Published in Proc Natl Acad Sci U S A on November 01, 1982
Saccharomyces cerevisiae GAL1-GAL10 divergent promoter region: location and function of the upstream activating sequence UASG. Mol Cell Biol (1984) 7.83
A model fungal gene regulatory mechanism: the GAL genes of Saccharomyces cerevisiae. Microbiol Rev (1987) 7.00
Positive regulation in the general amino acid control of Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (1983) 6.93
Use of lacZ fusions to delimit regulatory elements of the inducible divergent GAL1-GAL10 promoter in Saccharomyces cerevisiae. Mol Cell Biol (1984) 6.23
The Saccharomyces cerevisiae MYO2 gene encodes an essential myosin for vectorial transport of vesicles. J Cell Biol (1991) 5.73
Primary structure of the Saccharomyces cerevisiae GAL4 gene. Mol Cell Biol (1984) 5.49
Positive regulatory interactions of the HIS4 gene of Saccharomyces cerevisiae. Mol Cell Biol (1984) 5.08
Isolation and preliminary characterization of the GAL4 gene, a positive regulator of transcription in yeast. Proc Natl Acad Sci U S A (1982) 4.93
Amino terminus of the yeast GAL4 gene product is sufficient for nuclear localization. Proc Natl Acad Sci U S A (1984) 4.90
Specific protein binding to far upstream activating sequences in polymerase II promoters. Proc Natl Acad Sci U S A (1985) 4.85
Yeast regulatory gene GAL3: carbon regulation; UASGal elements in common with GAL1, GAL2, GAL7, GAL10, GAL80, and MEL1; encoded protein strikingly similar to yeast and Escherichia coli galactokinases. Mol Cell Biol (1988) 4.82
Refinement of tools for targeted gene expression in Drosophila. Genetics (2010) 4.53
Identification and structure of four yeast genes (SLY) that are able to suppress the functional loss of YPT1, a member of the RAS superfamily. Mol Cell Biol (1991) 3.68
Control of yeast GAL genes by MIG1 repressor: a transcriptional cascade in the glucose response. EMBO J (1991) 3.56
The PEP4 gene encodes an aspartyl protease implicated in the posttranslational regulation of Saccharomyces cerevisiae vacuolar hydrolases. Mol Cell Biol (1986) 3.30
A fungal family of transcriptional regulators: the zinc cluster proteins. Microbiol Mol Biol Rev (2006) 3.05
Disruption of regulatory gene GAL80 in Saccharomyces cerevisiae: effects on carbon-controlled regulation of the galactose/melibiose pathway genes. Mol Cell Biol (1984) 2.87
Analysis of the Kluyveromyces lactis positive regulatory gene LAC9 reveals functional homology to, but sequence divergence from, the Saccharomyces cerevisiae GAL4 gene. Nucleic Acids Res (1986) 2.76
A liver-specific DNA-binding protein recognizes multiple nucleotide sites in regulatory regions of transthyretin, alpha 1-antitrypsin, albumin, and simian virus 40 genes. Proc Natl Acad Sci U S A (1988) 2.71
Expression of the Saccharomyces cerevisiae inositol-1-phosphate synthase (INO1) gene is regulated by factors that affect phospholipid synthesis. Mol Cell Biol (1986) 2.50
GAL11 protein, an auxiliary transcription activator for genes encoding galactose-metabolizing enzymes in Saccharomyces cerevisiae. Mol Cell Biol (1988) 2.41
Gene organization and regulation in the qa (quinic acid) gene cluster of Neurospora crassa. Microbiol Rev (1985) 2.33
Characterization of a positive regulatory gene, LAC9, that controls induction of the lactose-galactose regulon of Kluyveromyces lactis: structural and functional relationships to GAL4 of Saccharomyces cerevisiae. Mol Cell Biol (1987) 2.29
Interaction of GAL4 and GAL80 gene regulatory proteins in vitro. Mol Cell Biol (1987) 2.26
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GAL4 interacts with TATA-binding protein and coactivators. Mol Cell Biol (1995) 2.10
Regulation of basal and induced levels of the MEL1 transcript in Saccharomyces cerevisiae. Mol Cell Biol (1984) 2.08
Proline-independent binding of PUT3 transcriptional activator protein detected by footprinting in vivo. Mol Cell Biol (1991) 1.98
Sequence of the Saccharomyces GAL region and its transcription in vivo. J Bacteriol (1984) 1.96
Nucleotide sequence of the yeast regulatory gene GAL80. Nucleic Acids Res (1984) 1.91
The HAP3 regulatory locus of Saccharomyces cerevisiae encodes divergent overlapping transcripts. Mol Cell Biol (1988) 1.87
Nucleotide sequence of the transcriptional initiation region of the yeast GAL7 gene. Nucleic Acids Res (1983) 1.77
Overproduction of the GAL1 or GAL3 protein causes galactose-independent activation of the GAL4 protein: evidence for a new model of induction for the yeast GAL/MEL regulon. Mol Cell Biol (1992) 1.73
Isolation and characterization of MOD5, a gene required for isopentenylation of cytoplasmic and mitochondrial tRNAs of Saccharomyces cerevisiae. Mol Cell Biol (1987) 1.67
