Published in Nat Rev Genet on October 01, 2000
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Human ES cell-derived neural rosettes reveal a functionally distinct early neural stem cell stage. Genes Dev (2008) 5.34
Conversion of mouse and human fibroblasts into functional spinal motor neurons. Cell Stem Cell (2011) 4.65
The mechanisms of Hedgehog signalling and its roles in development and disease. Nat Rev Mol Cell Biol (2013) 3.84
The Sox9 transcription factor determines glial fate choice in the developing spinal cord. Genes Dev (2003) 3.46
Directed differentiation of dopaminergic neuronal subtypes from human embryonic stem cells. Stem Cells (2005) 3.38
Dorsoventral patterning in hemichordates: insights into early chordate evolution. PLoS Biol (2006) 3.30
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THM1 negatively modulates mouse sonic hedgehog signal transduction and affects retrograde intraflagellar transport in cilia. Nat Genet (2008) 3.19
Tangential neuronal migration controls axon guidance: a role for neuregulin-1 in thalamocortical axon navigation. Cell (2006) 3.12
Fezl regulates the differentiation and axon targeting of layer 5 subcortical projection neurons in cerebral cortex. Proc Natl Acad Sci U S A (2005) 2.81
A cluster of cholinergic premotor interneurons modulates mouse locomotor activity. Neuron (2009) 2.75
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Directed differentiation of ventral spinal progenitors and motor neurons from human embryonic stem cells by small molecules. Stem Cells (2008) 2.54
Gene regulatory logic for reading the Sonic Hedgehog signaling gradient in the vertebrate neural tube. Cell (2012) 2.54
Genome-wide analyses identify transcription factors required for proper morphogenesis of Drosophila sensory neuron dendrites. Genes Dev (2006) 2.49
Convergent extension, planar-cell-polarity signalling and initiation of mouse neural tube closure. Development (2007) 2.45
Coordinated actions of the forkhead protein Foxp1 and Hox proteins in the columnar organization of spinal motor neurons. Neuron (2008) 2.44
Gli2 trafficking links Hedgehog-dependent activation of Smoothened in the primary cilium to transcriptional activation in the nucleus. Proc Natl Acad Sci U S A (2009) 2.43
Olig2 and Ngn2 function in opposition to modulate gene expression in motor neuron progenitor cells. Genes Dev (2005) 2.40
Measured motion: searching for simplicity in spinal locomotor networks. Curr Opin Neurobiol (2009) 2.40
V3 spinal neurons establish a robust and balanced locomotor rhythm during walking. Neuron (2008) 2.35
Hindbrain interneurons and axon guidance signaling critical for breathing. Nat Neurosci (2010) 2.34
The requirement of Nkx2-1 in the temporal specification of cortical interneuron subtypes. Neuron (2008) 2.33
Astrocytes and disease: a neurodevelopmental perspective. Genes Dev (2012) 2.28
SOX5 postmitotically regulates migration, postmigratory differentiation, and projections of subplate and deep-layer neocortical neurons. Proc Natl Acad Sci U S A (2008) 2.26
Regulation of motor neuron specification by phosphorylation of neurogenin 2. Neuron (2008) 2.20
Specification of neuronal identities by feedforward combinatorial coding. PLoS Biol (2007) 2.19
Computational prediction of neural progenitor cell fates. Nat Methods (2010) 2.15
Dorsal-ventral patterning of the spinal cord requires Gli3 transcriptional repressor activity. Genes Dev (2002) 2.10
A direct requirement for Hedgehog signaling for normal specification of all ventral progenitor domains in the presumptive mammalian spinal cord. Genes Dev (2002) 2.09
The Fezf2-Ctip2 genetic pathway regulates the fate choice of subcortical projection neurons in the developing cerebral cortex. Proc Natl Acad Sci U S A (2008) 2.07
The spatial and temporal origin of chandelier cells in mouse neocortex. Science (2012) 2.07
Efficient derivation of functional floor plate tissue from human embryonic stem cells. Cell Stem Cell (2010) 2.02
