Structure of 20S proteasome from yeast at 2.4 A resolution.

PubWeight™: 12.73‹?› | Rank: Top 0.1% | All-Time Top 10000

🔗 View Article (PMID 9087403)

Published in Nature on April 03, 1997

Authors

M Groll1, L Ditzel, J Löwe, D Stock, M Bochtler, H D Bartunik, R Huber

Author Affiliations

1: Max-Planck-Institut für Biochemie, Martinsreid, Germany.

Articles citing this

(truncated to the top 100)

Recognition and processing of ubiquitin-protein conjugates by the proteasome. Annu Rev Biochem (2009) 8.83

Precision and functional specificity in mRNA decay. Proc Natl Acad Sci U S A (2002) 8.20

The ubiquitin-proteasome pathway: on protein death and cell life. EMBO J (1998) 6.37

Negative Staining and Image Classification - Powerful Tools in Modern Electron Microscopy. Biol Proced Online (2004) 6.14

Epoxomicin, a potent and selective proteasome inhibitor, exhibits in vivo antiinflammatory activity. Proc Natl Acad Sci U S A (1999) 5.28

Proteasomal proteomics: identification of nucleotide-sensitive proteasome-interacting proteins by mass spectrometric analysis of affinity-purified proteasomes. Mol Biol Cell (2000) 5.19

The regulatory particle of the Saccharomyces cerevisiae proteasome. Mol Cell Biol (1998) 4.63

Docking of the proteasomal ATPases' carboxyl termini in the 20S proteasome's alpha ring opens the gate for substrate entry. Mol Cell (2007) 4.54

Large-scale protein structure modeling of the Saccharomyces cerevisiae genome. Proc Natl Acad Sci U S A (1998) 4.17

Ubiquitin-like protein involved in the proteasome pathway of Mycobacterium tuberculosis. Science (2008) 4.15

Sculpting the proteome with AAA(+) proteases and disassembly machines. Cell (2004) 3.83

Lessons from the genome sequence of Neurospora crassa: tracing the path from genomic blueprint to multicellular organism. Microbiol Mol Biol Rev (2004) 3.67

Mechanism of gate opening in the 20S proteasome by the proteasomal ATPases. Mol Cell (2008) 3.49

Regulation of Cdc28 cyclin-dependent protein kinase activity during the cell cycle of the yeast Saccharomyces cerevisiae. Microbiol Mol Biol Rev (1998) 3.44

Molecular architecture of the 26S proteasome holocomplex determined by an integrative approach. Proc Natl Acad Sci U S A (2012) 3.42

Dynamic association of proteasomal machinery with the centrosome. J Cell Biol (1999) 3.30

Antiviral activity of the proteasome on incoming human immunodeficiency virus type 1. J Virol (1998) 3.21

An essential protease involved in bacterial cell-cycle control. EMBO J (1998) 3.07

For whom the bell tolls: protein quality control of the endoplasmic reticulum and the ubiquitin-proteasome connection. EMBO J (2003) 2.82

Molecular mechanisms of proteasome assembly. Nat Rev Mol Cell Biol (2009) 2.82

Active site mutants in the six regulatory particle ATPases reveal multiple roles for ATP in the proteasome. EMBO J (1998) 2.82

Proteasome inhibitors in multiple myeloma: 10 years later. Blood (2012) 2.77

Structural insights into the regulatory particle of the proteasome from Methanocaldococcus jannaschii. Mol Cell (2009) 2.75

A protein-protein interaction map of the Caenorhabditis elegans 26S proteasome. EMBO Rep (2001) 2.74

Bortezomib as the first proteasome inhibitor anticancer drug: current status and future perspectives. Curr Cancer Drug Targets (2011) 2.58

Molecular mechanisms for the conversion of zymogens to active proteolytic enzymes. Protein Sci (1998) 2.52

The ubiquitin-proteasome pathway: the complexity and myriad functions of proteins death. Proc Natl Acad Sci U S A (1998) 2.40

Chlamydia inhibits interferon gamma-inducible major histocompatibility complex class II expression by degradation of upstream stimulatory factor 1. J Exp Med (1999) 2.39

Immunoproteasome assembly: cooperative incorporation of interferon gamma (IFN-gamma)-inducible subunits. J Exp Med (1998) 2.32

Relative structural and functional roles of multiple deubiquitylating proteins associated with mammalian 26S proteasome. Mol Biol Cell (2007) 2.28

