Published in J Immunol on February 01, 2001
In vivo depletion of CD11c+ dendritic cells abrogates priming of CD8+ T cells by exogenous cell-associated antigens. Immunity (2002) 14.57
Immune tolerance after delivery of dying cells to dendritic cells in situ. J Exp Med (2002) 3.35
The CD8alpha(+) dendritic cell is responsible for inducing peripheral self-tolerance to tissue-associated antigens. J Exp Med (2002) 2.93
Constitutive presentation of a natural tissue autoantigen exclusively by dendritic cells in the draining lymph node. J Exp Med (2002) 2.78
Cross-priming in health and disease. Nat Rev Immunol (2010) 2.51
Phenotypic and functional analysis of CD8(+) T cells undergoing peripheral deletion in response to cross-presentation of self-antigen. J Exp Med (2001) 2.49
Skin-derived dendritic cells induce potent CD8(+) T cell immunity in recombinant lentivector-mediated genetic immunization. Immunity (2006) 1.95
Peripheral deletion of autoreactive CD8 T cells by cross presentation of self-antigen occurs by a Bcl-2-inhibitable pathway mediated by Bim. J Exp Med (2002) 1.89
Organ-dependent in vivo priming of naive CD4+, but not CD8+, T cells by plasmacytoid dendritic cells. J Exp Med (2007) 1.68
Mouse models for the study of autoimmune type 1 diabetes: a NOD to similarities and differences to human disease. Semin Immunopathol (2010) 1.58
Antibody-enhanced cross-presentation of self antigen breaks T cell tolerance. J Clin Invest (2007) 1.51
Uncoupling of proliferative potential and gain of effector function by CD8(+) T cells responding to self-antigens. J Exp Med (2002) 1.44
Fc gamma receptors and cross-presentation in dendritic cells. J Exp Med (2002) 1.43
Non-hematopoietic cells in lymph nodes drive memory CD8 T cell inflation during murine cytomegalovirus infection. PLoS Pathog (2011) 1.17
The early expression of glycoprotein B from herpes simplex virus can be detected by antigen-specific CD8+ T cells. J Virol (2003) 1.16
Beta cell MHC class I is a late requirement for diabetes. Proc Natl Acad Sci U S A (2003) 1.12
Pathways for antigen cross presentation. Springer Semin Immunopathol (2004) 1.10
Role of T cells and dendritic cells in glomerular immunopathology. Semin Immunopathol (2007) 1.08
Beta cells cannot directly prime diabetogenic CD8 T cells in nonobese diabetic mice. Proc Natl Acad Sci U S A (2007) 1.07
Cross-presentation: dendritic cells and macrophages bite off more than they can chew! Immunology (2004) 1.01
Lipids, apoptosis, and cross-presentation: links in the chain of host defense against Mycobacterium tuberculosis. Microbes Infect (2011) 0.98
CD169+ macrophages are sufficient for priming of CTLs with specificities left out by cross-priming dendritic cells. Proc Natl Acad Sci U S A (2015) 0.94
Dendritic cells program non-immunogenic prostate-specific T cell responses beginning at early stages of prostate tumorigenesis. Prostate (2007) 0.94
Generation of tumor-associated cytotoxic T lymphocytes requires interleukin 4 from CD8(+) T cells. J Exp Med (2001) 0.93
EGFRvIII-targeted immunotoxin induces antitumor immunity that is inhibited in the absence of CD4+ and CD8+ T cells. Cancer Immunol Immunother (2007) 0.92
Comparative therapeutic effects of orally administered 1,25-dihydroxyvitamin D(3) and 1alpha-hydroxyvitamin D(3) on type-1 diabetes in non-obese diabetic mice fed a normal-calcaemic diet. Clin Exp Immunol (2007) 0.91
Immune tolerance and transplantation. Semin Oncol (2012) 0.90
Rabbit polyclonal mouse antithymocyte globulin administration alters dendritic cell profile and function in NOD mice to suppress diabetogenic responses. J Immunol (2009) 0.89
CD8+ regulatory T cells generated by neonatal recognition of peripheral self-antigen. Proc Natl Acad Sci U S A (2006) 0.88
Steady state dendritic cells present parenchymal self-antigen and contribute to, but are not essential for, tolerization of naive and Th1 effector CD4 cells. J Immunol (2007) 0.85
Tissue destruction caused by cytotoxic T lymphocytes induces deletional tolerance. Proc Natl Acad Sci U S A (2009) 0.85
