S A Liebhaber

Author PubWeight™ 105.11‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Suppressor T cells. J Immunol 1972 3.92
2 Homology and concerted evolution at the alpha 1 and alpha 2 loci of human alpha-globin. Nature 1981 2.97
3 Identification of two KH domain proteins in the alpha-globin mRNP stability complex. EMBO J 1995 2.87
4 Cloning and complete nucleotide sequence of human 5'-alpha-globin gene. Proc Natl Acad Sci U S A 1980 2.62
5 Detection and characterization of a 3' untranslated region ribonucleoprotein complex associated with human alpha-globin mRNA stability. Mol Cell Biol 1995 2.36
6 beta zero thalassemia in Sardinia is caused by a nonsense mutation. J Clin Invest 1981 2.30
7 Substrate specificity of the dsRNA unwinding/modifying activity. EMBO J 1991 2.18
8 Erythroid cell-specific mRNA stability elements in the alpha 2-globin 3' nontranslated region. Mol Cell Biol 1995 2.04
9 Osteopathy and resistance to vitamin D toxicity in mice null for vitamin D binding protein. J Clin Invest 1999 2.02
10 Four highly stable eukaryotic mRNAs assemble 3' untranslated region RNA-protein complexes sharing cis and trans components. Proc Natl Acad Sci U S A 1997 1.97
11 Erythroid cell-specific determinants of alpha-globin mRNA stability. Mol Cell Biol 1994 1.96
12 The LIM/double zinc-finger motif functions as a protein dimerization domain. Proc Natl Acad Sci U S A 1994 1.94
13 Translationally associated helix-destabilizing activity in rabbit reticulocyte lysate. J Biol Chem 1984 1.85
14 Assembly of the alpha-globin mRNA stability complex reflects binary interaction between the pyrimidine-rich 3' untranslated region determinant and poly(C) binding protein alphaCP. Mol Cell Biol 1999 1.66
15 The human growth hormone gene is regulated by a multicomponent locus control region. Mol Cell Biol 1995 1.54
16 Optimized RNA targets of two closely related triple KH domain proteins, heterogeneous nuclear ribonucleoprotein K and alphaCP-2KL, suggest Distinct modes of RNA recognition. J Biol Chem 2001 1.53
17 Differentiation of the mRNA transcripts originating from the alpha 1- and alpha 2-globin loci in normals and alpha-thalassemics. J Clin Invest 1981 1.43
18 A native RNA secondary structure controls alternative splice-site selection and generates two human growth hormone isoforms. J Biol Chem 1992 1.43
19 Targeted recruitment of histone acetyltransferase activity to a locus control region. J Biol Chem 2000 1.40
20 Globin structural mutant alpha 125Leu leads to Pro is a novel cause of alpha-thalassaemia. Nature 1982 1.37
21 Patterns of histone acetylation suggest dual pathways for gene activation by a bifunctional locus control region. EMBO J 2000 1.28
22 Pit-1 binding sites at the somatotrope-specific DNase I hypersensitive sites I, II of the human growth hormone locus control region are essential for in vivo hGH-N gene activation. J Biol Chem 1999 1.27
23 Lethal alpha-thalassaemia created by gene targeting in mice and its genetic rescue. Nat Genet 1995 1.27
24 Human cysteine-rich protein. A member of the LIM/double-finger family displaying coordinate serum induction with c-myc. J Biol Chem 1992 1.26
25 A set of highly conserved RNA-binding proteins, alphaCP-1 and alphaCP-2, implicated in mRNA stabilization, are coexpressed from an intronless gene and its intron-containing paralog. J Biol Chem 1999 1.26
26 The human growth hormone gene cluster locus control region supports position-independent pituitary- and placenta-specific expression in the transgenic mouse. J Biol Chem 2000 1.25
27 Structural and evolutionary analysis of the two chimpanzee alpha-globin mRNAs. Nucleic Acids Res 1983 1.23
28 PERK-dependent regulation of IAP translation during ER stress. Oncogene 2008 1.23
29 Destabilization of messenger RNA/complementary DNA duplexes by the elongating 80 S ribosome. J Biol Chem 1986 1.18
30 Destabilization of human alpha-globin mRNA by translation anti-termination is controlled during erythroid differentiation and is paralleled by phased shortening of the poly(A) tail. J Biol Chem 1997 1.17
31 Identification of two novel mammalian genes establishes a subfamily of KH-domain RNA-binding proteins. Genomics 2000 1.13
32 DNase I-hypersensitive sites I and II of the human growth hormone locus control region are a major developmental activator of somatotrope gene expression. Proc Natl Acad Sci U S A 1998 1.13