ATP binds to proteasomal ATPases in pairs with distinct functional effects, implying an ordered reaction cycle. Cell (2011) 2.27

Discrete cleavage motifs of constitutive and immunoproteasomes revealed by quantitative analysis of cleavage products. J Exp Med (2001) 2.27

ATP binding and ATP hydrolysis play distinct roles in the function of 26S proteasome. Mol Cell (2006) 2.26

Transcription factor Nrf1 mediates the proteasome recovery pathway after proteasome inhibition in mammalian cells. Mol Cell (2010) 2.24

A degradation signal located in the C-terminus of p21WAF1/CIP1 is a binding site for the C8 alpha-subunit of the 20S proteasome. EMBO J (2001) 2.22

Targeting proteins for degradation. Nat Chem Biol (2009) 2.22

Dynamics of proteasome distribution in living cells. EMBO J (1997) 2.18

A role for N-glycanase in the cytosolic turnover of glycoproteins. EMBO J (2003) 2.18

The ubiquitin-proteasome pathway and proteasome inhibitors. Med Res Rev (2001) 2.18

A phase 1 dose escalation study of the safety and pharmacokinetics of the novel proteasome inhibitor carfilzomib (PR-171) in patients with hematologic malignancies. Clin Cancer Res (2009) 2.17

Proteasome inhibitors block development of Plasmodium spp. Antimicrob Agents Chemother (1998) 2.07

Chaperone-mediated pathway of proteasome regulatory particle assembly. Nature (2009) 2.07

Subcellular distribution of proteasomes implicates a major location of protein degradation in the nuclear envelope-ER network in yeast. EMBO J (1998) 2.06

Structure of the 26S proteasome from Schizosaccharomyces pombe at subnanometer resolution. Proc Natl Acad Sci U S A (2010) 2.05

Near-atomic resolution structural model of the yeast 26S proteasome. Proc Natl Acad Sci U S A (2012) 2.04

Molecular architecture and assembly of the eukaryotic proteasome. Annu Rev Biochem (2013) 2.04

Identification of the yeast 20S proteasome catalytic centers and subunit interactions required for active-site formation. Proc Natl Acad Sci U S A (1997) 1.99

Structural insights on the Mycobacterium tuberculosis proteasomal ATPase Mpa. Structure (2009) 1.96

Identification of substrates of the Mycobacterium tuberculosis proteasome. EMBO J (2006) 1.96

Differential roles of the COOH termini of AAA subunits of PA700 (19 S regulator) in asymmetric assembly and activation of the 26 S proteasome. J Biol Chem (2008) 1.93

Distinct static and dynamic interactions control ATPase-peptidase communication in a AAA+ protease. Mol Cell (2007) 1.91

A proteasome for all occasions. FEBS Lett (2007) 1.84

Chaperonin function: folding by forced unfolding. Science (1999) 1.83

SKP1-SnRK protein kinase interactions mediate proteasomal binding of a plant SCF ubiquitin ligase. EMBO J (2001) 1.83

The proteasome: overview of structure and functions. Proc Jpn Acad Ser B Phys Biol Sci (2009) 1.82

The central unit within the 19S regulatory particle of the proteasome. Nat Struct Mol Biol (2008) 1.82

Insights into the molecular architecture of the 26S proteasome. Proc Natl Acad Sci U S A (2009) 1.81

Pleiotropic defects caused by loss of the proteasome-interacting factors Rad23 and Rpn10 of Saccharomyces cerevisiae. Genetics (1999) 1.81

Mutational studies on HslU and its docking mode with HslV. Proc Natl Acad Sci U S A (2000) 1.79

Expanding the chemical cross-linking toolbox by the use of multiple proteases and enrichment by size exclusion chromatography. Mol Cell Proteomics (2012) 1.77

Discovery and development of the anticancer agent salinosporamide A (NPI-0052). Bioorg Med Chem (2008) 1.77

Crystal structure of heat shock locus V (HslV) from Escherichia coli. Proc Natl Acad Sci U S A (1997) 1.75

The ubiquitin-proteasome system of Saccharomyces cerevisiae. Genetics (2012) 1.73

Cleavage motifs of the yeast 20S proteasome beta subunits deduced from digests of enolase 1. Proc Natl Acad Sci U S A (1998) 1.72

Protein binding and unfolding by the chaperone ClpA and degradation by the protease ClpAP. Proc Natl Acad Sci U S A (2000) 1.72

