Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
1
|
Suppressor T cells.
|
J Immunol
|
1972
|
3.92
|
2
|
Homology and concerted evolution at the alpha 1 and alpha 2 loci of human alpha-globin.
|
Nature
|
1981
|
2.97
|
3
|
Identification of two KH domain proteins in the alpha-globin mRNP stability complex.
|
EMBO J
|
1995
|
2.87
|
4
|
Cloning and complete nucleotide sequence of human 5'-alpha-globin gene.
|
Proc Natl Acad Sci U S A
|
1980
|
2.62
|
5
|
Detection and characterization of a 3' untranslated region ribonucleoprotein complex associated with human alpha-globin mRNA stability.
|
Mol Cell Biol
|
1995
|
2.36
|
6
|
beta zero thalassemia in Sardinia is caused by a nonsense mutation.
|
J Clin Invest
|
1981
|
2.30
|
7
|
Substrate specificity of the dsRNA unwinding/modifying activity.
|
EMBO J
|
1991
|
2.18
|
8
|
Erythroid cell-specific mRNA stability elements in the alpha 2-globin 3' nontranslated region.
|
Mol Cell Biol
|
1995
|
2.04
|
9
|
Osteopathy and resistance to vitamin D toxicity in mice null for vitamin D binding protein.
|
J Clin Invest
|
1999
|
2.02
|
10
|
Four highly stable eukaryotic mRNAs assemble 3' untranslated region RNA-protein complexes sharing cis and trans components.
|
Proc Natl Acad Sci U S A
|
1997
|
1.97
|
11
|
Erythroid cell-specific determinants of alpha-globin mRNA stability.
|
Mol Cell Biol
|
1994
|
1.96
|
12
|
The LIM/double zinc-finger motif functions as a protein dimerization domain.
|
Proc Natl Acad Sci U S A
|
1994
|
1.94
|
13
|
Translationally associated helix-destabilizing activity in rabbit reticulocyte lysate.
|
J Biol Chem
|
1984
|
1.85
|
14
|
Assembly of the alpha-globin mRNA stability complex reflects binary interaction between the pyrimidine-rich 3' untranslated region determinant and poly(C) binding protein alphaCP.
|
Mol Cell Biol
|
1999
|
1.66
|
15
|
The human growth hormone gene is regulated by a multicomponent locus control region.
|
Mol Cell Biol
|
1995
|
1.54
|
16
|
Optimized RNA targets of two closely related triple KH domain proteins, heterogeneous nuclear ribonucleoprotein K and alphaCP-2KL, suggest Distinct modes of RNA recognition.
|
J Biol Chem
|
2001
|
1.53
|
17
|
Differentiation of the mRNA transcripts originating from the alpha 1- and alpha 2-globin loci in normals and alpha-thalassemics.
|
J Clin Invest
|
1981
|
1.43
|
18
|
A native RNA secondary structure controls alternative splice-site selection and generates two human growth hormone isoforms.
|
J Biol Chem
|
1992
|
1.43
|
19
|
Targeted recruitment of histone acetyltransferase activity to a locus control region.
|
J Biol Chem
|
2000
|
1.40
|
20
|
Globin structural mutant alpha 125Leu leads to Pro is a novel cause of alpha-thalassaemia.
|
Nature
|
1982
|
1.37
|
21
|
Patterns of histone acetylation suggest dual pathways for gene activation by a bifunctional locus control region.
|
EMBO J
|
2000
|
1.28
|
22
|
Pit-1 binding sites at the somatotrope-specific DNase I hypersensitive sites I, II of the human growth hormone locus control region are essential for in vivo hGH-N gene activation.
|
J Biol Chem
|
1999
|
1.27
|
23
|
Lethal alpha-thalassaemia created by gene targeting in mice and its genetic rescue.
|
Nat Genet
|
1995
|
1.27
|
24
|
Human cysteine-rich protein. A member of the LIM/double-finger family displaying coordinate serum induction with c-myc.