The developmental integration of cortical interneurons into a functional network. Curr Top Dev Biol (2009) 2.01
Wnt signaling plays an essential role in neuronal specification of the dorsal spinal cord. Genes Dev (2002) 2.01
Arsenic antagonizes the Hedgehog pathway by preventing ciliary accumulation and reducing stability of the Gli2 transcriptional effector. Proc Natl Acad Sci U S A (2010) 2.00
LIM homeobox gene-dependent expression of biogenic amine receptors in restricted regions of the C. elegans nervous system. Dev Biol (2003) 1.98
Decision by division: making cortical maps. Trends Neurosci (2009) 1.97
Generation of neural crest-derived peripheral neurons and floor plate cells from mouse and primate embryonic stem cells. Proc Natl Acad Sci U S A (2003) 1.93
A mutation in the Gsk3-binding domain of zebrafish Masterblind/Axin1 leads to a fate transformation of telencephalon and eyes to diencephalon. Genes Dev (2001) 1.90
Exploring the regulation of human neural precursor cell differentiation using arrays of signaling microenvironments. Mol Syst Biol (2006) 1.90
Astrocyte-encoded positional cues maintain sensorimotor circuit integrity. Nature (2014) 1.88
The Hedgehog-binding proteins Gas1 and Cdo cooperate to positively regulate Shh signaling during mouse development. Genes Dev (2007) 1.87
Rapid and efficient generation of functional motor neurons from human pluripotent stem cells using gene delivered transcription factor codes. Mol Ther (2011) 1.85
Rapid and robust generation of functional oligodendrocyte progenitor cells from epiblast stem cells. Nat Methods (2011) 1.85
Phosphorylation state of Olig2 regulates proliferation of neural progenitors. Neuron (2011) 1.83
Different timings of Dicer deletion affect neurogenesis and gliogenesis in the developing mouse central nervous system. Dev Dyn (2009) 1.83
Postmitotic Nkx2-1 controls the migration of telencephalic interneurons by direct repression of guidance receptors. Neuron (2008) 1.81
Identification of positionally distinct astrocyte subtypes whose identities are specified by a homeodomain code. Cell (2008) 1.79
Glial scar borders are formed by newly proliferated, elongated astrocytes that interact to corral inflammatory and fibrotic cells via STAT3-dependent mechanisms after spinal cord injury. J Neurosci (2013) 1.79
An early role for WNT signaling in specifying neural patterns of Cdx and Hox gene expression and motor neuron subtype identity. PLoS Biol (2006) 1.76
A spatial bias for the origins of interneuron subgroups within the medial ganglionic eminence. Dev Biol (2007) 1.76
Disruption at the PTCHD1 Locus on Xp22.11 in Autism spectrum disorder and intellectual disability. Sci Transl Med (2010) 1.75
The antioxidant enzyme Prdx1 controls neuronal differentiation by thiol-redox-dependent activation of GDE2. Cell (2009) 1.75
Persistent sonic hedgehog signaling in adult brain determines neural stem cell positional identity. Neuron (2011) 1.73
Phosphorylation regulates OLIG2 cofactor choice and the motor neuron-oligodendrocyte fate switch. Neuron (2011) 1.72
Specification of the mammalian cochlea is dependent on Sonic hedgehog. Genes Dev (2002) 1.71
Decoding the rules of recruitment of excitatory interneurons in the adult zebrafish locomotor network. Proc Natl Acad Sci U S A (2012) 1.70
Gli proteins and the control of spinal-cord patterning. EMBO Rep (2003) 1.68
A gradient of Gli activity mediates graded Sonic Hedgehog signaling in the neural tube. Genes Dev (2005) 1.68
The bHLH factor Olig3 coordinates the specification of dorsal neurons in the spinal cord. Genes Dev (2005) 1.66
Activation of groups of excitatory neurons in the mammalian spinal cord or hindbrain evokes locomotion. Nat Neurosci (2010) 1.63
Coordinated temporal and spatial control of motor neuron and serotonergic neuron generation from a common pool of CNS progenitors. Genes Dev (2003) 1.60
Mediator modulates Gli3-dependent Sonic hedgehog signaling. Mol Cell Biol (2006) 1.58
