Published in J Biol Chem on December 22, 1995
Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathway. Biochem J (1998) 7.15
IL-10 inhibits macrophage activation and proliferation by distinct signaling mechanisms: evidence for Stat3-dependent and -independent pathways. EMBO J (1998) 2.99
Chromatin, TAFs, and a novel multiprotein coactivator are required for synergistic activation by Sp1 and SREBP-1a in vitro. Genes Dev (1998) 2.27
A feature-based approach to modeling protein-DNA interactions. PLoS Comput Biol (2008) 2.12
Regulation of c-myc expression by IFN-gamma through Stat1-dependent and -independent pathways. EMBO J (2000) 2.11
Viral induction of a chronic asthma phenotype and genetic segregation from the acute response. J Clin Invest (2002) 2.06
Interactions between STAT and non-STAT proteins in the interferon-stimulated gene factor 3 transcription complex. Mol Cell Biol (1996) 1.94
Transcriptional regulation of the thyrotropin-releasing hormone gene by leptin and melanocortin signaling. J Clin Invest (2001) 1.72
Interleukin 12 p40 production by barrier epithelial cells during airway inflammation. J Exp Med (2001) 1.68
Constitutive activation of an epithelial signal transducer and activator of transcription (STAT) pathway in asthma. J Clin Invest (1999) 1.60
Interleukin-6-specific activation of the C/EBPdelta gene in hepatocytes is mediated by Stat3 and Sp1. Mol Cell Biol (1998) 1.52
Linkage between STAT regulation and Epstein-Barr virus gene expression in tumors. J Virol (2001) 1.39
Patterns for RANTES secretion and intercellular adhesion molecule 1 expression mediate transepithelial T cell traffic based on analyses in vitro and in vivo. J Exp Med (1998) 1.22
Specific DNA binding of Stat5, but not of glucocorticoid receptor, is required for their functional cooperation in the regulation of gene transcription. Mol Cell Biol (1997) 1.20
Interaction between STAT-3 and HNF-3 leads to the activation of liver-specific hepatitis B virus enhancer 1 function. J Virol (2002) 1.18
Functional differences between Stat3alpha and Stat3beta. Mol Cell Biol (1997) 1.11
A novel form of human STAT1 deficiency impairing early but not late responses to interferons. Blood (2010) 1.11
STAT signaling in the pathogenesis and treatment of cancer. Mol Med (1999) 1.11
Virus-inducible expression of a host chemokine gene relies on replication-linked mRNA stabilization. Proc Natl Acad Sci U S A (1999) 1.09
Acute and chronic airway responses to viral infection: implications for asthma and chronic obstructive pulmonary disease. Proc Am Thorac Soc (2005) 1.08
Characterization of human involucrin promoter distal regulatory region transcriptional activator elements-a role for Sp1 and AP1 binding sites. Biochem J (1998) 1.07
A soluble factor(s) secreted from CD8(+) T lymphocytes inhibits human immunodeficiency virus type 1 replication through STAT1 activation. J Virol (2002) 1.03
The linker domain of Stat1 is required for gamma interferon-driven transcription. Mol Cell Biol (1999) 0.99
Negative regulation of STAT92E by an N-terminally truncated STAT protein derived from an alternative promoter site. Genes Dev (2002) 0.98
Sp1 and AP-1 regulate expression of the human gene VIL2 in esophageal carcinoma cells. J Biol Chem (2009) 0.97
RelA-associated inhibitor blocks transcription of human immunodeficiency virus type 1 by inhibiting NF-kappaB and Sp1 actions. J Virol (2002) 0.97
Interleukin-21 receptor gene induction in human T cells is mediated by T-cell receptor-induced Sp1 activity. Mol Cell Biol (2005) 0.96
Regulation of Sp1 by cell cycle related proteins. Cell Cycle (2008) 0.94
Mast cell homeostasis and the JAK-STAT pathway. Genes Immun (2010) 0.94
Hypoxia-inducible factor-1alpha enhances haptoglobin gene expression by improving binding of STAT3 to the promoter. J Biol Chem (2011) 0.92
Inhibition of IFN-gamma-dependent antiviral airway epithelial defense by cigarette smoke. Respir Res (2010) 0.92
Crosstalk of Sp1 and Stat3 signaling in pancreatic cancer pathogenesis. Cytokine Growth Factor Rev (2012) 0.92
