Published in Br J Radiol on March 01, 1975
Serum concentration measurements in man of the radiosensitizer Ro-07-0582: some preliminary results. Br J Cancer (1975) 2.39
Metronidazole (Flagyl): characterization as a cytotoxic drug specific for hypoxic tumour cells. Br J Cancer (1976) 1.77
Hypoxic cell radiosensitizers and local control by X-ray of a transplanted tumour in mice. Br J Cancer (1977) 1.31
Influence of tumour size on radiosensitization by misonidazole. Br J Cancer Suppl (1978) 1.24
Testing of hypoxic cell radiosensitizers in vivo. Br J Cancer Suppl (1978) 1.16
Changes in nerve conduction velocity in the mouse after acute and chronic administration of nitroimidazoles. Br J Cancer (1979) 0.95
Respiration of mammalian cells at low concentrations of oxygen: I. Effect of hypoxic-cell radiosensitizing drugs. Br J Cancer Suppl (1978) 0.83
The effect of misonidazole on the radiation response of clonogenic human pancreatic carcinoma cells. Br J Cancer Suppl (1978) 0.80
Cytotoxic and radiosensitizing effects of hypoxic cell sensitizers on EMT6 mouse mammary tumour cells in vivo and in vitro. Br J Cancer Suppl (1978) 0.78
Nitropyrrole radiosensitizers: structure function relationships. Br J Cancer Suppl (1978) 0.75
Effect of acute and chronic misonidazole administration on peripheral-nerve electrophysiology in mice. Br J Cancer (1980) 0.75
Principles and applications of ultrasound backscatter microscopy. IEEE Trans Ultrason Ferroelectr Freq Control (1993) 2.98
Mentors and role models for women in academic medicine. West J Med (1991) 2.83
Part-time faculty in academic medicine: present status and future challenges. Ann Intern Med (1993) 2.67
An in vitro assay to measure the viability of KHT tumor cells not previously exposed to culture conditions. Radiat Res (1974) 2.62
Increased cell killing by metronidazole and nitrofurazone of hypoxic compared to aerobic mammalian cells. Cancer Res (1976) 2.26
Evidence for dark-reactivation of ultraviolet light damage in mouse L cells. Radiat Res (1967) 1.47
The Physical State of Viral Nucleic Acid and the Sensitivity of Viruses to Ultraviolet Light. Biophys J (1965) 1.29
Molecular mechanisms for the hypoxia-dependent activation of 3-amino-1,2,4-benzotriazine-1,4-dioxide (SR 4233). Biochem Pharmacol (1988) 1.28
Presence of a heterozygous substitution and its relationship to DT-diaphorase activity. Br J Cancer (1995) 1.28
The interaction of caffeine with ultra-violet-light-irradiated DNA. Int J Radiat Biol Relat Stud Phys Chem Med (1970) 1.27
Differences in the toxicity and metabolism of the 2-nitroimidazole misonidazole (Ro-07-0582) in HeLa and Chinese hamster ovary cells. Cancer Res (1978) 1.19
A polymorphism in NAD(P)H:quinone oxidoreductase (NQO1): relationship of a homozygous mutation at position 609 of the NQO1 cDNA to NQO1 activity. Br J Cancer (1996) 1.19
An experimental and analytical study of oxygen depletion in stirred cell suspensions. Radiat Res (1980) 1.18
Testing of hypoxic cell radiosensitizers in vivo. Br J Cancer Suppl (1978) 1.16
Nascent DNA synthesis in ultraviolet light-irradiated mouse L cells. Biochim Biophys Acta (1972) 1.15
Ultraviolet irradiation of mouse L cells: effects on DNA synthesis and progression through the cell cycle. Radiat Res (1968) 1.14
A strategy to promote research-based nursing care: effects on childbirth outcomes. Res Nurs Health (1996) 1.12
Effects of caffeine on ultraviolet-irradiated mouse L cells. Radiat Res (1969) 1.10
Competency to decide about treatment or research: an overview of some empirical data. Int J Law Psychiatry (1982) 1.08
