Published in Am Rev Respir Dis on July 01, 1980
Respiratory symptoms and bronchial reactivity: identification of a syndrome and its relation to asthma. Br Med J (Clin Res Ed) (1986) 2.24
Induction of bronchial hypersensitivity: evidence for a role for prostaglandins. Thorax (1981) 1.34
Airway responsiveness in wheezy infants: evidence for functional beta adrenergic receptors. Thorax (1987) 1.17
Effect of terbutaline sulphate in chronic "allergic" cough. Br Med J (Clin Res Ed) (1983) 1.14
Muscarinic receptor antagonists, from folklore to pharmacology; finding drugs that actually work in asthma and COPD. Br J Pharmacol (2011) 1.07
Comparison of histamine and methacholine for use in bronchial challenge tests in community studies. Thorax (1988) 1.05
Inflammation-induced plasticity of the afferent innervation of the airways. Environ Health Perspect (2001) 1.00
Time-dependent effect of prostaglandin E2 inhalation on airway responses to bronchoconstrictor agents in normal subjects. Thorax (1982) 0.99
Effect of endogenous nitric oxide inhibition on airway responsiveness to histamine and adenosine-5'-monophosphate in asthma. Thorax (1998) 0.99
Hyperventilation-induced asthma: evidence for two mechanisms. Thorax (1982) 0.92
Regulation of baseline cholinergic tone in guinea-pig airway smooth muscle. J Physiol (1999) 0.91
Dysfunction of muscarinic M2 receptors after the early allergic reaction: possible contribution to bronchial hyperresponsiveness in allergic guinea-pigs. Br J Pharmacol (1995) 0.86
Effect of inhaled frusemide on responses of airways to bradykinin and adenosine 5'-monophosphate in asthma. Thorax (1994) 0.84
Muscarinic receptor antagonists: effects on pulmonary function. Handb Exp Pharmacol (2012) 0.83
Contribution of a cholinergic reflex mechanism to allergen-induced bronchial hyperreactivity in permanently instrumented, unrestrained guinea-pigs. Br J Pharmacol (1995) 0.82
Leukotriene D4 potentiates histamine-induced bronchoconstriction in guinea-pigs. Agents Actions (1984) 0.82
Comparative effects of rilmenidine and clonidine on bronchial responses to histamine in asthmatic subjects. Br J Clin Pharmacol (1988) 0.78
Airway response to methacholine during exercise induced refractoriness in asthma. Thorax (1986) 0.77
Pathogenesis of asthma: a review. J R Soc Med (1983) 0.77
Measurement of bronchial reactivity: a question of interpretation. Thorax (1982) 0.75
The death of a volunteer research subject: lessons to be learned. CMAJ (2001) 0.75
Mechanisms of bronchial hyperreactivity in normal subjects after upper respiratory tract infection. Am Rev Respir Dis (1976) 6.26
Bronchial hyperreactivity. Am Rev Respir Dis (1980) 4.77
Comparison of regularly scheduled with as-needed use of albuterol in mild asthma. Asthma Clinical Research Network. N Engl J Med (1996) 4.03
Inhaled corticosteroid reduction and elimination in patients with persistent asthma receiving salmeterol: a randomized controlled trial. JAMA (2001) 3.21
A new perspective on concepts of asthma severity and control. Eur Respir J (2008) 3.16
Role of autonomic nervous system and the cough reflex in the increased responsiveness of airways in patients with obstructive airway disease. J Clin Invest (1967) 3.09
The effect of polymorphisms of the beta(2)-adrenergic receptor on the response to regular use of albuterol in asthma. Am J Respir Crit Care Med (2000) 3.08
New method for perfusing bronchial arteries: histamine bronchoconstriction and apnea. J Appl Physiol (1966) 2.98
Prominent neutrophilic inflammation in sputum from subjects with asthma exacerbation. J Allergy Clin Immunol (1995) 2.88
Epidermal growth factor system regulates mucin production in airways. Proc Natl Acad Sci U S A (1999) 2.57
The response of laryngeal afferent fibres to mechanical and chemical stimuli. J Physiol (1974) 2.50
Role of leukotrienes revealed by targeted disruption of the 5-lipoxygenase gene. Nature (1994) 2.37
Cellular and biochemical analysis of induced sputum from asthmatic and from healthy subjects. Am Rev Respir Dis (1993) 2.34
Lower threshold and greater bronchomotor responsiveness of asthmatic subjects to sulfur dioxide. Am Rev Respir Dis (1980) 2.31
The effect of an anti-IgE monoclonal antibody on the early- and late-phase responses to allergen inhalation in asthmatic subjects. Am J Respir Crit Care Med (1997) 2.28
Transcriptional activation of mucin by Pseudomonas aeruginosa lipopolysaccharide in the pathogenesis of cystic fibrosis lung disease. Proc Natl Acad Sci U S A (1997) 2.24
