Aspiration pneumonitis and aspiration pneumonia.

PubWeight™: 6.51‹?› | Rank: Top 1%

🔗 View Article (PMID 11228282)

Published in N Engl J Med on March 01, 2001

Authors

P E Marik1

Author Affiliations

1: Section of Critical Care Medicine, Mercy Hospital of Pittsburgh, PA 15219-5166, USA. pmarik@zbzoom.net

Associated clinical trials:

Aspiration in Acute Respiratory Failure Survivors | NCT02363686

Improving Oral Care to Reduce Hospital-Acquired Pneumonia (HAP) in the Acute Neurologically Impaired Adult | NCT01498601

Articles citing this

(truncated to the top 100)

Stroke-induced immunodeficiency promotes spontaneous bacterial infections and is mediated by sympathetic activation reversal by poststroke T helper cell type 1-like immunostimulation. J Exp Med (2003) 3.89

Complete reversal of acid-induced acute lung injury by blocking of platelet-neutrophil aggregation. J Clin Invest (2006) 3.38

Early identification of patients at risk of acute lung injury: evaluation of lung injury prediction score in a multicenter cohort study. Am J Respir Crit Care Med (2010) 3.21

Post-stroke infection: a systematic review and meta-analysis. BMC Neurol (2011) 2.29

Anatomy and physiology of feeding and swallowing: normal and abnormal. Phys Med Rehabil Clin N Am (2008) 2.07

Association of prehospitalization aspirin therapy and acute lung injury: results of a multicenter international observational study of at-risk patients. Crit Care Med (2011) 2.03

Early management after self-poisoning with an organophosphorus or carbamate pesticide - a treatment protocol for junior doctors. Crit Care (2004) 1.94

The anti-inflammatory and proresolving mediator resolvin E1 protects mice from bacterial pneumonia and acute lung injury. J Immunol (2009) 1.71

Tropheryma whipplei in patients with pneumonia. Emerg Infect Dis (2010) 1.59

Tracheobronchial aspiration of gastric contents in critically ill tube-fed patients: frequency, outcomes, and risk factors. Crit Care Med (2006) 1.57

Nausea, vomiting, and hiccups: a review of mechanisms and treatment. Anesth Prog (2010) 1.50

Aspirin-triggered resolvin D1 reduces mucosal inflammation and promotes resolution in a murine model of acute lung injury. Mucosal Immunol (2012) 1.49

Predictors of pneumonia in acute stroke patients admitted to a neurological intensive care unit. J Neurol (2007) 1.40

Aspiration-induced lung injury. Crit Care Med (2011) 1.40

Lung contusion: inflammatory mechanisms and interaction with other injuries. Shock (2009) 1.32

Prehospitalization antiplatelet therapy is associated with a reduced incidence of acute lung injury: a population-based cohort study. Chest (2010) 1.30

Therapeutic inhibition of CXCR2 by Reparixin attenuates acute lung injury in mice. Br J Pharmacol (2008) 1.30

Does chronic microaspiration cause idiopathic pulmonary fibrosis? Am J Med (2010) 1.30

Reflux related hospital admissions after fundoplication in children with neurological impairment: retrospective cohort study. BMJ (2009) 1.20

Risk factors and prognosis of pulmonary complications after endoscopic submucosal dissection for gastric neoplasia. Dig Dis Sci (2012) 1.16

Postextubation dysphagia is persistent and associated with poor outcomes in survivors of critical illness. Crit Care (2011) 1.15

Senescent swallowing: impact, strategies, and interventions. Nutr Clin Pract (2009) 1.12

Nursing home-associated pneumonia, hospital-acquired pneumonia and ventilator-associated pneumonia: the contribution of dental biofilms and periodontal inflammation. Periodontol 2000 (2007) 1.12

Are we ready for novel detection methods to treat respiratory pathogens in hospital-acquired pneumonia? Clin Infect Dis (2011) 1.11

The role of platelets in acute lung injury (ALI). Front Biosci (Landmark Ed) (2009) 1.10

Repertoire of intensive care unit pneumonia microbiota. PLoS One (2012) 1.10

Pneumonia in acute stroke patients fed by nasogastric tube. J Neurol Neurosurg Psychiatry (2004) 1.08

Surfactant dysfunction in lung contusion with and without superimposed gastric aspiration in a rat model. Shock (2008) 1.07

Current treatments in familial dysautonomia. Expert Opin Pharmacother (2014) 1.06

The accuracy of natriuretic peptides (brain natriuretic peptide and N-terminal pro-brain natriuretic) in the differentiation between transfusion-related acute lung injury and transfusion-related circulatory overload in the critically ill. Transfusion (2008) 1.04