|
J Biol Chem
|
1992
|
1.26
|
25
|
A set of highly conserved RNA-binding proteins, alphaCP-1 and alphaCP-2, implicated in mRNA stabilization, are coexpressed from an intronless gene and its intron-containing paralog.
|
J Biol Chem
|
1999
|
1.26
|
26
|
The human growth hormone gene cluster locus control region supports position-independent pituitary- and placenta-specific expression in the transgenic mouse.
|
J Biol Chem
|
2000
|
1.25
|
27
|
Structural and evolutionary analysis of the two chimpanzee alpha-globin mRNAs.
|
Nucleic Acids Res
|
1983
|
1.23
|
28
|
PERK-dependent regulation of IAP translation during ER stress.
|
Oncogene
|
2008
|
1.23
|
29
|
Destabilization of messenger RNA/complementary DNA duplexes by the elongating 80 S ribosome.
|
J Biol Chem
|
1986
|
1.18
|
30
|
Destabilization of human alpha-globin mRNA by translation anti-termination is controlled during erythroid differentiation and is paralleled by phased shortening of the poly(A) tail.
|
J Biol Chem
|
1997
|
1.17
|
31
|
Identification of two novel mammalian genes establishes a subfamily of KH-domain RNA-binding proteins.
|
Genomics
|
2000
|
1.13
|
32
|
DNase I-hypersensitive sites I and II of the human growth hormone locus control region are a major developmental activator of somatotrope gene expression.
|
Proc Natl Acad Sci U S A
|
1998
|
1.13
|
33
|
The response of T cells to histocompatibility-2 antigens. Dose-response kinetics.
|
J Exp Med
|
1972
|
1.11
|
34
|
Two distinct species of human growth hormone-variant mRNA in the human placenta predict the expression of novel growth hormone proteins.
|
J Biol Chem
|
1988
|
1.08
|
35
|
The stability of human beta-globin mRNA is dependent on structural determinants positioned within its 3' untranslated region.
|
Blood
|
1996
|
1.06
|
36
|
Human alpha-globin genes demonstrate autonomous developmental regulation in transgenic mice.
|
Mol Cell Biol
|
1991
|
1.05
|
37
|
Differences in rRNA metabolism of primary and SV40-transformed human fibroblasts.
|
Cell
|
1978
|
1.04
|
38
|
Sequence divergence in the 3' untranslated regions of human zeta- and alpha-globin mRNAs mediates a difference in their stabilities and contributes to efficient alpha-to-zeta gene development switching.
|
Mol Cell Biol
|
1998
|
1.04
|
39
|
alpha-Thalassemia caused by an unstable alpha-globin mutant.
|
J Clin Invest
|
1983
|
1.03
|
40
|
Developmental control and alternative splicing of the placentally expressed transcripts from the human growth hormone gene cluster.
|
J Biol Chem
|
1992
|
1.02
|
41
|
Human alpha-globin gene expression. The dominant role of the alpha 2-locus in mRNA and protein synthesis.
|
J Biol Chem
|
1986
|
1.02
|
42
|
Physical linkage of the human growth hormone gene cluster and the skeletal muscle sodium channel alpha-subunit gene (SCN4A) on chromosome 17.
|
Genomics
|
1995
|
1.01
|
43
|
Physical linkage of the human growth hormone gene cluster and the CD79b (Ig beta/B29) gene.
|
Genomics
|
1998
|
1.01
|
44
|
Different rates of mRNA translation balance the expression of the two human alpha-globin loci.
|
J Biol Chem
|
1982
|
1.00
|
45
|
Complementary change in cis determinants and trans factors in the evolution of an mRNP stability complex.
|
EMBO J
|
1996
|
1.00
|
46
|
Compensatory increase in alpha 1-globin gene expression in individuals heterozygous for the alpha-thalassemia-2 deletion.
|
J Clin Invest
|
1985
|
1.00
|
47
|
Molecular basis for nondeletion alpha-thalassemia in American blacks. Alpha 2(116GAG----UAG).
|
J Clin Invest
|
1987
|
0.96
|
48
|
Human embryonic zeta-globin chain expression in deletional alpha-thalassemias.
