Published in Biochemistry on May 06, 1975
The Clothes Make the mRNA: Past and Present Trends in mRNP Fashion. Annu Rev Biochem (2015) 1.04
Characterization of mRNA-protein complexes from mammalian cells. Nucleic Acids Res (1977) 1.04
Cytoplasmic polyadenylate processing events accompany the transfer of mRNA from the free mRNP particles to the polysomes in Physarum. Proc Natl Acad Sci U S A (1981) 0.94
The coregulator exchange in transcriptional functions of nuclear receptors. Genes Dev (2000) 11.65
A CBP integrator complex mediates transcriptional activation and AP-1 inhibition by nuclear receptors. Cell (1996) 11.02
A complex containing N-CoR, mSin3 and histone deacetylase mediates transcriptional repression. Nature (1997) 9.71
The transcriptional co-activator p/CIP binds CBP and mediates nuclear-receptor function. Nature (1997) 8.38
Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-gamma. Nature (1998) 8.33
Primary structure and expression of a functional human glucocorticoid receptor cDNA. Nature (1986) 7.81
Alternative RNA processing in calcitonin gene expression generates mRNAs encoding different polypeptide products. Nature (1982) 6.56
The POU domain: a large conserved region in the mammalian pit-1, oct-1, oct-2, and Caenorhabditis elegans unc-86 gene products. Genes Dev (1988) 6.23
RXR beta: a coregulator that enhances binding of retinoic acid, thyroid hormone, and vitamin D receptors to their cognate response elements. Cell (1991) 5.89
Expression of a large family of POU-domain regulatory genes in mammalian brain development. Nature (1989) 5.68
Production of a novel neuropeptide encoded by the calcitonin gene via tissue-specific RNA processing. Nature (1983) 5.20
Dwarf locus mutants lacking three pituitary cell types result from mutations in the POU-domain gene pit-1. Nature (1990) 5.20
Coactivator and corepressor complexes in nuclear receptor function. Curr Opin Genet Dev (1999) 4.92
Complex transcriptional units: diversity in gene expression by alternative RNA processing. Annu Rev Biochem (1986) 4.73
Functional domains of the human glucocorticoid receptor. Cell (1986) 4.68
A tissue-specific transcription factor containing a homeodomain specifies a pituitary phenotype. Cell (1988) 4.57
Transcription factor-specific requirements for coactivators and their acetyltransferase functions. Science (1998) 4.55
Dramatic growth of mice that develop from eggs microinjected with metallothionein-growth hormone fusion genes. Nature (1982) 4.30
The orientation and spacing of core DNA-binding motifs dictate selective transcriptional responses to three nuclear receptors. Cell (1991) 4.27
Regulation of neuronal traits by a novel transcriptional complex. Neuron (2001) 4.02
The thyroid hormone receptor binds with opposite transcriptional effects to a common sequence motif in thyroid hormone and estrogen response elements. Cell (1988) 3.91
Polarity-specific activities of retinoic acid receptors determined by a co-repressor. Nature (1995) 3.90
Determinants of coactivator LXXLL motif specificity in nuclear receptor transcriptional activation. Genes Dev (1998) 3.79
Requirement for intrinsic protein tyrosine kinase in the immediate and late actions of the EGF receptor. Nature (1987) 3.75
Co-activators and co-repressors in the integration of transcriptional responses. Curr Opin Cell Biol (1998) 3.51
Combinatorial roles of the nuclear receptor corepressor in transcription and development. Cell (2000) 3.47
Retinoic acid and thyroid hormone induce gene expression through a common responsive element. Nature (1988) 3.42
Positive and negative regulation of gene transcription by a retinoic acid-thyroid hormone receptor heterodimer. Cell (1989) 3.24
Pituitary lineage determination by the Prophet of Pit-1 homeodomain factor defective in Ames dwarfism. Nature (1996) 3.21
I-POU: a POU-domain protein that inhibits neuron-specific gene activation. Nature (1991) 3.15
Allosteric effects of Pit-1 DNA sites on long-term repression in cell type specification. Science (2000) 3.14
Functional independence of the epidermal growth factor receptor from a domain required for ligand-induced internalization and calcium regulation. Cell (1989) 3.12