33 The response of T cells to histocompatibility-2 antigens. Dose-response kinetics. J Exp Med 1972 1.11
34 Two distinct species of human growth hormone-variant mRNA in the human placenta predict the expression of novel growth hormone proteins. J Biol Chem 1988 1.08
35 The stability of human beta-globin mRNA is dependent on structural determinants positioned within its 3' untranslated region. Blood 1996 1.06
36 Human alpha-globin genes demonstrate autonomous developmental regulation in transgenic mice. Mol Cell Biol 1991 1.05
37 Differences in rRNA metabolism of primary and SV40-transformed human fibroblasts. Cell 1978 1.04
38 Sequence divergence in the 3' untranslated regions of human zeta- and alpha-globin mRNAs mediates a difference in their stabilities and contributes to efficient alpha-to-zeta gene development switching. Mol Cell Biol 1998 1.04
39 alpha-Thalassemia caused by an unstable alpha-globin mutant. J Clin Invest 1983 1.03
40 Developmental control and alternative splicing of the placentally expressed transcripts from the human growth hormone gene cluster. J Biol Chem 1992 1.02
41 Human alpha-globin gene expression. The dominant role of the alpha 2-locus in mRNA and protein synthesis. J Biol Chem 1986 1.02
42 Physical linkage of the human growth hormone gene cluster and the skeletal muscle sodium channel alpha-subunit gene (SCN4A) on chromosome 17. Genomics 1995 1.01
43 Physical linkage of the human growth hormone gene cluster and the CD79b (Ig beta/B29) gene. Genomics 1998 1.01
44 Different rates of mRNA translation balance the expression of the two human alpha-globin loci. J Biol Chem 1982 1.00
45 Complementary change in cis determinants and trans factors in the evolution of an mRNP stability complex. EMBO J 1996 1.00
46 Compensatory increase in alpha 1-globin gene expression in individuals heterozygous for the alpha-thalassemia-2 deletion. J Clin Invest 1985 1.00
47 Molecular basis for nondeletion alpha-thalassemia in American blacks. Alpha 2(116GAG----UAG). J Clin Invest 1987 0.96
48 Human embryonic zeta-globin chain expression in deletional alpha-thalassemias. Blood 1992 0.94
49 Reversal of lethal alpha- and beta-thalassemias in mice by expression of human embryonic globins. Blood 1998 0.94
50 Bidirectional effects of interaction between parental thymocytes and F1 spleen cells in the production of graft vs host splenomegaly. J Immunol 1972 0.93
51 Locus assignment of alpha-globin structural mutations by hybrid-selected translation. J Clin Invest 1985 0.93
52 The role of mRNA stability in the control of globin gene expression. Prog Nucleic Acid Res Mol Biol 1997 0.92
53 Human growth hormone gene and the highly homologous growth hormone variant gene display different splicing patterns. J Clin Invest 1988 0.92
54 A difference in the splicing patterns of the closely related normal and variant human growth hormone gene transcripts is determined by a minimal sequence divergence between two potential splice-acceptor sites. J Biol Chem 1990 0.90
55 A 3'-flanking NF-kappaB site mediates developmental silencing of the human zeta-globin gene. EMBO J 1999 0.90
56 Complex alternative splicing partially inactivates the human chorionic somatomammotropin-like (hCS-L) gene. J Biol Chem 1994 0.90
57 Dual pathways for ribonucleic acid turnover in WI-38 but not in I-cell human diploid fibroblasts. Mol Cell Biol 1981 0.89
58 Expression of a human growth hormone (hGH) receptor isoform is predicted by tissue-specific alternative splicing of exon 3 of the hGH receptor gene transcript. Mol Endocrinol 1992 0.89
59 An initiation codon mutation (AUG----GUG) of the human alpha 1-globin gene. Structural characterization and evidence for a mild thalassemic phenotype. J Clin Invest 1987 0.88
60 Molecular biology of the growth hormone-prolactin gene system. Vitam Horm 1995 0.87
61 Vitamin D-binding protein gene transcription is regulated by the relative abundance of hepatocyte nuclear factors 1alpha and 1beta. J Biol Chem 1998 0.87
62 Theta, zeta, and epsilon globin messenger RNAs are expressed in adults. Blood 1989 0.86
63 Significance of cell interactions in production of graft versus host splenomegaly. Yale J Biol Med 1972 0.86