Pharmacology and toxicology of sensitizers: mechanism studies. Int J Radiat Oncol Biol Phys (1984) 1.08
Small ribosomal ribonucleic acid species of Saccharomyces cerevisiae. J Bacteriol (1971) 1.08
A study of doxorubicin loading onto and release from sulfopropyl dextran ion-exchange microspheres. J Control Release (2001) 1.07
DT-diaphorase activity and mitomycin C sensitivity in non-transformed cell strains derived from members of a cancer-prone family. Carcinogenesis (1991) 1.05
Activity of mitomycin C for aerobic and hypoxic cells in vitro and in vivo. Cancer Res (1983) 1.05
Effects of dimethyl sulfoxide and hypoxic cell radiosensitizers on the radiation response of the KHT murine tumor in vivo. Radiat Res (1977) 1.04
Deficient activation by a human cell strain leads to mitomycin resistance under aerobic but not hypoxic conditions. Br J Cancer (1989) 1.03
Human posterior cricoarytenoid muscle compartments. Anatomy and mechanics. Arch Otolaryngol Head Neck Surg (1996) 1.01
An early labor assessment program: a randomized, controlled trial. Birth (1998) 0.98
The metabolism and pharmacokinetics of the hypoxic cell radiosensitizer and cytotoxic agent, misonidazole, in C3H mice. Radiat Res (1981) 0.97
Response of a rat brain tumor to fractionated therapy with low doses of BCNU and irradiation. Int J Radiat Oncol Biol Phys (1979) 0.97
Nascent DNA synthesis in ultraviolet light-irradiated mouse, human and Chinese hamster cells. Biophys J (1974) 0.96
Prediction of outcome after rectus femoris surgery in cerebral palsy: the role of cocontraction of the rectus femoris and vastus lateralis. J Pediatr Orthop (1999) 0.96
Outcome of 51 cases of unilateral locked cervical facets: interspinous braided cable for lateral mass plate fusion compared with interspinous wire and facet wiring with iliac crest. J Neurosurg (1999) 0.94
Screening for the mutagenicity of nitro-group containing hypoxic cell radiosensitizers using Salmonella typhimurium strains TA 100 and TA98. Mutat Res (1978) 0.93
Diagnosis of an ACL disruption with KT-1000 arthrometer measurements. Knee Surg Sports Traumatol Arthrosc (1993) 0.93
Targeting radiosensitizers to DNA by attachment of an intercalating group: nitroimidazole-linked phenanthridines. Radiat Res (1991) 0.93
A competency-based parent training program for child abusers. J Consult Clin Psychol (1981) 0.92
Sulphydryls, ascorbate and oxygen as modifiers of the toxicity and metabolism of misonidazole in vitro. Br J Cancer (1980) 0.92
Ultraviolet-light irradiation of mouse L cells: effects on cells in the DNA synthesis phase. Radiat Res (1969) 0.91
The effect of individualized professional support on duration of breastfeeding: a randomized controlled trial. J Hum Lact (2000) 0.90
The effects of board composition and structure on hospital performance. Hosp Health Serv Adm (1979) 0.90
Mechanism of ultrasound enhanced porphyrin cytotoxicity. Part I: A search for free radical effects. Ultrasound Med Biol (1997) 0.88
Surgical therapy for tremor in multiple sclerosis: an evaluation of outcome measures. Neurology (2001) 0.88
Constitutive expression of P-glycoprotein as a determinant of loading with fluorescent calcium probes. Cytometry (1994) 0.88
DNA-targeted 2-nitroimidazoles: in vitro and in vivo studies. Br J Cancer (1994) 0.88
5-Fluorouracil infusions and fractionated doses of radiation: studies with a murine squamous cell carcinoma. Int J Radiat Oncol Biol Phys (1987) 0.88
Restricted specificity of intermolecular spreading to endogenous La (SS-B) and 60 kDa Ro (SS-A) in experimental autoimmunity. Scand J Immunol (2002) 0.87
