Published in Mol Cell Biol on April 01, 2001
Yeast Gal4: a transcriptional paradigm revisited. EMBO Rep (2006) 1.73
Leucine biosynthesis in fungi: entering metabolism through the back door. Microbiol Mol Biol Rev (2003) 1.66
Mechanisms and evolution of control logic in prokaryotic transcriptional regulation. Microbiol Mol Biol Rev (2009) 1.25
SUMO-mediated inhibition of glucocorticoid receptor synergistic activity depends on stable assembly at the promoter but not on DAXX. Mol Endocrinol (2008) 1.12
A downstream regulatory element located within the coding sequence mediates autoregulated expression of the yeast fatty acid synthase gene FAS2 by the FAS1 gene product. Nucleic Acids Res (2001) 1.00
New and Redesigned pRS Plasmid Shuttle Vectors for Genetic Manipulation of Saccharomycescerevisiae. G3 (Bethesda) (2012) 0.96
Control and signal processing by transcriptional interference. Mol Syst Biol (2009) 0.94
Gcn4 occupancy of open reading frame regions results in the recruitment of chromatin-modifying complexes but not the mediator complex. EMBO Rep (2003) 0.89
Evolution of biological interaction networks: from models to real data. Genome Biol (2011) 0.85
A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae. Genetics (1989) 105.30
Genome-wide location and function of DNA binding proteins. Science (2000) 31.25
Transcriptional activation by recruitment. Nature (1997) 10.44
Alteration of nucleosome structure as a mechanism of transcriptional regulation. Annu Rev Biochem (1998) 8.86
Yeast Gcn5 functions in two multisubunit complexes to acetylate nucleosomal histones: characterization of an Ada complex and the SAGA (Spt/Ada) complex. Genes Dev (1997) 8.35
Stimulation of GAL4 derivative binding to nucleosomal DNA by the yeast SWI/SNF complex. Science (1994) 7.17
Negative effect of the transcriptional activator GAL4. Nature (1988) 7.15
Nucleosome disruption and enhancement of activator binding by a human SW1/SNF complex. Nature (1994) 6.55
Isolation of the yeast regulatory gene GAL4 and analysis of its dosage effects on the galactose/melibiose regulon. Proc Natl Acad Sci U S A (1982) 6.22
Upstream activation sites of the CYC1 gene of Saccharomyces cerevisiae are active when inverted but not when placed downstream of the "TATA box". Proc Natl Acad Sci U S A (1984) 4.88
Five SWI/SNF gene products are components of a large multisubunit complex required for transcriptional enhancement. Proc Natl Acad Sci U S A (1994) 4.49
The SWI-SNF complex: a chromatin remodeling machine? Trends Biochem Sci (1995) 4.20
Transcription factor ATF interacts with the TATA factor to facilitate establishment of a preinitiation complex. Cell (1988) 4.15
Selective inhibition of activated but not basal transcription by the acidic activation domain of VP16: evidence for transcriptional adaptors. Cell (1990) 3.31
Facilitated binding of GAL4 and heat shock factor to nucleosomal templates: differential function of DNA-binding domains. Genes Dev (1991) 3.14
Absolute mRNA levels and transcriptional initiation rates in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (1996) 2.88
Activation domains of stably bound GAL4 derivatives alleviate repression of promoters by nucleosomes. Cell (1991) 2.83
The acidic activation domains of the GCN4 and GAL4 proteins are not alpha helical but form beta sheets. Cell (1993) 2.80
Analysis of the Kluyveromyces lactis positive regulatory gene LAC9 reveals functional homology to, but sequence divergence from, the Saccharomyces cerevisiae GAL4 gene. Nucleic Acids Res (1986) 2.76
Recruitment of the SWI/SNF chromatin remodeling complex by transcriptional activators. Genes Dev (1999) 2.48
Nucleosome core displacement in vitro via a metastable transcription factor-nucleosome complex. Science (1992) 2.40
Evolution of a fungal regulatory gene family: the Zn(II)2Cys6 binuclear cluster DNA binding motif. Fungal Genet Biol (1997) 2.40
Regulation of basal and induced levels of the MEL1 transcript in Saccharomyces cerevisiae. Mol Cell Biol (1984) 2.08
Detection of leucine-independent DNA site occupancy of the yeast Leu3p transcriptional activator in vivo. Mol Cell Biol (1995) 1.79
LEU3 of Saccharomyces cerevisiae activates multiple genes for branched-chain amino acid biosynthesis by binding to a common decanucleotide core sequence. Mol Cell Biol (1988) 1.72
