Ratios of multijet Cross Sections in p p collisions at radical(s) = 1.8 TeV.

Initial sequencing and analysis of the human genome. Nature (2001) 212.86

Apparatus for Collecting and Measuring the Gases evolved during Fermentation. Biochem J (1911) 157.76

MEASUREMENT OF CARDIAC OUTPUT IN MAN USING THE TECHNIQUE OF CATHETERIZATION OF THE RIGHT AURICLE OR VENTRICLE. J Clin Invest (1945) 20.31

Gene expression analysis by massively parallel signature sequencing (MPSS) on microbead arrays. Nat Biotechnol (2000) 15.79

The genome sequence of Schizosaccharomyces pombe. Nature (2002) 14.26

Helicobacter pylori infection and gastric lymphoma. N Engl J Med (1994) 10.26

A Simple Method for the Silver Impregnation of Reticulum. Am J Pathol (1936) 9.76

Full-genome RNAi profiling of early embryogenesis in Caenorhabditis elegans. Nature (2005) 9.50

TLR4 mutations are associated with endotoxin hyporesponsiveness in humans. Nat Genet (2000) 8.79

Do u smoke after txt? Results of a randomised trial of smoking cessation using mobile phone text messaging. Tob Control (2005) 8.56

A critical appraisal of "chronic Lyme disease". N Engl J Med (2007) 7.84

Artesunate combinations for treatment of malaria: meta-analysis. Lancet (2004) 7.54

Caring for the critically ill patient. Current and projected workforce requirements for care of the critically ill and patients with pulmonary disease: can we meet the requirements of an aging population? JAMA (2000) 7.52

The DNA sequence and comparative analysis of human chromosome 20. Nature (2002) 7.40

LYVE-1, a new homologue of the CD44 glycoprotein, is a lymph-specific receptor for hyaluronan. J Cell Biol (1999) 7.27

Antivirals for influenza in healthy adults: systematic review. Lancet (2006) 7.20

Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53. Cell (1992) 7.06

Fas preassociation required for apoptosis signaling and dominant inhibition by pathogenic mutations. Science (2000) 6.98

Sequence and characteristics of IS900, an insertion element identified in a human Crohn's disease isolate of Mycobacterium paratuberculosis. Nucleic Acids Res (1989) 6.92

Alagille syndrome is caused by mutations in human Jagged1, which encodes a ligand for Notch1. Nat Genet (1997) 6.66

Prevalence of specific language impairment in kindergarten children. J Speech Lang Hear Res (1997) 6.37

Zymohexase: With an Addendum by E. C. Bate-Smith. Biochem J (1940) 6.34

Diffusion-weighted MR imaging of anisotropic water diffusion in cat central nervous system. Radiology (1990) 6.12

Characterization of circulating T cells specific for tumor-associated antigens in melanoma patients. Nat Med (1999) 6.09

Characterization of dystrophin in muscle-biopsy specimens from patients with Duchenne's or Becker's muscular dystrophy. N Engl J Med (1988) 5.84

Asthma. From bronchoconstriction to airways inflammation and remodeling. Am J Respir Crit Care Med (2000) 5.82

An immunohistochemical study of the pathology of fatal malaria. Evidence for widespread endothelial activation and a potential role for intercellular adhesion molecule-1 in cerebral sequestration. Am J Pathol (1994) 5.34

An integrated computational pipeline and database to support whole-genome sequence annotation. Genome Biol (2002) 5.24

Association of hormone-replacement therapy with various cardiovascular risk factors in postmenopausal women. The Atherosclerosis Risk in Communities Study Investigators. N Engl J Med (1993) 5.14

A testing time for doctors: counselling patients before an HIV test. BMJ (1991) 5.14

Magnetic resonance imaging of the entorhinal cortex and hippocampus in mild cognitive impairment and Alzheimer's disease. J Neurol Neurosurg Psychiatry (2001) 5.12

Prescribing trends in psychotropic medications: primary care, psychiatry, and other medical specialties. JAMA (1998) 5.09

Circadian rhythms in prokaryotes: luciferase as a reporter of circadian gene expression in cyanobacteria. Proc Natl Acad Sci U S A (1993) 5.08

GABA(B) receptors function as a heteromeric assembly of the subunits GABA(B)R1 and GABA(B)R2. Nature (1998) 5.03

