Published in Mol Cell Biol on April 01, 2001
Repression domains of class II ERF transcriptional repressors share an essential motif for active repression. Plant Cell (2001) 4.19
Snail mediates E-cadherin repression by the recruitment of the Sin3A/histone deacetylase 1 (HDAC1)/HDAC2 complex. Mol Cell Biol (2004) 4.15
Sin3: a flexible regulator of global gene expression and genome stability. Curr Genet (2004) 2.60
A rice WRKY gene encodes a transcriptional repressor of the gibberellin signaling pathway in aleurone cells. Plant Physiol (2004) 1.74
Epigenetics and bacterial infections. Cold Spring Harb Perspect Med (2012) 1.56
Dynamic acetylation of all lysine 4-methylated histone H3 in the mouse nucleus: analysis at c-fos and c-jun. PLoS Biol (2005) 1.53
Mechanisms of specificity in neuronal activity-regulated gene transcription. Prog Neurobiol (2011) 1.49
MAP kinase phosphorylation-dependent activation of Elk-1 leads to activation of the co-activator p300. EMBO J (2003) 1.47
Repression of E2F1-mediated transcription by the ErbB3 binding protein Ebp1 involves histone deacetylases. Nucleic Acids Res (2003) 1.46
Functional cross-antagonism between transcription factors FLI-1 and EKLF. Mol Cell Biol (2003) 1.42
PIASx acts as an Elk-1 coactivator by facilitating derepression. EMBO J (2005) 1.25
Cellular and molecular mechanisms of synovial joint and articular cartilage formation. Ann N Y Acad Sci (2006) 1.23
Transcription factor ERG and joint and articular cartilage formation during mouse limb and spine skeletogenesis. Dev Biol (2007) 1.21
Mitogen-induced recruitment of ERK and MSK to SRE promoter complexes by ternary complex factor Elk-1. Nucleic Acids Res (2008) 1.18
The corepressor mSin3A regulates phosphorylation-induced activation, intranuclear location, and stability of AML1. Mol Cell Biol (2004) 1.16
Elk-1 a transcription factor with multiple facets in the brain. Front Neurosci (2011) 1.15
The ETS domain transcription factor Elk-1 contains a novel class of repression domain. Mol Cell Biol (2002) 1.12
Hypoxia-mediated downregulation of miRNA biogenesis promotes tumour progression. Nat Commun (2014) 1.10
Activation and repression of cellular immediate early genes by serum response factor cofactors. J Biol Chem (2010) 1.08
Long-lasting behavioral responses to stress involve a direct interaction of glucocorticoid receptors with ERK1/2-MSK1-Elk-1 signaling. Proc Natl Acad Sci U S A (2011) 1.08
Molecular mechanisms of ETS transcription factor-mediated tumorigenesis. Crit Rev Biochem Mol Biol (2013) 1.08
ERF nuclear shuttling, a continuous monitor of Erk activity that links it to cell cycle progression. Mol Cell Biol (2004) 1.07
Identification and characterization of SAP25, a novel component of the mSin3 corepressor complex. Mol Cell Biol (2006) 1.02
CCN5, a novel transcriptional repressor of the transforming growth factor β signaling pathway. Mol Cell Biol (2011) 1.02
Mice deficient for the ets transcription factor elk-1 show normal immune responses and mildly impaired neuronal gene activation. Mol Cell Biol (2004) 1.01
Rev7/MAD2B links c-Jun N-terminal protein kinase pathway signaling to activation of the transcription factor Elk-1. Mol Cell Biol (2007) 1.00
Functional interactions between the Forkhead transcription factor FOXK1 and the MADS-box protein SRF. Nucleic Acids Res (2007) 0.99
Lysophosphatidic acid protects cancer cells from histone deacetylase (HDAC) inhibitor-induced apoptosis through activation of HDAC. J Biol Chem (2008) 0.95
17beta-Estradiol inhibits matrix metalloproteinase-2 transcription via MAP kinase in fibroblasts. Cardiovasc Res (2009) 0.94
Adhesion regulates MAP kinase/ternary complex factor exchange to control a proliferative transcriptional switch. Curr Biol (2012) 0.93