The survival of synchronized L cells after ultraviolet irradiation. Radiat Res (1966) 0.87
Modification of the cytotoxic activity of mitomycin C by oxygen and ascorbic acid in Chinese hamster ovary cells and a repair-deficient mutant. Cancer Res (1986) 0.87
Studies on the mechanism of resistance to mitomycin C and porfiromycin in a human cell strain derived from a cancer-prone individual. Biochem Pharmacol (1991) 0.87
Identification of two major reduction products of the hypoxic cell toxin 3-amino-1,2,4-benzotriazine-1,4-dioxide. Biochem Pharmacol (1986) 0.86
Mechanistic studies of enhanced in vitro radiosensitization and hypoxic cell cytotoxicity by targeting radiosensitizers to DNA via intercalation. Int J Radiat Oncol Biol Phys (1992) 0.86
Measurement of low levels of oxygen and their effect on respiration in cell suspensions maintained in an open system. Radiat Res (1986) 0.85
Spontaneous phenotypic and karyotypic progression in the SV40 transfected cell line SVG during prolonged passage in vitro. J Neurooncol (1990) 0.85
Growth delay in a murine squamous cell tumor after local radiation and concurrent infusional 5-fluorouracil treatment. Int J Radiat Oncol Biol Phys (1986) 0.85
Effect of 1-methyl-2-nitrosoimidazole on intracellular thiols and calcium levels in Chinese hamster ovary cells. Biochem Pharmacol (1991) 0.84
Influence of fractionation schedules on the response of a rat brain tumor to therapy with BCNU and radiation. Int J Radiat Oncol Biol Phys (1980) 0.84
Mechanism of the selective hypoxic cytotoxicity of 1-methyl-2-nitroimidazole. Biochem Pharmacol (1994) 0.84
Three-dimensional characteristics of cartilaginous and bony components of dysplastic hips in children: three-dimensional computed tomography quantitative analysis. J Pediatr Orthop (1997) 0.84
Efficacy of continuous treatment with radiation in a rat brain-tumor model. J Neurosurg (1981) 0.84
Preparation, toxicity and mutagenicity of 1-methyl-2-nitrosoimidazole. A toxic 2-nitroimidazole reduction product. Biochem Pharmacol (1988) 0.84
A toxicity study of daily dose metronidazole with pelvic irradiation. Cancer Clin Trials (1980) 0.83
Oxygen and exposure kinetics as factors influencing the cytotoxicity of porfiromycin, a mitomycin C analogue, in Chinese hamster ovary cells. Cancer Res (1988) 0.83
Use of a high frequency ultrasound microscope to image the action of 2-nitroimidazoles in multicellular spheroids. Br J Cancer (1992) 0.83
The oxygen dependence of the reduction of nitroimidazoles in a radiolytic model system. Int J Radiat Oncol Biol Phys (1984) 0.82
Protein-protein interaction of the Ro-ribonucleoprotein particle using multiple antigenic peptides. Mol Immunol (2000) 0.82
The anterior cruciate ligament in controlling axial rotation. An evaluation of its effect. Am J Sports Med (1994) 0.82
NLP-1: a DNA intercalating hypoxic cell radiosensitizer and cytotoxin. Int J Radiat Oncol Biol Phys (1989) 0.81
Characterization of a set of Chinese hamster ovary variant cell lines demonstrating differing sensitivity to mitomycin C. Oncol Res (1993) 0.81
Aortic "recoarctation" at rest versus at exercise in children as evaluated by stress Doppler echocardiography after a "good" operative result. Am J Cardiol (1993) 0.81
Effects of caffeine on L-cells exposed to mitomycin C. Cancer Res (1970) 0.81
A multidisciplinary study of the 'yips' phenomenon in golf: An exploratory analysis. Sports Med (2000) 0.81
Identification of novel coding mutation in C1qA gene in an African-American pedigree with lupus and C1q deficiency. Lupus (2012) 0.80
