Crystal structure of the caspase activator human granzyme B, a proteinase highly specific for an Asp-P1 residue.

PubWeight™: 0.88‹?›

🔗 View Article (PMID 11209755)

Published in Biol Chem on December 01, 2000

Authors

E Estébanez-Perpiña1, P Fuentes-Prior, D Belorgey, M Braun, R Kiefersauer, K Maskos, R Huber, H Rubin, W Bode

Author Affiliations

1: Abteilung für Strukturforschung, Max-Planck-Institut für Biochemie, Planegg-Martinsried, Germany.

Articles by these authors

The complete genome sequence of the gram-positive bacterium Bacillus subtilis. Nature (1997) 33.47

Crystal structure of the 20S proteasome from the archaeon T. acidophilum at 3.4 A resolution. Science (1995) 12.94

Structure of 20S proteasome from yeast at 2.4 A resolution. Nature (1997) 12.73

X-ray structure analysis of a membrane protein complex. Electron density map at 3 A resolution and a model of the chromophores of the photosynthetic reaction center from Rhodopseudomonas viridis. J Mol Biol (1984) 8.85

The complete genome of the hyperthermophilic bacterium Aquifex aeolicus. Nature (1998) 7.77

A gated channel into the proteasome core particle. Nat Struct Biol (2000) 5.42

Structure of the protein subunits in the photosynthetic reaction centre of Rhodopseudomonas viridis at 3Å resolution. Nature (2012) 5.22

Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Nature (1999) 5.03

The nucleic acid of the Bryan strain of Rous sarcoma virus: purification of the virus and isolation of the nucleic acid. Proc Natl Acad Sci U S A (1965) 4.95

Mutations in GPC3, a glypican gene, cause the Simpson-Golabi-Behmel overgrowth syndrome. Nat Genet (1996) 4.62

The refined 1.9 A crystal structure of human alpha-thrombin: interaction with D-Phe-Pro-Arg chloromethylketone and significance of the Tyr-Pro-Pro-Trp insertion segment. EMBO J (1989) 4.49

Fourier Domain Mode Locking (FDML): A new laser operating regime and applications for optical coherence tomography. Opt Express (2006) 4.49

The structures of HsIU and the ATP-dependent protease HsIU-HsIV. Nature (2000) 4.46

Structure of bovine pancreatic trypsin inhibitor. Results of joint neutron and X-ray refinement of crystal form II. J Mol Biol (1984) 4.14

Effects of local cell concentrations upon the growth of chick embryo cells in tissue culture. Exp Cell Res (1968) 3.94

Proteasome from Thermoplasma acidophilum: a threonine protease. Science (1995) 3.62

Human alpha 1-proteinase inhibitor. Crystal structure analysis of two crystal modifications, molecular model and preliminary analysis of the implications for function. J Mol Biol (1984) 3.60

The 3.2-A crystal structure of the human IgG1 Fc fragment-Fc gammaRIII complex. Nature (2000) 3.53

Density dependent inhibition of cell growth in culture. Nature (1967) 3.51

Crystallographic refinement and atomic models of two different forms of citrate synthase at 2.7 and 1.7 A resolution. J Mol Biol (1982) 3.28

Natural protein proteinase inhibitors and their interaction with proteinases. Eur J Biochem (1992) 3.27

Structural analysis of human IgG-Fc glycoforms reveals a correlation between glycosylation and structural integrity. J Mol Biol (2003) 3.25

Crystallographic refinement and atomic models of the intact immunoglobulin molecule Kol and its antigen-binding fragment at 3.0 A and 1.0 A resolution. J Mol Biol (1980) 3.25

Release from density dependent growth inhibition by proteolytic enzymes. Nature (1970) 3.20

Structure of the complex formed by bovine trypsin and bovine pancreatic trypsin inhibitor. II. Crystallographic refinement at 1.9 A resolution. J Mol Biol (1974) 3.17

The proteasome. Annu Rev Biophys Biomol Struct (1999) 3.13

Crystallographic structure studies of an IgG molecule and an Fc fragment. Nature (1976) 3.00

Characterization of a human preadipocyte cell strain with high capacity for adipose differentiation. Int J Obes Relat Metab Disord (2001) 2.94

Crystal structure of the thermosome, the archaeal chaperonin and homolog of CCT. Cell (1998) 2.94