Regulation of TCF ETS-domain transcription factors by helix-loop-helix motifs. Nucleic Acids Res (2003) 0.91
Unlocking repression of the human luteinizing hormone receptor gene by trichostatin A-induced cell-specific phosphatase release. J Biol Chem (2008) 0.89
Functional analysis of the Mad1-mSin3A repressor-corepressor interaction reveals determinants of specificity, affinity, and transcriptional response. Mol Cell Biol (2004) 0.87
Site-specific association with host and viral chromatin by Kaposi's sarcoma-associated herpesvirus LANA and its reversal during lytic reactivation. J Virol (2014) 0.86
Regulation of transcription of the RNA splicing factor hSlu7 by Elk-1 and Sp1 affects alternative splicing. RNA (2007) 0.82
ERK-associated changes of AP-1 proteins during fear extinction. Mol Cell Neurosci (2011) 0.81
EGF activates TTP expression by activation of ELK-1 and EGR-1 transcription factors. BMC Mol Biol (2012) 0.80
Katanin-p80 gene promoter characterization and regulation via Elk1. PLoS One (2013) 0.78
Class I histone deacetylase-mediated repression of the proximal promoter of the activity-regulated cytoskeleton-associated protein gene regulates its response to brain-derived neurotrophic factor. J Biol Chem (2015) 0.78
LPS-Induced G-CSF Expression in Macrophages Is Mediated by ERK2, but Not ERK1. PLoS One (2015) 0.77
Inhibition of polyomavirus ori-dependent DNA replication by mSin3B. J Virol (2002) 0.77
The Mediator Kinase Module Restrains Epidermal Growth Factor Receptor Signaling and Represses Vulval Cell Fate Specification in Caenorhabditis elegans. Genetics (2015) 0.76
Insights into Lysine Deacetylation of Natively Folded Substrate Proteins by Sirtuins. J Biol Chem (2016) 0.76
The Proto-oncogene Transcription Factor Ets1 Regulates Neural Crest Development through Histone Deacetylase 1 to Mediate Output of Bone Morphogenetic Protein Signaling. J Biol Chem (2015) 0.76
The roles of EGF and Wnt signaling during patterning of the C. elegans Bgamma/delta Equivalence Group. BMC Dev Biol (2009) 0.75
The Role of Early Growth Response 1 (EGR1) in Brain Plasticity and Neuropsychiatric Disorders. Front Behav Neurosci (2017) 0.75
The Amino-terminal Domain of the Androgen Receptor Co-opts Extracellular Signal-regulated Kinase (ERK) Docking Sites in ELK1 Protein to Induce Sustained Gene Activation That Supports Prostate Cancer Cell Growth. J Biol Chem (2016) 0.75
The Rho family GTPases RhoA, Rac1, and CDC42Hs regulate transcriptional activation by SRF. Cell (1995) 8.20
Histone deacetylases associated with the mSin3 corepressor mediate mad transcriptional repression. Cell (1997) 7.64
The SRF accessory protein Elk-1 contains a growth factor-regulated transcriptional activation domain. Cell (1993) 7.37
Regulation of transcription by MAP kinase cascades. Curr Opin Cell Biol (1996) 5.99
What's up and down with histone deacetylation and transcription? Cell (1997) 5.99
Synergistic coupling of histone H3 phosphorylation and acetylation in response to epidermal growth factor stimulation. Mol Cell (2000) 5.79
Transcriptional regulation by extracellular signals: mechanisms and specificity. Cell (1995) 5.44
Cdk phosphorylation triggers sequential intramolecular interactions that progressively block Rb functions as cells move through G1. Cell (1999) 4.94
Coactivator and corepressor complexes in nuclear receptor function. Curr Opin Genet Dev (1999) 4.92
Ternary complex factors: growth factor regulated transcriptional activators. Curr Opin Genet Dev (1994) 4.46
ERK phosphorylation potentiates Elk-1-mediated ternary complex formation and transactivation. EMBO J (1995) 3.86