Cooperative DNA binding of p53 with TFIID (TBP): a possible mechanism for transcriptional activation. Genes Dev (1993) 1.45
How do "Zn2 cys6" proteins distinguish between similar upstream activation sites? Comparison of the DNA-binding specificity of the GAL4 protein in vitro and in vivo. J Biol Chem (1993) 1.45
The nucleotide sequence of the yeast MEL1 gene. Nucleic Acids Res (1985) 1.28
Functional homology between the yeast regulatory proteins GAL4 and LAC9: LAC9-mediated transcriptional activation in Kluyveromyces lactis involves protein binding to a regulatory sequence homologous to the GAL4 protein-binding site. Mol Cell Biol (1987) 1.22
Characterization of a yeast replication origin (ars2) and construction of stable minichromosomes containing cloned yeast centromere DNA (CEN3). Gene (1981) 1.21
Enhancer and silencerlike sites within the transcribed portion of a Ty2 transposable element of Saccharomyces cerevisiae. Mol Cell Biol (1989) 1.17
A transcriptional activator is located in the coding region of the yeast PGK gene. Nucleic Acids Res (1987) 1.16
The activation domain of GAL4 protein mediates cooperative promoter binding with general transcription factors in vivo. Proc Natl Acad Sci U S A (1995) 1.08
The DNA binding and activation domains of Gal4p are sufficient for conveying its regulatory signals. Mol Cell Biol (1997) 0.97
Yeast intragenic transcriptional control: activation and repression sites within the coding region of the Saccharomyces cerevisiae LPD1 gene. Mol Cell Biol (1994) 0.95
Downstream activating sequence within the coding region of a yeast gene: specific binding in vitro of RAP1 protein. Mol Gen Genet (1992) 0.93
The chromatin structure of the GAL1 promoter forms independently of Reb1p in Saccharomyces cerevisiae. Mol Gen Genet (1998) 0.91
Transcriptionally active SV40 minichromosomes are restriction enzyme sensitive and contain a nucleosome-free origin region. Nucleic Acids Res (1986) 0.83
Isolation of the yeast regulatory gene GAL4 and analysis of its dosage effects on the galactose/melibiose regulon. Proc Natl Acad Sci U S A (1982) 6.22
Genetic immunization is a simple method for eliciting an immune response. Nature (1992) 5.30
Gene transfer in Cryptococcus neoformans by use of biolistic delivery of DNA. J Bacteriol (1993) 5.14
Interaction of thyroid-hormone receptor with a conserved transcriptional mediator. Nature (1995) 3.27
Overview of adult health measures fielded in Rand's health insurance study. Med Care (1979) 3.20
Genetic evidence that an activation domain of GAL4 does not require acidity and may form a beta sheet. Cell (1993) 3.05
The acidic activation domains of the GCN4 and GAL4 proteins are not alpha helical but form beta sheets. Cell (1993) 2.80
Analysis of the Kluyveromyces lactis positive regulatory gene LAC9 reveals functional homology to, but sequence divergence from, the Saccharomyces cerevisiae GAL4 gene. Nucleic Acids Res (1986) 2.76
Interaction of positive and negative regulatory proteins in the galactose regulon of yeast. Cell (1987) 2.75
Release of proteins and peptides from fusion proteins using a recombinant plant virus proteinase. Anal Biochem (1994) 2.71
The 19S regulatory particle of the proteasome is required for efficient transcription elongation by RNA polymerase II. Mol Cell (2001) 2.45
GAL4 interacts with TATA-binding protein and coactivators. Mol Cell Biol (1995) 2.10
Nondissociation of GAL4 and GAL80 in vivo after galactose induction. Science (1992) 1.98
Alterations in a yeast protein resembling HIV Tat-binding protein relieve requirement for an acidic activation domain in GAL4. Nature (1992) 1.94
The 19S regulatory complex of the proteasome functions independently of proteolysis in nucleotide excision repair. Mol Cell (1999) 1.92
Protection against mycoplasma infection using expression-library immunization. Nature (1995) 1.88
A highly conserved ATPase protein as a mediator between acidic activation domains and the TATA-binding protein. Nature (1995) 1.83
Genome-directed primers for selective labeling of bacterial transcripts for DNA microarray analysis. Nat Biotechnol (2000) 1.83
Introduction of foreign genes into tissues of living mice by DNA-coated microprojectiles. Proc Natl Acad Sci U S A (1991) 1.80
Toward cell-targeting gene therapy vectors: selection of cell-binding peptides from random peptide-presenting phage libraries. Nat Med (1996) 1.79