The upper respiratory tract as a microbial source for pulmonary infections in cystic fibrosis. Parallels from island biogeography. Am J Respir Crit Care Med (2014) 1.00

Dysphagia as a risk factor for mortality in Niemann-Pick disease type C: systematic literature review and evidence from studies with miglustat. Orphanet J Rare Dis (2012) 0.99

Maresin 1 biosynthesis during platelet-neutrophil interactions is organ-protective. Proc Natl Acad Sci U S A (2014) 0.99

The role of the local microbial ecosystem in respiratory health and disease. Philos Trans R Soc Lond B Biol Sci (2015) 0.99

Superimposed gastric aspiration increases the severity of inflammation and permeability injury in a rat model of lung contusion. J Surg Res (2008) 0.98

Aspiration pneumonia after chemo-intensity-modulated radiation therapy of oropharyngeal carcinoma and its clinical and dysphagia-related predictors. Head Neck (2013) 0.98

Predicting risk of postoperative lung injury in high-risk surgical patients: a multicenter cohort study. Anesthesiology (2014) 0.97

Mortality, morbidity, and disease severity of patients with aspiration pneumonia. J Hosp Med (2012) 0.96

Inhibition of acid-induced lung injury by hyperosmolar sucrose in rats. Am J Respir Crit Care Med (2005) 0.95

Resolution of Toll-like receptor 4-mediated acute lung injury is linked to eicosanoids and suppressor of cytokine signaling 3. FASEB J (2011) 0.95

Accuracy of alpha amylase in diagnosing microaspiration in intubated critically-ill patients. PLoS One (2014) 0.95

VEGF regulates the proliferation of acid-exposed alveolar lining epithelial cells. Thorax (2003) 0.93

Post-extubation dysphagia is associated with longer hospitalization in survivors of critical illness with neurologic impairment. Crit Care (2013) 0.93

Aspiration pneumonia after concurrent chemoradiotherapy for head and neck cancer. Cancer (2014) 0.92

Pulmonary vs nonpulmonary sepsis and mortality in acute lung injury. Chest (2008) 0.92

Detection of plant DNA in the bronchoalveolar lavage of patients with ventilator-associated pneumonia. PLoS One (2010) 0.91

Alcohol consumption and development of acute respiratory distress syndrome: a population-based study. Int J Environ Res Public Health (2009) 0.91

Towards the prevention of acute lung injury: a population based cohort study protocol. BMC Emerg Med (2010) 0.91

Management of community-acquired pneumonia in older adults. Ther Adv Infect Dis (2014) 0.89

Presence of neutrophil extracellular traps and citrullinated histone H3 in the bloodstream of critically ill patients. PLoS One (2014) 0.86

The effects of increased fluid viscosity on swallowing sounds in healthy adults. Biomed Eng Online (2013) 0.86

Recognition and management of complications during moderate and deep sedation part 1: respiratory considerations. Anesth Prog (2011) 0.86

Characteristics associated with clinician diagnosis of aspiration pneumonia: a descriptive study of afflicted patients and their outcomes. J Hosp Med (2014) 0.86

Biomarkers in the diagnosis of aspiration syndromes. Expert Rev Mol Diagn (2010) 0.86

Observed association between antidepressant use and pneumonia risk was confounded by comorbidity measures. J Clin Epidemiol (2007) 0.85

Effects of pulmonary acid aspiration on the lungs and extra-pulmonary organs: a randomized study in pigs. Crit Care (2012) 0.85

Efficacy of half-solid nutrient for the elderly patients with percutaneous endoscopic gastrostomy. J Clin Biochem Nutr (2011) 0.85

Can we use influencing factors to predict aspiration pneumonia in the United Kingdom? Multidiscip Respir Med (2013) 0.84

Towards prevention of acute lung injury: frequency and outcomes of emergency department patients at-risk - a multicenter cohort study. Int J Emerg Med (2012) 0.84

Optimizing the management of elderly colorectal surgery patients. Surg Today (2010) 0.84

Characteristics and outcomes of patients hospitalized following pulmonary aspiration. Chest (2014) 0.84

[Pneumonia Severity Index (PSI), CURB-65, and mortality in hospitalized elderly patients with aspiration pneumonia]. Z Gerontol Geriatr (2011) 0.84

Imaging of community-acquired pneumonia: Roles of imaging examinations, imaging diagnosis of specific pathogens and discrimination from noninfectious diseases. World J Radiol (2014) 0.84

Deep sedation during catheter ablation for atrial fibrillation in elderly patients. J Interv Card Electrophysiol (2013) 0.84

Respiratory complications of organophosphorus nerve agent and insecticide poisoning. Implications for respiratory and critical care. Am J Respir Crit Care Med (2014) 0.83