The effects of phleomycin on mouse L-cells. Cancer Res (1971) 0.80
Oxygen tension, cellular respiration, and redox state as variables influencing the cytotoxicity of the radiosensitizer misonidazole. Radiat Res (1982) 0.80
Effect of hypoxia on the accumulation of technetium-99m-glucarate and technetium-99m-gluconate by Chinese hamster ovary cells in vitro. J Nucl Med (1993) 0.80
An analysis of changes in oxygen tension in stirred cellular suspensions under conditions of radiolytic and cellular consumption. Cancer Clin Trials (1980) 0.80
Brain tumor therapy: prospects for combining BCNU with conventional radiotherapy schedules. Int J Radiat Oncol Biol Phys (1981) 0.80
Assessment of the relationship between genotypic status of a DT-diaphorase point mutation and enzymatic activity. Br J Cancer (2000) 0.80
BRU59-21, a second-generation 99mTc-labeled 2-nitroimidazole for imaging hypoxia in tumors. J Nucl Med (2000) 0.80
Differential cell death in immortalized and non-immortalized cells at confluency. Oncogene (1996) 0.80
Accumulation of technetium-99m glucarate: in vitro cell cultures and in vivo tumour models. Nucl Med Commun (2003) 0.79
Studies of 99mTc-BnAO (HL-91): a non-nitroaromatic compound for hypoxic cell detection. Int J Radiat Oncol Biol Phys (1998) 0.79
In vitro and in vivo evaluation of a technetium-99m-labeled 2-nitroimidazole (BMS181321) as a marker of tumor hypoxia. J Nucl Med (1996) 0.79
Semi-automated digital image analysis of patellofemoral joint space width from lateral knee radiographs. Skeletal Radiol (2005) 0.79
Transfection of COS-1 cells with DT-diaphorase cDNA: role of a base change at position 609. Br J Cancer (1998) 0.79
Metastatic cardiac angiosarcoma of the cervical spine. Case report. Spine (Phila Pa 1976) (1999) 0.79
Prediction of muscle recruitment and its effect on joint reaction forces during knee exercises. Ann Biomed Eng (1998) 0.79
2-Hydroxylaminoimidazoles--unstable intermediates in the reduction of 2-nitroimidazoles. Biochem Pharmacol (1984) 0.79
Isolation and characterization of revertants of the mammalian temperature sensitive leucyl-tRNA synthetase mutant tsHl. J Cell Physiol (1979) 0.79
Role of a DT-diaphorase mutation in the response of anal canal carcinoma to radiation, 5-fluorouracil, and mitomycin C. Int J Radiat Oncol Biol Phys (1998) 0.79
Cell cycle specific recovery from fractionated exposures of ultraviolet light. Radiat Res (1973) 0.79
Isolation and characterization of a cell line resistant to 5-[3-(2-nitro-1-imidazoyl)-propyl]-phenanthridinium bromide (2-NLP-3), a DNA-intercalating hypoxic cell radiosensitizer and cytotoxin. Biochem Pharmacol (1995) 0.78
Depletion of intracellular glutathione by 1-methyl-2-nitrosoimidazole. Int J Radiat Oncol Biol Phys (1992) 0.78
Failure of 2-deoxy-D-glucose and 5-thio-D-glucose to kill hypoxic cells of two murine tumors. Cancer Res (1983) 0.78
Comparison of the accumulation and efflux kinetics of technetium-99m sestamibi and technetium-99m tetrofosmin in an MRP-expressing tumour cell line. Eur J Nucl Med (2000) 0.78
1-Methyl-2-nitrosoimidazole: cytotoxic and glutathione depleting capabilities. Int J Radiat Oncol Biol Phys (1989) 0.78
Differential cytotoxicity of diaziquone toward Chinese hamster ovary cells under hypoxic and aerobic exposure conditions. Cancer Res (1990) 0.78
Role of Ia antigens in graft vs. host reactions. II. Molecular and functional analysis of T cell alloreactivity by the characterization of host Ia antigens on alloactivated donor T cells. J Exp Med (1982) 0.78