IFN-gamma-induced immune adaptation of the proteasome system is an accelerated and transient response. Proc Natl Acad Sci U S A (2005) 1.70

Two abundant proteasome subtypes that uniquely process some antigens presented by HLA class I molecules. Proc Natl Acad Sci U S A (2010) 1.70

Quantitative NMR spectroscopy of supramolecular complexes: dynamic side pores in ClpP are important for product release. Proc Natl Acad Sci U S A (2005) 1.68

Proteasomes in immune cells: more than peptide producers? Nat Rev Immunol (2009) 1.67

Intermediates in the formation of mouse 20S proteasomes: implications for the assembly of precursor beta subunits. EMBO J (1997) 1.67

Toward detecting and identifying macromolecules in a cellular context: template matching applied to electron tomograms. Proc Natl Acad Sci U S A (2000) 1.67

Chaperone rings in protein folding and degradation. Proc Natl Acad Sci U S A (1999) 1.66

The role of the ClpA chaperone in proteolysis by ClpAP. Proc Natl Acad Sci U S A (1998) 1.65

Crystal structure of an intracellular protease from Pyrococcus horikoshii at 2-A resolution. Proc Natl Acad Sci U S A (2000) 1.65

Role of proteasomes in disease. BMC Biochem (2007) 1.65

The subunits MECL-1 and LMP2 are mutually required for incorporation into the 20S proteasome. Proc Natl Acad Sci U S A (1997) 1.64

Structure of the Rpn11-Rpn8 dimer reveals mechanisms of substrate deubiquitination during proteasomal degradation. Nat Struct Mol Biol (2014) 1.63

Proteasome activators. Mol Cell (2011) 1.62

The catalytic sites of 20S proteasomes and their role in subunit maturation: a mutational and crystallographic study. Proc Natl Acad Sci U S A (1999) 1.62

The proteasome activator 11 S REG (PA28) and class I antigen presentation. Biochem J (2000) 1.62

Localization of the 26S proteasome during mitosis and meiosis in fission yeast. EMBO J (1998) 1.61

Mechanism of substrate unfolding and translocation by the regulatory particle of the proteasome from Methanocaldococcus jannaschii. Mol Cell (2009) 1.61

Assembly, structure, and function of the 26S proteasome. Trends Cell Biol (2010) 1.61

Interactions of PAN's C-termini with archaeal 20S proteasome and implications for the eukaryotic proteasome-ATPase interactions. EMBO J (2009) 1.60

Structures of ClpP in complex with acyldepsipeptide antibiotics reveal its activation mechanism. Nat Struct Mol Biol (2010) 1.60

Targeting the insulin-like growth factor-1 receptor to overcome bortezomib resistance in preclinical models of multiple myeloma. Blood (2012) 1.58

The proteasomal subunit Rpn6 is a molecular clamp holding the core and regulatory subcomplexes together. Proc Natl Acad Sci U S A (2011) 1.57

Regulated protein turnover: snapshots of the proteasome in action. Nat Rev Mol Cell Biol (2014) 1.57

Peptide-guided gene delivery. AAPS J (2007) 1.57

The ubiquitin-proteasome pathway in cancer. Br J Cancer (1998) 1.56

The 26 S proteasome: from basic mechanisms to drug targeting. J Biol Chem (2009) 1.55

Structural comparison of Ntn-hydrolases. Protein Sci (2000) 1.55

Identification of an activation region in the proteasome activator REGalpha. Proc Natl Acad Sci U S A (1998) 1.54

A map of human protein interactions derived from co-expression of human mRNAs and their orthologs. Mol Syst Biol (2008) 1.53

A glycosylated type I membrane protein becomes cytosolic when peptide: N-glycanase is compromised. EMBO J (2004) 1.53

Regulation of proteasome activity in health and disease. Biochim Biophys Acta (2013) 1.52

beta-Subunit appendages promote 20S proteasome assembly by overcoming an Ump1-dependent checkpoint. EMBO J (2007) 1.52

The ubiquitin-proteasome system: opportunities for therapeutic intervention in solid tumors. Endocr Relat Cancer (2014) 1.52

An inhibitor of HIV-1 protease modulates proteasome activity, antigen presentation, and T cell responses. Proc Natl Acad Sci U S A (1998) 1.50

Structure of the 26S proteasome with ATP-γS bound provides insights into the mechanism of nucleotide-dependent substrate translocation. Proc Natl Acad Sci U S A (2013) 1.50