64 Molecular basis for alpha-thalassemia associated with the structural mutant hemoglobin Suan-Dok (alpha 2 109leu----arg) Blood 1990 0.85
65 Translational profiles of alpha 1-, alpha 2-, and beta-globin messenger ribonucleic acids in human reticulocytes. J Clin Invest 1986 0.85
66 Beta thalassemia in Sardinia in the result of a nonsense mutation. Trans Assoc Am Physicians 1981 0.82
67 Hemoglobin I mutation encoded at both alpha-globin loci on the same chromosome: concerted evolution in the human genome. Science 1984 0.82
68 Alpha-thalassemia resulting from deletion of regulatory sequences far upstream of the alpha-globin structural genes. Blood 1991 0.82
69 Developmental switching of messenger RNA expression from the human alpha-globin cluster: fetal/adult pattern of theta-globin gene expression. Blood 1992 0.82
70 Human growth hormone-variant is a biologically active somatogen and lactogen. Endocrinology 1991 0.82
71 Analysis of the human cysteine-rich protein gene (CSRP), assignment to chromosome 1q24-1q32, and identification of an associated MspI polymorphism. Genomics 1992 0.82
72 Regulation of ribosomal ribonucleic acid levels in growing, 3H-arrested, and crisis-phase WI-38 human diploid fibroblasts. Biochemistry 1980 0.81
73 Human growth hormone variant produces insulin-like and lipolytic responses in rat adipose tissue. Endocrinology 1991 0.81
74 Human growth hormone-variant demonstrates a receptor binding profile distinct from that of normal pituitary growth hormone. J Biol Chem 1990 0.81
75 Double-stranded RNA triggers generalized translational arrest in Xenopus oocytes. Biochem Biophys Res Commun 1993 0.81
76 Physical and meiotic mapping of the region of human chromosome 4q11-q13 encompassing the vitamin D binding protein DBP/Gc-globulin and albumin multigene cluster. Genome Res 1999 0.81
77 Influence of duplexes 3' to the mRNA initiation codon on the efficiency of monosome formation. Biochemistry 1988 0.80
78 Developmental switch in the relative expression of the alpha 1- and alpha 2-globin genes in humans and in transgenic mice. Blood 1992 0.80
79 Binding of human growth hormone (GH)-variant (placental GH) to GH-binding proteins in human plasma. J Clin Endocrinol Metab 1991 0.79
80 Functional characterization of the alternatively spliced, placental human growth hormone receptor. J Biol Chem 1993 0.79
81 Alternative splice site selection in the human growth hormone gene transcript and synthesis of the 20 kDa isoform: role of higher order transcript structure. Acta Paediatr Suppl 1994 0.78
82 Synthesis of growth hormone-prolactin chimeric proteins and processing mutants by the exchange and deletion of genomic exons. J Biol Chem 1986 0.78
83 Molecular pathology of alpha-thalassemia. Birth Defects Orig Artic Ser 1982 0.78
84 High-level production of human alpha- and beta-globins in insect cells. Protein Expr Purif 1992 0.77
85 Glycosylated human growth hormone variant. Endocrinology 1989 0.76
86 The human growth hormone locus control region mediates long-distance transcriptional activation independent of nuclear matrix attachment regions. Nucleic Acids Res 2001 0.76
87 Identification of a splice-site mutation in the human growth hormone-variant gene. Am J Hum Genet 1991 0.76
88 Hematologic improvement following splenectomy for hemoglobin-H disease. West J Med 1982 0.75
89 Locus assignment of two alpha-globin structural mutants from the Caribbean basin: alpha Fort de France (alpha 45 Arg) and alpha Spanish Town (alpha 27 Val). Blood 1989 0.75
90 Nucleic Acid degradation. Science 1993 0.75
91 Dialysis addition of trehalose/glycerol cryoprotectant allows recovery of cryopreserved mouse spermatozoa with satisfactory fertilizing ability as assessed by yield of live young. J Androl 2001 0.75
92 Update on hemoglobinopathies. Dis Mon 1983 0.75
93 Alteration in the receptor binding specificity of human growth hormone by genomic exon exchange. Mol Endocrinol 1990 0.75
94 Full developmental silencing of the embryonic zeta-globin gene reflects instability of its mRNA. Ann N Y Acad Sci 1998 0.75
95 Opposite responses of rabbit and human globin mRNAs to translational inhibition by cap analogues. Biochemistry 1987 0.75
96 Tritium-arrested human diploid fibroblasts maintain balanced RNA and protein metabolism. Exp Cell Res 1978 0.75