Published in Nature on July 02, 1992
Cancer. p53, guardian of the genome. Nature (1992) 16.36
Cell cycle, CDKs and cancer: a changing paradigm. Nat Rev Cancer (2009) 11.25
mdm2 expression is induced by wild type p53 activity. EMBO J (1993) 8.01
The first 30 years of p53: growing ever more complex. Nat Rev Cancer (2009) 8.00
Mapping of the p53 and mdm-2 interaction domains. Mol Cell Biol (1993) 5.31
Analysis of p53-regulated gene expression patterns using oligonucleotide arrays. Genes Dev (2000) 5.04
Gene-specific requirement for P-TEFb activity and RNA polymerase II phosphorylation within the p53 transcriptional program. Genes Dev (2006) 4.06
Wild-type p53 binds to the TATA-binding protein and represses transcription. Proc Natl Acad Sci U S A (1992) 4.06
Cloning and expression of the cDNA for E6-AP, a protein that mediates the interaction of the human papillomavirus E6 oncoprotein with p53. Mol Cell Biol (1993) 4.04
Characterization of the p53-dependent postmitotic checkpoint following spindle disruption. Mol Cell Biol (1998) 3.88
The transcriptional transactivation function of wild-type p53 is inhibited by SV40 large T-antigen and by HPV-16 E6 oncoprotein. EMBO J (1992) 2.97
Localization of the E6-AP regions that direct human papillomavirus E6 binding, association with p53, and ubiquitination of associated proteins. Mol Cell Biol (1993) 2.91
DNA copy number losses in human neoplasms. Am J Pathol (1999) 2.73
Wild-type human p53 and a temperature-sensitive mutant induce Fas/APO-1 expression. Mol Cell Biol (1995) 2.62
Histone acetyltransferase activity and interaction with ADA2 are critical for GCN5 function in vivo. EMBO J (1997) 2.58
p73 function is inhibited by tumor-derived p53 mutants in mammalian cells. Mol Cell Biol (1999) 2.41
Repression of p53-mediated transcription by MDM2: a dual mechanism. Genes Dev (1997) 2.37
The p53 activation domain binds the TATA box-binding polypeptide in Holo-TFIID, and a neighboring p53 domain inhibits transcription. Mol Cell Biol (1993) 2.37
p53 Research: the past thirty years and the next thirty years. Cold Spring Harb Perspect Biol (2010) 2.34
Increased activity of p53 in senescing fibroblasts. Proc Natl Acad Sci U S A (1995) 2.27
p53-mediated cell death: relationship to cell cycle control. Mol Cell Biol (1993) 2.27
Conformational shifts propagate from the oligomerization domain of p53 to its tetrameric DNA binding domain and restore DNA binding to select p53 mutants. EMBO J (1993) 2.21
p53-catalyzed annealing of complementary single-stranded nucleic acids. EMBO J (1993) 2.16
p53 regulates a G2 checkpoint through cyclin B1. Proc Natl Acad Sci U S A (1999) 2.16
The 1993 Walter Hubert Lecture: the role of the p53 tumour-suppressor gene in tumorigenesis. Br J Cancer (1994) 2.14
Functional and physical interaction between p53 and BZLF1: implications for Epstein-Barr virus latency. Mol Cell Biol (1994) 2.12
The p53 protein is an unusually shaped tetramer that binds directly to DNA. Proc Natl Acad Sci U S A (1993) 2.11
Wild-type and mutant p53 differentially regulate transcription of the insulin-like growth factor I receptor gene. Proc Natl Acad Sci U S A (1996) 2.09
Epstein-Barr virus latent membrane protein 1 blocks p53-mediated apoptosis through the induction of the A20 gene. J Virol (1996) 2.03
DNA damage-inducible gene p33ING2 negatively regulates cell proliferation through acetylation of p53. Proc Natl Acad Sci U S A (2001) 2.00
The ability of human papillomavirus E6 proteins to target p53 for degradation in vivo correlates with their ability to abrogate actinomycin D-induced growth arrest. J Virol (1994) 1.97
p53 mutations increase resistance to ionizing radiation. Proc Natl Acad Sci U S A (1993) 1.93
Role of cysteine residues in regulation of p53 function. Mol Cell Biol (1995) 1.91
Role of Stat3 in regulating p53 expression and function. Mol Cell Biol (2005) 1.91
