Published in Immunol Today on November 01, 2000
Going both ways: immune regulation via CD1d-dependent NKT cells. J Clin Invest (2004) 5.16
Distinct functional lineages of human V(alpha)24 natural killer T cells. J Exp Med (2002) 3.70
CD1d-restricted iNKT cells, the 'Swiss-Army knife' of the immune system. Curr Opin Immunol (2008) 3.37
Blood transfusion promotes cancer progression: a critical role for aged erythrocytes. Anesthesiology (2008) 3.32
A natural killer T (NKT) cell developmental pathway iInvolving a thymus-dependent NK1.1(-)CD4(+) CD1d-dependent precursor stage. J Exp Med (2002) 3.13
Editing of CD1d-bound lipid antigens by endosomal lipid transfer proteins. Science (2003) 3.05
Prevention of autoimmunity by targeting a distinct, noninvariant CD1d-reactive T cell population reactive to sulfatide. J Exp Med (2004) 2.94
Drug-induced autoimmune-like hepatitis. Dig Dis Sci (2011) 2.86
Glycolipid antigen induces long-term natural killer T cell anergy in mice. J Clin Invest (2005) 2.85
Characterization of the early stages of thymic NKT cell development. J Exp Med (2005) 2.84
Modulation of CD1d-restricted NKT cell responses by using N-acyl variants of alpha-galactosylceramides. Proc Natl Acad Sci U S A (2005) 2.83
A critical role for natural killer T cells in immunosurveillance of methylcholanthrene-induced sarcomas. J Exp Med (2002) 2.73
Natural killer T cell activation protects mice against experimental autoimmune encephalomyelitis. J Exp Med (2001) 2.67
Superior protection against malaria and melanoma metastases by a C-glycoside analogue of the natural killer T cell ligand alpha-Galactosylceramide. J Exp Med (2003) 2.64
Adenosine A2A receptor activation reduces hepatic ischemia reperfusion injury by inhibiting CD1d-dependent NKT cell activation. J Exp Med (2006) 2.62
A reversible defect in natural killer T cell function characterizes the progression of premalignant to malignant multiple myeloma. J Exp Med (2003) 2.48
CD1-restricted NK T cells protect nonobese diabetic mice from developing diabetes. J Exp Med (2001) 2.26
CD1d-restricted human natural killer T cells are highly susceptible to human immunodeficiency virus 1 infection. J Exp Med (2002) 2.00
CD1d-dependent activation of NKT cells aggravates atherosclerosis. J Exp Med (2004) 1.80
Differential requirement for Rel/nuclear factor kappa B family members in natural killer T cell development. J Exp Med (2003) 1.77
Selective loss of innate CD4(+) V alpha 24 natural killer T cells in human immunodeficiency virus infection. J Virol (2002) 1.74
An integrated view of suppressor T cell subsets in immunoregulation. J Clin Invest (2004) 1.69
Expansion and long-range differentiation of the NKT cell lineage in mice expressing CD1d exclusively on cortical thymocytes. J Exp Med (2005) 1.67
Characterization of human invariant natural killer T subsets in health and disease using a novel invariant natural killer T cell-clonotypic monoclonal antibody, 6B11. Immunology (2007) 1.63
CD1d-expressing dendritic cells but not thymic epithelial cells can mediate negative selection of NKT cells. J Exp Med (2003) 1.63
Germ line deletion of the CD1 locus exacerbates diabetes in the NOD mouse. Proc Natl Acad Sci U S A (2001) 1.62
The T cell antigen receptor expressed by Valpha14i NKT cells has a unique mode of glycosphingolipid antigen recognition. Proc Natl Acad Sci U S A (2004) 1.61
Cutaneous immunization rapidly activates liver invariant Valpha14 NKT cells stimulating B-1 B cells to initiate T cell recruitment for elicitation of contact sensitivity. J Exp Med (2003) 1.56
The vitamin D receptor is required for iNKT cell development. Proc Natl Acad Sci U S A (2008) 1.50
The CD1d-binding glycolipid alpha-galactosylceramide enhances humoral immunity to T-dependent and T-independent antigen in a CD1d-dependent manner. Immunology (2006) 1.44
Requirement for CD1d expression by B cells to stimulate NKT cell-enhanced antibody production. Blood (2007) 1.43
Natural killer T cells infiltrate neuroblastomas expressing the chemokine CCL2. J Exp Med (2004) 1.43