Isolation and characterization of the RNA2, RNA3, and RNA11 genes of Saccharomyces cerevisiae. Mol Cell Biol (1984) 1.66
Duplicate upstream activating sequences in the promoter region of the Saccharomyces cerevisiae GAL7 gene. Mol Cell Biol (1986) 1.66
Galactose-dependent reversible interaction of Gal3p with Gal80p in the induction pathway of Gal4p-activated genes of Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (1997) 1.65
Regulated expression of endonuclease EcoRI in Saccharomyces cerevisiae: nuclear entry and biological consequences. Proc Natl Acad Sci U S A (1985) 1.65
Functional domains of the yeast regulatory protein GAL4. Proc Natl Acad Sci U S A (1986) 1.64
Upstream activation sequence-dependent alteration of chromatin structure and transcription activation of the yeast GAL1-GAL10 genes. Mol Cell Biol (1989) 1.61
Analysis of constitutive and noninducible mutations of the PUT3 transcriptional activator. Mol Cell Biol (1991) 1.60
Evidence for Gal3p's cytoplasmic location and Gal80p's dual cytoplasmic-nuclear location implicates new mechanisms for controlling Gal4p activity in Saccharomyces cerevisiae. Mol Cell Biol (2000) 1.51
Analysis of the galactose signal transduction pathway in Saccharomyces cerevisiae: interaction between Gal3p and Gal80p. Mol Cell Biol (1996) 1.51
The relationship of regulatory proteins and DNase I hypersensitive sites in the yeast GAL1-10 genes. Nucleic Acids Res (1985) 1.50
GAL4 protein: purification, association with GAL80 protein, and conserved domain structure. Mol Cell Biol (1990) 1.50
Two regulators of Ste12p inhibit pheromone-responsive transcription by separate mechanisms. Mol Cell Biol (2000) 1.49
Cloning and analysis of the positively acting regulatory gene amdR from Aspergillus nidulans. Mol Cell Biol (1988) 1.49
Regulation of expression and activity of the yeast transcription factor ADR1. Mol Cell Biol (1988) 1.47
Molecular characterization of Saccharomyces cerevisiae TFIID. Mol Cell Biol (2002) 1.46
Identification of two proteins encoded by the Saccharomyces cerevisiae GAL4 gene. Mol Cell Biol (1984) 1.45
SWI-SNF complex participation in transcriptional activation at a step subsequent to activator binding. Mol Cell Biol (1998) 1.40
Gene activation by interaction of an inhibitor with a cytoplasmic signaling protein. Proc Natl Acad Sci U S A (2002) 1.39
Novel Gal3 proteins showing altered Gal80p binding cause constitutive transcription of Gal4p-activated genes in Saccharomyces cerevisiae. Mol Cell Biol (1997) 1.37
A yeast expression system for human galactose-1-phosphate uridylyltransferase. Proc Natl Acad Sci U S A (1993) 1.35
No strict alignment is required between a transcriptional activator binding site and the "TATA box" of a yeast gene. Proc Natl Acad Sci U S A (1988) 1.35
Suppressor gene analysis reveals an essential role for sphingolipids in transport of glycosylphosphatidylinositol-anchored proteins in Saccharomyces cerevisiae. J Bacteriol (1997) 1.35
DNase I-hypersensitive sites in the galactose gene cluster of Saccharomyces cerevisiae. Mol Cell Biol (1985) 1.33
Transcription of the ADH2 gene in Saccharomyces cerevisiae is limited by positive factors that bind competitively to its intact promoter region on multicopy plasmids. Mol Cell Biol (1987) 1.33
GAL4 of Saccharomyces cerevisiae activates the lactose-galactose regulon of Kluyveromyces lactis and creates a new phenotype: glucose repression of the regulon. Mol Cell Biol (1987) 1.33
Prenylated isoforms of yeast casein kinase I, including the novel Yck3p, suppress the gcs1 blockage of cell proliferation from stationary phase. Mol Cell Biol (1996) 1.32
The Gal3p-Gal80p-Gal4p transcription switch of yeast: Gal3p destabilizes the Gal80p-Gal4p complex in response to galactose and ATP. Mol Cell Biol (1999) 1.30
Isolation of mutant Saccharomyces cerevisiae strains that survive without sphingolipids. Mol Cell Biol (1990) 1.29
Multiple mechanisms mediate glucose repression of the yeast GAL1 gene. Proc Natl Acad Sci U S A (1992) 1.29
Complete sequence of a eukaryotic regulatory gene. EMBO J (1983) 1.28
Genetic and biochemical characterization of the galactose gene cluster in Kluyveromyces lactis. J Bacteriol (1984) 1.28
Phosphorylated forms of GAL4 are correlated with ability to activate transcription. Mol Cell Biol (1990) 1.26
Characterization of enzymatic synthesis of sphingolipid long-chain bases in Saccharomyces cerevisiae: mutant strains exhibiting long-chain-base auxotrophy are deficient in serine palmitoyltransferase activity. J Bacteriol (1992) 1.21
A member of a novel family of yeast 'zn-finger' proteins mediates the transition from stationary phase to cell proliferation. EMBO J (1994) 1.20