Transgenic mouse models that explore the multistep hypothesis of intestinal neoplasia. J Cell Biol (1993) 1.91
Expression of the papillomavirus E2 protein in HeLa cells leads to apoptosis. EMBO J (1997) 1.85
Cell type-specific inhibition of p53-mediated apoptosis by mdm2. EMBO J (1996) 1.82
Pancreatic adenocarcinomas frequently show p53 gene mutations. Am J Pathol (1993) 1.80
Wild-type p53 adopts a 'mutant'-like conformation when bound to DNA. EMBO J (1993) 1.78
Sequence-specific DNA binding by p53: identification of target sites and lack of binding to p53 - MDM2 complexes. EMBO J (1993) 1.77
Modulation of p53-mediated transcriptional repression and apoptosis by the adenovirus E1B 19K protein. Mol Cell Biol (1995) 1.76
Two domains of p53 interact with the TATA-binding protein, and the adenovirus 13S E1A protein disrupts the association, relieving p53-mediated transcriptional repression. Mol Cell Biol (1995) 1.73
p53 is a general repressor of RNA polymerase III transcription. EMBO J (1998) 1.72
p53 domains: structure, oligomerization, and transformation. Mol Cell Biol (1994) 1.68
p53 is covalently linked to 5.8S rRNA. Mol Cell Biol (1992) 1.65
Down-regulation of wild-type p53 activity interferes with apoptosis of IL-3-dependent hematopoietic cells following IL-3 withdrawal. EMBO J (1994) 1.64
Direct interaction of the hepatitis B virus HBx protein with p53 leads to inhibition by HBx of p53 response element-directed transactivation. J Virol (1995) 1.63
The dihedral symmetry of the p53 tetramerization domain mandates a conformational switch upon DNA binding. EMBO J (1995) 1.58
p53 oligomerization and DNA looping are linked with transcriptional activation. EMBO J (1994) 1.57
The adenovirus E4orf6 protein can promote E1A/E1B-induced focus formation by interfering with p53 tumor suppressor function. Proc Natl Acad Sci U S A (1997) 1.55
Inhibition of p53 DNA binding by human papillomavirus E6 proteins. J Virol (1994) 1.54
Viral oncoproteins discriminate between p53 and the p53 homolog p73. Mol Cell Biol (1998) 1.51
A temperature-sensitive mutant of human p53. EMBO J (1994) 1.51
Apoptosis induced by inhibition of intercellular contact. J Cell Biol (1994) 1.49
Activation of the cryptic DNA binding function of mutant forms of p53. Nucleic Acids Res (1993) 1.49
p53-mediated repression of alpha-fetoprotein gene expression by specific DNA binding. Mol Cell Biol (1999) 1.44
Interaction of p53 with the human Rad51 protein. Nucleic Acids Res (1997) 1.43
Alternatively spliced forms in the carboxy-terminal domain of the p53 protein regulate its ability to promote annealing of complementary single strands of nucleic acids. Mol Cell Biol (1995) 1.43
Functional domains of wild-type and mutant p53 proteins involved in transcriptional regulation, transdominant inhibition, and transformation suppression. Mol Cell Biol (1993) 1.42
Repression of endogenous p53 transactivation function in HeLa cervical carcinoma cells by human papillomavirus type 16 E6, human mdm-2, and mutant p53. J Virol (1993) 1.42
Interaction of p53 with its consensus DNA-binding site. Mol Cell Biol (1995) 1.40
Gain-of-function mutations of the p53 gene induce lymphohematopoietic metastatic potential and tissue invasiveness. Am J Pathol (1994) 1.39
Differential regulation of plasminogen activator and inhibitor gene transcription by the tumor suppressor p53. Nucleic Acids Res (1995) 1.37
Adenovirus E1B 55K represses p53 activation in vitro. J Virol (1998) 1.37
Dial 9-1-1 for p53: mechanisms of p53 activation by cellular stress. Neoplasia (2000) 1.36
Regulation of p53-dependent apoptosis, transcriptional repression, and cell transformation by phosphorylation of the 55-kilodalton E1B protein of human adenovirus type 5. J Virol (1997) 1.35
Physical and functional interaction between wild-type p53 and mdm2 proteins. Mol Cell Biol (1994) 1.34
Proteolysis by calpains: a possible contribution to degradation of p53. Mol Cell Biol (1997) 1.30
