Published in Ann Chir Gynaecol on January 01, 2000
Clues to the pathogenesis of familial colorectal cancer. Science (1993) 14.52
New clinical criteria for hereditary nonpolyposis colorectal cancer (HNPCC, Lynch syndrome) proposed by the International Collaborative group on HNPCC. Gastroenterology (1999) 11.94
The International Collaborative Group on Hereditary Non-Polyposis Colorectal Cancer (ICG-HNPCC). Dis Colon Rectum (1991) 9.82
Incidence of hereditary nonpolyposis colorectal cancer and the feasibility of molecular screening for the disease. N Engl J Med (1998) 8.47
Controlled 15-year trial on screening for colorectal cancer in families with hereditary nonpolyposis colorectal cancer. Gastroenterology (2000) 8.41
Effect of the tyrosine kinase inhibitor STI571 in a patient with a metastatic gastrointestinal stromal tumor. N Engl J Med (2001) 7.88
Cancer risk in mutation carriers of DNA-mismatch-repair genes. Int J Cancer (1999) 6.73
Genetic mapping of a locus predisposing to human colorectal cancer. Science (1993) 4.12
Population-based molecular detection of hereditary nonpolyposis colorectal cancer. J Clin Oncol (2000) 3.98
Screening reduces colorectal cancer rate in families with hereditary nonpolyposis colorectal cancer. Gastroenterology (1995) 3.45
Replication errors in benign and malignant tumors from hereditary nonpolyposis colorectal cancer patients. Cancer Res (1994) 3.25
Microsatellite instability is a favorable prognostic indicator in patients with colorectal cancer receiving chemotherapy. Gastroenterology (2000) 3.01
Life-time risk of different cancers in hereditary non-polyposis colorectal cancer (HNPCC) syndrome. Int J Cancer (1995) 2.85
Better survival rates in patients with MLH1-associated hereditary colorectal cancer. Gastroenterology (1996) 2.60
Hepatocyte apoptosis after bile duct ligation in the mouse involves Fas. Gastroenterology (1999) 2.56
Founding mutations and Alu-mediated recombination in hereditary colon cancer. Nat Med (1995) 2.40
Toxic bile salts induce rodent hepatocyte apoptosis via direct activation of Fas. J Clin Invest (1999) 2.32
The release of amino acids with proposed neurotransmitter function from the cuneate and gracile nuclei of the rat in vivo. Brain Res (1974) 2.24
Sequential appearance of fibronectin and collagen in experimental granulation tissue. Lab Invest (1980) 2.16
Microsatellite marker analysis in screening for hereditary nonpolyposis colorectal cancer (HNPCC). Cancer Res (2001) 2.12
Loss of the wild type MLH1 gene is a feature of hereditary nonpolyposis colorectal cancer. Nat Genet (1994) 2.08
Evaluation of CA 19-9 as a serum tumour marker in pancreatic cancer. Br J Cancer (1986) 1.91
The clinical features of ovarian cancer in hereditary nonpolyposis colorectal cancer. Gynecol Oncol (2001) 1.84
Germline mutations in BMPR1A/ALK3 cause a subset of cases of juvenile polyposis syndrome and of Cowden and Bannayan-Riley-Ruvalcaba syndromes. Am J Hum Genet (2001) 1.81
Clinical features of colorectal carcinoma in cancer family syndrome. Dis Colon Rectum (1986) 1.79
The distribution and axonal transport of free amino acids and related compounds in the dorsal sensory neuron of the rat, as determined by the dansyl reaction. J Neurochem (1973) 1.70
DNA mismatch repair gene mutations in 55 kindreds with verified or putative hereditary non-polyposis colorectal cancer. Hum Mol Genet (1996) 1.64
Genetic reconstruction of individual colorectal tumor histories. Proc Natl Acad Sci U S A (2000) 1.63
Impact of clinical symptoms and referral volume on endoscopy for detecting peptic ulcer and gastric neoplasms. Scand J Gastroenterol (2003) 1.57
Comparison of CA 19-9 and carcinoembryonic antigen (CEA) levels in the serum of patients with colorectal diseases. Br J Cancer (1984) 1.56
Bile salts mediate hepatocyte apoptosis by increasing cell surface trafficking of Fas. Am J Physiol Gastrointest Liver Physiol (2000) 1.51
Predictive genetic testing for hereditary non-polyposis colorectal cancer: uptake and long-term satisfaction. Int J Cancer (2000) 1.49
Characteristics of small bowel carcinoma in hereditary nonpolyposis colorectal carcinoma. International Collaborative Group on HNPCC. Cancer (1998) 1.48