|
Blood
|
1992
|
0.94
|
49
|
Reversal of lethal alpha- and beta-thalassemias in mice by expression of human embryonic globins.
|
Blood
|
1998
|
0.94
|
50
|
Bidirectional effects of interaction between parental thymocytes and F1 spleen cells in the production of graft vs host splenomegaly.
|
J Immunol
|
1972
|
0.93
|
51
|
Locus assignment of alpha-globin structural mutations by hybrid-selected translation.
|
J Clin Invest
|
1985
|
0.93
|
52
|
The role of mRNA stability in the control of globin gene expression.
|
Prog Nucleic Acid Res Mol Biol
|
1997
|
0.92
|
53
|
Human growth hormone gene and the highly homologous growth hormone variant gene display different splicing patterns.
|
J Clin Invest
|
1988
|
0.92
|
54
|
A difference in the splicing patterns of the closely related normal and variant human growth hormone gene transcripts is determined by a minimal sequence divergence between two potential splice-acceptor sites.
|
J Biol Chem
|
1990
|
0.90
|
55
|
A 3'-flanking NF-kappaB site mediates developmental silencing of the human zeta-globin gene.
|
EMBO J
|
1999
|
0.90
|
56
|
Complex alternative splicing partially inactivates the human chorionic somatomammotropin-like (hCS-L) gene.
|
J Biol Chem
|
1994
|
0.90
|
57
|
Dual pathways for ribonucleic acid turnover in WI-38 but not in I-cell human diploid fibroblasts.
|
Mol Cell Biol
|
1981
|
0.89
|
58
|
Expression of a human growth hormone (hGH) receptor isoform is predicted by tissue-specific alternative splicing of exon 3 of the hGH receptor gene transcript.
|
Mol Endocrinol
|
1992
|
0.89
|
59
|
An initiation codon mutation (AUG----GUG) of the human alpha 1-globin gene. Structural characterization and evidence for a mild thalassemic phenotype.
|
J Clin Invest
|
1987
|
0.88
|
60
|
Molecular biology of the growth hormone-prolactin gene system.
|
Vitam Horm
|
1995
|
0.87
|
61
|
Vitamin D-binding protein gene transcription is regulated by the relative abundance of hepatocyte nuclear factors 1alpha and 1beta.
|
J Biol Chem
|
1998
|
0.87
|
62
|
Theta, zeta, and epsilon globin messenger RNAs are expressed in adults.
|
Blood
|
1989
|
0.86
|
63
|
Significance of cell interactions in production of graft versus host splenomegaly.
|
Yale J Biol Med
|
1972
|
0.86
|
64
|
Molecular basis for alpha-thalassemia associated with the structural mutant hemoglobin Suan-Dok (alpha 2 109leu----arg)
|
Blood
|
1990
|
0.85
|
65
|
Translational profiles of alpha 1-, alpha 2-, and beta-globin messenger ribonucleic acids in human reticulocytes.
|
J Clin Invest
|
1986
|
0.85
|
66
|
Beta thalassemia in Sardinia in the result of a nonsense mutation.
|
Trans Assoc Am Physicians
|
1981
|
0.82
|
67
|
Hemoglobin I mutation encoded at both alpha-globin loci on the same chromosome: concerted evolution in the human genome.
|
Science
|
1984
|
0.82
|
68
|
Alpha-thalassemia resulting from deletion of regulatory sequences far upstream of the alpha-globin structural genes.
|
Blood
|
1991
|
0.82
|
69
|
Developmental switching of messenger RNA expression from the human alpha-globin cluster: fetal/adult pattern of theta-globin gene expression.
|
Blood
|
1992
|
0.82
|
70
|
Human growth hormone-variant is a biologically active somatogen and lactogen.
|
Endocrinology
|
1991
|
0.82
|
71
|
Analysis of the human cysteine-rich protein gene (CSRP), assignment to chromosome 1q24-1q32, and identification of an associated MspI polymorphism.