Merkel cell polyomavirus large T antigen disrupts host genomic integrity and inhibits cellular proliferation. J Virol (2013) 1.28
p53 induction is associated with neuronal damage in the central nervous system. Proc Natl Acad Sci U S A (1994) 1.27
p300 family members associate with the carboxyl terminus of simian virus 40 large tumor antigen. J Virol (1997) 1.27
p53 inhibits RNA polymerase III-directed transcription in a promoter-dependent manner. Mol Cell Biol (1996) 1.26
Adenovirus E1B 55-kilodalton oncoprotein inhibits p53 acetylation by PCAF. Mol Cell Biol (2000) 1.25
Tight DNA binding and oligomerization are dispensable for the ability of p53 to transactivate target genes and suppress transformation. EMBO J (1993) 1.25
Distinct residues of human p53 implicated in binding to DNA, simian virus 40 large T antigen, 53BP1, and 53BP2. Mol Cell Biol (1994) 1.24
The p53 circuit board. Biochim Biophys Acta (2012) 1.24
Regulation of apoptosis in transgenic mice by simian virus 40 T antigen-mediated inactivation of p53. Proc Natl Acad Sci U S A (1994) 1.24
The amino-terminal functions of the simian virus 40 large T antigen are required to overcome wild-type p53-mediated growth arrest of cells. J Virol (1994) 1.22
Focal adhesion kinase and p53 signal transduction pathways in cancer. Front Biosci (Landmark Ed) (2010) 1.20
Phosphorylation at the carboxy terminus of the 55-kilodalton adenovirus type 5 E1B protein regulates transforming activity. J Virol (1994) 1.20
Mutation in the bimD gene of Aspergillus nidulans confers a conditional mitotic block and sensitivity to DNA damaging agents. Genetics (1993) 1.20
Cul7/p185/p193 binding to simian virus 40 large T antigen has a role in cellular transformation. J Virol (2004) 1.19
Wild-type alternatively spliced p53: binding to DNA and interaction with the major p53 protein in vitro and in cells. EMBO J (1994) 1.16
Tumourigenesis associated with the p53 tumour suppressor gene. Br J Cancer (1993) 1.16
Identification of a novel p53 promoter element involved in genotoxic stress-inducible p53 gene expression. Mol Cell Biol (1995) 1.16
Transcriptional activation of the human proliferating-cell nuclear antigen promoter by p53. Proc Natl Acad Sci U S A (1996) 1.15
Modulation of the transcriptional activity of thyroid hormone receptors by the tumor suppressor p53. Proc Natl Acad Sci U S A (1996) 1.15
Induction of wild-type p53 activity in human cancer cells by ribozymes that repair mutant p53 transcripts. Proc Natl Acad Sci U S A (2000) 1.15
Interference with p53 protein inhibits hematopoietic and muscle differentiation. J Cell Biol (1996) 1.15
Proapoptotic BAX and BAK control multiple initiator caspases. EMBO Rep (2005) 1.13
Mutation of the casein kinase II phosphorylation site abolishes the anti-proliferative activity of p53. Nucleic Acids Res (1992) 1.12
Gene regulation by temperature-sensitive p53 mutants: identification of p53 response genes. Proc Natl Acad Sci U S A (1994) 1.11
Analysis of a protein-binding domain of p53. Mol Cell Biol (1993) 1.10
Metabolic control of G1-S transition: cyclin E degradation by p53-induced activation of the ubiquitin-proteasome system. J Cell Biol (2010) 1.10
Negative regulation of transcription in eukaryotes. Biochem J (1993) 1.10
Transcriptional repression by p53 involves molecular interactions distinct from those with the TATA box binding protein. Nucleic Acids Res (1996) 1.08
The p53 tumor suppressor protein regulates hematopoietic stem cell fate. J Cell Physiol (2011) 1.08
Endogenous p53 protein generated from wild-type alternatively spliced p53 RNA in mouse epidermal cells. Mol Cell Biol (1994) 1.08
The tumor suppressor p53 regulates its own transcription. Mol Cell Biol (1993) 1.08
Reversal of in vitro p53 squelching by both TFIIB and TFIID. Mol Cell Biol (1995) 1.05
Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis. Cell (1998) 16.08
Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta. Nature (2000) 13.45