Multiple docking sites on substrate proteins form a modular system that mediates recognition by ERK MAP kinase. Genes Dev (1999) 3.79
Transcriptional repression by wild-type p53 utilizes histone deacetylases, mediated by interaction with mSin3a. Genes Dev (1999) 3.41
Mammalian Srb/Mediator complex is targeted by adenovirus E1A protein. Nature (1999) 3.24
Histone acetylases and deacetylases in cell proliferation. Curr Opin Genet Dev (1999) 3.22
Repression by Ikaros and Aiolos is mediated through histone deacetylase complexes. EMBO J (1999) 3.11
A Smad transcriptional corepressor. Cell (1999) 3.07
Signal transduction within the nucleus by mitogen-activated protein kinase. J Biol Chem (1992) 2.93
Comparative analysis of the ternary complex factors Elk-1, SAP-1a and SAP-2 (ERP/NET). EMBO J (1995) 2.72
Repression versus activation in the control of gene transcription. Trends Biochem Sci (1994) 2.65
The serum response element. Trends Biochem Sci (1992) 2.61
Differential targeting of MAP kinases to the ETS-domain transcription factor Elk-1. EMBO J (1998) 2.54
Histone deacetylases: transcriptional repression with SINers and NuRDs. Trends Cell Biol (1999) 2.46
The Elk-1 ETS-domain transcription factor contains a mitogen-activated protein kinase targeting motif. Mol Cell Biol (1998) 2.44
Activation of SRF-regulated chromosomal templates by Rho-family GTPases requires a signal that also induces H4 hyperacetylation. Cell (1998) 2.29
The transcription factors Elk-1 and serum response factor interact by direct protein-protein contacts mediated by a short region of Elk-1. Mol Cell Biol (1994) 2.22
Transcriptional repression in eukaryotes. Annu Rev Cell Biol (1993) 2.17
Net, a new ets transcription factor that is activated by Ras. Genes Dev (1994) 2.12
Reporter constructs with low background activity utilizing the cat gene. Gene (1992) 2.02
Net, a negative Ras-switchable TCF, contains a second inhibition domain, the CID, that mediates repression through interactions with CtBP and de-acetylation. EMBO J (1999) 1.76
Two pathways for serum regulation of the c-fos serum response element require specific sequence elements and a minimal domain of serum response factor. Mol Cell Biol (1994) 1.73
Retinoblastoma protein meets chromatin. Trends Biochem Sci (1999) 1.72
MAP kinase-dependent transcriptional coactivation by Elk-1 and its cofactor CBP. Biochem Biophys Res Commun (1996) 1.65
SAP1a is a nuclear target of signaling cascades involving ERKs. Oncogene (1995) 1.65
Histone deacetylases: complex transducers of nuclear signals. Semin Cell Dev Biol (1999) 1.57
Both TEL and AML-1 contribute repression domains to the t(12;21) fusion protein. Mol Cell Biol (1999) 1.53
Functional dissection of the transcription factor Elk-1. Oncogene (1994) 1.42
TEL is a sequence-specific transcriptional repressor. J Biol Chem (1999) 1.39
Id helix-loop-helix proteins inhibit nucleoprotein complex formation by the TCF ETS-domain transcription factors. EMBO J (1999) 1.37
The mechanism of phosphorylation-inducible activation of the ETS-domain transcription factor Elk-1. EMBO J (1999) 1.36
The ETS-domain transcription factors Elk-1 and SAP-1 exhibit differential DNA binding specificities. Nucleic Acids Res (1995) 1.31
Characterization of the Elk-1 ETS DNA-binding domain. J Biol Chem (1995) 1.24
A 13-amino acid amphipathic alpha-helix is required for the functional interaction between the transcriptional repressor Mad1 and mSin3A. J Biol Chem (1999) 1.22
Net (ERP/SAP2) one of the Ras-inducible TCFs, has a novel inhibitory domain with resemblance to the helix-loop-helix motif. EMBO J (1996) 1.22
Molecular characterization of the zebrafish PEA3 ETS-domain transcription factor. Oncogene (1998) 1.11