Articles by these authors

Crystal structure of the 20S proteasome from the archaeon T. acidophilum at 3.4 A resolution. Science (1995) 12.94

X-ray structure analysis of a membrane protein complex. Electron density map at 3 A resolution and a model of the chromophores of the photosynthetic reaction center from Rhodopseudomonas viridis. J Mol Biol (1984) 8.85

The complete genome of the hyperthermophilic bacterium Aquifex aeolicus. Nature (1998) 7.77

Prokaryotic origin of the actin cytoskeleton. Nature (2001) 6.44

A gated channel into the proteasome core particle. Nat Struct Biol (2000) 5.42

Structure of the protein subunits in the photosynthetic reaction centre of Rhodopseudomonas viridis at 3Å resolution. Nature (2012) 5.22

Mutations in GPC3, a glypican gene, cause the Simpson-Golabi-Behmel overgrowth syndrome. Nat Genet (1996) 4.62

The refined 1.9 A crystal structure of human alpha-thrombin: interaction with D-Phe-Pro-Arg chloromethylketone and significance of the Tyr-Pro-Pro-Trp insertion segment. EMBO J (1989) 4.49

Fourier Domain Mode Locking (FDML): A new laser operating regime and applications for optical coherence tomography. Opt Express (2006) 4.49

The structures of HsIU and the ATP-dependent protease HsIU-HsIV. Nature (2000) 4.46

Structure of bovine pancreatic trypsin inhibitor. Results of joint neutron and X-ray refinement of crystal form II. J Mol Biol (1984) 4.14

Proteasome from Thermoplasma acidophilum: a threonine protease. Science (1995) 3.62

Human alpha 1-proteinase inhibitor. Crystal structure analysis of two crystal modifications, molecular model and preliminary analysis of the implications for function. J Mol Biol (1984) 3.60

The 3.2-A crystal structure of the human IgG1 Fc fragment-Fc gammaRIII complex. Nature (2000) 3.53

Tubulin and FtsZ form a distinct family of GTPases. Nat Struct Biol (1998) 3.29

Crystallographic refinement and atomic models of two different forms of citrate synthase at 2.7 and 1.7 A resolution. J Mol Biol (1982) 3.28

Natural protein proteinase inhibitors and their interaction with proteinases. Eur J Biochem (1992) 3.27

Structural analysis of human IgG-Fc glycoforms reveals a correlation between glycosylation and structural integrity. J Mol Biol (2003) 3.25

Crystallographic refinement and atomic models of the intact immunoglobulin molecule Kol and its antigen-binding fragment at 3.0 A and 1.0 A resolution. J Mol Biol (1980) 3.25

Structure of the complex formed by bovine trypsin and bovine pancreatic trypsin inhibitor. II. Crystallographic refinement at 1.9 A resolution. J Mol Biol (1974) 3.17

The proteasome. Annu Rev Biophys Biomol Struct (1999) 3.13

Crystallographic structure studies of an IgG molecule and an Fc fragment. Nature (1976) 3.00

Crystal structure of the thermosome, the archaeal chaperonin and homolog of CCT. Cell (1998) 2.94

Structure of the tetrameric restriction endonuclease NgoMIV in complex with cleaved DNA. Nat Struct Biol (2000) 2.82

Crystal structure of a carbon monoxide dehydrogenase reveals a [Ni-4Fe-5S] cluster. Science (2001) 2.78

The structure of a complex of recombinant hirudin and human alpha-thrombin. Science (1990) 2.71

Structure and mechanism of the aberrant ba(3)-cytochrome c oxidase from thermus thermophilus. EMBO J (2000) 2.71

Structure determination and refinement of human alpha class glutathione transferase A1-1, and a comparison with the Mu and Pi class enzymes. J Mol Biol (1993) 2.66

Phosphotransferase and substrate binding mechanism of the cAMP-dependent protein kinase catalytic subunit from porcine heart as deduced from the 2.0 A structure of the complex with Mn2+ adenylyl imidodiphosphate and inhibitor peptide PKI(5-24). EMBO J (1993) 2.54

Human C1 inhibitor: primary structure, cDNA cloning, and chromosomal localization. Biochemistry (1986) 2.52

Amplified, frequency swept lasers for frequency domain reflectometry and OCT imaging: design and scaling principles. Opt Express (2005) 2.48