O3-induced change in bronchial reactivity to methacholine and airway inflammation in humans. J Appl Physiol (1985) (1986) 2.16
Characterization of human tracheal epithelial cells transformed by an origin-defective simian virus 40. Proc Natl Acad Sci U S A (1988) 2.15
Interleukin-8: an important chemoattractant in sputum of patients with chronic inflammatory airway diseases. Am J Physiol (1993) 2.14
Alteration in osmolarity of inhaled aerosols cause bronchoconstriction and cough, but absence of a permeant anion causes cough alone. Am Rev Respir Dis (1984) 2.05
Effect of histamine, serotonin, and acetylcholine on the peripheral airways. J Appl Physiol (1966) 1.95
Attrition and retention of ethnically diverse subjects in a multicenter randomized controlled research trial. Control Clin Trials (2001) 1.90
Oxidative stress causes mucin synthesis via transactivation of epidermal growth factor receptor: role of neutrophils. J Immunol (2000) 1.88
IL-4 induces mucin gene expression and goblet cell metaplasia in vitro and in vivo. J Immunol (1999) 1.88
Exercise increases sulfur dioxide-induced bronchoconstriction in asthmatic subjects. Am Rev Respir Dis (1981) 1.86
Novel Pseudomonas product stimulates interleukin-8 production in airway epithelial cells in vitro. J Clin Invest (1994) 1.85
Importance of airway inflammation for hyperresponsiveness induced by ozone. Am Rev Respir Dis (1983) 1.85
Rhinovirus-16 colds in healthy and in asthmatic subjects: similar changes in upper and lower airways. Am J Respir Crit Care Med (1999) 1.85
Ethnic differences: word descriptors used by African-American and white asthma patients during induced bronchoconstriction. Chest (2000) 1.84
Bronchial hyperirritability in healthy subjects after exposure to ozone. Am Rev Respir Dis (1978) 1.82
Use of pulse oximetry to recognize severity of airflow obstruction in obstructive airway disease: correlation with pulsus paradoxus. Chest (1999) 1.77
Molecular cloning and primary structure of human 15-lipoxygenase. Biochem Biophys Res Commun (1988) 1.76
Effects of allergic inflammation of the nasal mucosa on the severity of rhinovirus 16 cold. J Allergy Clin Immunol (2000) 1.74
Sympathetic versus parasympathetic nervous regulation of airways in dogs. J Appl Physiol (1971) 1.71
Active transport of Na+ and Cl- across the canine tracheal epithelium in vitro. Am Rev Respir Dis (1975) 1.71
Predicting worsening asthma control following the common cold. Eur Respir J (2008) 1.70
Relationship between airway inflammation, hyperresponsiveness, and obstruction in asthma. J Allergy Clin Immunol (2001) 1.68
Interleukin 12 p40 production by barrier epithelial cells during airway inflammation. J Exp Med (2001) 1.68
Mechanism of cough and bronchoconstriction induced by distilled water aerosol. Am Rev Respir Dis (1983) 1.66
Stat1 depends on transcriptional synergy with Sp1. J Biol Chem (1995) 1.66
Airway inflammation and remodeling in asthma. Curr Opin Pulm Med (2000) 1.64
Bronchial hyperresponsiveness in normal subjects during attenuated influenza virus infection. Am Rev Respir Dis (1991) 1.64
Airway hyperresponsiveness induced by platelet-activating factor: role of thromboxane generation. J Pharmacol Exp Ther (1986) 1.62
Assessment of oxidant stress in allergic asthma by measurement of the major urinary metabolite of F2-isoprostane, 15-F2t-IsoP (8-iso-PGF2alpha). Clin Exp Allergy (2001) 1.62
Direct suppression of Stat1 function during adenoviral infection. Immunity (1998) 1.62
Resistance of differentiated human airway epithelium to infection by rhinovirus. Am J Physiol Lung Cell Mol Physiol (2004) 1.61
Constitutive activation of an epithelial signal transducer and activator of transcription (STAT) pathway in asthma. J Clin Invest (1999) 1.60
Activation of epidermal growth factor receptors is responsible for mucin synthesis induced by cigarette smoke. Am J Physiol Lung Cell Mol Physiol (2001) 1.59
Predominant generation of 15-lipoxygenase metabolites of arachidonic acid by epithelial cells from human trachea. Proc Natl Acad Sci U S A (1985) 1.59
Safety and reproducibility of sputum induction in asthmatic subjects in a multicenter study. Am J Respir Crit Care Med (2001) 1.58
Roles of epidermal growth factor receptor activation in epithelial cell repair and mucin production in airway epithelium. Thorax (2004) 1.57
