Published in Proc Natl Acad Sci U S A on September 12, 2000
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Juvenile hormone resistance gene Methoprene-tolerant controls entry into metamorphosis in the beetle Tribolium castaneum. Proc Natl Acad Sci U S A (2007) 2.01
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Dissecting differential gene expression within the circadian neuronal circuit of Drosophila. Nat Neurosci (2009) 1.43
From fate to function: the Drosophila trachea and salivary gland as models for tubulogenesis. Differentiation (2006) 1.27
Evolution of the holozoan ribosome biogenesis regulon. BMC Genomics (2008) 1.25
The Drosophila basic helix-loop-helix protein DIMMED directly activates PHM, a gene encoding a neuropeptide-amidating enzyme. Mol Cell Biol (2007) 1.16
Paralogous genes involved in juvenile hormone action in Drosophila melanogaster. Genetics (2010) 1.09
Interaction between hormonal signaling pathways in Drosophila melanogaster as revealed by genetic interaction between methoprene-tolerant and broad-complex. Genetics (2005) 1.08
Sequence signatures and the probabilistic identification of proteins in the Myc-Max-Mad network. Proc Natl Acad Sci U S A (2005) 1.06
Ciona intestinalis as a model for cardiac development. Semin Cell Dev Biol (2006) 1.06
Subdivision and developmental fate of the head mesoderm in Drosophila melanogaster. Dev Genes Evol (2005) 1.02
Expression, regulation, and requirement of the toll transmembrane protein during dorsal vessel formation in Drosophila melanogaster. Mol Cell Biol (2005) 1.02
Identification of the bHLH factor Math6 as a novel component of the embryonic pancreas transcriptional network. PLoS One (2008) 1.00
Functional characterization of PAS and HES family bHLH transcription factors during the metamorphosis of the red flour beetle, Tribolium castaneum. Gene (2009) 0.99
Drosophila melanogaster Methoprene-tolerant (Met) gene homologs from three mosquito species: Members of PAS transcriptional factor family. J Insect Physiol (2006) 0.99
Wide mutational spectrum of a gene involved in hormone action and insecticide resistance in Drosophila melanogaster. Mol Genet Genomics (2006) 0.98
The basic helix-loop-helix leucine zipper transcription factor Mitf is conserved in Drosophila and functions in eye development. Genetics (2004) 0.98
Comparing the yeast retrograde response and NF-κB stress responses: implications for aging. Aging Cell (2010) 0.96
Roles of USF, Ikaros and Sp proteins in the transcriptional regulation of the human reduced folate carrier B promoter. Biochem J (2004) 0.94
The Enhancer of split and Achaete-Scute complexes of Drosophilids derived from simple ur-complexes preserved in mosquito and honeybee. BMC Evol Biol (2005) 0.92
her11 is involved in the somitogenesis clock in zebrafish. Dev Genes Evol (2004) 0.91
The Drosophila STUbL protein Degringolade limits HES functions during embryogenesis. Development (2011) 0.90
The Drosophila Hand gene is required for remodeling of the developing adult heart and midgut during metamorphosis. Dev Biol (2007) 0.88
Evolution of a genomic regulatory domain: the role of gene co-option and gene duplication in the Enhancer of split complex. Genome Res (2010) 0.87
Maternal Groucho and bHLH repressors amplify the dose-sensitive X chromosome signal in Drosophila sex determination. Dev Biol (2008) 0.87
The Drosophila juvenile hormone receptor candidates methoprene-tolerant (MET) and germ cell-expressed (GCE) utilize a conserved LIXXL motif to bind the FTZ-F1 nuclear receptor. J Biol Chem (2012) 0.87
Mining gene expression data for pollutants (dioxin, toluene, formaldehyde) and low dose of gamma-irradiation. PLoS One (2014) 0.83
Islet1-expressing cardiac progenitor cells: a comparison across species. Dev Genes Evol (2012) 0.82
Building and specializing epithelial tubular organs: the Drosophila salivary gland as a model system for revealing how epithelial organs are specified, form and specialize. Wiley Interdiscip Rev Dev Biol (2014) 0.82
Organ-specific gene expression: the bHLH protein Sage provides tissue specificity to Drosophila FoxA. Development (2013) 0.81
Hox targets and cellular functions. Scientifica (Cairo) (2013) 0.81
Effects of hormone agonists on Sf9 cells, proliferation and cell cycle arrest. PLoS One (2011) 0.80
The members of bHLH transcription factor superfamily are required for female reproduction in the red flour beetle, Tribolium castaneum. J Insect Physiol (2010) 0.80
A genomewide survey of bHLH transcription factors in the coral Acropora digitifera identifies three novel orthologous families, pearl, amber, and peridot. Dev Genes Evol (2012) 0.80
