Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGF beta receptor for degradation.

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Published in Mol Cell on December 01, 2000

Authors

P Kavsak1, R K Rasmussen, C G Causing, S Bonni, H Zhu, G H Thomsen, J L Wrana

Author Affiliations

1: Program in Molecular Biology and Cancer, Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto M5G 1X5, Canada.

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