|
Genomics
|
1992
|
0.82
|
72
|
Regulation of ribosomal ribonucleic acid levels in growing, 3H-arrested, and crisis-phase WI-38 human diploid fibroblasts.
|
Biochemistry
|
1980
|
0.81
|
73
|
Human growth hormone variant produces insulin-like and lipolytic responses in rat adipose tissue.
|
Endocrinology
|
1991
|
0.81
|
74
|
Human growth hormone-variant demonstrates a receptor binding profile distinct from that of normal pituitary growth hormone.
|
J Biol Chem
|
1990
|
0.81
|
75
|
Double-stranded RNA triggers generalized translational arrest in Xenopus oocytes.
|
Biochem Biophys Res Commun
|
1993
|
0.81
|
76
|
Physical and meiotic mapping of the region of human chromosome 4q11-q13 encompassing the vitamin D binding protein DBP/Gc-globulin and albumin multigene cluster.
|
Genome Res
|
1999
|
0.81
|
77
|
Influence of duplexes 3' to the mRNA initiation codon on the efficiency of monosome formation.
|
Biochemistry
|
1988
|
0.80
|
78
|
Developmental switch in the relative expression of the alpha 1- and alpha 2-globin genes in humans and in transgenic mice.
|
Blood
|
1992
|
0.80
|
79
|
Binding of human growth hormone (GH)-variant (placental GH) to GH-binding proteins in human plasma.
|
J Clin Endocrinol Metab
|
1991
|
0.79
|
80
|
Functional characterization of the alternatively spliced, placental human growth hormone receptor.
|
J Biol Chem
|
1993
|
0.79
|
81
|
Alternative splice site selection in the human growth hormone gene transcript and synthesis of the 20 kDa isoform: role of higher order transcript structure.
|
Acta Paediatr Suppl
|
1994
|
0.78
|
82
|
Synthesis of growth hormone-prolactin chimeric proteins and processing mutants by the exchange and deletion of genomic exons.
|
J Biol Chem
|
1986
|
0.78
|
83
|
Molecular pathology of alpha-thalassemia.
|
Birth Defects Orig Artic Ser
|
1982
|
0.78
|
84
|
High-level production of human alpha- and beta-globins in insect cells.
|
Protein Expr Purif
|
1992
|
0.77
|
85
|
Glycosylated human growth hormone variant.
|
Endocrinology
|
1989
|
0.76
|
86
|
The human growth hormone locus control region mediates long-distance transcriptional activation independent of nuclear matrix attachment regions.
|
Nucleic Acids Res
|
2001
|
0.76
|
87
|
Identification of a splice-site mutation in the human growth hormone-variant gene.
|
Am J Hum Genet
|
1991
|
0.76
|
88
|
Hematologic improvement following splenectomy for hemoglobin-H disease.
|
West J Med
|
1982
|
0.75
|
89
|
Locus assignment of two alpha-globin structural mutants from the Caribbean basin: alpha Fort de France (alpha 45 Arg) and alpha Spanish Town (alpha 27 Val).
|
Blood
|
1989
|
0.75
|
90
|
Nucleic Acid degradation.
|
Science
|
1993
|
0.75
|
91
|
Dialysis addition of trehalose/glycerol cryoprotectant allows recovery of cryopreserved mouse spermatozoa with satisfactory fertilizing ability as assessed by yield of live young.
|
J Androl
|
2001
|
0.75
|
92
|
Update on hemoglobinopathies.
|
Dis Mon
|
1983
|
0.75
|
93
|
Alteration in the receptor binding specificity of human growth hormone by genomic exon exchange.
|
Mol Endocrinol
|
1990
|
0.75
|
94
|
Full developmental silencing of the embryonic zeta-globin gene reflects instability of its mRNA.
|
Ann N Y Acad Sci
|
1998
|
0.75
|
95
|
Opposite responses of rabbit and human globin mRNAs to translational inhibition by cap analogues.
|
Biochemistry
|
1987
|
0.75
|
96
|
Tritium-arrested human diploid fibroblasts maintain balanced RNA and protein metabolism.
|
Exp Cell Res
|
1978
|
0.75
|