Regulation of locomotion and motoneuron trajectory selection and targeting by the Drosophila homolog of Olig family transcription factors. Dev Biol (2012) 0.79
Synergistic role of specificity proteins and upstream stimulatory factor 1 in transactivation of the mouse carboxylesterase 2/microsomal acylcarnitine hydrolase gene promoter. Biochem J (2004) 0.78
Hand is a direct target of the forkhead transcription factor Biniou during Drosophila visceral mesoderm differentiation. BMC Dev Biol (2007) 0.78
Mapping of the Sequences Directing Localization of the Drosophila Germ Cell-Expressed Protein (GCE). PLoS One (2015) 0.78
Combined informatic and expression screen identifies the novel DAF-16 target HLH-13. Dev Biol (2008) 0.77
Two adjacent cis-regulatory elements are required for ecdysone response of ecdysone receptor (EcR) B1 transcription. PLoS One (2012) 0.77
Two Figla homologues have disparate functions during sex differentiation in half-smooth tongue sole (Cynoglossus semilaevis). Sci Rep (2016) 0.77
Molecular Mechanisms of Transcription Activation by Juvenile Hormone: A Critical Role for bHLH-PAS and Nuclear Receptor Proteins. Insects (2012) 0.77
Phosphorylation Regulates Id2 Degradation and Mediates the Proliferation of Neural Precursor Cells. Stem Cells (2016) 0.77
The bHLH Transcription Factor Hand Regulates the Expression of Genes Critical to Heart and Muscle Function in Drosophila melanogaster. PLoS One (2015) 0.76
Genome-wide identification and analysis of basic helix-loop-helix domains in dog, Canis lupus familiaris. Mol Genet Genomics (2014) 0.75
Genetic tools to study juvenile hormone action in Drosophila. Sci Rep (2017) 0.75
A Genome-Wide Identification and Analysis of the Basic Helix-Loop-Helix Transcription Factors in Brown Planthopper, Nilaparvata lugens. Genes (Basel) (2016) 0.75
Intrinsic Disorder of the C-Terminal Domain of Drosophila Methoprene-Tolerant Protein. PLoS One (2016) 0.75
Hypoxia Inducible Factor (HIF) transcription factor family expansion, diversification, divergence and selection in eukaryotes. PLoS One (2017) 0.75
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The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools. Nucleic Acids Res (1997) 175.36
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A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins. Cell (1989) 21.54
A non-radioactive in situ hybridization method for the localization of specific RNAs in Drosophila embryos reveals translational control of the segmentation gene hunchback. Chromosoma (1989) 16.41
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Molecular bases for circadian clocks. Cell (1999) 13.96
Differences and similarities in DNA-binding preferences of MyoD and E2A protein complexes revealed by binding site selection. Science (1990) 9.54
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The adenovirus major late transcription factor USF is a member of the helix-loop-helix group of regulatory proteins and binds to DNA as a dimer. Genes Dev (1990) 6.88
Control of mouse cardiac morphogenesis and myogenesis by transcription factor MEF2C. Science (1997) 5.54
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The gene tinman is required for specification of the heart and visceral muscles in Drosophila. Development (1993) 4.11
Identification of a novel family of oligodendrocyte lineage-specific basic helix-loop-helix transcription factors. Neuron (2000) 3.91
Regulation of cardiac mesodermal and neural crest development by the bHLH transcription factor, dHAND. Nat Genet (1997) 3.89
Requirement of MADS domain transcription factor D-MEF2 for muscle formation in Drosophila. Science (1995) 3.64
A natural classification of the basic helix-loop-helix class of transcription factors. Proc Natl Acad Sci U S A (1997) 3.52
Crystal structure of MyoD bHLH domain-DNA complex: perspectives on DNA recognition and implications for transcriptional activation. Cell (1994) 3.50
Crystal structure of transcription factor E47: E-box recognition by a basic region helix-loop-helix dimer. Genes Dev (1994) 3.30
Discrimination between related DNA sites by a single amino acid residue of Myc-related basic-helix-loop-helix proteins. Proc Natl Acad Sci U S A (1992) 3.25
atonal is a proneural gene that directs chordotonal organ formation in the Drosophila peripheral nervous system. Cell (1993) 3.24
Drosophila MEF2, a transcription factor that is essential for myogenesis. Genes Dev (1995) 3.16
A subclass of bHLH proteins required for cardiac morphogenesis. Science (1995) 2.39
Basic helix-loop-helix genes in neural development. Curr Opin Neurobiol (1997) 2.32