Host epithelial-viral interactions as cause and cure for asthma. Curr Opin Immunol (2011) 0.89
Transcription factor ZBP-89 is required for STAT1 constitutive expression. Nucleic Acids Res (2003) 0.89
Advances in the understanding of cytokine signal transduction: the role of Jaks and STATs in immunoregulation and the pathogenesis of immunodeficiency. J Clin Immunol (1997) 0.88
Janus kinases and signal transducers and activators of transcription: their roles in cytokine signaling, development and immunoregulation. Arthritis Res (1999) 0.87
A novel nuclear zinc finger protein EZI enhances nuclear retention and transactivation of STAT3. EMBO J (2002) 0.87
Mammary gland expression of mouse mammary tumor virus is regulated by a novel element in the long terminal repeat. J Virol (1999) 0.85
Sp1 and AP2 regulate but do not constitute TATA-less human TAF(II)55 core promoter activity. Nucleic Acids Res (2002) 0.84
Regulation of telomerase activity by interferon regulatory factors 4 and 8 in immune cells. Mol Cell Biol (2008) 0.83
Regulation of bacteria-induced intercellular adhesion molecule-1 by CCAAT/enhancer binding proteins. Am J Respir Cell Mol Biol (2008) 0.82
Transcription of human resistin gene involves an interaction of Sp1 with peroxisome proliferator-activating receptor gamma (PPARgamma). PLoS One (2010) 0.81
FAS rs2234767 and rs1800682 polymorphisms jointly contributed to risk of colorectal cancer by affecting SP1/STAT1 complex recruitment to chromatin. Sci Rep (2016) 0.80
A motif-independent metric for DNA sequence specificity. BMC Bioinformatics (2011) 0.78
Association of FAS gene polymorphisms with systemic lupus erythematosus: A case-control study and meta-analysis. Exp Ther Med (2012) 0.77
Tannic acid inhibits EGFR/STAT1/3 and enhances p38/STAT1 signalling axis in breast cancer cells. J Cell Mol Med (2016) 0.75
Fas-670A>G polymorphism is not associated with an increased risk of acute myeloid leukemia development. Biomed Rep (2015) 0.75
Discovery and validation of information theory-based transcription factor and cofactor binding site motifs. Nucleic Acids Res (2016) 0.75
Novel STAT binding elements mediate IL-6 regulation of MMP-1 and MMP-3. Sci Rep (2017) 0.75
Bronchial hyperreactivity. Am Rev Respir Dis (1980) 4.77
O3-induced change in bronchial reactivity to methacholine and airway inflammation in humans. J Appl Physiol (1985) (1986) 2.16
Importance of airway inflammation for hyperresponsiveness induced by ozone. Am Rev Respir Dis (1983) 1.85
Effect of ganglionic blockade on bronchial reactivity in atopic subjects. Am Rev Respir Dis (1980) 1.81
The activation of human skin fibroblast procollagenase. Sequence identification of the major conversion products. J Biol Chem (1987) 1.78
Interleukin 12 p40 production by barrier epithelial cells during airway inflammation. J Exp Med (2001) 1.68
Integrin alpha 2 beta 1 (VLA-2) mediates reorganization and contraction of collagen matrices by human cells. Cell (1991) 1.65
Direct suppression of Stat1 function during adenoviral infection. Immunity (1998) 1.62
Constitutive activation of an epithelial signal transducer and activator of transcription (STAT) pathway in asthma. J Clin Invest (1999) 1.60
Predominant generation of 15-lipoxygenase metabolites of arachidonic acid by epithelial cells from human trachea. Proc Natl Acad Sci U S A (1985) 1.59
Leukotriene B4 induces airway hyperresponsiveness in dogs. J Appl Physiol (1985) (1985) 1.49
Human skin fibroblast procollagenase: mechanisms of activation by organomercurials and trypsin. Biochemistry (1983) 1.39
Selective induction of intercellular adhesion molecule-1 by interferon-gamma in human airway epithelial cells. Am J Physiol (1992) 1.38
Human skin fibroblast collagenase: interaction with substrate and inhibitor. Coll Relat Res (1985) 1.37
Experimental airway inflammation and hyperreactivity. Searching for cells and mediators. Am Rev Respir Dis (1985) 1.34