Randomised controlled trial of vancomycin for pseudomembranous colitis and postoperative diarrhoea. Br Med J (1978) 4.99

Candidemia in a tertiary care hospital: epidemiology, risk factors, and predictors of mortality. Clin Infect Dis (1992) 4.98

Increased bone formation in osteocalcin-deficient mice. Nature (1996) 4.91

Twenty five years of case finding and audit in a socially deprived community. BMJ (1991) 4.89

Retinoblastoma-protein-dependent cell-cycle inhibition by the tumour suppressor p16. Nature (1995) 4.78

The DNA sequence of human herpesvirus-6: structure, coding content, and genome evolution. Virology (1995) 4.77

The BBC survey of complementary medicine use in the UK. Complement Ther Med (2000) 4.70

The complex of myxomas, spotty pigmentation, and endocrine overactivity. Medicine (Baltimore) (1985) 4.64

Does tobacco advertising target young people to start smoking? Evidence from California. JAMA (1991) 4.63

Murine model of Niemann-Pick C disease: mutation in a cholesterol homeostasis gene. Science (1997) 4.55

Treatment of human immunodeficiency virus infection with saquinavir, zidovudine, and zalcitabine. AIDS Clinical Trials Group. N Engl J Med (1996) 4.43

The objective evaluation of dysmenorrhea therapy. Am J Obstet Gynecol (1980) 4.38

Collaborative investigation of the AutoMicrobic System Enterobacteriaceae biochemical card. J Clin Microbiol (1980) 4.28

An integrative genomics approach to the reconstruction of gene networks in segregating populations. Cytogenet Genome Res (2004) 4.16

The effect of glucocorticosteroids on the kinetics of mononuclear phagocytes. J Exp Med (1970) 4.09

Infectious human herpesvirus 8 in a healthy North American blood donor. Lancet (1997) 3.93

Risk factors for sleep-disordered breathing in children. Associations with obesity, race, and respiratory problems. Am J Respir Crit Care Med (1999) 3.89

The PH domain: a common piece in the structural patchwork of signalling proteins. Trends Biochem Sci (1993) 3.89

The effect of tolerance to noninherited maternal HLA antigens on the survival of renal transplants from sibling donors. N Engl J Med (1998) 3.86

Acupuncture: safety first. BMJ (1997) 3.84

Phosphoenolpyruvate and 2-phosphoglycerate: endogenous energy source(s) for sugar accumulation by starved cells of Streptococcus lactis. J Bacteriol (1977) 3.73

A case of cholera in Texas, 1973. Am J Epidemiol (1974) 3.71

Large lung bullae in marijuana smokers. Thorax (2000) 3.70

Cre-mediated somatic site-specific recombination in mice. Nucleic Acids Res (1997) 3.70

Overexpression of cyclooxygenase-2 is sufficient to induce tumorigenesis in transgenic mice. J Biol Chem (2001) 3.69

Validation of 1989 Tennessee birth certificates using maternal and newborn hospital records. Am J Epidemiol (1993) 3.67

A second serine protease associated with mannan-binding lectin that activates complement. Nature (1997) 3.64

Effect of nicotine chewing gum as an adjunct to general practitioner's advice against smoking. Br Med J (Clin Res Ed) (1983) 3.64

Efficacy of antibiotic prophylaxis for prevention of native-valve endocarditis. Lancet (1992) 3.58

Essential role of p38alpha MAP kinase in placental but not embryonic cardiovascular development. Mol Cell (2000) 3.54

The isolation and partial characterization of neutrophil chemotactic factors from Escherichia coli. J Immunol (1975) 3.50

HNF-3A, a hepatocyte-enriched transcription factor of novel structure is regulated transcriptionally. Genes Dev (1990) 3.50

NF-kappaB function in growth control: regulation of cyclin D1 expression and G0/G1-to-S-phase transition. Mol Cell Biol (1999) 3.42

Colorectal tumors responding to 5-fluorouracil have low gene expression levels of dihydropyrimidine dehydrogenase, thymidylate synthase, and thymidine phosphorylase. Clin Cancer Res (2000) 3.42

Immunohistochemical localization of TGF beta 1, TGF beta 2, and TGF beta 3 in the mouse embryo: expression patterns suggest multiple roles during embryonic development. J Cell Biol (1991) 3.38

