M J Holtzman

Author PubWeight™ 63.76‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Bronchial hyperreactivity. Am Rev Respir Dis 1980 4.77
2 O3-induced change in bronchial reactivity to methacholine and airway inflammation in humans. J Appl Physiol (1985) 1986 2.16
3 Importance of airway inflammation for hyperresponsiveness induced by ozone. Am Rev Respir Dis 1983 1.85
4 Effect of ganglionic blockade on bronchial reactivity in atopic subjects. Am Rev Respir Dis 1980 1.81
5 Interleukin 12 p40 production by barrier epithelial cells during airway inflammation. J Exp Med 2001 1.68
6 Stat1 depends on transcriptional synergy with Sp1. J Biol Chem 1995 1.66
7 Direct suppression of Stat1 function during adenoviral infection. Immunity 1998 1.62
8 Constitutive activation of an epithelial signal transducer and activator of transcription (STAT) pathway in asthma. J Clin Invest 1999 1.60
9 Predominant generation of 15-lipoxygenase metabolites of arachidonic acid by epithelial cells from human trachea. Proc Natl Acad Sci U S A 1985 1.59
10 Leukotriene B4 induces airway hyperresponsiveness in dogs. J Appl Physiol (1985) 1985 1.49
11 Selective induction of intercellular adhesion molecule-1 by interferon-gamma in human airway epithelial cells. Am J Physiol 1992 1.38
12 Experimental airway inflammation and hyperreactivity. Searching for cells and mediators. Am Rev Respir Dis 1985 1.34
13 Selective interaction of a subset of interferon-gamma response element-binding proteins with the intercellular adhesion molecule-1 (ICAM-1) gene promoter controls the pattern of expression on epithelial cells. J Biol Chem 1994 1.29
14 Identification of a cyclooxygenase-related gene and its potential role in prostaglandin formation. Biochem Biophys Res Commun 1989 1.28
15 Control of neurotransmission by prostaglandins in canine trachealis smooth muscle. J Appl Physiol Respir Environ Exerc Physiol 1984 1.27
16 Selective generation of leukotriene B4 by tracheal epithelial cells from dogs. Biochem Biophys Res Commun 1983 1.26
17 Neutrophil depletion inhibits airway hyperresponsiveness induced by ozone exposure. Am Rev Respir Dis 1984 1.23
18 Patterns for RANTES secretion and intercellular adhesion molecule 1 expression mediate transepithelial T cell traffic based on analyses in vitro and in vivo. J Exp Med 1998 1.22
19 Targeted inhibition of interferon-gamma-dependent intercellular adhesion molecule-1 (ICAM-1) expression using dominant-negative Stat1. J Biol Chem 1997 1.19
20 Effect of ozone on bronchial reactivity in atopic and nonatopic subjects. Am Rev Respir Dis 1979 1.19
21 Airway hyperresponsiveness and changes in cell counts in bronchoalveolar lavage after ozone exposure in dogs. Am Rev Respir Dis 1984 1.18
22 Enhanced 5-lipoxygenase activity in lung macrophages compared to monocytes from normal subjects. J Immunol 1987 1.17
23 Virus-inducible expression of a host chemokine gene relies on replication-linked mRNA stabilization. Proc Natl Acad Sci U S A 1999 1.09
24 Enhanced prostaglandin synthesis after ultraviolet injury is mediated by endogenous histamine stimulation. A mechanism for irradiation erythema. J Clin Invest 1990 1.06
25 Resistance to Fas-mediated T cell apoptosis in asthma. J Immunol 1999 1.06
26 Epidermis contains platelet-type 12-lipoxygenase that is overexpressed in germinal layer keratinocytes in psoriasis. Am J Physiol 1994 1.02
27 Threshold concentration of ozone causing an increase in bronchial reactivity in humans and adaptation with repeated exposures. Am Rev Respir Dis 1981 1.01
28 Indomethacin inhibits the airway hyperresponsiveness but not the neutrophil influx induced by ozone in dogs. Am Rev Respir Dis 1984 1.00
29 A hierarchy for integrin expression and adhesiveness among T cell subsets that is linked to TCR gene usage and emphasizes V delta 1+ gamma delta T cell adherence and tissue retention. J Immunol 1995 1.00
30 Dose-dependent inhibition of cold air-induced bronchoconstriction by atropine. J Appl Physiol Respir Environ Exerc Physiol 1982 0.99