Selective interaction of a subset of interferon-gamma response element-binding proteins with the intercellular adhesion molecule-1 (ICAM-1) gene promoter controls the pattern of expression on epithelial cells. J Biol Chem (1994) 1.29
Identification of a cyclooxygenase-related gene and its potential role in prostaglandin formation. Biochem Biophys Res Commun (1989) 1.28
Control of neurotransmission by prostaglandins in canine trachealis smooth muscle. J Appl Physiol Respir Environ Exerc Physiol (1984) 1.27
Selective generation of leukotriene B4 by tracheal epithelial cells from dogs. Biochem Biophys Res Commun (1983) 1.26
Neutrophil depletion inhibits airway hyperresponsiveness induced by ozone exposure. Am Rev Respir Dis (1984) 1.23
Patterns for RANTES secretion and intercellular adhesion molecule 1 expression mediate transepithelial T cell traffic based on analyses in vitro and in vivo. J Exp Med (1998) 1.22
Targeted inhibition of interferon-gamma-dependent intercellular adhesion molecule-1 (ICAM-1) expression using dominant-negative Stat1. J Biol Chem (1997) 1.19
Effect of ozone on bronchial reactivity in atopic and nonatopic subjects. Am Rev Respir Dis (1979) 1.19
Airway hyperresponsiveness and changes in cell counts in bronchoalveolar lavage after ozone exposure in dogs. Am Rev Respir Dis (1984) 1.18
Enhanced 5-lipoxygenase activity in lung macrophages compared to monocytes from normal subjects. J Immunol (1987) 1.17
Purification and properties of rat uterine procollagenase. Arch Biochem Biophys (1983) 1.15
The gelatinolytic activity of rat uterus collagenase. J Biol Chem (1985) 1.13
Virus-inducible expression of a host chemokine gene relies on replication-linked mRNA stabilization. Proc Natl Acad Sci U S A (1999) 1.09
Enhanced prostaglandin synthesis after ultraviolet injury is mediated by endogenous histamine stimulation. A mechanism for irradiation erythema. J Clin Invest (1990) 1.06
Resistance to Fas-mediated T cell apoptosis in asthma. J Immunol (1999) 1.06
Epidermis contains platelet-type 12-lipoxygenase that is overexpressed in germinal layer keratinocytes in psoriasis. Am J Physiol (1994) 1.02
Threshold concentration of ozone causing an increase in bronchial reactivity in humans and adaptation with repeated exposures. Am Rev Respir Dis (1981) 1.01
Indomethacin inhibits the airway hyperresponsiveness but not the neutrophil influx induced by ozone in dogs. Am Rev Respir Dis (1984) 1.00
A hierarchy for integrin expression and adhesiveness among T cell subsets that is linked to TCR gene usage and emphasizes V delta 1+ gamma delta T cell adherence and tissue retention. J Immunol (1995) 1.00
Dose-dependent inhibition of cold air-induced bronchoconstriction by atropine. J Appl Physiol Respir Environ Exerc Physiol (1982) 0.99
Characteristics of the action of human skin fibroblast collagenase on fibrillar collagen. J Biol Chem (1980) 0.98
Could asthma be worsened by stimulating the T-helper type 1 immune response? Am J Respir Cell Mol Biol (2000) 0.98
Induction of epithelial arachidonate 12-lipoxygenase at active sites of inflammatory bowel disease. Am J Physiol (1993) 0.97
Histochemical evidence for induction of arachidonate 15-lipoxygenase in airway disease. Am Rev Respir Dis (1993) 0.96
Selective differences in vascular endothelial- vs. airway epithelial-T cell adhesion mechanisms. Am J Physiol (1994) 0.96
Interaction of serotonin with vagal- and ACh-induced bronchoconstriction in canine lungs. J Appl Physiol Respir Environ Exerc Physiol (1982) 0.96
Interferon-gamma induces p11 gene and protein expression in human epithelial cells through interferon-gamma-activated sequences in the p11 promoter. J Biol Chem (2003) 0.92
Preferential human eosinophil chemotactic activity of the platelet-activating factor (PAF) 1-0-hexadecyl-2-acetyl-sn-glyceryl-3-phosphocholine (AGEPC). J Clin Immunol (1987) 0.92
Identification of a novel arachidonate 12-lipoxygenase in bovine tracheal epithelial cells distinct from leukocyte and platelet forms of the enzyme. J Biol Chem (1990) 0.87