Linear expression elements: a rapid, in vivo, method to screen for gene functions. Nat Biotechnol (1999) 1.76
Subcellular localization, stoichiometry, and protein levels of 26 S proteasome subunits in yeast. J Biol Chem (1999) 1.69
Functional domains of the yeast regulatory protein GAL4. Proc Natl Acad Sci U S A (1986) 1.64
Evidence for two modes of cooperative DNA binding in vivo that do not involve direct protein-protein interactions. Curr Biol (1998) 1.60
Altering DNA-binding specificity of GAL4 requires sequences adjacent to the zinc finger. Nature (1989) 1.57
Biolistic nuclear transformation of Saccharomyces cerevisiae and other fungi. Curr Genet (1990) 1.54
Analysis of the galactose signal transduction pathway in Saccharomyces cerevisiae: interaction between Gal3p and Gal80p. Mol Cell Biol (1996) 1.51
Hookworms in the Americas: An alternative to trans-Pacific contact. Parasitol Today (1996) 1.49
How do "Zn2 cys6" proteins distinguish between similar upstream activation sites? Comparison of the DNA-binding specificity of the GAL4 protein in vitro and in vivo. J Biol Chem (1993) 1.45
The 19S complex of the proteasome regulates nucleotide excision repair in yeast. Genes Dev (2001) 1.36
Crystal structure of a conserved protease that binds DNA: the bleomycin hydrolase, Gal6. Science (1995) 1.34
GAL4 of Saccharomyces cerevisiae activates the lactose-galactose regulon of Kluyveromyces lactis and creates a new phenotype: glucose repression of the regulon. Mol Cell Biol (1987) 1.33
Isolation and characterization of SUG2. A novel ATPase family component of the yeast 26 S proteasome. J Biol Chem (1996) 1.31
Evidence that Gal11 protein is a target of the Gal4 activation domain in the mediator. Biochemistry (2001) 1.27
Interaction between transcriptional activator protein LAC9 and negative regulatory protein GAL80. Mol Cell Biol (1989) 1.19
GAL4 mutations that separate the transcriptional activation and GAL80-interactive functions of the yeast GAL4 protein. Genetics (1990) 1.19
Manipulations of endosperm balance number overcome crossing barriers between diploid solanum species. Science (1982) 1.16
Biological features of genetic immunization. Vaccine (1997) 1.14
Butyrate-inducible and tumor-restricted gene expression by adenovirus vectors. Cancer Gene Ther (1994) 1.11
Efficacy of etodolac for the treatment of osteoarthritis of the hip joints in dogs. J Am Vet Med Assoc (1999) 1.06
The Gal4 activation domain binds Sug2 protein, a proteasome component, in vivo and in vitro. J Biol Chem (2001) 1.02
Evidence that proteolysis of Gal4 cannot explain the transcriptional effects of proteasome ATPase mutations. J Biol Chem (2001) 1.02
Quantitative analysis of the immunopotency of genetically transfected dendritic cells. Proc Natl Acad Sci U S A (1998) 0.99
A single GAL4 dimer can maximally activate transcription under physiological conditions. Proc Natl Acad Sci U S A (1995) 0.98
New chemistry for the study of multiprotein complexes: the six-histidine tag as a receptor for a protein crosslinking reagent. Chem Biol (1996) 0.97
The DNA binding and activation domains of Gal4p are sufficient for conveying its regulatory signals. Mol Cell Biol (1997) 0.97
Transcription of multiple copies of the yeast GAL7 gene is limited by specific factors in addition to GAL4. Mol Gen Genet (1987) 0.97
Semaphorin III can repulse and inhibit adult sensory afferents in vivo. Nat Med (1997) 0.94
Alterations in the GAL4 DNA-binding domain can affect transcriptional activation independent of DNA binding. J Biol Chem (1998) 0.93
Production of monoclonal antibodies by genetic immunization. Biotechniques (1994) 0.89
The unusual active site of Gal6/bleomycin hydrolase can act as a carboxypeptidase, aminopeptidase, and peptide ligase. Cell (1998) 0.88
Genetic live vaccines mimic the antigenicity but not pathogenicity of live viruses. DNA Cell Biol (1999) 0.88
Yeast bleomycin hydrolase is a DNA-binding cysteine protease. Identification, purification, biochemical characterization. J Biol Chem (1994) 0.86
A combination vaccine confers full protection against co-infections with influenza, herpes simplex and respiratory syncytial viruses. Vaccine (2001) 0.85
Potent peptide inhibitors of smooth muscle myosin light chain kinase: mapping of the pseudosubstrate and calmodulin binding domains. Arch Biochem Biophys (1990) 0.85