Postpneumonic empyema in childhood: selecting appropriate therapy. J Pediatr Surg (1989) 1.56
Resistance to breathing during exercise-induced asthma attacks. Am Rev Respir Dis (1970) 1.55
Effect of oral prednisone on airway inflammatory mediators in atopic asthma. Am J Respir Crit Care Med (1994) 1.54
Relationship of epidermal growth factor receptors to goblet cell production in human bronchi. Am J Respir Crit Care Med (2001) 1.54
Analysis of induced sputum to examine the effects of prednisone on airway inflammation in asthmatic subjects. J Allergy Clin Immunol (1994) 1.54
Mechanisms by which histamine stimulates rapidly adapting receptors in dog lungs. J Appl Physiol Respir Environ Exerc Physiol (1977) 1.53
IL-13 induces mucin production by stimulating epidermal growth factor receptors and by activating neutrophils. Am J Physiol Lung Cell Mol Physiol (2001) 1.52
Comparison of samples collected by sputum induction and bronchoscopy from asthmatic and healthy subjects. Am J Respir Crit Care Med (1995) 1.52
Leukotriene B4 induces airway hyperresponsiveness in dogs. J Appl Physiol (1985) (1985) 1.49
Enkephalinase inhibitor potentiates mammalian tachykinin-induced contraction in ferret trachea. J Pharmacol Exp Ther (1987) 1.48
Epidermal growth factor receptor-mediated innate immune responses and their roles in airway diseases. Eur Respir J (2008) 1.44
Autonomic regulation of the airways. Annu Rev Med (1984) 1.42
Neutrophil elastase and cathepsin G stimulate secretion from cultured bovine airway gland serous cells. J Clin Invest (1990) 1.42
Preferential role for NF-kappa B/Rel signaling in the type 1 but not type 2 T cell-dependent immune response in vivo. J Immunol (1999) 1.41
Substance P and vasoactive intestinal peptide degradation by mast cell tryptase and chymase. J Pharmacol Exp Ther (1988) 1.40
Inhibition of eicosanoid biosynthesis by glucocorticoids in humans. Proc Natl Acad Sci U S A (1990) 1.38
Selective induction of intercellular adhesion molecule-1 by interferon-gamma in human airway epithelial cells. Am J Physiol (1992) 1.38
Experimental airway inflammation and hyperreactivity. Searching for cells and mediators. Am Rev Respir Dis (1985) 1.34
Respiratory syncytial virus infection prolongs methacholine-induced airway hyperresponsiveness in ovalbumin-sensitized mice. J Med Virol (1999) 1.34
Influenza infection causes airway hyperresponsiveness by decreasing enkephalinase. J Appl Physiol (1985) (1988) 1.33
Physiologic diagnosis of subclinical emphysema. Am Rev Respir Dis (1973) 1.32
Elastic recoil of the lungs in chronic asthmatic patients before and after therapy. J Appl Physiol (1967) 1.32
Enkephalinase inhibitor potentiates substance P- and electrically induced contraction in ferret trachea. J Appl Physiol (1985) (1987) 1.31
Autonomic control of airway smooth muscle and airway secretions. Am Rev Respir Dis (1977) 1.31
Enkephalinase inhibitors potentiate substance P-induced secretion of 35SO4-macromolecules from ferret trachea. Exp Lung Res (1987) 1.31
Virus induces airway hyperresponsiveness to tachykinins: role of neutral endopeptidase. J Appl Physiol (1985) (1989) 1.30
Localization of beta-adrenoreceptors in mammalian lung by light microscopic autoradiography. Nature (1982) 1.30
Selective interaction of a subset of interferon-gamma response element-binding proteins with the intercellular adhesion molecule-1 (ICAM-1) gene promoter controls the pattern of expression on epithelial cells. J Biol Chem (1994) 1.29
Cigarette smoke induces bronchoconstrictor hyperresponsiveness to substance P and inactivates airway neutral endopeptidase in the guinea pig. Possible role of free radicals. J Clin Invest (1989) 1.29
Reflex effects of laryngeal irritation on the pattern of breathing and total lung resistance. J Physiol (1972) 1.28
Inhibition of respiratory reflexes by local anesthetic aerosols in dogs and rabbits. J Appl Physiol (1975) 1.28
Identification of a cyclooxygenase-related gene and its potential role in prostaglandin formation. Biochem Biophys Res Commun (1989) 1.28
The reflex effects of intralaryngeal carbon dioxide on the pattern of breathing. J Physiol (1973) 1.28
Effect of the oronasal breathing route on sulfur dioxide-induced bronchoconstriction in exercising asthmatic subjects. Am Rev Respir Dis (1982) 1.27
Control of neurotransmission by prostaglandins in canine trachealis smooth muscle. J Appl Physiol Respir Environ Exerc Physiol (1984) 1.27