Transcriptional activation by NF-kappaB requires multiple coactivators. Mol Cell Biol (1999) 3.11
ETO, a target of t(8;21) in acute leukemia, interacts with the N-CoR and mSin3 corepressors. Mol Cell Biol (1998) 3.06
Nuclear receptor coactivators. Curr Opin Cell Biol (1997) 2.96
The histone deacetylase-3 complex contains nuclear receptor corepressors. Proc Natl Acad Sci U S A (2000) 2.92
Molecular determinants of nuclear receptor-corepressor interaction. Genes Dev (1999) 2.92
Ligand-induced transformation by a noninternalizing epidermal growth factor receptor. Science (1990) 2.92
Molecular basis of the little mouse phenotype and implications for cell type-specific growth. Nature (1993) 2.83
Role of transcription factors Brn-3.1 and Brn-3.2 in auditory and visual system development. Nature (1996) 2.81
The POU-specific domain of Pit-1 is essential for sequence-specific, high affinity DNA binding and DNA-dependent Pit-1-Pit-1 interactions. Cell (1990) 2.78
Identification of human glucocorticoid receptor complementary DNA clones by epitope selection. Science (1985) 2.77
Expression cloning of human EGF receptor complementary DNA: gene amplification and three related messenger RNA products in A431 cells. Science (1984) 2.75
Interactions controlling the assembly of nuclear-receptor heterodimers and co-activators. Nature (1998) 2.65
Pitx2 regulates lung asymmetry, cardiac positioning and pituitary and tooth morphogenesis. Nature (1999) 2.64
Nuclear integration of JAK/STAT and Ras/AP-1 signaling by CBP and p300. Proc Natl Acad Sci U S A (1997) 2.63
Calcium-regulated phosphorylation within the leucine zipper of C/EBP beta. Science (1992) 2.61
SAP30, a component of the mSin3 corepressor complex involved in N-CoR-mediated repression by specific transcription factors. Mol Cell (1998) 2.60
Splice commitment dictates neuron-specific alternative RNA processing in calcitonin/CGRP gene expression. Cell (1987) 2.58
Diverse signaling pathways modulate nuclear receptor recruitment of N-CoR and SMRT complexes. Proc Natl Acad Sci U S A (1998) 2.55
POU domain family values: flexibility, partnerships, and developmental codes. Genes Dev (1997) 2.48
A nuclear hormone receptor corepressor mediates transcriptional silencing by receptors with distinct repression domains. Mol Cell Biol (1996) 2.47
Regulation of retinoid signalling by receptor polarity and allosteric control of ligand binding. Nature (1994) 2.43
Pituitary cell phenotypes involve cell-specific Pit-1 mRNA translation and synergistic interactions with other classes of transcription factors. Genes Dev (1990) 2.41
Biosynthesis of lysosomal hydrolases: their synthesis in bound polysomes and the role of co- and post-translational processing in determining their subcellular distribution. J Cell Biol (1982) 2.37
A family of LIM domain-associated cofactors confer transcriptional synergism between LIM and Otx homeodomain proteins. Genes Dev (1997) 2.35
Calcitonin/calcitonin gene-related peptide transcription unit: tissue-specific expression involves selective use of alternative polyadenylation sites. Mol Cell Biol (1984) 2.35
Activation of cell-specific expression of rat growth hormone and prolactin genes by a common transcription factor. Science (1988) 2.34
Protein kinase C phosphorylation at Thr 654 of the unoccupied EGF receptor and EGF binding regulate functional receptor loss by independent mechanisms. Cell (1986) 2.31
Signal-specific co-activator domain requirements for Pit-1 activation. Nature (1998) 2.22
Domain structure of human glucocorticoid receptor and its relationship to the v-erb-A oncogene product. Nature (1986) 2.18
Regulation of somatic growth by the p160 coactivator p/CIP. Proc Natl Acad Sci U S A (2000) 2.17
The role of tyrosine kinase activity in endocytosis, compartmentation, and down-regulation of the epidermal growth factor receptor. J Biol Chem (1991) 2.15
Analysis of deletions of the carboxyl terminus of the epidermal growth factor receptor reveals self-phosphorylation at tyrosine 992 and enhanced in vivo tyrosine phosphorylation of cell substrates. J Biol Chem (1990) 2.13
Molecular cloning of a brain-specific calcium/calmodulin-dependent protein kinase. Proc Natl Acad Sci U S A (1987) 2.13