The 2.0 A X-ray crystal structure of chicken egg white cystatin and its possible mode of interaction with cysteine proteinases. EMBO J (1988) 2.48

The refined 2.4 A X-ray crystal structure of recombinant human stefin B in complex with the cysteine proteinase papain: a novel type of proteinase inhibitor interaction. EMBO J (1990) 2.44

High-level biosynthetic substitution of methionine in proteins by its analogs 2-aminohexanoic acid, selenomethionine, telluromethionine and ethionine in Escherichia coli. Eur J Biochem (1995) 2.44

X-ray crystallographic structure of the light-harvesting biliprotein C-phycocyanin from the thermophilic cyanobacterium Mastigocladus laminosus and its resemblance to globin structures. J Mol Biol (1985) 2.42

Crystal structure of P22 tailspike protein: interdigitated subunits in a thermostable trimer. Science (1994) 2.41

The blue oxidases, ascorbate oxidase, laccase and ceruloplasmin. Modelling and structural relationships. Eur J Biochem (1990) 2.37

X-ray crystal structures of cytosolic glutathione S-transferases. Implications for protein architecture, substrate recognition and catalytic function. Eur J Biochem (1994) 2.37

A steric mechanism for inhibition of CO binding to heme proteins. Science (1999) 2.36

The three-dimensional structure of class pi glutathione S-transferase in complex with glutathione sulfonate at 2.3 A resolution. EMBO J (1991) 2.36

Organic anion-transporting polypeptide B (OATP-B) and its functional comparison with three other OATPs of human liver. Gastroenterology (2001) 2.36

Crystal structure analysis of oxidized Pseudomonas aeruginosa azurin at pH 5.5 and pH 9.0. A pH-induced conformational transition involves a peptide bond flip. J Mol Biol (1991) 2.19

Crystal structure of a thermostable type B DNA polymerase from Thermococcus gorgonarius. Proc Natl Acad Sci U S A (1999) 2.19

Refined crystal structure of ascorbate oxidase at 1.9 A resolution. J Mol Biol (1992) 2.18

Mechanism of inhibition of the human matrix metalloproteinase stromelysin-1 by TIMP-1. Nature (1997) 2.17

Structural homology of reaction centers from Rhodopseudomonas sphaeroides and Rhodopseudomonas viridis as determined by x-ray diffraction. Proc Natl Acad Sci U S A (1986) 2.16

Structural basis for the activation of human procaspase-7. Proc Natl Acad Sci U S A (2001) 2.14

Pyrobaculum aerophilum sp. nov., a novel nitrate-reducing hyperthermophilic archaeum. Appl Environ Microbiol (1993) 2.13

Structure of human des(1-45) factor Xa at 2.2 A resolution. J Mol Biol (1993) 2.07

Refined structure of the hirudin-thrombin complex. J Mol Biol (1991) 2.06

Refined three-dimensional structures of two cyanobacterial C-phycocyanins at 2.1 and 2.5 A resolution. A common principle of phycobilin-protein interaction. J Mol Biol (1987) 2.06

Crystal structure of the N-terminal domain of MukB: a protein involved in chromosome partitioning. Structure (1999) 2.04

Structural basis for the anticoagulant activity of the thrombin-thrombomodulin complex. Nature (2000) 2.04

Crystal structure of a DNA-dependent RNA polymerase (DNA primase). Nat Struct Biol (2001) 2.03

Structure of astacin and implications for activation of astacins and zinc-ligation of collagenases. Nature (1992) 2.02

The refined 2.15 A X-ray crystal structure of human liver cathepsin B: the structural basis for its specificity. EMBO J (1991) 1.99

Structural and functional aspects of domain motions in proteins. CRC Crit Rev Biochem (1984) 1.99

The molecular structure of a dimer composed of the variable portions of the Bence-Jones protein REI refined at 2.0-A resolution. Biochemistry (1975) 1.98

Crystal structure of the cell division protein FtsA from Thermotoga maritima. EMBO J (2000) 1.97

The transition of bovine trypsinogen to a trypsin-like state upon strong ligand binding. The refined crystal structures of the bovine trypsinogen-pancreatic trypsin inhibitor complex and of its ternary complex with Ile-Val at 1.9 A resolution. J Mol Biol (1978) 1.95

Lesions of the posterior paraventricular thalamus block habituation of hypothalamic-pituitary-adrenal responses to repeated restraint. J Neuroendocrinol (2002) 1.91