Time-dependent rheology of starch thickeners and the clinical implications for dysphagia therapy. Dysphagia (2006) 0.83

Healthcare-associated Pneumonia and Aspiration Pneumonia. Aging Dis (2014) 0.83

Pharyngeal swallowing phase and chronic cough. Int Arch Otorhinolaryngol (2012) 0.82

The burden and etiology of community-onset pneumonia in the aging Japanese population: a multicenter prospective study. PLoS One (2015) 0.82

A statistical analysis of cervical auscultation signals from adults with unsafe airway protection. J Neuroeng Rehabil (2016) 0.81

Comparison of clinical characteristics and outcomes between aspiration pneumonia and community-acquired pneumonia in patients with chronic obstructive pulmonary disease. BMC Pulm Med (2015) 0.81

Predictive modeling and inflammatory biomarkers in rats with lung contusion and gastric aspiration. J Trauma (2009) 0.81

Special issues in the management and selection of the donor for lung transplantation. Semin Immunopathol (2011) 0.81

A new category--healthcare-associated pneumonia: a good idea, but problems with its execution. Eur J Clin Microbiol Infect Dis (2006) 0.81

Dysphagia, dystussia, and aspiration pneumonia in elderly people. J Thorac Dis (2016) 0.81

Anatomic and physiopathologic changes affecting the airway of the elderly patient: implications for geriatric-focused airway management. Clin Interv Aging (2015) 0.80

Acute respiratory distress syndrome and lung injury: Pathogenetic mechanism and therapeutic implication. World J Crit Care Med (2012) 0.80

Correlation between brain injury and dysphagia in adult patients with stroke. Int Arch Otorhinolaryngol (2012) 0.79

Characterisation of Candida within the Mycobiome/Microbiome of the Lower Respiratory Tract of ICU Patients. PLoS One (2016) 0.79

Effect of high advanced glycation end-product diet on pulmonary inflammatory response and pulmonary function following gastric aspiration. Shock (2012) 0.79

Altered mucosal immune response after acute lung injury in a murine model of Ataxia Telangiectasia. BMC Pulm Med (2014) 0.79

Acid contact in the rodent pulmonary alveolus causes proinflammatory signaling by membrane pore formation. Am J Physiol Lung Cell Mol Physiol (2012) 0.79

Associations of Adverse Clinical Course and Ingested Substances among Patients with Deliberate Drug Poisoning: A Cohort Study from an Intensive Care Unit in Japan. PLoS One (2016) 0.79

Translocation and dissemination of commensal bacteria in post-stroke infection. Nat Med (2016) 0.79

Serologic prevalence of amoeba-associated microorganisms in intensive care unit pneumonia patients. PLoS One (2013) 0.78

Reduced pulmonary blood flow in regions of injury 2 hours after acid aspiration in rats. BMC Anesthesiol (2015) 0.78

Aspiration-related deaths in 57 consecutive patients: autopsy study. PLoS One (2014) 0.78

Functional contribution of CXCR2 to lung injury after aspiration of acid and gastric particulates. Am J Physiol Lung Cell Mol Physiol (2009) 0.78

Ethical challenges of percutaneous endoscopic gastrostomy. Surg Endosc (2004) 0.78

Does a Water Protocol Improve the Hydration and Health Status of Individuals with Thin Liquid Aspiration Following Stroke? A Randomized Controlled Trial. Dysphagia (2016) 0.77

Incidence of Pneumonia After Videofluoroscopic Swallowing Study and Associated Factors. Dysphagia (2015) 0.77

Retracted Recurrent/Persistent Pneumonia among Children in Upper Egypt. Mediterr J Hematol Infect Dis (2013) 0.77

Mosapride accelerates the delayed gastric emptying of high-viscosity liquids: a crossover study using continuous real-time C breath test (BreathID System). J Neurogastroenterol Motil (2011) 0.77

Resolvin D3 and Aspirin-Triggered Resolvin D3 Are Protective for Injured Epithelia. Am J Pathol (2016) 0.77

Glutamine attenuates acute lung injury caused by acid aspiration. Nutrients (2014) 0.77

Synergy between acid and endotoxin in an experimental model of aspiration-related lung injury progression. Am J Physiol Lung Cell Mol Physiol (2015) 0.77

PTEN-Foxo1 signaling triggers HMGB1-mediated innate immune responses in acute lung injury. Immunol Res (2015) 0.77

Pneumonia after endoscopic resection for gastric neoplasm. Dig Dis Sci (2014) 0.76

Association of severe hypertension with pneumonia in elderly patients with acute ischemic stroke. Hypertens Res (2012) 0.76

A new experimental model of acid- and endotoxin-induced acute lung injury in rats. Am J Physiol Lung Cell Mol Physiol (2016) 0.76