Genome-wide expression profiling of five mouse models identifies similarities and differences with human psoriasis. PLoS One (2011) 1.41
Thymic stromal lymphopoietin: a new cytokine in asthma. Curr Opin Pharmacol (2008) 1.35
Alpha-galactosylceramide (KRN7000) suppression of chemical- and oncogene-dependent carcinogenesis. Proc Natl Acad Sci U S A (2003) 1.35
Activation of natural killer (NK) T cells during murine cytomegalovirus infection enhances the antiviral response mediated by NK cells. J Virol (2003) 1.35
Retinoic acid and polyriboinosinic:polyribocytidylic acid stimulate robust anti-tetanus antibody production while differentially regulating type 1/type 2 cytokines and lymphocyte populations. J Immunol (2005) 1.32
Selective activation, expansion, and monitoring of human iNKT cells with a monoclonal antibody specific for the TCR alpha-chain CDR3 loop. Eur J Immunol (2008) 1.32
Activation of NKT cells protects mice from tuberculosis. Infect Immun (2002) 1.31
The adaptor protein AP-3 is required for CD1d-mediated antigen presentation of glycosphingolipids and development of Valpha14i NKT cells. J Exp Med (2003) 1.31
Cytokines and the pathogenesis of non-alcoholic steatohepatitis. Gut (2005) 1.30
Glycolipid presentation to natural killer T cells differs in an organ-dependent fashion. Proc Natl Acad Sci U S A (2005) 1.29
Inhibition of glycolipid shedding rescues recognition of a CD1+ T cell lymphoma by natural killer T (NKT) cells. Proc Natl Acad Sci U S A (2002) 1.25
Natural killer T cells reactive to a single glycolipid exhibit a highly diverse T cell receptor beta repertoire and small clone size. Proc Natl Acad Sci U S A (2001) 1.22
Development of innate CD4+ alpha-chain variable gene segment 24 (Valpha24) natural killer T cells in the early human fetal thymus is regulated by IL-7. Proc Natl Acad Sci U S A (2004) 1.21
Glycolipid-activated NKT cells support the induction of persistent plasma cell responses and antibody titers. Eur J Immunol (2008) 1.18
Critical proinflammatory and anti-inflammatory functions of different subsets of CD1d-restricted natural killer T cells during Trypanosoma cruzi infection. Infect Immun (2005) 1.17
NKT cell-dependent leukemia eradication following stem cell mobilization with potent G-CSF analogs. J Clin Invest (2005) 1.16
Frequency and phenotype of circulating Valpha24/Vbeta11 double-positive natural killer T cells during hepatitis C virus infection. J Virol (2003) 1.16
Vitamin D regulation of immune function in the gut: why do T cells have vitamin D receptors? Mol Aspects Med (2011) 1.14
Yes T cells, but three different T cells (alphabeta, gammadelta and NK T cells), and also B-1 cells mediate contact sensitivity. Clin Exp Immunol (2001) 1.12
IFN-gamma-mediated negative feedback regulation of NKT-cell function by CD94/NKG2. Blood (2005) 1.12
Invariant and noninvariant natural killer T cells exert opposite regulatory functions on the immune response during murine schistosomiasis. Infect Immun (2007) 1.12
Beta-glucosylceramide: a novel method for enhancement of natural killer T lymphoycte plasticity in murine models of immune-mediated disorders. Gut (2007) 1.10
During Trypanosoma cruzi infection CD1d-restricted NK T cells limit parasitemia and augment the antibody response to a glycophosphoinositol-modified surface protein. Infect Immun (2002) 1.09
The anti-tetanus immune response of neonatal mice is augmented by retinoic acid combined with polyriboinosinic:polyribocytidylic acid. Proc Natl Acad Sci U S A (2005) 1.09
Identification and simian immunodeficiency virus infection of CD1d-restricted macaque natural killer T cells. J Virol (2003) 1.08
Regulatory T cells and natural killer T cells for modulation of GVHD following allogeneic hematopoietic cell transplantation. Blood (2013) 1.07
Deleting TCR alpha beta+ or CD4+ T lymphocytes leads to opposite effects on site-specific atherosclerosis in female apolipoprotein E-deficient mice. Am J Pathol (2004) 1.06
The role of hepatic invariant NKT cells in systemic/local inflammation and mortality during polymicrobial septic shock. J Immunol (2009) 1.04