X-ray crystal structure of the blue oxidase ascorbate oxidase from zucchini. Analysis of the polypeptide fold and a model of the copper sites and ligands. J Mol Biol (1989) 1.90

Three-dimensional structure of the complex between pancreatic secretory trypsin inhibitor (Kazal type) and trypsinogen at 1.8 A resolution. Structure solution, crystallographic refinement and preliminary structural interpretation. J Mol Biol (1982) 1.90

The ternary microplasmin-staphylokinase-microplasmin complex is a proteinase-cofactor-substrate complex in action. Nat Struct Biol (1998) 1.85

Mistletoe therapy in oncology. Cochrane Database Syst Rev (2008) 1.84

Bovine chymotrypsinogen A X-ray crystal structure analysis and refinement of a new crystal form at 1.8 A resolution. J Mol Biol (1985) 1.81

How Taxol stabilises microtubule structure. Chem Biol (1999) 1.79

Crystal structure of gingipain R: an Arg-specific bacterial cysteine proteinase with a caspase-like fold. EMBO J (1999) 1.79

Crystal structure of bovine trypsinogen at 1-8 A resolution. II. Crystallographic refinement, refined crystal structure and comparison with bovine trypsin. J Mol Biol (1977) 1.79

Mutational studies on HslU and its docking mode with HslV. Proc Natl Acad Sci U S A (2000) 1.79

Crystal structure of the complex formed by the membrane type 1-matrix metalloproteinase with the tissue inhibitor of metalloproteinases-2, the soluble progelatinase A receptor. EMBO J (1998) 1.79

Comparison of two highly refined structures of bovine pancreatic trypsin inhibitor. J Mol Biol (1987) 1.77

Crystal and molecular structure of a dimer composed of the variable portions of the Bence-Jones protein REI. Eur J Biochem (1974) 1.76

X-ray crystal structure of the complex of human leukocyte elastase (PMN elastase) and the third domain of the turkey ovomucoid inhibitor. EMBO J (1986) 1.76

Crystal structure of heat shock locus V (HslV) from Escherichia coli. Proc Natl Acad Sci U S A (1997) 1.75

Ultrahigh-speed optical coherence tomography imaging and visualization of the embryonic avian heart using a buffered Fourier Domain Mode Locked laser. Opt Express (2007) 1.75

Crystal structure of the xanthine oxidase-related aldehyde oxido-reductase from D. gigas. Science (1995) 1.74

Three-dimensional structure of class pi glutathione S-transferase from human placenta in complex with S-hexylglutathione at 2.8 A resolution. J Mol Biol (1992) 1.73

Structure of the complex formed by bovine trypsin and bovine pancreatic trypsin inhibitor. Crystal structure determination and stereochemistry of the contact region. J Mol Biol (1973) 1.73

Cleavage motifs of the yeast 20S proteasome beta subunits deduced from digests of enolase 1. Proc Natl Acad Sci U S A (1998) 1.72

The crystal structure of dihydrodipicolinate synthase from Escherichia coli at 2.5 A resolution. J Mol Biol (1995) 1.70

Crystal structure of the catalytic domain of human tumor necrosis factor-alpha-converting enzyme. Proc Natl Acad Sci U S A (1998) 1.70

The X-ray crystal structure of the catalytic domain of human neutrophil collagenase inhibited by a substrate analogue reveals the essentials for catalysis and specificity. EMBO J (1994) 1.68

Coherent structural dynamics and electronic correlations during an ultrafast insulator-to-metal phase transition in VO2. Phys Rev Lett (2007) 1.67

Tachylectin-2: crystal structure of a specific GlcNAc/GalNAc-binding lectin involved in the innate immunity host defense of the Japanese horseshoe crab Tachypleus tridentatus. EMBO J (1999) 1.67

Crystal structure of phage P22 tailspike protein complexed with Salmonella sp. O-antigen receptors. Proc Natl Acad Sci U S A (1996) 1.66

The crystal structure of calcium-free human m-calpain suggests an electrostatic switch mechanism for activation by calcium. Proc Natl Acad Sci U S A (2000) 1.65

The catalytic sites of 20S proteasomes and their role in subunit maturation: a mutational and crystallographic study. Proc Natl Acad Sci U S A (1999) 1.62

Reaction mechanism of Escherichia coli dihydrodipicolinate synthase investigated by X-ray crystallography and NMR spectroscopy. Biochemistry (1997) 1.62