Unusual c-fos induction upon chromaffin PC12 differentiation by sodium butyrate: loss of fos autoregulatory function. Nucleic Acids Res (1990) 0.91
Net-b, a Ras-insensitive factor that forms ternary complexes with serum response factor on the serum response element of the fos promoter. Mol Cell Biol (1997) 0.85
The mechanism of complex formation between Fli-1 and SRF transcription factors. Nucleic Acids Res (2000) 0.84
Selective recognition of methylated lysine 9 on histone H3 by the HP1 chromo domain. Nature (2001) 19.54
Analysis of the protein-coding content of the sequence of human cytomegalovirus strain AD169. Curr Top Microbiol Immunol (1990) 16.31
The CBP co-activator is a histone acetyltransferase. Nature (1997) 10.91
Retinoblastoma protein recruits histone deacetylase to repress transcription. Nature (1998) 8.75
Rb targets histone H3 methylation and HP1 to promoters. Nature (2001) 8.26
Germline regulatory element of Oct-4 specific for the totipotent cycle of embryonal cells. Development (1996) 7.00
Epstein-Barr virus BZLF1 trans-activator specifically binds to a consensus AP-1 site and is related to c-fos. EMBO J (1989) 5.93
Phosphorylation of transcription factor p62TCF by MAP kinase stimulates ternary complex formation at c-fos promoter. Nature (1992) 5.69
HDAC4 deacetylase associates with and represses the MEF2 transcription factor. EMBO J (1999) 5.54
Integration of MAP kinase signal transduction pathways at the serum response element. Science (1995) 5.45
DNA methyltransferase Dnmt1 associates with histone deacetylase activity. Nat Genet (2000) 5.29
The TAF(II)250 subunit of TFIID has histone acetyltransferase activity. Cell (1996) 5.20
The MADS-box family of transcription factors. Eur J Biochem (1995) 4.54
Regulation of E2F1 activity by acetylation. EMBO J (2000) 4.18
Opposing effects of Ets and Id proteins on p16INK4a expression during cellular senescence. Nature (2001) 4.14
Identification of the human cytomegalovirus glycoprotein B gene and induction of neutralizing antibodies via its expression in recombinant vaccinia virus. EMBO J (1986) 3.89
Transcriptional activation functions in BRCA2. Nature (1997) 3.86
Nuclear receptor corepressors partner with class II histone deacetylases in a Sin3-independent repression pathway. Genes Dev (2000) 3.38
Sequence and transcription analysis of the human cytomegalovirus DNA polymerase gene. J Virol (1987) 3.36
Dnmt3a binds deacetylases and is recruited by a sequence-specific repressor to silence transcription. EMBO J (2001) 3.36
Stimulation of E2F1/DP1 transcriptional activity by MDM2 oncoprotein. Nature (1995) 3.32
CBP-induced stimulation of c-Fos activity is abrogated by E1A. EMBO J (1995) 3.22
Repression of RNA polymerase III transcription by the retinoblastoma protein. Nature (1996) 3.04
The activation domain of transcription factor PU.1 binds the retinoblastoma (RB) protein and the transcription factor TFIID in vitro: RB shows sequence similarity to TFIID and TFIIB. Proc Natl Acad Sci U S A (1993) 2.90
Mutations truncating the EP300 acetylase in human cancers. Nat Genet (2000) 2.84
MEF-2 function is modified by a novel co-repressor, MITR. EMBO J (1999) 2.71
Stimulation of c-Jun activity by CBP: c-Jun residues Ser63/73 are required for CBP induced stimulation in vivo and CBP binding in vitro. Oncogene (1995) 2.64
Role of p38 and JNK mitogen-activated protein kinases in the activation of ternary complex factors. Mol Cell Biol (1997) 2.58
Differential targeting of MAP kinases to the ETS-domain transcription factor Elk-1. EMBO J (1998) 2.54
RB and hbrm cooperate to repress the activation functions of E2F1. Proc Natl Acad Sci U S A (1997) 2.53
The acetyltransferase activity of CBP stimulates transcription. EMBO J (1998) 2.45