The vitamin d receptor and T cell function. Front Immunol (2013) 1.03
Combined targeting of costimulatory (OX40) and coinhibitory (CTLA-4) pathways elicits potent effector T cells capable of driving robust antitumor immunity. Cancer Immunol Res (2013) 1.03
CD1d-restricted natural killer T cells are potent targets for human immunodeficiency virus infection. Immunology (2003) 1.01
Interferon-γ-secreting NK cells promote induction of dry eye disease. J Leukoc Biol (2011) 1.00
Role of innate immunity against human papillomavirus (HPV) infections and effect of adjuvants in promoting specific immune response. Viruses (2013) 0.99
Maturational alterations of peripheral T cell subsets and cytokine gene expression in 22q11.2 deletion syndrome. Clin Exp Immunol (2006) 0.99
Dysfunction of natural killer T cells in patients with active Mycobacterium tuberculosis infection. Infect Immun (2012) 0.98
Characterization of guinea-pig group 1 CD1 proteins. Immunology (2002) 0.97
Tim-3/galectin-9 regulate the homeostasis of hepatic NKT cells in a murine model of nonalcoholic fatty liver disease. J Immunol (2013) 0.97
PD-L1: PD-1 interaction contributes to the functional suppression of T-cell responses to human uveal melanoma cells in vitro. Invest Ophthalmol Vis Sci (2008) 0.96
Regulation of CCR5 expression and MIP-1alpha production in CD4+ T cells from patients with rheumatoid arthritis. Clin Exp Immunol (2003) 0.96
Secretion of IFN-gamma but not IL-17 by CD1d-restricted NKT cells enhances rejection of skin grafts expressing epithelial cell-derived antigen. J Immunol (2010) 0.96
Invariant NKT cells as initiators, licensors, and facilitators of the adaptive immune response. J Exp Med (2003) 0.96
Immune mechanisms in acetaminophen-induced acute liver failure. Hepatobiliary Surg Nutr (2014) 0.96
The split personality of NKT cells in malignancy, autoimmune and allergic disorders. Immunotherapy (2011) 0.95
NKT cells in the induced sputum of severe asthmatics. Mediators Inflamm (2006) 0.95
A unique lymphotoxin {alpha}beta-dependent pathway regulates thymic emigration of V{alpha}14 invariant natural killer T cells. Proc Natl Acad Sci U S A (2006) 0.95
Unifying model for molecular determinants of the preselection Vβ repertoire. Proc Natl Acad Sci U S A (2013) 0.95
Immunoregulatory mechanisms and CD4-CD8- (double negative) T cell subpopulations in human cutaneous leishmaniasis: a balancing act between protection and pathology. Int Immunopharmacol (2008) 0.95
Intrahepatic natural killer T cell populations are increased in human hepatic steatosis. World J Gastroenterol (2011) 0.94
Increased susceptibility of natural killer T-cell-deficient mice to acetaminophen-induced liver injury. Hepatology (2013) 0.94
Invariant Valpha14 chain NKT cells promote Plasmodium berghei circumsporozoite protein-specific gamma interferon- and tumor necrosis factor alpha-producing CD8+ T cells in the liver after poxvirus vaccination of mice. Infect Immun (2005) 0.92
Hierarchical and selective roles of galectins in hepatocarcinogenesis, liver fibrosis and inflammation of hepatocellular carcinoma. World J Gastroenterol (2013) 0.92
How do natural killer T cells help B cells? Expert Rev Vaccines (2009) 0.92
Increased mortality and dysregulated cytokine production in tumor necrosis factor receptor 1-deficient mice following systemic Klebsiella pneumoniae infection. Infect Immun (2003) 0.92
Natural killer T-cell characterization through gene expression profiling: an account of versatility bridging T helper type 1 (Th1), Th2 and Th17 immune responses. Immunology (2007) 0.91
CD4+ invariant natural killer T cells protect from murine GVHD lethality through expansion of donor CD4+CD25+FoxP3+ regulatory T cells. Blood (2014) 0.91
Salmonella enterica serovar Typhi live vector vaccines delivered intranasally elicit regional and systemic specific CD8+ major histocompatibility class I-restricted cytotoxic T lymphocytes. Infect Immun (2002) 0.91
gammadelta T cells regulate the early inflammatory response to bordetella pertussis infection in the murine respiratory tract. Infect Immun (2006) 0.90