The immunotherapeutic potential of dendritic cells in type 1 diabetes. Clin Exp Immunol (2010) 0.84
Dendritic cell mediated delivery of plasmid DNA encoding LAMP/HIV-1 Gag fusion immunogen enhances T cell epitope responses in HLA DR4 transgenic mice. PLoS One (2010) 0.84
Betting on improved cancer immunotherapy by doubling down on CD134 and CD137 co-stimulation. Oncoimmunology (2013) 0.82
Antigen presentation by dendritic cells in vivo. J Exp Med (2002) 0.80
Peripheral Tolerization of Effector and Memory T Cells: Implications for Autoimmunity and Tumor-Immunity. Curr Immunol Rev (2005) 0.79
Abortive activation precedes functional deletion of CD8+ T cells following encounter with self-antigens expressed by resting B cells in vivo. Immunology (2006) 0.78
Immunological tolerance to muscle autoantigens involves peripheral deletion of autoreactive CD8+ T cells. PLoS One (2012) 0.78
Dendritic cells enhance the antigen sensitivity of T cells. Front Immunol (2012) 0.77
Induction/engineering, detection, selection, and expansion of clinical-grade human antigen-specific CD8 cytotoxic T cell clones for adoptive immunotherapy. J Biomed Biotechnol (2010) 0.76
Enhancing the safety of antibody-based immunomodulatory cancer therapy without compromising therapeutic benefit: Can we have our cake and eat it too? Expert Opin Biol Ther (2016) 0.75
Targeted antigen delivery to DEC-205⁺ dendritic cells for tolerogenic vaccination. Rev Diabet Stud (2012) 0.75
The T cell receptor/CD3 complex is composed of at least two autonomous transduction modules. Cell (1992) 3.11
Soluble CD40 ligand can replace the normal T cell-derived CD40 ligand signal to B cells in T cell-dependent activation. J Exp Med (1993) 2.44
Compromised OX40 function in CD28-deficient mice is linked with failure to develop CXC chemokine receptor 5-positive CD4 cells and germinal centers. J Exp Med (1999) 2.15
Mutations affecting either generation or survival of cells influence the pool size of mature B cells. Immunity (1999) 1.61
Cellular interactions involved in Th cell memory. J Immunol (2000) 1.38
Co-stimulation and selection for T-cell help for germinal centres: the role of CD28 and OX40. Immunol Today (2000) 1.15
Developmental dissociation of thymic dendritic cell and thymocyte lineages revealed in growth factor receptor mutant mice. Proc Natl Acad Sci U S A (1999) 1.08
Functional comparison of thymic B cells and dendritic cells in vivo. Blood (2000) 1.03
The role of fibroblast Tiam1 in tumor cell invasion and metastasis. Oncogene (2010) 0.98
Developmental regulation of dendritic cell function. Curr Opin Immunol (1999) 0.94
CD45 up-regulation during lymphocyte maturation. Int Immunol (1996) 0.88
Expression of PIK3CA mutant E545K in the mammary gland induces heterogeneous tumors but is less potent than mutant H1047R. Oncogenesis (2013) 0.87
B-cell-specific transgene expression using a self-inactivating retroviral vector with human CD19 promoter and viral post-transcriptional regulatory element. Gene Ther (2004) 0.86
Targeted expression of MHC class II genes to dendritic cells in vivo. Immunol Lett (1997) 0.84
Role of dendritic cells in the immune response induced by mouse mammary tumor virus superantigen. J Virol (1999) 0.83
DY determinants, possibly associated with novel class II molecules, stimulate autoreactive CD4+ T cells with suppressive activity. J Exp Med (1988) 0.80
Class II essential for CD4 survival. Nat Immunol (2001) 0.80
"Tolerization" of human T-helper cell clones by chronic exposure to alloantigen: culture conditions dictate autocrine proliferative status but not acquisition of cytotoxic potential and suppressor-induction capacity. J Mol Cell Immunol (1988) 0.80
CD45 and RPTPalpha display different protein tyrosine phosphatase activities in T lymphocytes. Biochem J (1997) 0.79
Kidney protection against autoreactive CD8(+) T cells distinct from immunoprivilege and sequestration. Kidney Int (2001) 0.76
The role of CD30 in skin and heart allograft rejection in the mouse. Transplant Proc (2001) 0.75