Published in J Hum Genet on January 01, 2000
Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors. Science (1998) 21.13
The complete nucleotide sequence of the tobacco chloroplast genome: its gene organization and expression. EMBO J (1986) 19.59
Rapid and sensitive detection of point mutations and DNA polymorphisms using the polymerase chain reaction. Genomics (1989) 19.10
The genome of the social amoeba Dictyostelium discoideum. Nature (2005) 9.18
A highly sensitive method to assay FK-506 levels in plasma. Transplant Proc (1987) 8.45
E-CELL: software environment for whole-cell simulation. Bioinformatics (1999) 6.29
A precise and fast temperature mapping using water proton chemical shift. Magn Reson Med (1995) 5.73
Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. Gene (1994) 5.28
Comparison of complete amino acid sequences and receptor-binding properties among 13 serotypes of hemagglutinins of influenza A viruses. Virology (1991) 4.85
Calyculin A and okadaic acid: inhibitors of protein phosphatase activity. Biochem Biophys Res Commun (1989) 4.63
Genetic analysis of blood pressure in spontaneously hypertensive rats. Jpn Circ J (1970) 4.59
Chloramphenicol-, dihydrostreptomycin-, and kanamycin-inactivating enzymes from multiple drug-resistant Escherichia coli carrying episome 'R'. Nature (1965) 4.53
Identification and characterization of the potential promoter regions of 1031 kinds of human genes. Genome Res (2001) 4.03
Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. Gene (1997) 4.02
Identification of a point mutation in the catalytic domain of the protooncogene c-kit in peripheral blood mononuclear cells of patients who have mastocytosis with an associated hematologic disorder. Proc Natl Acad Sci U S A (1995) 3.85
Large voltage-induced magnetic anisotropy change in a few atomic layers of iron. Nat Nanotechnol (2009) 3.75
Association of the encapsulation of Bacillus anthracis with a 60 megadalton plasmid. J Gen Microbiol (1985) 3.64
The DNA sequence of Bombyx mori fibroin gene including the 5' flanking, mRNA coding, entire intervening and fibroin protein coding regions. Cell (1979) 3.60
Proliferative activity of intratumoral CD8(+) T-lymphocytes as a prognostic factor in human renal cell carcinoma: clinicopathologic demonstration of antitumor immunity. Cancer Res (2001) 3.51
Transformation by Rous sarcoma virus induces a novel gene with homology to a mitogenic platelet protein. Cell (1987) 3.50
Diverse transcriptional initiation revealed by fine, large-scale mapping of mRNA start sites. EMBO Rep (2001) 3.47
Interferon beta prevents recurrence of hepatocellular carcinoma after complete resection or ablation of the primary tumor-A prospective randomized study of hepatitis C virus-related liver cancer. Hepatology (2000) 3.42
Mini-laparoscopic appendectomy using a needle loop retractor offers optimal cosmetic results. Surg Endosc (2004) 3.38
IFNβ-1b may severely exacerbate Japanese optic-spinal MS in neuromyelitis optica spectrum. Neurology (2010) 3.34
Success and virulence in Toxoplasma as the result of sexual recombination between two distinct ancestries. Science (2001) 3.21
Structural analysis of the fibroin gene at the 5' end and its surrounding regions. Cell (1979) 3.16
Accelerated transport and maturation of lysosomal alpha-galactosidase A in Fabry lymphoblasts by an enzyme inhibitor. Nat Med (1999) 3.11
Receptor specificity of influenza A viruses correlates with the agglutination of erythrocytes from different animal species. Virology (1997) 3.10
Evolutionary motif and its biological and structural significance. J Mol Evol (1997) 3.03
A new malformation syndrome of long palpebral fissures, large ears, depressed nasal tip, and skeletal anomalies associated with postnatal dwarfism and mental retardation. J Pediatr (1981) 2.97
Association of CD4+ T cell-dependent, interferon-gamma-mediated necrosis of the small intestine with genetic susceptibility of mice to peroral infection with Toxoplasma gondii. J Exp Med (1996) 2.97
Presynaptic inhibition caused by retrograde signal from metabotropic glutamate to cannabinoid receptors. Neuron (2001) 2.94
Human centromere protein A (CENP-A) can replace histone H3 in nucleosome reconstitution in vitro. Proc Natl Acad Sci U S A (2000) 2.91
