PubRank

F M Watt

Author PubWeight™ 155.88‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Separation of human epidermal stem cells from transit amplifying cells on the basis of differences in integrin function and expression. Cell 1993 5.86
2 Stem cell patterning and fate in human epidermis. Cell 1995 5.22
3 Regulation of development and differentiation by the extracellular matrix. Development 1993 4.13
4 The spatial relationship between stem cells and their progeny in the basal layer of human epidermis: a new view based on whole-mount labelling and lineage analysis. Development 1999 3.31
5 c-Myc activation in transgenic mouse epidermis results in mobilization of stem cells and differentiation of their progeny. Curr Biol 2001 3.22
6 Fibronectin inhibits the terminal differentiation of human keratinocytes. Nature 1989 2.77
7 Stimulation of human epidermal differentiation by delta-notch signalling at the boundaries of stem-cell clusters. Curr Biol 2000 2.58
8 Stem cells: the generation and maintenance of cellular diversity. Development 1989 2.54
9 Stratification and terminal differentiation of cultured epidermal cells. Nature 1982 2.44
10 c-Myc promotes differentiation of human epidermal stem cells. Genes Dev 1997 2.37
11 Suprabasal integrin expression in the epidermis of transgenic mice results in developmental defects and a phenotype resembling psoriasis. Cell 1995 2.24
12 The EGF receptor provides an essential survival signal for SOS-dependent skin tumor development. Cell 2000 2.22
13 Changes in keratinocyte adhesion during terminal differentiation: reduction in fibronectin binding precedes alpha 5 beta 1 integrin loss from the cell surface. Cell 1990 2.19
14 Involucrin synthesis is correlated with cell size in human epidermal cultures. J Cell Biol 1981 2.14
15 Signaling via beta1 integrins and mitogen-activated protein kinase determines human epidermal stem cell fate in vitro. Proc Natl Acad Sci U S A 1999 2.06
16 Evidence that cadherins play a role in the downregulation of integrin expression that occurs during keratinocyte terminal differentiation. J Cell Biol 1994 2.05
17 Calcium-induced reorganization of desmosomal components in cultured human keratinocytes. J Cell Biol 1984 2.00
18 Selective migration of terminally differentiating cells from the basal layer of cultured human epidermis. J Cell Biol 1984 1.93
19 Desmosomal glycoprotein DGI, a component of intercellular desmosome junctions, is related to the cadherin family of cell adhesion molecules. Proc Natl Acad Sci U S A 1991 1.91
20 beta-catenin signalling modulates proliferative potential of human epidermal keratinocytes independently of intercellular adhesion. Development 1999 1.89
21 Expression of a dominant negative cadherin mutant inhibits proliferation and stimulates terminal differentiation of human epidermal keratinocytes. J Cell Sci 1996 1.74
22 Proliferative heterogeneity in the human prostate: evidence for epithelial stem cells. Lab Invest 2000 1.66
23 Antinuclear autoantibodies and lupus nephritis in transgenic mice expressing interferon gamma in the epidermis. J Exp Med 1997 1.63
24 DNA amplification is rare in normal human cells. Proc Natl Acad Sci U S A 1990 1.63
25 Aberrant integrin expression during epidermal wound healing and in psoriatic epidermis. J Clin Invest 1992 1.58
26 Involucrin and other markers of keratinocyte terminal differentiation. J Invest Dermatol 1983 1.58
27 Epithelial cell differentiation pathways in the human prostate: identification of intermediate phenotypes by keratin expression. J Histochem Cytochem 2001 1.50
28 Periplakin, a novel component of cornified envelopes and desmosomes that belongs to the plakin family and forms complexes with envoplakin. J Cell Biol 1997 1.50
29 Regulation of cell surface beta 1 integrin levels during keratinocyte terminal differentiation. J Cell Biol 1995 1.48
30 Expression of beta 1, beta 3, beta 4, and beta 5 integrins by human epidermal keratinocytes and non-differentiating keratinocytes. J Cell Biol 1991 1.42
31 Measurement of the rate of epidermal terminal differentiation: expression of involucrin by S-phase keratinocytes in culture and in psoriatic plaques. J Invest Dermatol 1987 1.42