Randomised trial of isoniazid versus rifampicin and pyrazinamide for prevention of tuberculosis in HIV-1 infection. Lancet (1998) 3.37

Maintaining stable symptom control in inflammatory bowel disease: a retrospective analysis of adherence, medication switches and the risk of relapse. Aliment Pharmacol Ther (2013) 3.32

The Cataract National Dataset electronic multicentre audit of 55,567 operations: risk stratification for posterior capsule rupture and vitreous loss. Eye (Lond) (2008) 3.32

Consensus statement on the live organ donor. JAMA (2000) 3.29

Abacavir-lamivudine-zidovudine vs indinavir-lamivudine-zidovudine in antiretroviral-naive HIV-infected adults: A randomized equivalence trial. JAMA (2001) 3.28

Patterns of psychiatric comorbidity, cognition, and psychosocial functioning in adults with attention deficit hyperactivity disorder. Am J Psychiatry (1993) 3.27

Identification of differentially expressed mRNA species by an improved display technique (DDRT-PCR). Nucleic Acids Res (1993) 3.26

Purification and biological activity of thymosin, a hormone of the thymus gland. Proc Natl Acad Sci U S A (1972) 3.24

Chronic-disease classification in evaluation of medical care programs. Med Care (1969) 3.23

The use of DNA probes identifying restriction-fragment-length polymorphisms to examine the Mycobacterium avium complex. Mol Microbiol (1987) 3.23

Molecular interactions between Anopheles stephensi midgut cells and Plasmodium berghei: the time bomb theory of ookinete invasion of mosquitoes. EMBO J (2000) 3.22

Skin cancer in kidney and heart transplant recipients and different long-term immunosuppressive therapy regimens. J Am Acad Dermatol (1999) 3.19

Disturbance of cerebral function in people exposed to drinking water contaminated with aluminium sulphate: retrospective study of the Camelford water incident. BMJ (1999) 3.16

Statewide quality improvement initiatives and mortality after cardiac surgery. JAMA (1997) 3.16

Cyclin D1 is dispensable for G1 control in retinoblastoma gene-deficient cells independently of cdk4 activity. Mol Cell Biol (1995) 3.16

Preparation, assay, and partial purification of a thymic lymphocytopoietic factor (thymosin). Proc Natl Acad Sci U S A (1966) 3.16

Appearance of T-cell markers in bone marrow rosette-forming cells after incubation with thymosin, a thymic hormone. Proc Natl Acad Sci U S A (1971) 3.13

Heterogeneity of malignant cells from a human colonic carcinoma. Cancer Res (1981) 3.12

Mitogen-activated protein kinase p38 controls the expression and posttranslational modification of tristetraprolin, a regulator of tumor necrosis factor alpha mRNA stability. Mol Cell Biol (2001) 3.12

Randomised trial of intravenous immunoglobulin G, intravenous anti-D, and oral prednisone in childhood acute immune thrombocytopenic purpura. Lancet (1994) 3.12

Randomized controlled comparison of epidural bupivacaine versus pethidine for analgesia in labour. Br J Anaesth (2000) 2.99

Increased antifungal activity of L-733,560, a water-soluble, semisynthetic pneumocandin, is due to enhanced inhibition of cell wall synthesis. Antimicrob Agents Chemother (1994) 2.99

Induction of human IgE synthesis in B cells by mast cells and basophils. Nature (1993) 2.97

Life-threatening adverse reactions after acupuncture? A systematic review. Pain (1997) 2.96

The brain--gut pathway in functional gastrointestinal disorders is bidirectional: a 12-year prospective population-based study. Gut (2012) 2.96

cGMP mobilizes intracellular Ca2+ in sea urchin eggs by stimulating cyclic ADP-ribose synthesis. Nature (1993) 2.96

Memory interference during language processing. J Exp Psychol Learn Mem Cogn (2001) 2.92

DNA probes demonstrate a single highly conserved strain of Mycobacterium avium infecting AIDS patients. Lancet (1989) 2.91

Xkid, a chromokinesin required for chromosome alignment on the metaphase plate. Cell (2000) 2.90

Evaluation of a live, cold-passaged, temperature-sensitive, respiratory syncytial virus vaccine candidate in infancy. J Infect Dis (2000) 2.90