Initiation of simian virus 40 DNA replication in vitro. J Virol (1983) 2.88
Complete nucleotide sequence and genetic organization of Aichi virus, a distinct member of the Picornaviridae associated with acute gastroenteritis in humans. J Virol (1998) 2.85
Familial gastrointestinal stromal tumours with germline mutation of the KIT gene. Nat Genet (1998) 2.80
Molecular cloning of a novel human CC chemokine EBI1-ligand chemokine that is a specific functional ligand for EBI1, CCR7. J Biol Chem (1997) 2.79
Early-onset ataxia with ocular motor apraxia and hypoalbuminemia is caused by mutations in a new HIT superfamily gene. Nat Genet (2001) 2.79
Development of a compact computed tomographic apparatus for dental use. Dentomaxillofac Radiol (1999) 2.79
Efficient gene activation in mammalian cells by using recombinant adenovirus expressing site-specific Cre recombinase. Nucleic Acids Res (1995) 2.79
Emergence and takeover of YMDD motif mutant hepatitis B virus during long-term lamivudine therapy and re-takeover by wild type after cessation of therapy. Hepatology (1998) 2.67
A human gene responsible for Zellweger syndrome that affects peroxisome assembly. Science (1992) 2.63
Occurrence of tetrodotoxin and anhydrotetrodotoxin in Vibrio sp. isolated from the intestines of a xanthid crab, Atergatis floridus. J Biochem (1986) 2.56
Molecular cloning of a novel human CC chemokine secondary lymphoid-tissue chemokine that is a potent chemoattractant for lymphocytes and mapped to chromosome 9p13. J Biol Chem (1997) 2.51
Monensin and FCCP inhibit the intracellular transport of alphavirus membrane glycoproteins. J Cell Biol (1980) 2.50
Globoid cell leucodystrophy (Krabbe's disease): deficiency of galactocerebroside beta-galactosidase. Proc Natl Acad Sci U S A (1970) 2.48
Phage particle-mediated gene transfer to cultured mammalian cells. Mol Cell Biol (1982) 2.47
Correlation between the presence of a fifty-megadalton plasmid in Salmonella dublin and virulence for mice. Infect Immun (1983) 2.46
Human intelectin is a novel soluble lectin that recognizes galactofuranose in carbohydrate chains of bacterial cell wall. J Biol Chem (2001) 2.45
Neurologic improvement after peripheral blood stem cell transplantation in POEMS syndrome. Neurology (2008) 2.45
Faithful transcription initiation of fibroin gene in a homologous cell-free system reveals an enhancing effect of 5' flanking sequence far upstream. Cell (1981) 2.42
Differences in sialic acid-galactose linkages in the chicken egg amnion and allantois influence human influenza virus receptor specificity and variant selection. J Virol (1997) 2.38
Daily walking combined with diet therapy is a useful means for obese NIDDM patients not only to reduce body weight but also to improve insulin sensitivity. Diabetes Care (1995) 2.33
Organization of rRNA genes in Mycobacterium bovis BCG. J Bacteriol (1987) 2.33
Induction of cytotoxicity by photoexcited TiO2 particles. Cancer Res (1992) 2.31
The enzymatic acetylation of chloramphenicol by the multiple drug-resistant Escherichia coli carrying R factor. J Biol Chem (1967) 2.31
Eccrine adenocarcinoma. A clinicopathologic study of 35 cases. Arch Dermatol (1983) 2.30
The genes for silk fibroin in Bombyx mori. J Mol Biol (1972) 2.29
Disease progression and hepatocellular carcinogenesis in patients with chronic viral hepatitis: a prospective observation of 2215 patients. J Hepatol (1998) 2.21
Application of a reverse transcription-PCR for identification and differentiation of Aichi virus, a new member of the Picornavirus family associated with gastroenteritis in humans. J Clin Microbiol (2000) 2.19
Restraining infarct expansion preserves left ventricular geometry and function after acute anteroapical infarction. Circulation (1999) 2.19
Factors predictive of survival among 337 patients with mesothelioma treated between 1984 and 1994 by the Cancer and Leukemia Group B. Chest (1998) 2.18
Heptakis(2,6-O-dimethyl)beta-cyclodextrin: a novel growth stimulant for Bordetella pertussis phase I. J Clin Microbiol (1983) 2.17
Validation study of the in vitro micronucleus test in a Chinese hamster lung cell line (CHL/IU). Mutagenesis (1999) 2.16