Effective dose during screening monitored intussusception reduction. Clin Radiol (1993) 1.47
Gastrointestinal cancer-associated antigen CA 19-9 in histological specimens of pancreatic tumours and pancreatitis. Br J Cancer (1986) 1.45
The prognostic value of preoperative serum levels of CA 19-9 and CEA in patients with pancreatic cancer. Br J Cancer (1994) 1.44
Microsatellite instability in adenomas as a marker for hereditary nonpolyposis colorectal cancer. Am J Pathol (1999) 1.38
A novel approach to estimate the proportion of hereditary nonpolyposis colorectal cancer of total colorectal cancer burden. Cancer Detect Prev (1994) 1.36
Follow-up of patients operated on for colorectal carcinoma. Am J Surg (1990) 1.33
The transforming growth factor beta(1)-inducible transcription factor TIEG1, mediates apoptosis through oxidative stress. Hepatology (1999) 1.32
Serum CA 50 as a tumor marker in pancreatic cancer: a comparison with CA 19-9. Int J Cancer (1987) 1.30
Competitive antagonism at metabotropic glutamate receptors by (S)-4-carboxyphenylglycine and (RS)-alpha-methyl-4-carboxyphenylglycine. Eur J Pharmacol (1993) 1.30
Gastroesophageal reflux disease: prevalence, clinical, endoscopic and histopathological findings in 1,128 consecutive patients referred for endoscopy due to dyspeptic and reflux symptoms. Digestion (2000) 1.27
Comparison of a new tumour marker CA 242 with CA 19-9, CA 50 and carcinoembryonic antigen (CEA) in digestive tract diseases. Br J Cancer (1991) 1.25
Expression of cyclooxygenase-2 in dysplasia of the stomach and in intestinal-type gastric adenocarcinoma. Clin Cancer Res (2001) 1.24
Psychological consequences of predictive genetic testing for hereditary non-polyposis colorectal cancer (HNPCC): a prospective follow-up study. Int J Cancer (2001) 1.23
Presynaptic gamma-aminobutyric acid receptors in the rat anococcygeus muscle and their antagonism by 5-aminovaleric acid. Br J Pharmacol (1982) 1.22
Tissue expression of the tumour associated antigen CA242 in benign and malignant pancreatic lesions. A comparison with CA 50 and CA 19-9. Br J Cancer (1989) 1.18
Close linkage to chromosome 3p and conservation of ancestral founding haplotype in hereditary nonpolyposis colorectal cancer families. Proc Natl Acad Sci U S A (1994) 1.14
Purification and analysis of mitochondrial membrane proteins on nondenaturing gradient polyacrylamide gels. Anal Biochem (1986) 1.14
Reliability of radiographs in defining union of internally fixed fractures. Injury (2004) 1.13
Surveillance improves survival of colorectal cancer in patients with hereditary nonpolyposis colorectal cancer. Cancer Detect Prev (2000) 1.12
Genotype and phenotype in hereditary nonpolyposis colon cancer: a study of families with different vs. shared predisposing mutations. Fam Cancer (2001) 1.11
Histopathology of colorectal carcinomas and adenomas in cancer family syndrome. Dis Colon Rectum (1986) 1.11
No evidence of Peutz-Jeghers syndrome gene LKB1 involvement in left-sided colorectal carcinomas. Cancer Res (2000) 1.11
SMAD genes in juvenile polyposis. Genes Chromosomes Cancer (1999) 1.10
Phenylglycine derivatives as new pharmacological tools for investigating the role of metabotropic glutamate receptors in the central nervous system. Neuroscience (1993) 1.10
The risk of endometrial cancer in hereditary nonpolyposis colorectal cancer. Am J Med (1994) 1.10
Prostaglandin and noradrenaline interactions in rat brain synaptosomes [proceedings]. Br J Pharmacol (1979) 1.09
Demonstration and biochemical characterisation of rat brain NADPH-dependent diaphorase. J Neurochem (1988) 1.09
Does the type of flooring affect the risk of hip fracture? Age Ageing (2004) 1.09
Cancer family syndrome. Genetic analysis of 22 Finnish kindreds. Gastroenterology (1986) 1.09
Development of cytochrome b and an active oxidase system in association with maturation of a human promyelocytic (HL-60) cell line. J Cell Biol (1982) 1.08
European guidelines for quality assurance in the surgical management of mammographically detected lesions. European Breast Cancer Working Group. Ann Chir Gynaecol (1998) 1.07
Activation of human monocytes occurs on cross-linking monocytic antigens to an Fc receptor. J Immunol (1989) 1.06