32 Two subpopulations of differentiated chondrocytes identified with a monoclonal antibody to keratan sulfate. J Cell Biol 1985 1.41
33 Integrin expression during human epidermal development in vivo and in vitro. Development 1991 1.41
34 The plakin family: versatile organizers of cytoskeletal architecture. Curr Opin Genet Dev 1997 1.39
35 Asymmetric stem-cell divisions define the architecture of human oesophageal epithelium. Curr Biol 2000 1.39
36 Effect of growth environment on spatial expression of involucrin by human epidermal keratinocytes. Arch Dermatol Res 1987 1.36
37 Envoplakin, a novel precursor of the cornified envelope that has homology to desmoplakin. J Cell Biol 1996 1.35
38 Indian hedgehog and beta-catenin signaling: role in the sebaceous lineage of normal and neoplastic mammalian epidermis. Proc Natl Acad Sci U S A 2003 1.33
39 A role for mitogen-activated protein kinase activation by integrins in the pathogenesis of psoriasis. J Clin Invest 2001 1.31
40 Influence of beta1 integrins on epidermal squamous cell carcinoma formation in a transgenic mouse model: alpha3beta1, but not alpha2beta1, suppresses malignant conversion. Cancer Res 2001 1.28
41 Regulation by vitamin A of envelope cross-linking in cultured keratinocytes derived from different human epithelia. Mol Cell Biol 1982 1.27
42 beta1 integrins regulate keratinocyte adhesion and differentiation by distinct mechanisms. Mol Biol Cell 2000 1.26
43 Transgenic mice expressing IFN-gamma in the epidermis have eczema, hair hypopigmentation, and hair loss. J Invest Dermatol 1997 1.24
44 Analysis of cultured keratinocytes from a transgenic mouse model of psoriasis: effects of suprabasal integrin expression on keratinocyte adhesion, proliferation and terminal differentiation. Exp Dermatol 1999 1.24
45 Subcellular distribution of envoplakin and periplakin: insights into their role as precursors of the epidermal cornified envelope. J Cell Biol 2000 1.23
46 Changes in the expression of alpha v integrins in oral squamous cell carcinomas. J Oral Pathol Med 1997 1.21
47 Functional significance of CD9 association with beta 1 integrins in human epidermal keratinocytes. Cell Adhes Commun 1996 1.20
48 Transcriptional and post-translational regulation of beta 1 integrin expression during keratinocyte terminal differentiation. J Biol Chem 1992 1.19
49 Differentiation of embryonal stem cells into keratinocytes: comparison of wild-type and beta 1 integrin-deficient cells. Dev Biol 1996 1.17
50 Calcium-induced changes in distribution and solubility of cadherins, integrins and their associated cytoplasmic proteins in human keratinocytes. Cell Adhes Commun 1995 1.15
51 Evidence that apoptosis and terminal differentiation of epidermal keratinocytes are distinct processes. Exp Dermatol 1999 1.14
52 Changes in expression of members of the fos and jun families and myc network during terminal differentiation of human keratinocytes. Oncogene 1995 1.13
53 Biochemical specificity of Xenopus notochord. Differentiation 1985 1.13
54 Production of scatter factor by ndk, a strain of epithelial cells, and inhibition of scatter factor activity by suramin. J Cell Sci 1991 1.12
55 Optimised retroviral infection of human epidermal keratinocytes: long-term expression of transduced integrin gene following grafting on to SCID mice. Gene Ther 1998 1.11
56 Towards gene therapy for haemophilia B using primary human keratinocytes. Nat Genet 1993 1.10
57 Comparison of integrin, cadherin, and catenin expression in squamous cell carcinomas of the oral cavity. J Pathol 1998 1.10
58 Characterisation of eight monoclonal antibodies to involucrin. Hybridoma 1992 1.03
59 Gene targeting of envoplakin, a cytoskeletal linker protein and precursor of the epidermal cornified envelope. Mol Cell Biol 2001 1.01
60 Comparison of integrin expression and terminal differentiation capacity in cell lines derived from oral squamous cell carcinomas. Carcinogenesis 1993 1.01
61 Dermal fibroblast-derived growth factors restore the ability of beta(1) integrin-deficient embryonal stem cells to differentiate into keratinocytes. Dev Biol 2001 1.01