The Elk-1 ETS-domain transcription factor contains a mitogen-activated protein kinase targeting motif. Mol Cell Biol (1998) 2.44
Targeting of p38 mitogen-activated protein kinases to MEF2 transcription factors. Mol Cell Biol (1999) 2.36
The co-repressor mSin3A is a functional component of the REST-CoREST repressor complex. J Biol Chem (2000) 2.28
Functional interaction between the HCMV IE2 transactivator and the retinoblastoma protein. EMBO J (1994) 2.25
The E7 oncoprotein associates with Mi2 and histone deacetylase activity to promote cell growth. EMBO J (1999) 2.23
The transcription factors Elk-1 and serum response factor interact by direct protein-protein contacts mediated by a short region of Elk-1. Mol Cell Biol (1994) 2.22
The retinoblastoma protein binds E2F residues required for activation in vivo and TBP binding in vitro. Nucleic Acids Res (1993) 2.17
Insights into early vasculogenesis revealed by expression of the ETS-domain transcription factor Fli-1 in wild-type and mutant zebrafish embryos. Mech Dev (2000) 2.13
Map position and nucleotide sequence of the gene for the large structural phosphoprotein of human cytomegalovirus. J Virol (1987) 2.11
Direct and indirect effects of amino acids on hepatic glucose metabolism in humans. Diabetologia (2003) 2.02
Physical and functional association of SU(VAR)3-9 and HDAC1 in Drosophila. EMBO Rep (2001) 1.97
The forkhead protein Fkh2 is a component of the yeast cell cycle transcription factor SFF. EMBO J (2000) 1.95
Epstein-Barr virus nuclear antigen 3C interacts with histone deacetylase to repress transcription. J Virol (1999) 1.92
Conserved motifs in Fos and Jun define a new class of activation domain. Genes Dev (1992) 1.90
E2F1-induced apoptosis requires DNA binding but not transactivation and is inhibited by the retinoblastoma protein through direct interaction. Genes Dev (1997) 1.85
E1A directly binds and regulates the P/CAF acetyltransferase. EMBO J (1998) 1.76
Transcriptional repression by the insulator protein CTCF involves histone deacetylases. Nucleic Acids Res (2000) 1.74
Retinoblastoma protein meets chromatin. Trends Biochem Sci (1999) 1.72
In vitro DNA binding activity of Fos/Jun and BZLF1 but not C/EBP is affected by redox changes. Oncogene (1991) 1.63
An E2F-like repressor of transcription. Nature (1997) 1.59
Viral oncoproteins target the DNA methyltransferases. Oncogene (2006) 1.59
Acetylation of importin-alpha nuclear import factors by CBP/p300. Curr Biol (2000) 1.54
E2F1 and E1A(12S) have a homologous activation domain regulated by RB and CBP. Proc Natl Acad Sci U S A (1996) 1.52
Differential localization of HDAC4 orchestrates muscle differentiation. Nucleic Acids Res (2001) 1.49
The CBP co-activator stimulates E2F1/DP1 activity. Nucleic Acids Res (1996) 1.47
c-Fos-induced activation of a TATA-box-containing promoter involves direct contact with TATA-box-binding protein. Mol Cell Biol (1994) 1.42
The maize retinoblastoma protein homologue ZmRb-1 is regulated during leaf development and displays conserved interactions with G1/S regulators and plant cyclin D (CycD) proteins. Plant Mol Biol (1998) 1.42
Mechanistic analysis of RNA polymerase III regulation by the retinoblastoma protein. EMBO J (1997) 1.41
The DNA sequence of the human cytomegalovirus genome. DNA Seq (1991) 1.38
Id helix-loop-helix proteins inhibit nucleoprotein complex formation by the TCF ETS-domain transcription factors. EMBO J (1999) 1.37
Large-scale rearrangement of homologous regions in the genomes of HCMV and EBV. Virology (1987) 1.36
The mechanism of phosphorylation-inducible activation of the ETS-domain transcription factor Elk-1. EMBO J (1999) 1.36
