Published in Front Immunol on December 26, 2012
The Role of Indoleamine 2, 3-Dioxygenase in Immune Suppression and Autoimmunity. Vaccines (Basel) (2015) 0.83
Independent control of natural killer cell responsiveness and homeostasis at steady-state by CD11c+ dendritic cells. Sci Rep (2016) 0.75
Central memory and effector memory T cell subsets: function, generation, and maintenance. Annu Rev Immunol (2004) 17.54
The immunological synapse: a molecular machine controlling T cell activation. Science (1999) 17.41
In vivo depletion of CD11c+ dendritic cells abrogates priming of CD8+ T cells by exogenous cell-associated antigens. Immunity (2002) 14.57
T-cell priming by dendritic cells in lymph nodes occurs in three distinct phases. Nature (2004) 11.14
Two-photon imaging of lymphocyte motility and antigen response in intact lymph node. Science (2002) 8.94
Identification of a novel cell type in peripheral lymphoid organs of mice. II. Functional properties in vitro. J Exp Med (1974) 7.58
Homing and cellular traffic in lymph nodes. Nat Rev Immunol (2003) 7.23
Stromal cell networks regulate lymphocyte entry, migration, and territoriality in lymph nodes. Immunity (2006) 7.22
Visualizing dendritic cell networks in vivo. Nat Immunol (2004) 7.13
Class I-restricted cross-presentation of exogenous self-antigens leads to deletion of autoreactive CD8(+) T cells. J Exp Med (1997) 5.72
Origin of dendritic cells in peripheral lymphoid organs of mice. Nat Immunol (2007) 5.31
Chemokines enhance immunity by guiding naive CD8+ T cells to sites of CD4+ T cell-dendritic cell interaction. Nature (2006) 5.19
Dynamics of CD8+ T cell priming by dendritic cells in intact lymph nodes. Nat Immunol (2003) 5.10
Imaging the single cell dynamics of CD4+ T cell activation by dendritic cells in lymph nodes. J Exp Med (2004) 5.08
Shaping and reshaping CD8+ T-cell memory. Nat Rev Immunol (2008) 4.88
Skin infection generates non-migratory memory CD8+ T(RM) cells providing global skin immunity. Nature (2012) 4.64
T cell sensing of antigen dose governs interactive behavior with dendritic cells and sets a threshold for T cell activation. Nat Immunol (2008) 4.52
Inflammatory mediators are insufficient for full dendritic cell activation and promote expansion of CD4+ T cell populations lacking helper function. Nat Immunol (2005) 4.22
T cell repertoire scanning is promoted by dynamic dendritic cell behavior and random T cell motility in the lymph node. Proc Natl Acad Sci U S A (2004) 3.99
Dendritic cell-induced memory T cell activation in nonlymphoid tissues. Science (2008) 3.97
T cell killing does not require the formation of a stable mature immunological synapse. Nat Immunol (2004) 3.85
Altered peptide ligand-induced partial T cell activation: molecular mechanisms and role in T cell biology. Annu Rev Immunol (1996) 3.59
Agonist/endogenous peptide-MHC heterodimers drive T cell activation and sensitivity. Nature (2005) 3.55
Intracellular signalling controlling integrin activation in lymphocytes. Nat Rev Immunol (2005) 3.54
Constitutive ablation of dendritic cells breaks self-tolerance of CD4 T cells and results in spontaneous fatal autoimmunity. J Exp Med (2009) 3.38
Dendritic cell apoptosis in the maintenance of immune tolerance. Science (2006) 3.33
Distinct T cell dynamics in lymph nodes during the induction of tolerance and immunity. Nat Immunol (2004) 3.25
Dendritic cells maximize the memory CD8 T cell response to infection. Immunity (2005) 3.21
Developmental kinetics and lifespan of dendritic cells in mouse lymphoid organs. Blood (2002) 3.19
Feedback control of regulatory T cell homeostasis by dendritic cells in vivo. J Exp Med (2009) 3.13
Antigen presentation in the thymus for positive selection and central tolerance induction. Nat Rev Immunol (2009) 3.13
Functional anatomy of T cell activation and synapse formation. Annu Rev Immunol (2010) 3.01
Tickling the TCR: selective T-cell functions stimulated by altered peptide ligands. Immunol Today (1993) 2.91
Inflammatory signals in dendritic cell activation and the induction of adaptive immunity. Immunol Rev (2009) 2.89
Stable T cell-dendritic cell interactions precede the development of both tolerance and immunity in vivo. Nat Immunol (2005) 2.89
Functional antigen-independent synapses formed between T cells and dendritic cells. Nat Immunol (2001) 2.82
CCR7 ligands stimulate the intranodal motility of T lymphocytes in vivo. J Exp Med (2007) 2.81
Dendritic cell subsets in primary and secondary T cell responses at body surfaces. Nat Immunol (2009) 2.76
Self-recognition promotes the foreign antigen sensitivity of naive T lymphocytes. Nature (2002) 2.71
Cross-priming in health and disease. Nat Rev Immunol (2010) 2.51
