Published in Curr Opin Cell Biol on October 01, 2000
ADAM10 cleavage of N-cadherin and regulation of cell-cell adhesion and beta-catenin nuclear signalling. EMBO J (2005) 2.95
Group 1 mGluR-dependent synaptic long-term depression: mechanisms and implications for circuitry and disease. Neuron (2010) 2.67
Ectodomain shedding of L1 adhesion molecule promotes cell migration by autocrine binding to integrins. J Cell Biol (2001) 2.20
Identification of ARTS-1 as a novel TNFR1-binding protein that promotes TNFR1 ectodomain shedding. J Clin Invest (2002) 2.19
The metalloprotease Kuzbanian (ADAM10) mediates the transactivation of EGF receptor by G protein-coupled receptors. J Cell Biol (2002) 1.99
The Alzheimer's disease beta-secretase enzyme, BACE1. Mol Neurodegener (2007) 1.81
Ectodomain shedding of the glycoprotein GP of Ebola virus. EMBO J (2004) 1.73
A conserved mechanism for extracellular signaling in eukaryotes and prokaryotes. Proc Natl Acad Sci U S A (2002) 1.62
The role of the epithelium in airway remodeling in asthma. Proc Am Thorac Soc (2009) 1.52
Full-length ADAMTS-1 and the ADAMTS-1 fragments display pro- and antimetastatic activity, respectively. Oncogene (2006) 1.49
Ab-induced ectodomain shedding mediates hepatocyte growth factor receptor down-regulation and hampers biological activity. Proc Natl Acad Sci U S A (2006) 1.47
Ectodomain shedding of preadipocyte factor 1 (Pref-1) by tumor necrosis factor alpha converting enzyme (TACE) and inhibition of adipocyte differentiation. Mol Cell Biol (2006) 1.35
mGluR1/5-dependent long-term depression requires the regulated ectodomain cleavage of neuronal pentraxin NPR by TACE. Neuron (2008) 1.31
Injury-induced innate immune response in human skin mediated by transactivation of the epidermal growth factor receptor. J Clin Invest (2006) 1.30
Essential role for ADAM19 in cardiovascular morphogenesis. Mol Cell Biol (2004) 1.27
Regulated proteolytic processing of Tie1 modulates ligand responsiveness of the receptor-tyrosine kinase Tie2. J Biol Chem (2007) 1.25
The low affinity IgE receptor (CD23) is cleaved by the metalloproteinase ADAM10. J Biol Chem (2007) 1.21
Role of ADAMs in the ectodomain shedding and conformational conversion of the prion protein. J Biol Chem (2009) 1.19
Gene expression profiles of microdissected pancreatic ductal adenocarcinoma. Virchows Arch (2003) 1.18
ADAM 12 protease induces adipogenesis in transgenic mice. Am J Pathol (2002) 1.17
ADAM33 is not essential for growth and development and does not modulate allergic asthma in mice. Mol Cell Biol (2006) 1.15
Heparan sulfate-modulated, metalloprotease-mediated sonic hedgehog release from producing cells. J Biol Chem (2009) 1.10
Processing of the synaptic cell adhesion molecule neurexin-3beta by Alzheimer disease alpha- and gamma-secretases. J Biol Chem (2010) 1.03
ADAM12 alleviates the skeletal muscle pathology in mdx dystrophic mice. Am J Pathol (2002) 1.03
The cysteine-rich domain regulates ADAM protease function in vivo. J Cell Biol (2002) 1.00
Mutation of a conserved hydrophobic patch prevents incorporation of ZP3 into the zona pellucida surrounding mouse eggs. Mol Cell Biol (2003) 0.95
Biology of TACE inhibition. Ann Rheum Dis (2001) 0.93
Canonical transforming growth factor-β signaling regulates disintegrin metalloprotease expression in experimental renal fibrosis via miR-29. Am J Pathol (2013) 0.92
The Basic Biology of BACE1: A Key Therapeutic Target for Alzheimer's Disease. Curr Genomics (2007) 0.90
Human colonic myocytes are involved in postischemic inflammation through ADAM17-dependent TNFalpha production. Br J Pharmacol (2006) 0.89
A PKC-dependent recruitment of MMP-2 controls semaphorin-3A growth-promoting effect in cortical dendrites. PLoS One (2009) 0.87
Selective inhibition of ADAM12 catalytic activity through engineering of tissue inhibitor of metalloproteinase 2 (TIMP-2). Biochem J (2010) 0.87
Loss of TIMP3 underlies diabetic nephropathy via FoxO1/STAT1 interplay. EMBO Mol Med (2013) 0.85
Synergistic Regulation of Angiogenic Sprouting by Biochemical Factors and Wall Shear Stress. Cell Mol Bioeng (2011) 0.85
The shed ectodomain of type XIII collagen affects cell behaviour in a matrix-dependent manner. Biochem J (2004) 0.82
Epidermal-growth-factor receptor and metalloproteinases mediate thromboxane A2-dependent extracellular-signal-regulated kinase activation. Biochem J (2003) 0.79
Absence of nicotinic acetylcholine receptor α7 subunit amplifies inflammation and accelerates onset of fibrosis: an inflammatory kidney model. FASEB J (2015) 0.79
Ectodomain shedding of the cell adhesion molecule Nectin-4 in ovarian cancer is mediated by ADAM10 and ADAM17. J Biol Chem (2017) 0.76
ADAM33 gene polymorphisms are associated with the risk of idiopathic pulmonary fibrosis. Lung (2014) 0.76
Genetic variations within metalloproteinases impact on the prophylaxis of depressive phases in bipolar patients. Neuropsychobiology (2014) 0.75
Activation of a latent nuclear localization signal in the NH2 terminus of γ-ENaC initiates feedback regulation of channel activity. Am J Physiol Renal Physiol (2010) 0.75
The production of soluble C-type lectin-like receptor 2 is a regulated process. Glycoconj J (2012) 0.75