The cysteine-peptidase bleomycin hydrolase is a member of the galactose regulon in yeast. J Biol Chem (1997) 0.85
Controlled gene gun delivery and expression of DNA within the cornea. Biotechniques (1997) 0.84
Protection against Mycoplasma pulmonis infection by genetic vaccination. DNA Cell Biol (1995) 0.84
Use of carprofen for the treatment of pain and inflammation in dogs. J Am Vet Med Assoc (1997) 0.84
Crystal structure of human bleomycin hydrolase, a self-compartmentalizing cysteine protease. Structure (1999) 0.84
Identification of a phylogenetically conserved Sug1 CAD family member that is differentially expressed in the mouse nervous system. J Neurobiol (1997) 0.82
Rectal ganglioneuroma in a dog. J Am Anim Hosp Assoc (1999) 0.82
Pathogen-derived resistance to viral infection using a negative regulatory molecule. Virology (1987) 0.82
Slow-acting, disease-modifying osteoarthritis agents. Vet Clin North Am Small Anim Pract (1997) 0.82
Application of TEV Protease in Protein Production. Methods Mol Med (1998) 0.82
Selective chemical inactivation of AAA proteins reveals distinct functions of proteasomal ATPases. Chem Biol (2001) 0.80
CADp44: a novel regulatory subunit of the 26S proteasome and the mammalian homolog of yeast Sug2p. Gene (1996) 0.80
Comparison of stance time and velocity as control variables in force plate analysis of dogs. Am J Vet Res (1999) 0.80
Chylothorax associated with constrictive pericarditis in a dog. J Am Vet Med Assoc (1995) 0.78
Development of a Langerhans cell-targeted gene therapy format using a dendritic cell-specific promoter. Gene Ther (2001) 0.78
Income group differences in relationships among survey measures of physical and mental health. Health Serv Res (1976) 0.78
Affinity purification of proteins binding to GST fusion proteins. Curr Protoc Mol Biol (2001) 0.77
Induction of Th2-directed immune responses by IL-4-transduced dendritic cells in mice. Vaccine (2000) 0.77
Variation of lung density corrections in a typical patient population. Med Dosim (1989) 0.76
Alterations in a yeast protein resembling HIV Tat-binding protein relieve requirement for an acidic activation domain in GAL4. Nature (1993) 0.76
Evaluation of a method for experimental induction of osteoarthritis of the hip joints in dogs. Am J Vet Res (2000) 0.76
Synaptic and neurotransmitter regulation of activity in mammalian hypothalamic magnocellular neurosecretory cells. Prog Brain Res (1992) 0.76
The nucleic acid binding activity of bleomycin hydrolase is involved in bleomycin detoxification. Mol Cell Biol (1998) 0.76
The clinical, cerebrospinal fluid, and histopathologic effects of epidural ketorolac in dogs. Vet Surg (2000) 0.76
Immune responses in baboons vaccinated with HIV-2 genetic expression libraries. J Med Primatol (2002) 0.75
Controlled cross circulation in dogs: effects on donor hemodynamics. Vet Surg (1996) 0.75
The dangers of 'splicing and dicing': on the use of chimeric transcriptional activators in vitro. Chem Biol (1995) 0.75
Pantarsal arthrodesis in dogs and a cat: 11 cases (1983-1991). J Am Vet Med Assoc (1993) 0.75
Eukaryotic gene regulation: simple vs complex models. SAAS Bull Biochem Biotechnol (1991) 0.75
Naivete and need for affection among pedophiles. J Clin Psychol (1992) 0.75
A cognitive approach to validation of the fixated-regressed typology of child molesters. J Clin Psychol (1997) 0.75
Differences between human figure drawings of child molesters and control groups. J Clin Psychol (1986) 0.75
Minimally displaced tibial tuberosity avulsion fracture in nine skeletally immature large breed dogs. Vet Comp Orthop Traumatol (2012) 0.75
Quantitative autoradiography of parathyroid glands in rats with carbon-14-labeled amino acids. J Nucl Med (1987) 0.75
The gastroduodenal effects of buffered aspirin, carprofen, and etodolac in healthy dogs. J Vet Intern Med (1999) 0.75
The preventive dental program in Saskatchewan. Can Dent Hyg (1967) 0.75
The genetics of triploid formation and its relationship to endosperm balance number in potato. Genome (1995) 0.75
Genetic control of Endosperm Balance Number (EBN) in the Solanaceae based on trisomic and mutation analysis. Genome (1996) 0.75
Effects of a prostaglandin E1 analogue, misoprostol, on renal function in dogs receiving nephrotoxic doses of gentamicin. Am J Vet Res (1998) 0.75