Positional dependence, cliques, and predictive motifs in the bHLH protein domain. J Mol Evol (1999) 2.31
The p48 DNA-binding subunit of transcription factor PTF1 is a new exocrine pancreas-specific basic helix-loop-helix protein. EMBO J (1996) 2.28
twist: a myogenic switch in Drosophila. Science (1996) 2.28
Insect juvenile hormone resistance gene homology with the bHLH-PAS family of transcriptional regulators. Proc Natl Acad Sci U S A (1998) 2.23
Mesp2: a novel mouse gene expressed in the presegmented mesoderm and essential for segmentation initiation. Genes Dev (1997) 1.97
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amos, a proneural gene for Drosophila olfactory sense organs that is regulated by lozenge. Neuron (2000) 1.90
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The proneural gene amos promotes multiple dendritic neuron formation in the Drosophila peripheral nervous system. Neuron (2000) 1.74
Shaping animal body plans in development and evolution by modulation of Hox expression patterns. Bioessays (1998) 1.64
The function of hairy-related bHLH repressor proteins in cell fate decisions. Bioessays (1998) 1.60
Remembrance of things PAS: regulation of development by bHLH-PAS proteins. Curr Opin Genet Dev (1999) 1.55
Control of cell proliferation by Myc. Trends Cell Biol (1998) 1.52
D-mef2 is a target for Tinman activation during Drosophila heart development. EMBO J (1997) 1.38
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Mist1: a novel basic helix-loop-helix transcription factor exhibits a developmentally regulated expression pattern. Dev Biol (1997) 1.21
BETA3, a novel helix-loop-helix protein, can act as a negative regulator of BETA2 and MyoD-responsive genes. Mol Cell Biol (1996) 1.12
cato encodes a basic helix-loop-helix transcription factor implicated in the correct differentiation of Drosophila sense organs. Dev Biol (2000) 1.03
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Biparous: a novel bHLH gene expressed in neuronal and glial precursors in Drosophila. Dev Biol (1996) 0.88
Two new Drosophila genes related to human hematopoietic and neurogenic transcription factors. Cell Growth Differ (1993) 0.82
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Primary structure and functional expression of a mouse inward rectifier potassium channel. Nature (1993) 8.20
Searching for pattern and mutation in the Drosophila genome with a P-lacZ vector. Genes Dev (1989) 6.81
A new ER trafficking signal regulates the subunit stoichiometry of plasma membrane K(ATP) channels. Neuron (1999) 6.13
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Asymmetric distribution of numb protein during division of the sensory organ precursor cell confers distinct fates to daughter cells. Cell (1994) 5.37
Changing subunit composition of heteromeric NMDA receptors during development of rat cortex. Nature (1994) 4.92
Primary structure and functional expression of a rat G-protein-coupled muscarinic potassium channel. Nature (1993) 4.81
Control of daughter cell fates during asymmetric division: interaction of Numb and Notch. Neuron (1996) 4.69
Alteration of voltage-dependence of Shaker potassium channel by mutations in the S4 sequence. Nature (1991) 4.60
Sequence of a probable potassium channel component encoded at Shaker locus of Drosophila. Science (1987) 4.48
Multiple potassium-channel components are produced by alternative splicing at the Shaker locus in Drosophila. Nature (1988) 4.18
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A trafficking checkpoint controls GABA(B) receptor heterodimerization. Neuron (2000) 3.98
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A protein component of Drosophila polar granules is encoded by vasa and has extensive sequence similarity to ATP-dependent helicases. Cell (1988) 3.87
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Putative receptor for the cytoplasmic inactivation gate in the Shaker K+ channel. Nature (1991) 3.72
Control of rectification and permeation by residues in two distinct domains in an inward rectifier K+ channel. Neuron (1995) 3.70
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Cloning of genomic and complementary DNA from Shaker, a putative potassium channel gene from Drosophila. Science (1987) 3.33
atonal is a proneural gene that directs chordotonal organ formation in the Drosophila peripheral nervous system. Cell (1993) 3.24
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Functional dissociation of mu opioid receptor signaling and endocytosis: implications for the biology of opiate tolerance and addiction. Neuron (1999) 3.15
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