|
1992
|
1.75
|
85
|
A new homeobox-containing gene, msh-2, is transiently expressed early during mesoderm formation of Drosophila.
|
Development
|
1990
|
1.74
|
86
|
Molecular basis for K(ATP) assembly: transmembrane interactions mediate association of a K+ channel with an ABC transporter.
|
Neuron
|
2000
|
1.74
|
87
|
Probing the G-protein regulation of GIRK1 and GIRK4, the two subunits of the KACh channel, using functional homomeric mutants.
|
J Biol Chem
|
1997
|
1.73
|
88
|
Miranda is required for the asymmetric localization of Prospero during mitosis in Drosophila.
|
Cell
|
1997
|
1.72
|
89
|
A genomewide survey of basic helix-loop-helix factors in Drosophila.
|
Proc Natl Acad Sci U S A
|
2000
|
1.72
|
90
|
The tko locus, site of a behavioral mutation in D. melanogaster, codes for a protein homologous to prokaryotic ribosomal protein S12.
|
Cell
|
1987
|
1.71
|
91
|
Xath5 participates in a network of bHLH genes in the developing Xenopus retina.
|
Neuron
|
1997
|
1.70
|
92
|
Localization of vasa, a component of Drosophila polar granules, in maternal-effect mutants that alter embryonic anteroposterior polarity.
|
Development
|
1990
|
1.69
|
93
|
Assembly of voltage-gated potassium channels. Conserved hydrophilic motifs determine subfamily-specific interactions between the alpha-subunits.
|
J Biol Chem
|
1995
|
1.69
|
94
|
Stabilization of ion selectivity filter by pore loop ion pairs in an inwardly rectifying potassium channel.
|
Proc Natl Acad Sci U S A
|
1997
|
1.67
|
95
|
Analysis of endoplasmic reticulum trafficking signals by combinatorial screening in mammalian cells.
|
Proc Natl Acad Sci U S A
|
2001
|
1.65
|
96
|
asense is a Drosophila neural precursor gene and is capable of initiating sense organ formation.
|
Development
|
1993
|
1.60
|
97
|
Asymmetric cell division in the Drosophila nervous system.
|
Nat Rev Neurosci
|
2001
|
1.60
|
98
|
Further evidence for peptidergic transmission in sympathetic ganglia.
|
Proc Natl Acad Sci U S A
|
1980
|
1.59
|
99
|
Identification of a component of Drosophila polar granules.
|
Development
|
1988
|
1.58
|
100
|
Partner of Numb colocalizes with Numb during mitosis and directs Numb asymmetric localization in Drosophila neural and muscle progenitors.
|
Cell
|
1998
|
1.57
|
101
|
A Drosophila mutant with a temperature-sensitive block in nerve conduction.
|
Proc Natl Acad Sci U S A
|
1978
|
1.57
|
102
|
deadpan, an essential pan-neural gene encoding an HLH protein, acts as a denominator in Drosophila sex determination.
|
Cell
|
1992
|
1.55
|
103
|
Heteromultimerization of G-protein-gated inwardly rectifying K+ channel proteins GIRK1 and GIRK2 and their altered expression in weaver brain.
|
J Neurosci
|
1996
|
1.54
|
104
|
The Drosophila neurogenic gene neuralized encodes a novel protein and is expressed in precursors of larval and adult neurons.
|
EMBO J
|
1991
|
1.53
|
105
|
The maternal sex determination gene daughterless has zygotic activity necessary for the formation of peripheral neurons in Drosophila.
|
Genes Dev
|
1988
|
1.53
|
106
|
A gain-of-function screen for genes that affect the development of the Drosophila adult external sensory organ.
|
Genetics
|
2000
|
1.52
|
107
|
Transformation of sensory organ identity by ectopic expression of Cut in Drosophila.
|
Genes Dev
|
1991
|
1.52
|
108
|
Identification of structural elements involved in G protein gating of the GIRK1 potassium channel.