BRCA2 associates with acetyltransferase activity when bound to P/CAF. Oncogene (1998) 1.34
Properties of FNR proteins substituted at each of the five cysteine residues. Mol Microbiol (1993) 1.33
Determinants of DNA-binding specificity of ETS-domain transcription factors. Mol Cell Biol (1996) 1.32
Molecular characterization of the B-box protein-protein interaction motif of the ETS-domain transcription factor Elk-1. EMBO J (1997) 1.32
CBP/p300 as a co-factor for the Microphthalmia transcription factor. Oncogene (1997) 1.31
The ETS-domain transcription factors Elk-1 and SAP-1 exhibit differential DNA binding specificities. Nucleic Acids Res (1995) 1.31
Single-pair FRET microscopy reveals mononucleosome dynamics. J Fluoresc (2007) 1.29
The human cytomegalovirus 86-kilodalton major immediate-early protein interacts physically and functionally with histone acetyltransferase P/CAF. J Virol (2000) 1.28
Selective targeting of MAPKs to the ETS domain transcription factor SAP-1. J Biol Chem (2001) 1.26
The HMG-box transcription factor HBP1 is targeted by the pocket proteins and E1A. Oncogene (1997) 1.25
Characterization of the Elk-1 ETS DNA-binding domain. J Biol Chem (1995) 1.24
An inhibitor domain in c-Fos regulates activation domains containing the HOB1 motif. EMBO J (1995) 1.23
MCM3AP, a novel acetyltransferase that acetylates replication protein MCM3. EMBO Rep (2001) 1.23
DNA binding and dimerisation determinants of Antirrhinum majus MADS-box transcription factors. Nucleic Acids Res (1998) 1.20
Signalling pathways and the regulation of SUMO modification. Biochem Soc Trans (2007) 1.15
CBP/p300 integrates Raf/Rac-signaling pathways in the transcriptional induction of NF-ATc during T cell activation. Immunity (1999) 1.15
Solution structure of the MEF2A-DNA complex: structural basis for the modulation of DNA bending and specificity by MADS-box transcription factors. EMBO J (2000) 1.15
DNA binding by MADS-box transcription factors: a molecular mechanism for differential DNA bending. Mol Cell Biol (1997) 1.14
Evidence for a protein domain superfamily shared by the cyclins, TFIIB and RB/p107. Nucleic Acids Res (1994) 1.14
p300 is required for orderly G1/S transition in human cancer cells. Oncogene (2006) 1.13
Id helix-loop-helix proteins antagonize pax transcription factor activity by inhibiting DNA binding. Mol Cell Biol (2001) 1.13
Phylogeography of the human mitochondrial haplogroup L3e: a snapshot of African prehistory and Atlantic slave trade. Ann Hum Genet (2001) 1.12
Molecular characterization of the zebrafish PEA3 ETS-domain transcription factor. Oncogene (1998) 1.11
Characterization of an E1A-CBP interaction defines a novel transcriptional adapter motif (TRAM) in CBP/p300. J Virol (1999) 1.11
DNA binding by the ETS-domain transcription factor PEA3 is regulated by intramolecular and intermolecular protein.protein interactions. J Biol Chem (2001) 1.10
A C-terminal domain in FosB, absent in FosB/SF and Fra-1, which is able to interact with the TATA binding protein, is required for altered cell growth. EMBO J (1994) 1.08
Interaction of transcription factors with serum response factor. Identification of the Elk-1 binding surface. J Biol Chem (1998) 1.08
Quantitative ATP synthesis in human liver measured by localized 31P spectroscopy using the magnetization transfer experiment. NMR Biomed (2008) 1.07
Tramtrack69 interacts with the dMi-2 subunit of the Drosophila NuRD chromatin remodelling complex. EMBO Rep (2001) 1.07
Mutation analysis of CBP and PCAF reveals rare inactivating mutations in cancer cell lines but not in primary tumours. Br J Cancer (2002) 1.05
Nucleotide sequence of the transforming region of human cytomegalovirus. Mol Biol Med (1983) 1.04