A c-erb-A binding site in rat growth hormone gene mediates trans-activation by thyroid hormone. Nature (1987) 2.11
Differential orientations of the DNA-binding domain and carboxy-terminal dimerization interface regulate binding site selection by nuclear receptor heterodimers. Genes Dev (1993) 2.11
Pitx2 determines left-right asymmetry of internal organs in vertebrates. Nature (1998) 2.10
Differential use of CREB binding protein-coactivator complexes. Science (1998) 2.10
Identification of a seven transmembrane helix receptor for corticotropin-releasing factor and sauvagine in mammalian brain. Neuron (1993) 2.10
Ligand-induced endocytosis of the EGF receptor is blocked by mutational inactivation and by microinjection of anti-phosphotyrosine antibodies. Cell (1988) 2.08
Multistep signaling requirements for pituitary organogenesis in vivo. Genes Dev (1998) 2.02
Nuclear integration of glucocorticoid receptor and nuclear factor-kappaB signaling by CREB-binding protein and steroid receptor coactivator-1. J Biol Chem (1998) 2.02
Tst-1/Oct-6/SCIP regulates a unique step in peripheral myelination and is required for normal respiration. Genes Dev (1996) 2.02
Phosphorylation of the nuclear receptor SF-1 modulates cofactor recruitment: integration of hormone signaling in reproduction and stress. Mol Cell (1999) 2.01
Developmental expression of mouse steroidogenic factor-1, an essential regulator of the steroid hydroxylases. Mol Endocrinol (1994) 2.00
Epidermal growth factor rapidly stimulates prolactin gene transcription. Nature (1982) 1.97
Alternative RNA processing: determining neuronal phenotype. Science (1984) 1.97
Wilms' tumor 1 and Dax-1 modulate the orphan nuclear receptor SF-1 in sex-specific gene expression. Cell (1998) 1.91
Deletion of crhr2 reveals an anxiolytic role for corticotropin-releasing hormone receptor-2. Nat Genet (2000) 1.90
Ligand-induced internalization of the epidermal growth factor receptor is mediated by multiple endocytic codes analogous to the tyrosine motif found in constitutively internalized receptors. J Biol Chem (1993) 1.88
Role of the Bicoid-related homeodomain factor Pitx1 in specifying hindlimb morphogenesis and pituitary development. Genes Dev (1999) 1.88
Steroid receptor-mediated inhibition of rat prolactin gene expression does not require the receptor DNA-binding domain. Cell (1988) 1.87
POU-domain proteins Pit-1 and Oct-1 interact to form a heteromeric complex and can cooperate to induce expression of the prolactin promoter. Genes Dev (1991) 1.84
Alternative production of calcitonin and CGRP mRNA is regulated at the calcitonin-specific splice acceptor. Nature (1989) 1.84
Requirement for Brn-3.0 in differentiation and survival of sensory and motor neurons. Nature (1996) 1.84
Nuclear receptor steroidogenic factor 1 regulates the müllerian inhibiting substance gene: a link to the sex determination cascade. Cell (1994) 1.83
Control of alternative pre-mRNA splicing by distributed pentameric repeats. Proc Natl Acad Sci U S A (1997) 1.82
Pit-1-dependent expression of the receptor for growth hormone releasing factor mediates pituitary cell growth. Nature (1993) 1.80
Infectious and selectable retrovirus containing an inducible rat growth hormone minigene. Science (1984) 1.80
A complex of nuclear proteins mediates SR protein binding to a purine-rich splicing enhancer. Proc Natl Acad Sci U S A (1996) 1.80
Brn-3.0: a POU-domain protein expressed in the sensory, immune, and endocrine systems that functions on elements distinct from known octamer motifs. Proc Natl Acad Sci U S A (1993) 1.79
POU-domain proteins: structure and function of developmental regulators. Curr Opin Cell Biol (1993) 1.79
Development and survival of the endocrine hypothalamus and posterior pituitary gland requires the neuronal POU domain factor Brn-2. Genes Dev (1995) 1.78
P-Lim, a LIM homeodomain factor, is expressed during pituitary organ and cell commitment and synergizes with Pit-1. Proc Natl Acad Sci U S A (1995) 1.77
Control of calcitonin/calcitonin gene-related peptide pre-mRNA processing by constitutive intron and exon elements. Mol Cell Biol (1993) 1.76
Multiple cell type-specific proteins differentially regulate target sequence recognition by the alpha retinoic acid receptor. Cell (1990) 1.75