p53: puzzle and paradigm. Genes Dev (1996) 13.16
IKK-1 and IKK-2: cytokine-activated IkappaB kinases essential for NF-kappaB activation. Science (1997) 11.89
Enhanced phosphorylation of p53 by ATM in response to DNA damage. Science (1998) 10.89
DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2. Cell (1997) 10.52
Complete genome sequence of an M1 strain of Streptococcus pyogenes. Proc Natl Acad Sci U S A (2001) 9.40
ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs. Mol Cell (2000) 9.13
Genetic inheritance of gene expression in human cell lines. Am J Hum Genet (2004) 8.97
Induction of apoptosis in fibroblasts by IL-1 beta-converting enzyme, a mammalian homolog of the C. elegans cell death gene ced-3. Cell (1993) 7.16
RAGE and amyloid-beta peptide neurotoxicity in Alzheimer's disease. Nature (1996) 7.04
Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGF beta receptor for degradation. Mol Cell (2000) 6.69
Identification of p53 as a sequence-specific DNA-binding protein. Science (1991) 6.60
Cell-free translation of simian virus 40 early messenger RNA coding for viral T-antigen. Proc Natl Acad Sci U S A (1977) 6.57
A role for ATR in the DNA damage-induced phosphorylation of p53. Genes Dev (1999) 6.34
The human homologs of checkpoint kinases Chk1 and Cds1 (Chk2) phosphorylate p53 at multiple DNA damage-inducible sites. Genes Dev (2000) 5.72
Ich-1, an Ice/ced-3-related gene, encodes both positive and negative regulators of programmed cell death. Cell (1994) 5.25
Somatic mutations of the mitochondrial genome in human colorectal tumours. Nat Genet (1998) 4.67
E1A signaling to p53 involves the p19(ARF) tumor suppressor. Genes Dev (1998) 4.60
Activation of ATF6 and an ATF6 DNA binding site by the endoplasmic reticulum stress response. J Biol Chem (2000) 4.37
Inducible binding of a factor to the c-fos enhancer. Cell (1986) 3.98
p53 levels, functional domains, and DNA damage determine the extent of the apoptotic response of tumor cells. Genes Dev (1996) 3.98
Synapse-specific, long-term facilitation of aplysia sensory to motor synapses: a function for local protein synthesis in memory storage. Cell (1997) 3.93
Murine caspase-11, an ICE-interacting protease, is essential for the activation of ICE. Cell (1998) 3.62
Effects of p21(Cip1/Waf1) at both the G1/S and the G2/M cell cycle transitions: pRb is a critical determinant in blocking DNA replication and in preventing endoreduplication. Mol Cell Biol (1998) 3.61
Wild-type but not mutant p53 immunopurified proteins bind to sequences adjacent to the SV40 origin of replication. Cell (1991) 3.59
Transcriptional regulation by p53: one protein, many possibilities. Cell Death Differ (2006) 3.53
c-fos sequence necessary for basal expression and induction by epidermal growth factor, 12-O-tetradecanoyl phorbol-13-acetate and the calcium ionophore. Mol Cell Biol (1987) 3.52
Human cytomegalovirus with IE-2 (UL122) deleted fails to express early lytic genes. J Virol (2001) 3.50
Drosophila p53 is a structural and functional homolog of the tumor suppressor p53. Cell (2000) 3.41
Wild-type p53 mediates positive regulation of gene expression through a specific DNA sequence element. Genes Dev (1992) 3.37
PML is induced by oncogenic ras and promotes premature senescence. Genes Dev (2000) 3.35
Regulation of cardiac gene expression during myocardial growth and hypertrophy: molecular studies of an adaptive physiologic response. FASEB J (1991) 3.29
The murine p53 protein blocks replication of SV40 DNA in vitro by inhibiting the initiation functions of SV40 large T antigen. Cell (1989) 3.01
Human magnetic resonance imaging at 8 T. NMR Biomed (1998) 2.96
Mutations of the UMOD gene are responsible for medullary cystic kidney disease 2 and familial juvenile hyperuricaemic nephropathy. J Med Genet (2002) 2.90