Involvement of natural killer T cells in halothane-induced liver injury in mice. Biochem Pharmacol (2010) 0.90
Ocular immune privilege and ocular melanoma: parallel universes or immunological plagiarism? Front Immunol (2012) 0.90
T cell responses: naive to memory and everything in between. Adv Physiol Educ (2013) 0.89
Mice lacking natural killer T cells are more susceptible to metabolic alterations following high fat diet feeding. PLoS One (2014) 0.88
Synthetic glycolipid activators of natural killer T cells as immunotherapeutic agents. Clin Transl Immunology (2016) 0.88
Hepatic steatosis is associated with lower incidence of liver metastasis from colorectal cancer. Int J Colorectal Dis (2013) 0.88
CD161+ T (NT) cells exist predominantly in human intestinal epithelium as well as in liver. Clin Exp Immunol (2002) 0.88
Characterization of the immune cell repertoire in the normal fallopian tube. Int J Gynecol Pathol (2014) 0.88
Subcongenic analysis of genetic basis for impaired development of invariant NKT cells in NOD mice. Immunogenetics (2007) 0.87
The role of T lymphocytes in cancer patients undergoing immunotherapy with autologous dendritic cells. Clin Med Insights Oncol (2011) 0.87
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Involvement of tumor necrosis factor-related apoptosis-inducing ligand in surveillance of tumor metastasis by liver natural killer cells. Nat Med (2001) 2.74
The histone deacetylase inhibitor and chemotherapeutic agent suberoylanilide hydroxamic acid (SAHA) induces a cell-death pathway characterized by cleavage of Bid and production of reactive oxygen species. Proc Natl Acad Sci U S A (2001) 2.65
Extracellular adenosine triphosphate and adenosine in cancer. Oncogene (2010) 2.53
Mechanism of action of immunomodulatory drugs (IMiDS) in multiple myeloma. Leukemia (2009) 2.50
Perforin and interferon-gamma activities independently control tumor initiation, growth, and metastasis. Blood (2001) 2.45
Analysis of the apoptotic and therapeutic activities of histone deacetylase inhibitors by using a mouse model of B cell lymphoma. Proc Natl Acad Sci U S A (2007) 2.10
NKT cells are phenotypically and functionally diverse. Eur J Immunol (1999) 1.97
CD1d-restricted NKT cells: an interstrain comparison. J Immunol (2001) 1.88
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NKT cells and tumor immunity--a double-edged sword. Nat Immunol (2000) 1.53
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CD1-restricted T cells and tumor immunity. Curr Top Microbiol Immunol (2007) 1.45
Targeting death-inducing receptors in cancer therapy. Oncogene (2007) 1.42
Cytometric and functional analyses of NK and NKT cell deficiencies in NOD mice. Int Immunol (2001) 1.40
Clonal cytotoxic T cells are expanded in myeloma and reside in the CD8(+)CD57(+)CD28(-) compartment. Blood (2001) 1.37
Efficient nuclear targeting of granzyme B and the nuclear consequences of apoptosis induced by granzyme B and perforin are caspase-dependent, but cell death is caspase-independent. J Biol Chem (1998) 1.36
An essential role for tumor necrosis factor in natural killer cell-mediated tumor rejection in the peritoneum. J Exp Med (1998) 1.36
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Immunopurification of functional Asp-ase (natural killer cell granzyme B) using a monoclonal antibody. Biochem Biophys Res Commun (1993) 1.14
Flow cytometric study of T cell development in NOD mice reveals a deficiency in alphabetaTCR+CDR-CD8- thymocytes. J Autoimmun (1997) 1.12
Molecular mechanisms of natural killer cell activation in response to cellular stress. Cell Death Differ (2013) 1.11
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A role for P-glycoprotein in regulating cell death. Leuk Lymphoma (2000) 0.99
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Contribution of humoral immune responses to the antitumor effects mediated by anthracyclines. Cell Death Differ (2013) 0.95
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