31 Could asthma be worsened by stimulating the T-helper type 1 immune response? Am J Respir Cell Mol Biol 2000 0.98
32 Induction of epithelial arachidonate 12-lipoxygenase at active sites of inflammatory bowel disease. Am J Physiol 1993 0.97
33 Selective differences in vascular endothelial- vs. airway epithelial-T cell adhesion mechanisms. Am J Physiol 1994 0.96
34 Interaction of serotonin with vagal- and ACh-induced bronchoconstriction in canine lungs. J Appl Physiol Respir Environ Exerc Physiol 1982 0.96
35 Histochemical evidence for induction of arachidonate 15-lipoxygenase in airway disease. Am Rev Respir Dis 1993 0.96
36 Cross-talk between interleukin 1beta (IL-1beta) and IL-6 signalling pathways: IL-1beta selectively inhibits IL-6-activated signal transducer and activator of transcription factor 1 (STAT1) by a proteasome-dependent mechanism. Biochem J 2000 0.93
37 Preferential human eosinophil chemotactic activity of the platelet-activating factor (PAF) 1-0-hexadecyl-2-acetyl-sn-glyceryl-3-phosphocholine (AGEPC). J Clin Immunol 1987 0.92
38 Interferon-gamma induces p11 gene and protein expression in human epithelial cells through interferon-gamma-activated sequences in the p11 promoter. J Biol Chem 2003 0.92
39 Identification of a novel arachidonate 12-lipoxygenase in bovine tracheal epithelial cells distinct from leukocyte and platelet forms of the enzyme. J Biol Chem 1990 0.87
40 A cryptic, microsomal-type arachidonate 12-lipoxygenase is tonically inactivated by oxidation-reduction conditions in cultured epithelial cells. J Biol Chem 1993 0.86
41 Selective expression of an arachidonate 12-lipoxygenase by pancreatic islet beta-cells. Am J Physiol 1992 0.85
42 Time course of airway hyperresponsiveness induced by ozone in dogs. J Appl Physiol Respir Environ Exerc Physiol 1983 0.85
43 Related expression of arachidonate 12- and 15-lipoxygenases in animal and human lung tissue. Am J Physiol 1991 0.85
44 Phospholipid fatty acid composition of pulmonary airway epithelial cells: potential substrates for oxygenation. Biochim Biophys Acta 1986 0.84
45 Intravenous versus inhaled atropine for inhibiting bronchoconstrictor responses in dogs. J Appl Physiol Respir Environ Exerc Physiol 1983 0.82
46 Prostaglandin F2 alpha increases responsiveness of pulmonary airways in dogs. Prostaglandins 1984 0.81
47 Effect of mechanical deformation of neutrophils on their CD18/ICAM-1-dependent adhesion. J Appl Physiol (1985) 2001 0.80
48 Barbiturates depress vagal motor pathway to ferret trachea at ganglia. J Appl Physiol Respir Environ Exerc Physiol 1982 0.79
49 Selective effect of general anesthetics on reflex bronchoconstrictor responses in dogs. J Appl Physiol Respir Environ Exerc Physiol 1982 0.78
50 Effect of route of atropine delivery on bronchospasm from cold air and methacholine. J Appl Physiol Respir Environ Exerc Physiol 1983 0.78
51 A molecular switch between lung development and cancer: is the tumor suppressor Rb turned on during bronchial epithelial cell differentiation and turned off in small cell lung cancer? Am J Respir Cell Mol Biol 1994 0.77
52 Molecular cloning, functional expression, and selective regulation of ovine prostaglandin H synthase-2. Biochem Biophys Res Commun 1996 0.76
53 An anti-inflammatory drug (BW755C) inhibits airway hyperresponsiveness induced by ozone in dogs. J Allergy Clin Immunol 1985 0.76
54 Antihistaminic versus anticholinergic effects of atropine on canine trachealis muscle. Am Rev Respir Dis 1983 0.75
55 Treatment of asthma and bronchoconstriction. Ration Drug Ther 1981 0.75
56 Perennial goals for the millennium. Am J Respir Cell Mol Biol 2000 0.75
57 Arachidonate 12-lipoxygenase and cyclooxygenase: PGE isomerase are predominant pathways for oxygenation in bovine tracheal epithelial cells. Am J Respir Cell Mol Biol 1989 0.75
58 Matching scientific with societal interests: charges for the new editor. Am J Respir Cell Mol Biol 1998 0.75
59 Biochemical and immunohistochemical evidence for selective expression of novel epithelial lipoxygenases. Adv Prostaglandin Thromboxane Leukot Res 1991 0.75