Monoclonal antibodies against oxidized low-density lipoprotein bind to apoptotic cells and inhibit their phagocytosis by elicited macrophages: evidence that oxidation-specific epitopes mediate macrophage recognition. Proc Natl Acad Sci U S A (1999) 2.85
Effect of RF coil excitation on field inhomogeneity at ultra high fields: a field optimized TEM resonator. Magn Reson Imaging (2001) 2.84
Monoclonal autoantibodies specific for oxidized phospholipids or oxidized phospholipid-protein adducts inhibit macrophage uptake of oxidized low-density lipoproteins. J Clin Invest (1999) 2.81
IL-18-stimulated GADD45 beta required in cytokine-induced, but not TCR-induced, IFN-gamma production. Nat Immunol (2001) 2.81
Reconstitution of human epidermal growth factor receptors and its deletion mutants in cultured hamster cells. J Biol Chem (1986) 2.78
Human p53 is phosphorylated by p60-cdc2 and cyclin B-cdc2. Proc Natl Acad Sci U S A (1990) 2.77
A transient, neuron-wide form of CREB-mediated long-term facilitation can be stabilized at specific synapses by local protein synthesis. Cell (1999) 2.77
Differential affinities of simian virus 40 large tumor antigen for DNA. Proc Natl Acad Sci U S A (1980) 2.75
Identification of redox/repair protein Ref-1 as a potent activator of p53. Genes Dev (1997) 2.70
A subset of tumor-derived mutant forms of p53 down-regulate p63 and p73 through a direct interaction with the p53 core domain. Mol Cell Biol (2001) 2.69
IkappaB kinase (IKK)-associated protein 1, a common component of the heterogeneous IKK complex. Mol Cell Biol (1999) 2.68
A senescence-like phenotype distinguishes tumor cells that undergo terminal proliferation arrest after exposure to anticancer agents. Cancer Res (1999) 2.67
Sequences of the A-MuLV protein needed for fibroblast and lymphoid cell transformation. Cell (1983) 2.54
The Peutz-Jegher gene product LKB1 is a mediator of p53-dependent cell death. Mol Cell (2001) 2.53
A proteolytic fragment from the central region of p53 has marked sequence-specific DNA-binding activity when generated from wild-type but not from oncogenic mutant p53 protein. Genes Dev (1993) 2.53
MAP kinase translocates into the nucleus of the presynaptic cell and is required for long-term facilitation in Aplysia. Neuron (1997) 2.50
DNA damage-inducible phosphorylation of p53 at N-terminal sites including a novel site, Ser20, requires tetramerization. EMBO J (1999) 2.50
TG101209, a small molecule JAK2-selective kinase inhibitor potently inhibits myeloproliferative disorder-associated JAK2V617F and MPLW515L/K mutations. Leukemia (2007) 2.49
Increased and altered DNA binding of human p53 by S and G2/M but not G1 cyclin-dependent kinases. Nature (1995) 2.47
Benzyloxycarbonyl-Val-Ala-Asp (OMe) fluoromethylketone (Z-VAD.FMK) inhibits apoptosis by blocking the processing of CPP32. Biochem J (1996) 2.46
Receptor-dependent cell stress and amyloid accumulation in systemic amyloidosis. Nat Med (2000) 2.44
An intracellular protein that binds amyloid-beta peptide and mediates neurotoxicity in Alzheimer's disease. Nature (1997) 2.42
p73 function is inhibited by tumor-derived p53 mutants in mammalian cells. Mol Cell Biol (1999) 2.41
Estrogen receptor alpha, not beta, is a critical link in estradiol-mediated protection against brain injury. Proc Natl Acad Sci U S A (2001) 2.40
High mobility group protein-1 (HMG-1) is a unique activator of p53. Genes Dev (1998) 2.40
Mutations in the cytoplasmic domain of EGF receptor affect EGF binding and receptor internalization. EMBO J (1986) 2.38
Role of p53 and p21waf1/cip1 in senescence-like terminal proliferation arrest induced in human tumor cells by chemotherapeutic drugs. Oncogene (1999) 2.34
Transcriptional regulation during cardiac growth and development. Annu Rev Physiol (1993) 2.33
Pro-proliferative FoxM1 is a target of p53-mediated repression. Oncogene (2009) 2.32
Site-specific binding of wild-type p53 to cellular DNA is inhibited by SV40 T antigen and mutant p53. Genes Dev (1992) 2.29