62 Integrin expression in normal, hyperplastic, dysplastic, and malignant oral epithelium. J Pathol 1993 1.00
63 Expression of E-cadherin, P-cadherin and involucrin by normal and neoplastic keratinocytes in culture. Carcinogenesis 1991 1.00
64 p19ARF-independent induction of p53 and cell cycle arrest by Raf in murine keratinocytes. EMBO Rep 2001 0.98
65 Upregulation of CD26 expression in epithelial cells and stromal cells during wound-induced skin tumour formation. Oncogene 2011 0.98
66 Biosynthesis of EGF receptor, transferrin receptor and colligin by cultured human keratinocytes and the effect of retinoic acid. Exp Cell Res 1985 0.97
67 Calcium-induced changes in cytoskeleton and motility of cultured human keratinocytes. Exp Cell Res 1987 0.97
68 Influence of cytochalasin D-induced changes in cell shape on proteoglycan synthesis by cultured articular chondrocytes. Exp Cell Res 1988 0.96
69 Delta regulates keratinocyte spreading and motility independently of differentiation. Mech Dev 2001 0.96
70 Expression of involucrin in normal, hyperproliferative and neoplastic mouse keratinocytes. Exp Dermatol 2000 0.95
71 The epidermal stem cell compartment: variation in expression levels of E-cadherin and catenins within the basal layer of human epidermis. J Histochem Cytochem 1997 0.95
72 Structure and regulation of the envoplakin gene. J Biol Chem 2000 0.94
73 Patterns of junctional communication in animal tissues. Ciba Found Symp 1987 0.93
74 CD44 is the major peanut lectin-binding glycoprotein of human epidermal keratinocytes and plays a role in intercellular adhesion. J Cell Sci 1995 0.93
75 An unusual strain of human keratinocytes which do not stratify or undergo terminal differentiation in culture. J Cell Biol 1988 0.93
76 Immunoelectron microscopic analysis of cornified cell envelope formation in normal and psoriatic epidermis. J Histochem Cytochem 1996 0.93
77 Microtubule-organizing centres in mammalian cells in culture. J Cell Sci 1980 0.93
78 Restoration of alpha v beta 5 integrin expression in neoplastic keratinocytes results in increased capacity for terminal differentiation and suppression of anchorage-independent growth. Oncogene 1996 0.92
79 Evidence against a major role for integrins in calcium-dependent intercellular adhesion of epidermal keratinocytes. Cell Adhes Commun 1993 0.92
80 Functional down-regulation of alpha 5 beta 1 integrin in keratinocytes is reversible but commitment to terminal differentiation is not. J Cell Sci 1993 0.92
81 Heterogeneous expression of keratin, involucrin, and extracellular matrix among subpopulations of a poorly differentiated human cervical carcinoma: possible relationships to patterns of invasion. Cancer Res 1989 0.91
82 Calcium-induced intercellular adhesion of keratinocytes does not involve accumulation of beta 1 integrins at cell-cell contacts and does not involve changes in the levels or phosphorylation of catenins. Cell Adhes Commun 1998 0.91
83 Decreased expression of fibronectin and the alpha 5 beta 1 integrin during terminal differentiation of human keratinocytes. J Cell Sci 1991 0.91
84 The alpha2 and alpha5 integrin genes: identification of transcription factors that regulate promoter activity in epidermal keratinocytes. FEBS Lett 2000 0.91
85 Correlation between hyperproliferation and suprabasal integrin expression in human epidermis reconstituted in culture. Exp Dermatol 1997 0.89
86 Altered expression of CD44 isoforms in squamous-cell carcinomas and cell lines derived from them. Int J Cancer 1996 0.89
87 A model for in vitro studies of epidermal homeostasis: proliferation and involucrin synthesis by cultured human keratinocytes during recovery after stripping off the suprabasal layers. J Invest Dermatol 1988 0.89
88 Two strains of human keratinocytes transfected with HPV16 DNA: comparison with the normal parental cells. Carcinogenesis 1991 0.89
89 Envoplakin, a possible candidate gene for focal NEPPK/esophageal cancer (TOC): the integration of genetic and physical maps of the TOC region on 17q25. Genomics 1999 0.88
90 A central role for alpha beta T cells in the pathogenesis of murine lupus. J Immunol 1999 0.88