An endogenous positively selecting peptide enhances mature T cell responses and becomes an autoantigen in the absence of microRNA miR-181a. Nat Immunol (2009) 2.38
Minimal activation of memory CD8+ T cell by tissue-derived dendritic cells favors the stimulation of naive CD8+ T cells. Nat Immunol (2007) 2.22
T cell receptor-dependent regulation of lipid rafts controls naive CD8+ T cell homeostasis. Immunity (2010) 2.17
Preculture of PBMCs at high cell density increases sensitivity of T-cell responses, revealing cytokine release by CD28 superagonist TGN1412. Blood (2011) 2.12
Lack of conventional dendritic cells is compatible with normal development and T cell homeostasis, but causes myeloid proliferative syndrome. Immunity (2008) 2.04
What is the importance of the immunological synapse? Trends Immunol (2004) 2.02
CD4 T cells integrate signals delivered during successive DC encounters in vivo. J Exp Med (2005) 1.99
Dendritic cells are sufficient to cross-present self-antigens to CD8 T cells in vivo. J Immunol (2001) 1.96
Peptide-MHC potency governs dynamic interactions between T cells and dendritic cells in lymph nodes. Nat Immunol (2007) 1.90
The storm has cleared: lessons from the CD28 superagonist TGN1412 trial. Nat Rev Immunol (2012) 1.89
Nonstimulatory peptides contribute to antigen-induced CD8-T cell receptor interaction at the immunological synapse. Nat Immunol (2005) 1.85
Alternative cross-priming through CCL17-CCR4-mediated attraction of CTLs toward NKT cell-licensed DCs. Nat Immunol (2010) 1.81
Specific T cell recognition of minimally homologous peptides: evidence for multiple endogenous ligands. Immunity (1995) 1.80
An endogenous peptide positively selects and augments the activation and survival of peripheral CD4+ T cells. Nat Immunol (2009) 1.78
Inducible transgenic mice reveal resting dendritic cells as potent inducers of CD8+ T cell tolerance. Immunity (2003) 1.72
A novel CD11c.DTR transgenic mouse for depletion of dendritic cells reveals their requirement for homeostatic proliferation of natural killer cells. Eur J Immunol (2008) 1.68
Quantum dot/peptide-MHC biosensors reveal strong CD8-dependent cooperation between self and viral antigens that augment the T cell response. Proc Natl Acad Sci U S A (2006) 1.58
Dendritic cell-restricted CD80/86 deficiency results in peripheral regulatory T-cell reduction but is not associated with lymphocyte hyperactivation. Eur J Immunol (2011) 1.56
Antigen presentation by dendritic cells in vivo. Curr Opin Immunol (2009) 1.49
Making friends in out-of-the-way places: how cells of the immune system get together and how they conduct their business as revealed by intravital imaging. Immunol Rev (2008) 1.47
Functionally relevant neutrophilia in CD11c diphtheria toxin receptor transgenic mice. Nat Methods (2012) 1.40
Dendritic cells control T cell tonic signaling required for responsiveness to foreign antigen. Proc Natl Acad Sci U S A (2010) 1.27
CD8+ cytotoxic T lymphocyte activation by soluble major histocompatibility complex-peptide dimers. J Biol Chem (2005) 1.18
Defining the quantitative limits of intravital two-photon lymphocyte tracking. Proc Natl Acad Sci U S A (2011) 1.17
MHC class II deprivation impairs CD4 T cell motility and responsiveness to antigen-bearing dendritic cells in vivo. Proc Natl Acad Sci U S A (2007) 1.11
Quantification of lymph node transit times reveals differences in antigen surveillance strategies of naive CD4+ and CD8+ T cells. Proc Natl Acad Sci U S A (2012) 1.10
From the thymus to longevity in the periphery. Curr Opin Immunol (2010) 1.10
On the role of self-recognition in T cell responses to foreign antigen. Immunol Rev (2003) 1.09
A role for "self" in T-cell activation. Semin Immunol (2007) 1.07
The spleen in lymphocyte migration. Immunol Today (1988) 1.06
T cell activation enhancement by endogenous pMHC acts for both weak and strong agonists but varies with differentiation state. J Exp Med (2007) 1.06
Close encounters of the first and second kind: T-DC and T-B interactions in the lymph node. Semin Immunol (2005) 0.97
T cell adhesion lowers the threshold for antigen detection. Eur J Immunol (2003) 0.96
Nck adaptors are positive regulators of the size and sensitivity of the T-cell repertoire. Proc Natl Acad Sci U S A (2010) 0.95
The in situ dynamics of dendritic cell interactions. Eur J Immunol (2010) 0.90
Mechanical interactions between dendritic cells and T cells correlate with T cell responsiveness. J Immunol (2011) 0.89
Tonic T cell signalling and T cell tolerance as opposite effects of self-recognition on dendritic cells. Curr Opin Immunol (2010) 0.86
The sense of place in the immune system. Nat Immunol (2006) 0.84
Do T cells need endogenous peptides for activation? Nat Rev Immunol (2008) 0.84