Induction of the cytokine signal regulator SOCS3/CIS3 as a therapeutic strategy for treating inflammatory arthritis. J Clin Invest (2001) 2.15
Use of the human elongation factor 1 alpha promoter as a versatile and efficient expression system. Gene (1990) 2.14
Pulmonary fibrosis in asbestos insulation workers with lung cancer: a radiological and histopathological evaluation. Br J Ind Med (1987) 2.14
Ectodomain shedding of epidermal growth factor receptor ligands is required for keratinocyte migration in cutaneous wound healing. J Cell Biol (2000) 2.14
Transcriptional regulation of the cyclin D1 promoter by STAT5: its involvement in cytokine-dependent growth of hematopoietic cells. EMBO J (1999) 2.10
mGluR1 in cerebellar Purkinje cells essential for long-term depression, synapse elimination, and motor coordination. Science (2000) 2.09
Statistical analysis of the 5' untranslated region of human mRNA using "Oligo-Capped" cDNA libraries. Genomics (2000) 2.09
Effect of heptakis (2,6-O-dimethyl) beta-cyclodextrin on the production of pertussis toxin by Bordetella pertussis. Infect Immun (1983) 2.06
Is white coat hypertension innocent? Structure and function of the heart in the elderly. Hypertension (1993) 1.99
Incidence of primary cholangiocellular carcinoma of the liver in japanese patients with hepatitis C virus-related cirrhosis. Cancer (2000) 1.98
The diagnosis of a DRESS syndrome has been sufficiently established on the basis of typical clinical features and viral reactivations. Br J Dermatol (2007) 1.97
Mutations in mitochondrial control region DNA in gastric tumours of Japanese patients. Eur J Cancer (1999) 1.94
Motor discoordination and increased susceptibility to cerebellar injury in GLAST mutant mice. Eur J Neurosci (1998) 1.90
Rfc5, a small subunit of replication factor C complex, couples DNA replication and mitosis in budding yeast. Proc Natl Acad Sci U S A (1996) 1.89
Intercellular spaces of the human epidermis as demonstrated with lanthanum. J Invest Dermatol (1971) 1.89
Promoter sequence of fibroin gene assigned by in vitro transcription system. Proc Natl Acad Sci U S A (1981) 1.87
Identification of hypoxia-inducible factor 1 ancillary sequence and its function in vascular endothelial growth factor gene induction by hypoxia and nitric oxide. J Biol Chem (2000) 1.86
Molecular cloning of a novel human CC chemokine liver and activation-regulated chemokine (LARC) expressed in liver. Chemotactic activity for lymphocytes and gene localization on chromosome 2. J Biol Chem (1997) 1.84
Marine bacteria which produce tetrodotoxin. Appl Environ Microbiol (1987) 1.84
Changes in bradykinin level in coronary sinus blood after the experimental occlusion of a coronary artery. Am Heart J (1973) 1.83
Comet 81P/Wild 2 under a microscope. Science (2006) 1.83
Stevens-Johnson syndrome induced by methazolamide treatment. Arch Ophthalmol (1997) 1.83
The dwarf-1 (dt) Mutant of Zea mays blocks three steps in the gibberellin-biosynthetic pathway. Proc Natl Acad Sci U S A (1996) 1.80
Basis of chloramphenicol resistance in naturally isolated resistant staphylococci. J Bacteriol (1966) 1.80
Isolation and identification of the messenger RNA for silk fibroin from Bombyx mori. J Mol Biol (1972) 1.79
Mucopolysaccharidosis type IVA (Morquio A disease): clinical review and current treatment. Curr Pharm Biotechnol (2011) 1.78
Amino acid residues contributing to the substrate specificity of the influenza A virus neuraminidase. J Virol (1999) 1.78
Identification of a novel gene, GASC1, within an amplicon at 9p23-24 frequently detected in esophageal cancer cell lines. Cancer Res (2000) 1.78
Effect of AT877 on cerebral vasospasm after aneurysmal subarachnoid hemorrhage. Results of a prospective placebo-controlled double-blind trial. J Neurosurg (1992) 1.77
Primary hepatic lymphoma associated with primary biliary cirrhosis. Am J Gastroenterol (1999) 1.77
Activation of calmodulin by various metal cations as a function of ionic radius. Mol Pharmacol (1984) 1.77
Mouse ULK2, a novel member of the UNC-51-like protein kinases: unique features of functional domains. Oncogene (1999) 1.76
Decreased resistance of B cell-deficient mice to infection with Toxoplasma gondii despite unimpaired expression of IFN-gamma, TNF-alpha, and inducible nitric oxide synthase. J Immunol (2000) 1.75