MSH6 and MSH3 are rarely involved in genetic predisposition to nonpolypotic colon cancer. Cancer Res (2001) 1.06
Features of gastric cancer in hereditary non-polyposis colorectal cancer syndrome. Int J Cancer (1997) 1.06
Tumour-associated trypsin inhibitor, TATI, in patients with pancreatic cancer, pancreatitis and benign biliary diseases. Br J Cancer (1986) 1.06
The uptake and release of [3-H]-2-amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthlane (ADTN) by striatal nerve terminals. Br J Pharmacol (1978) 1.06
CA 242, a new tumour marker for pancreatic cancer: a comparison with CA 19-9, CA 50 and CEA. Br J Cancer (1994) 1.03
Diploid predominance in hereditary nonpolyposis colorectal carcinoma evaluated by flow cytometry. Cancer (1990) 1.03
Cystatin A expression reduces bile salt-induced apoptosis in a rat hepatoma cell line. Am J Physiol (1998) 1.02
Screening for colorectal carcinoma in cancer family syndrome kindreds. Scand J Gastroenterol (1987) 1.01
Childhood cancer and paternal exposure to ionizing radiation: preliminary findings from the Oxford Survey of Childhood Cancers. Am J Ind Med (1993) 1.01
Prognostic value of Ki-67 expression, ploidy and S-phase fraction in patients with pancreatic cancer. Anticancer Res (1996) 1.01
Rat brain NADPH-dependent diaphorase. A possible relationship to cytochrome P450 reductase. Biochem Pharmacol (1988) 1.00
Agonist-induced internalization of the metabotropic glutamate receptor 1a is arrestin- and dynamin-dependent. J Neurochem (2001) 0.99
The epidemiology of endometrial cancer in hereditary nonpolyposis colorectal cancer. Anticancer Res (1994) 0.99
High affinity l-[3h]glutamate binding to postsynaptic receptor sites on rat cerebellar membranes. J Neurochem (1978) 0.99
Mutation sharing, predominant involvement of the MLH1 gene and description of four novel mutations in hereditary nonpolyposis colorectal cancer. Mutations in brief no. 144. Online. Hum Mutat (1998) 0.98
Mechanism of human monocyte activation via the 40-kDa Fc receptor for IgG. J Immunol (1988) 0.98
Tumour markers CA 19-9 and CA 50 in digestive tract malignancies. Scand J Gastroenterol (1992) 0.98
Neurotoxicity of L-glutamate and DL-threo-3-hydroxyaspartate in the rat striatum. J Neurochem (1985) 0.98
Endometrial carcinoma in the cancer family syndrome. Cancer (1991) 0.97
Surveillance in hereditary nonpolyposis colorectal cancer: an international cooperative study of 165 families. The International Collaborative Group on HNPCC. Dis Colon Rectum (1993) 0.97
Evoked release of amino acids from the intact spinal cord. Br J Pharmacol (1972) 0.97
Glutamate-preferring receptors regulate the release of D-[3H]aspartate from rat hippocampal slices. Nature (1981) 0.97
The International Collaborative Group on HNPCC. Anticancer Res (1994) 0.96
Facilitation of noradrenaline release from rat brain synaptosomes by prostaglandin E2. Brain Res (1976) 0.96
Prognosis of colorectal cancer varies in different high-risk conditions. Ann Med (1998) 0.96
Evidence supporting exclusion of the DCC gene and a portion of chromosome 18q as the locus for susceptibility to hereditary nonpolyposis colorectal carcinoma in five kindreds. Cancer Res (1991) 0.96
No support for endoscopic surveillance for gastric cancer in hereditary non-polyposis colorectal cancer. Scand J Gastroenterol (2002) 0.95
Genetic polymorphisms in carcinogen metabolism and their association to hereditary nonpolyposis colon cancer. Gastroenterology (1998) 0.95
Comprehension of cancer risk one and 12 months after predictive genetic testing for hereditary non-polyposis colorectal cancer. J Med Genet (2001) 0.95
Chronic inflammation at the gastroesophageal junction (carditis) appears to be a specific finding related to Helicobacter pylori infection and gastroesophageal reflux disease. The Central Finland Endoscopy Study Group. Am J Gastroenterol (1999) 0.95
Catecholamine-stimulated prostaglandin synthesis in rat brain synaptosomes [proceedings]. Br J Pharmacol (1976) 0.95
Comparison of CA-50, a new tumour marker, with carcinoembryonic antigen (CEA) and alpha-fetoprotein (AFP) in patients with gastrointestinal diseases. Br J Cancer (1987) 0.95
The environment of the lipoxygenase iron binding site explored with novel hydroxypyridinone iron chelators. J Biol Chem (1996) 0.94