A cryptic, microsomal-type arachidonate 12-lipoxygenase is tonically inactivated by oxidation-reduction conditions in cultured epithelial cells. J Biol Chem (1993) 0.86
Selective expression of an arachidonate 12-lipoxygenase by pancreatic islet beta-cells. Am J Physiol (1992) 0.85
Time course of airway hyperresponsiveness induced by ozone in dogs. J Appl Physiol Respir Environ Exerc Physiol (1983) 0.85
Spectroscopic studies on the mixed disulfide formation of lens crystallin with glutathione. Exp Eye Res (1987) 0.85
Related expression of arachidonate 12- and 15-lipoxygenases in animal and human lung tissue. Am J Physiol (1991) 0.85
Phospholipid fatty acid composition of pulmonary airway epithelial cells: potential substrates for oxygenation. Biochim Biophys Acta (1986) 0.84
Regulation of collagenase production by steroids in uterine smooth muscle cells: an enzymatic and immunologic study. J Cell Physiol (1990) 0.83
Destabilization of lens protein conformation by glutathione mixed disulfide. Exp Eye Res (1988) 0.83
Antiepileptic efficacy of topiramate: assessment in two in vitro seizure models. Brain Res (2000) 0.83
Benzodiazepine antagonists reduce epileptiform discharges in rat hippocampal slices. Epilepsia (1996) 0.82
Intravenous versus inhaled atropine for inhibiting bronchoconstrictor responses in dogs. J Appl Physiol Respir Environ Exerc Physiol (1983) 0.82
Prostaglandin F2 alpha increases responsiveness of pulmonary airways in dogs. Prostaglandins (1984) 0.81
Effect of mechanical deformation of neutrophils on their CD18/ICAM-1-dependent adhesion. J Appl Physiol (1985) (2001) 0.80
Barbiturates depress vagal motor pathway to ferret trachea at ganglia. J Appl Physiol Respir Environ Exerc Physiol (1982) 0.79
Selective effect of general anesthetics on reflex bronchoconstrictor responses in dogs. J Appl Physiol Respir Environ Exerc Physiol (1982) 0.78
Effect of route of atropine delivery on bronchospasm from cold air and methacholine. J Appl Physiol Respir Environ Exerc Physiol (1983) 0.78
Prostaglandin H synthase and lipoxygenase gene families in the epithelial cell barrier. Ann N Y Acad Sci (1994) 0.78
A molecular switch between lung development and cancer: is the tumor suppressor Rb turned on during bronchial epithelial cell differentiation and turned off in small cell lung cancer? Am J Respir Cell Mol Biol (1994) 0.77
Serotonin: an inducer of collagenase in myometrial smooth muscle cells. J Cell Physiol (1991) 0.76
Benzodiazepine antagonist flumazenil reduces hippocampal epileptiform activity. Neuroreport (1995) 0.76
An anti-inflammatory drug (BW755C) inhibits airway hyperresponsiveness induced by ozone in dogs. J Allergy Clin Immunol (1985) 0.76
Molecular cloning, functional expression, and selective regulation of ovine prostaglandin H synthase-2. Biochem Biophys Res Commun (1996) 0.76
Comments on the paper entitled "Concentration dependency of the BAC/BrAC (blood alcohol concentration/breath alcohol concentration) conversion factor during the linear elimination phase" by H.-T. Haffner et al. Int J Legal Med (2004) 0.75
Antihistaminic versus anticholinergic effects of atropine on canine trachealis muscle. Am Rev Respir Dis (1983) 0.75
Fluorescence polarization studies of fluorescein isothiocyanate conjugates of bovine lens crystallins. Exp Eye Res (1988) 0.75
Matching scientific with societal interests: charges for the new editor. Am J Respir Cell Mol Biol (1998) 0.75
Arachidonate 12-lipoxygenase and cyclooxygenase: PGE isomerase are predominant pathways for oxygenation in bovine tracheal epithelial cells. Am J Respir Cell Mol Biol (1989) 0.75
Treatment of asthma and bronchoconstriction. Ration Drug Ther (1981) 0.75
Front surface fluorometric study of lens insoluble proteins. Curr Eye Res (1988) 0.75
Biochemical and immunohistochemical evidence for selective expression of novel epithelial lipoxygenases. Adv Prostaglandin Thromboxane Leukot Res (1991) 0.75
Perennial goals for the millennium. Am J Respir Cell Mol Biol (2000) 0.75