|
Neuron
|
1995
|
1.51
|
109
|
Genetic control of cell fate specification in Drosophila peripheral nervous system.
|
Annu Rev Genet
|
1994
|
1.51
|
110
|
Colocalization and coassembly of two human brain M-type potassium channel subunits that are mutated in epilepsy.
|
Proc Natl Acad Sci U S A
|
2000
|
1.50
|
111
|
Mouse numb is an essential gene involved in cortical neurogenesis.
|
Proc Natl Acad Sci U S A
|
2000
|
1.49
|
112
|
Transcriptional regulation of atonal during development of the Drosophila peripheral nervous system.
|
Development
|
1998
|
1.49
|
113
|
A new factor related to TATA-binding protein has highly restricted expression patterns in Drosophila.
|
Nature
|
1993
|
1.48
|
114
|
Regulation of ATP-sensitive potassium channel function by protein kinase A-mediated phosphorylation in transfected HEK293 cells.
|
EMBO J
|
2000
|
1.46
|
115
|
Evidence that the nucleotide exchange and hydrolysis cycle of G proteins causes acute desensitization of G-protein gated inward rectifier K+ channels.
|
Proc Natl Acad Sci U S A
|
1998
|
1.46
|
116
|
Functional expression of Shaker K+ channels in a baculovirus-infected insect cell line.
|
Neuron
|
1990
|
1.42
|
117
|
Characterization of a mammalian cDNA for an inactivating voltage-sensitive K+ channel.
|
Neuron
|
1991
|
1.42
|
118
|
Presynaptic localization of Kv1.4-containing A-type potassium channels near excitatory synapses in the hippocampus.
|
J Neurosci
|
1998
|
1.40
|
119
|
Rho family GTP-binding proteins in growth cone signalling.
|
Curr Opin Neurobiol
|
1997
|
1.39
|
120
|
Differential expression of K+ channel mRNAs in the rat brain and down-regulation in the hippocampus following seizures.
|
Neuron
|
1992
|
1.39
|
121
|
The germ cell-less gene product: a posteriorly localized component necessary for germ cell development in Drosophila.
|
Cell
|
1992
|
1.38
|
122
|
Function of GB1 and GB2 subunits in G protein coupling of GABA(B) receptors.
|
Proc Natl Acad Sci U S A
|
2001
|
1.36
|
123
|
Ion channel genes and human neurological disease: recent progress, prospects, and challenges.
|
Proc Natl Acad Sci U S A
|
1999
|
1.35
|
124
|
Genes required for specifying cell fates in Drosophila embryonic sensory nervous system.
|
Trends Neurosci
|
1990
|
1.34
|
125
|
Immunohistochemical localization of GABA(B) receptors in the rat central nervous system.
|
J Comp Neurol
|
1999
|
1.32
|
126
|
The regulation and function of the helix-loop-helix gene, asense, in Drosophila neural precursors.
|
Development
|
1993
|
1.32
|
127
|
The N terminus of the Drosophila Numb protein directs membrane association and actin-dependent asymmetric localization.
|
Proc Natl Acad Sci U S A
|
1997
|
1.29
|
128
|
Two types of asymmetric divisions in the Drosophila sensory organ precursor cell lineage.
|
Nat Cell Biol
|
2001
|
1.27
|
129
|
Ultrastructural localization of rhodopsin in the vertebrate retina.
|
J Cell Biol
|
1974
|
1.27
|
130
|
Binding of the G protein betagamma subunit to multiple regions of G protein-gated inward-rectifying K+ channels.
|
FEBS Lett
|
1997
|
1.26
|
131
|
tramtrack acts downstream of numb to specify distinct daughter cell fates during asymmetric cell divisions in the Drosophila PNS.
|
Neuron
|
1995
|
1.26
|
132
|
An artificial tetramerization domain restores efficient assembly of functional Shaker channels lacking T1.