91 Patterns of junctional communication in skin: studies on cultured keratinocytes. Exp Cell Res 1987 0.88
92 Subpopulations of chondrocytes from different zones of pig articular cartilage. Isolation, growth and proteoglycan synthesis in culture. J Cell Sci 1990 0.87
93 Loss of alpha 6 and beta 4 integrin subunits coincides with loss of basement membrane components in oral squamous cell carcinomas. J Pathol 1993 0.87
94 Role of integrins in mouse eyelid development: studies in normal embryos and embryos in which there is a failure of eyelid fusion. Mech Dev 1998 0.86
95 The peanut lectin-binding glycoproteins of human epidermal keratinocytes. Exp Cell Res 1988 0.86
96 Changes in the abundance and distribution of actin and associated proteins during terminal differentiation of human epidermal keratinocytes. J Cell Sci 1991 0.86
97 Keratinocyte cultures: an experimental model for studying how proliferation and terminal differentiation are co-ordinated in the epidermis. J Cell Sci 1988 0.85
98 Microtubule-organizing centres in binucleate cells and homosynkaryons. J Cell Sci 1980 0.85
99 Lack of keratan sulphate in the human notochord. J Anat 1988 0.84
100 Changes in the distribution of actin-associated proteins during epidermal wound healing. J Invest Dermatol 1993 0.84
101 Envoplakin and periplakin are components of the paraneoplastic pemphigus antigen complex. J Invest Dermatol 1998 0.84
102 Integrin expression and function in HPV 16-immortalised human keratinocytes in the presence or absence of v-Ha-ras. Comparison with cervical intraepithelial neoplasia. Oncogene 1994 0.84
103 PA-FABP, a novel marker of human epidermal transit amplifying cells revealed by 2D protein gel electrophoresis and cDNA array hybridisation. FEBS Lett 2000 0.83
104 Immunolocalization of keratan sulphate in the human embryonic cornea and other human foetal organs. J Cell Sci 1986 0.82
105 The distribution of actin cables and microtubules in hybrids between malignant and non-malignant cells, and in tumours derived from them. J Cell Sci 1978 0.82
106 The 5' noncoding region of the mouse involucrin gene: comparison with the human gene and genes encoding other cornified envelope precursors. Mamm Genome 1995 0.82
107 Lack of intrinsic polarity in the ligand-binding ability of keratinocyte beta1 integrins. Exp Dermatol 1998 0.82
108 Transfection of beta 4 integrin subunit into a neoplastic keratinocyte line fails to restore terminal differentiation capacity or influence proliferation. Cell Adhes Commun 1996 0.82
109 Cutting edge: amelioration of kidney disease in a transgenic mouse model of lupus nephritis by administration of the caspase inhibitor carbobenzoxy-valyl-alanyl-aspartyl-(beta-o-methyl)-fluoromethylketone. J Immunol 2001 0.82
110 Paraneoplastic pemphigus sera react strongly with multiple epitopes on the various regions of envoplakin and periplakin, except for the c-terminal homologous domain of periplakin. J Invest Dermatol 2001 0.81
111 Chromosomal localisation of the human envoplakin gene (EVPL) to the region of the tylosis oesophageal cancer gene (TOCG) on 17q25. Genomics 1996 0.80
112 The epidermal keratinocyte. Bioessays 1988 0.79
113 Integrin expression by human epidermal keratinocytes can be modulated by interferon-gamma, transforming growth factor-beta, tumor necrosis factor-alpha, and culture on a dermal equivalent. J Invest Dermatol 1995 0.79
114 Adhesion of human epidermal keratinocytes to laminin. Cell Adhes Commun 1994 0.79
115 The periplakin gene maps to 16p13.3 in human and 16A-B1 in mouse. Genomics 1998 0.77
116 Changes in type I keratin expression associated with HPV16 transformation of human epidermal keratinocytes. Epithelial Cell Biol 1992 0.77
117 beta1B integrin subunit contains a double lysine motif that can cause accumulation within the endoplasmic reticulum. J Cell Biochem 2000 0.76
118 Identification of an 80kD protein associated with the alpha 3 beta 1 integrin as a proteolytic fragment of the alpha 3 subunit: studies with human keratinocytes. Cell Adhes Commun 1995 0.75
119 Characterisation of the peanut lectin-binding glycoproteins of human epidermal keratinocytes. Differentiation 1990 0.75
120 Keratinocyte culture club. Nature 1982 0.75