Characterization of Mmp37p, a Saccharomyces cerevisiae mitochondrial matrix protein with a role in mitochondrial protein import. Mol Biol Cell (2006) 1.20
Functional domains of a negative regulatory protein, GAL80, of Saccharomyces cerevisiae. Mol Cell Biol (1989) 1.19
Interaction between transcriptional activator protein LAC9 and negative regulatory protein GAL80. Mol Cell Biol (1989) 1.19
GAL4 mutations that separate the transcriptional activation and GAL80-interactive functions of the yeast GAL4 protein. Genetics (1990) 1.19
Production of the CYS3 regulator, a bZIP DNA-binding protein, is sufficient to induce sulfur gene expression in Neurospora crassa. Mol Cell Biol (1992) 1.18
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Dual influence of the yeast Cat1p (Snf1p) protein kinase on carbon source-dependent transcriptional activation of gluconeogenic genes by the regulatory gene CAT8. Nucleic Acids Res (1996) 1.18
Identification of upstream activator sequences that regulate induction of the beta-galactosidase gene in Kluyveromyces lactis. Mol Cell Biol (1987) 1.18
Saccharomyces cerevisiae PHO5 promoter region: location and function of the upstream activation site. Mol Cell Biol (1986) 1.18
A yeast mutant conditionally defective only for reentry into the mitotic cell cycle from stationary phase. Proc Natl Acad Sci U S A (1987) 1.17
Expression of the gene for ornithine decarboxylase of Saccharomyces cerevisiae in Escherichia coli. Mol Cell Biol (1985) 1.15
The mechanism of inducer formation in gal3 mutants of the yeast galactose system is independent of normal galactose metabolism and mitochondrial respiratory function. Genetics (1991) 1.15
Myocyte nuclear factor, a novel winged-helix transcription factor under both developmental and neural regulation in striated myocytes. Mol Cell Biol (1994) 1.15
Autogenous regulation of the positive regulatory qa-1F gene in Neurospora crassa. Mol Cell Biol (1985) 1.13
A gene product needed for induction of allantoin system genes in Saccharomyces cerevisiae but not for their transcriptional activation. Mol Cell Biol (1989) 1.13
Analysis of a eukaryotic beta-galactosidase gene: the N-terminal end of the yeast Kluyveromyces lactis protein shows homology to the Escherichia coli lacZ gene product. Nucleic Acids Res (1984) 1.12
Construction of strains of Saccharomyces cerevisiae that grow on lactose. Proc Natl Acad Sci U S A (1985) 1.12
The Saccharomyces cerevisiae Cdc68 transcription activator is antagonized by San1, a protein implicated in transcriptional silencing. Mol Cell Biol (1993) 1.11
Gal80-Gal80 interaction on adjacent Gal4p binding sites is required for complete GAL gene repression. EMBO J (2001) 1.10
The activation domain of GAL4 protein mediates cooperative promoter binding with general transcription factors in vivo. Proc Natl Acad Sci U S A (1995) 1.08
Functional coupling of a mammalian somatostatin receptor to the yeast pheromone response pathway. Mol Cell Biol (1995) 1.08
Glucose repression of lactose/galactose metabolism in Kluyveromyces lactis is determined by the concentration of the transcriptional activator LAC9 (K1GAL4) [corrected]. Nucleic Acids Res (1993) 1.08
Isolation of constitutive mutations affecting the proline utilization pathway in Saccharomyces cerevisiae and molecular analysis of the PUT3 transcriptional activator. Mol Cell Biol (1989) 1.07
Expression of the Saccharomyces cerevisiae GAL7 gene on autonomous plasmids. Mol Cell Biol (1984) 1.06
GAL11 (SPT13), a transcriptional regulator of diverse yeast genes, affects the phosphorylation state of GAL4, a highly specific transcriptional activator. Mol Cell Biol (1991) 1.05
Transcription of a yeast phosphoglucomutase isozyme gene is galactose inducible and glucose repressible. Mol Cell Biol (1990) 1.05
Gal80 proteins of Kluyveromyces lactis and Saccharomyces cerevisiae are highly conserved but contribute differently to glucose repression of the galactose regulon. Mol Cell Biol (1993) 1.02
Upf1 and Upf2 proteins mediate normal yeast mRNA degradation when translation initiation is limited. Nucleic Acids Res (1998) 1.02
Regulatory gene INO4 of yeast phospholipid biosynthesis is positively autoregulated and functions as a transactivator of fatty acid synthase genes FAS1 and FAS2 from Saccharomyces cerevisiae. Nucleic Acids Res (1992) 1.01
A single GAL4 dimer can maximally activate transcription under physiological conditions. Proc Natl Acad Sci U S A (1995) 0.98
Yeast prt1 mutations alter heat-shock gene expression through transcript fragmentation. EMBO J (1993) 0.97
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