Dynamic assignment and maintenance of positional identity in the ventral neural tube by the morphogen sonic hedgehog. PLoS Biol (2010) 1.58
Efficient production of mesencephalic dopamine neurons by Lmx1a expression in embryonic stem cells. Proc Natl Acad Sci U S A (2009) 1.57
Pax6 and engrailed 1 regulate two distinct aspects of renshaw cell development. J Neurosci (2004) 1.56
SnapShot: spinal cord development. Cell (2011) 1.56
Postnatal phenotype and localization of spinal cord V1 derived interneurons. J Comp Neurol (2005) 1.55
A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Dev Cell (2009) 1.53
Notch and MAML signaling drives Scl-dependent interneuron diversity in the spinal cord. Neuron (2007) 1.52
Leveling Waddington: the emergence of direct programming and the loss of cell fate hierarchies. Nat Rev Mol Cell Biol (2013) 1.52
Gene expression in cortical interneuron precursors is prescient of their mature function. Cereb Cortex (2008) 1.51
Distinct Sonic Hedgehog signaling dynamics specify floor plate and ventral neuronal progenitors in the vertebrate neural tube. Genes Dev (2010) 1.51
Specification of region-specific neurons including forebrain glutamatergic neurons from human induced pluripotent stem cells. PLoS One (2010) 1.48
Temporal fate specification and neural progenitor competence during development. Nat Rev Neurosci (2013) 1.48
Phosphorylation of Gli2 by protein kinase A is required for Gli2 processing and degradation and the Sonic Hedgehog-regulated mouse development. Dev Biol (2008) 1.48
Radial glial progenitors repair the zebrafish spinal cord following transection. Exp Neurol (2014) 1.48
Regulatory pathways linking progenitor patterning, cell fates and neurogenesis in the ventral neural tube. Philos Trans R Soc Lond B Biol Sci (2008) 1.48
Genetic and biochemical definition of the Hedgehog receptor. Genes Dev (2010) 1.47
Gene delivery into mouse retinal ganglion cells by in utero electroporation. BMC Dev Biol (2007) 1.47
MicroRNA-9 reveals regional diversity of neural progenitors along the anterior-posterior axis. Dev Cell (2011) 1.47
Physiological Notch signaling promotes gliogenesis in the developing peripheral and central nervous systems. Development (2007) 1.47
Anatomy and function of cholinergic C bouton inputs to motor neurons. J Anat (2013) 1.47
Nuclear pore composition regulates neural stem/progenitor cell differentiation in the mouse embryo. Dev Cell (2008) 1.46
Molecular mechanisms of synaptic specificity in developing neural circuits. Neuron (2010) 1.46
Cis-regulatory control of corticospinal system development and evolution. Nature (2012) 1.43
Functional diversity of ESC-derived motor neuron subtypes revealed through intraspinal transplantation. Cell Stem Cell (2010) 1.42
Establishing and interpreting graded Sonic Hedgehog signaling during vertebrate neural tube patterning: the role of negative feedback. Cold Spring Harb Perspect Biol (2009) 1.41
Scaling Pattern to Variations in Size during Development of the Vertebrate Neural Tube. Dev Cell (2016) 1.41
Defining the excitatory neurons that drive the locomotor rhythm in a simple vertebrate: insights into the origin of reticulospinal control. J Physiol (2009) 1.41
A regulatory network to segregate the identity of neuronal subtypes. Dev Cell (2008) 1.41
Global control of motor neuron topography mediated by the repressive actions of a single hox gene. Neuron (2010) 1.41
The continuing case for the Renshaw cell. J Physiol (2007) 1.41
In vitro generation of neuromesodermal progenitors reveals distinct roles for wnt signalling in the specification of spinal cord and paraxial mesoderm identity. PLoS Biol (2014) 1.39
Loss of the serine/threonine kinase fused results in postnatal growth defects and lethality due to progressive hydrocephalus. Mol Cell Biol (2005) 1.39
Homeostatic signaling and the stabilization of neural function. Neuron (2013) 1.38
Expression of Terminal Effector Genes in Mammalian Neurons Is Maintained by a Dynamic Relay of Transient Enhancers. Neuron (2016) 1.37