|
Proc Natl Acad Sci U S A
|
2000
|
1.25
|
133
|
Neuronal cell fate specification in Drosophila.
|
Curr Opin Neurobiol
|
1994
|
1.25
|
134
|
Evidence for presynaptic N-methyl-D-aspartate autoreceptors in the spinal cord dorsal horn.
|
Proc Natl Acad Sci U S A
|
1994
|
1.25
|
135
|
Neuronal type information encoded in the basic-helix-loop-helix domain of proneural genes.
|
Proc Natl Acad Sci U S A
|
1996
|
1.25
|
136
|
Only a subset of the binary cell fate decisions mediated by Numb/Notch signaling in Drosophila sensory organ lineage requires Suppressor of Hairless.
|
Development
|
1997
|
1.25
|
137
|
Modes of protein movement that lead to the asymmetric localization of partner of Numb during Drosophila neuroblast division.
|
Mol Cell
|
1999
|
1.25
|
138
|
Contributions of a negatively charged residue in the hydrophobic domain of the IRK1 inwardly rectifying K+ channel to K(+)-selective permeation.
|
Biophys J
|
1996
|
1.24
|
139
|
Spatially localized rhomboid is required for establishment of the dorsal-ventral axis in Drosophila oogenesis.
|
Cell
|
1993
|
1.22
|
140
|
Scanning mutagenesis of the putative transmembrane segments of Kir2.1, an inward rectifier potassium channel.
|
Proc Natl Acad Sci U S A
|
1997
|
1.22
|
141
|
Germ cell-less encodes a cell type-specific nuclear pore-associated protein and functions early in the germ-cell specification pathway of Drosophila.
|
Genes Dev
|
1994
|
1.22
|
142
|
dpa, a member of the MCM family, is required for mitotic DNA replication but not endoreplication in Drosophila.
|
EMBO J
|
1995
|
1.22
|
143
|
Peptidergic transmitters in synaptic boutons of sympathetic ganglia.
|
Nature
|
1980
|
1.21
|
144
|
Genetic dissection of short-term and long-term facilitation at the Drosophila neuromuscular junction.
|
Proc Natl Acad Sci U S A
|
1978
|
1.20
|
145
|
Numb-associated kinase interacts with the phosphotyrosine binding domain of Numb and antagonizes the function of Numb in vivo.
|
Mol Cell Biol
|
1998
|
1.19
|
146
|
Mutations that affect the length, fasciculation, or ventral orientation of specific sensory axons in the Drosophila embryo.
|
Neuron
|
1995
|
1.19
|
147
|
The Drosophila LIM-only gene, dLMO, is mutated in Beadex alleles and might represent an evolutionarily conserved function in appendage development.
|
Proc Natl Acad Sci U S A
|
1998
|
1.18
|
148
|
A rat gene with sequence homology to the Drosophila gene hairy is rapidly induced by growth factors known to influence neuronal differentiation.
|
Mol Cell Biol
|
1993
|
1.18
|
149
|
Miranda as a multidomain adapter linking apically localized Inscuteable and basally localized Staufen and Prospero during asymmetric cell division in Drosophila.
|
Genes Dev
|
1998
|
1.16
|
150
|
Ligand-induced signal transduction within heterodimeric GABA(B) receptor.
|
Proc Natl Acad Sci U S A
|
2001
|
1.15
|
151
|
Delta and Serrate are redundant Notch ligands required for asymmetric cell divisions within the Drosophila sensory organ lineage.
|
Genes Dev
|
1998
|
1.15
|
152
|
Bazooka and atypical protein kinase C are required to regulate oocyte differentiation in the Drosophila ovary.
|
Proc Natl Acad Sci U S A
|
2001
|
1.15
|
153
|
Sequoia, a tramtrack-related zinc finger protein, functions as a pan-neural regulator for dendrite and axon morphogenesis in Drosophila.
|
Dev Cell
|
2001
|
1.12
|
154
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