Temperature-dependent alterations in sugar transport in cells infected by a temperature-sensitive mutant of Rous sarcoma virus. Proc Natl Acad Sci U S A (1971) 2.83

Structure of the tetrameric restriction endonuclease NgoMIV in complex with cleaved DNA. Nat Struct Biol (2000) 2.82

The stringent response of Mycobacterium tuberculosis is required for long-term survival. J Bacteriol (2000) 2.80

Crystal structure of a carbon monoxide dehydrogenase reveals a [Ni-4Fe-5S] cluster. Science (2001) 2.78

The structure of a complex of recombinant hirudin and human alpha-thrombin. Science (1990) 2.71

Structure and mechanism of the aberrant ba(3)-cytochrome c oxidase from thermus thermophilus. EMBO J (2000) 2.71

Role of the J-domain in the cooperation of Hsp40 with Hsp70. Proc Natl Acad Sci U S A (1998) 2.66

Structure determination and refinement of human alpha class glutathione transferase A1-1, and a comparison with the Mu and Pi class enzymes. J Mol Biol (1993) 2.66

Behavioral engineering: postural control by a portable operant apparatus. J Appl Behav Anal (1968) 2.65

The metzincins--topological and sequential relations between the astacins, adamalysins, serralysins, and matrixins (collagenases) define a superfamily of zinc-peptidases. Protein Sci (1995) 2.63

Phosphotransferase and substrate binding mechanism of the cAMP-dependent protein kinase catalytic subunit from porcine heart as deduced from the 2.0 A structure of the complex with Mn2+ adenylyl imidodiphosphate and inhibitor peptide PKI(5-24). EMBO J (1993) 2.54

A late Neanderthal associated with Upper Palaeolithic artefacts. Nature (1996) 2.53

Human C1 inhibitor: primary structure, cDNA cloning, and chromosomal localization. Biochemistry (1986) 2.52

Intensive care unit telemedicine: alternate paradigm for providing continuous intensivist care. Crit Care Med (2000) 2.50

Calcium protects DNase I from proteinase K: a new method for the removal of contaminating RNase from DNase I. Anal Biochem (1980) 2.49

Amplified, frequency swept lasers for frequency domain reflectometry and OCT imaging: design and scaling principles. Opt Express (2005) 2.48

The 2.0 A X-ray crystal structure of chicken egg white cystatin and its possible mode of interaction with cysteine proteinases. EMBO J (1988) 2.48

Primary structure of human neutrophil elastase. Proc Natl Acad Sci U S A (1987) 2.45

Arabidopsis thaliana Rop GTPases are localized to tips of root hairs and control polar growth. EMBO J (2001) 2.44

The refined 2.4 A X-ray crystal structure of recombinant human stefin B in complex with the cysteine proteinase papain: a novel type of proteinase inhibitor interaction. EMBO J (1990) 2.44

High-level biosynthetic substitution of methionine in proteins by its analogs 2-aminohexanoic acid, selenomethionine, telluromethionine and ethionine in Escherichia coli. Eur J Biochem (1995) 2.44

X-ray crystallographic structure of the light-harvesting biliprotein C-phycocyanin from the thermophilic cyanobacterium Mastigocladus laminosus and its resemblance to globin structures. J Mol Biol (1985) 2.42

Crystal structure of P22 tailspike protein: interdigitated subunits in a thermostable trimer. Science (1994) 2.41

Root hair formation: F-actin-dependent tip growth is initiated by local assembly of profilin-supported F-actin meshworks accumulated within expansin-enriched bulges. Dev Biol (2000) 2.37

The blue oxidases, ascorbate oxidase, laccase and ceruloplasmin. Modelling and structural relationships. Eur J Biochem (1990) 2.37

X-ray crystal structures of cytosolic glutathione S-transferases. Implications for protein architecture, substrate recognition and catalytic function. Eur J Biochem (1994) 2.37

The three-dimensional structure of class pi glutathione S-transferase in complex with glutathione sulfonate at 2.3 A resolution. EMBO J (1991) 2.36

Organic anion-transporting polypeptide B (OATP-B) and its functional comparison with three other OATPs of human liver. Gastroenterology (2001) 2.36

Enumeration of bacteria forming acetate from H2 and CO2 in anaerobic habitats. Arch Microbiol (1979) 2.36