The Jerusalem perinatal study. 1. Design and organization of a continuing, community-based, record-linked survey. Isr J Med Sci (1970) 2.24
Infrared spectroscopy of human tissue. V. Infrared spectroscopic studies of myeloid leukemia (ML-1) cells at different phases of the cell cycle. Biospectroscopy (1999) 2.23
Casein kinase II enhances the DNA binding activity of serum response factor. Genes Dev (1990) 2.23
Apoptosis of T cells mediated by Ca2+-induced release of the transcription factor MEF2. Science (1999) 2.17
Species-specific in vitro synthesis of DNA containing the polyoma virus origin of replication. Proc Natl Acad Sci U S A (1986) 2.16
Activation of p53 sequence-specific DNA binding by short single strands of DNA requires the p53 C-terminus. Cell (1995) 2.13
Nitric-oxide dioxygenase activity and function of flavohemoglobins. sensitivity to nitric oxide and carbon monoxide inhibition. J Biol Chem (2000) 2.13
The p53 protein is an unusually shaped tetramer that binds directly to DNA. Proc Natl Acad Sci U S A (1993) 2.11
Identification of a full-length cDNA for an endogenous retrovirus of miniature swine. J Virol (1998) 2.10
The 400 kDa subunit of the PCAF histone acetylase complex belongs to the ATM superfamily. Mol Cell (1998) 2.08
Premedication with intravenous dexmedetomidine-midazolam suppresses fentanyl-induced cough. Ir J Med Sci (2012) 2.06
The sarcomeric actin CArG-binding factor is indistinguishable from the c-fos serum response factor. Mol Cell Biol (1989) 2.05
Loss of in vitro metal ion binding specificity in mutant copper-zinc superoxide dismutases associated with familial amyotrophic lateral sclerosis. J Biol Chem (2000) 2.05
Identification and characterization of Ich-3, a member of the interleukin-1beta converting enzyme (ICE)/Ced-3 family and an upstream regulator of ICE. J Biol Chem (1996) 2.05
cAMP response element-binding protein is activated by Ca2+/calmodulin- as well as cAMP-dependent protein kinase. Proc Natl Acad Sci U S A (1991) 2.04
Geographical and ethnic variation of the 677C>T allele of 5,10 methylenetetrahydrofolate reductase (MTHFR): findings from over 7000 newborns from 16 areas world wide. J Med Genet (2003) 2.03
Validation of lucigenin (bis-N-methylacridinium) as a chemilumigenic probe for detecting superoxide anion radical production by enzymatic and cellular systems. J Biol Chem (1998) 1.99
A mutant p53 that discriminates between p53-responsive genes cannot induce apoptosis. Mol Cell Biol (1996) 1.98
Are interactions with p63 and p73 involved in mutant p53 gain of oncogenic function? Oncogene (2007) 1.97
Interaction of ATF6 and serum response factor. Mol Cell Biol (1997) 1.96
Mutant p53 proteins bind DNA abnormally in vitro. Oncogene (1991) 1.96
p53 down-regulates CHK1 through p21 and the retinoblastoma protein. Mol Cell Biol (2001) 1.93
Donepezil therapy in clinical practice: a randomized crossover study. Arch Neurol (2000) 1.93
Regulatory role of MEF2D in serum induction of the c-jun promoter. Mol Cell Biol (1995) 1.93
Beta-COP is essential for transport of protein from the endoplasmic reticulum to the Golgi in vitro. J Cell Biol (1993) 1.88
Ca(2+)-dependent gene expression mediated by MEF2 transcription factors. J Biol Chem (2000) 1.86
A small subclass of SV40 T antigen binds to the viral origin of replication. Cell (1982) 1.86
Interaction between the adhesion receptor, CD44, and the oncogene product, p185HER2, promotes human ovarian tumor cell activation. J Biol Chem (1997) 1.86
Human cytomagalovirus IE1 and IE2 proteins are mutagenic and mediate "hit-and-run" oncogenic transformation in cooperation with the adenovirus E1A proteins. Proc Natl Acad Sci U S A (1997) 1.85
Amyloid-beta peptide-receptor for advanced glycation endproduct interaction elicits neuronal expression of macrophage-colony stimulating factor: a proinflammatory pathway in Alzheimer disease. Proc Natl Acad Sci U S A (1997) 1.82