The cystatins: protein inhibitors of cysteine proteinases. FEBS Lett (1991) 2.33

The refined crystal structure of bovine beta-trypsin at 1.8 A resolution. II. Crystallographic refinement, calcium binding site, benzamidine binding site and active site at pH 7.0. J Mol Biol (1975) 2.24

The mechanism of interference between an avian leukosis virus and Rous sarcoma virus. I. Establishment of interference. Virology (1966) 2.22

Crystal structure analysis of oxidized Pseudomonas aeruginosa azurin at pH 5.5 and pH 9.0. A pH-induced conformational transition involves a peptide bond flip. J Mol Biol (1991) 2.19

Crystal structure of a thermostable type B DNA polymerase from Thermococcus gorgonarius. Proc Natl Acad Sci U S A (1999) 2.19

Refined crystal structure of ascorbate oxidase at 1.9 A resolution. J Mol Biol (1992) 2.18

Mechanism of inhibition of the human matrix metalloproteinase stromelysin-1 by TIMP-1. Nature (1997) 2.17

Structural homology of reaction centers from Rhodopseudomonas sphaeroides and Rhodopseudomonas viridis as determined by x-ray diffraction. Proc Natl Acad Sci U S A (1986) 2.16

Structural basis for the activation of human procaspase-7. Proc Natl Acad Sci U S A (2001) 2.14

Pyrobaculum aerophilum sp. nov., a novel nitrate-reducing hyperthermophilic archaeum. Appl Environ Microbiol (1993) 2.13

The mechanism of interference between an avian leukosis virus and Rous sarcoma virus. II. Early steps of infection by RSV of cells under conditions of interference. Virology (1966) 2.11

A fully automatic multimodality image registration algorithm. J Comput Assist Tomogr (1995) 2.11

Facilitation at the frog neuromuscular junction during and after repetitive stimulation. Pflugers Arch Gesamte Physiol Menschen Tiere (1966) 2.09

Structure of human des(1-45) factor Xa at 2.2 A resolution. J Mol Biol (1993) 2.07

Refined structure of the hirudin-thrombin complex. J Mol Biol (1991) 2.06

Refined three-dimensional structures of two cyanobacterial C-phycocyanins at 2.1 and 2.5 A resolution. A common principle of phycobilin-protein interaction. J Mol Biol (1987) 2.06

Potential changes recorded from the frog motor nerve terminal during its activation. Pflugers Arch Gesamte Physiol Menschen Tiere (1966) 2.06

Structural basis for the anticoagulant activity of the thrombin-thrombomodulin complex. Nature (2000) 2.04

Crystal structure of a DNA-dependent RNA polymerase (DNA primase). Nat Struct Biol (2001) 2.03

Structure of astacin and implications for activation of astacins and zinc-ligation of collagenases. Nature (1992) 2.02

Clostridium aceticum (Wieringa), a microorganism producing acetic acid from molecular hydrogen and carbon dioxide. Arch Microbiol (1981) 2.01

The refined 2.15 A X-ray crystal structure of human liver cathepsin B: the structural basis for its specificity. EMBO J (1991) 1.99

Structural and functional aspects of domain motions in proteins. CRC Crit Rev Biochem (1984) 1.99

The molecular structure of a dimer composed of the variable portions of the Bence-Jones protein REI refined at 2.0-A resolution. Biochemistry (1975) 1.98

Uridine transport and RNA synthesis in growing and in density-inhibited animal cells. J Cell Physiol (1971) 1.97

The transition of bovine trypsinogen to a trypsin-like state upon strong ligand binding. The refined crystal structures of the bovine trypsinogen-pancreatic trypsin inhibitor complex and of its ternary complex with Ile-Val at 1.9 A resolution. J Mol Biol (1978) 1.95

Targeting of a lysosomal membrane protein: a tyrosine-containing endocytosis signal in the cytoplasmic tail of lysosomal acid phosphatase is necessary and sufficient for targeting to lysosomes. EMBO J (1990) 1.93

Lesions of the posterior paraventricular thalamus block habituation of hypothalamic-pituitary-adrenal responses to repeated restraint. J Neuroendocrinol (2002) 1.91

Stimulation of glucose transport in cultures of density-inhibited chick embryo cells. Proc Natl Acad Sci U S A (1971) 1.91