Published in N Engl J Med on April 12, 2001
Video decision support tool for advance care planning in dementia: randomised controlled trial. BMJ (2009) 3.55
GATA2 deficiency: a protean disorder of hematopoiesis, lymphatics, and immunity. Blood (2013) 2.82
Contribution of Alzheimer disease to mortality in the United States. Neurology (2014) 2.67
Barriers to excellent end-of-life care for patients with dementia. J Gen Intern Med (2004) 2.49
Mediterranean diet and Alzheimer disease mortality. Neurology (2007) 2.45
Survival of people with clinical diagnosis of dementia in primary care: cohort study. BMJ (2010) 2.15
Analyzing Length-biased Data with Semiparametric Transformation and Accelerated Failure Time Models. J Am Stat Assoc (2009) 1.95
Implementing a geriatric assessment in cooperative group clinical cancer trials: CALGB 360401. J Clin Oncol (2011) 1.76
Sources of variability in estimates of the prevalence of Alzheimer's disease in the United States. Alzheimers Dement (2011) 1.71
Motor signs predict poor outcomes in Alzheimer disease. Neurology (2005) 1.60
Statistical methods for analyzing right-censored length-biased data under cox model. Biometrics (2009) 1.58
Feelings of Hopelessness in Midlife and Cognitive Health in Later Life: A Prospective Population-Based Cohort Study. PLoS One (2015) 1.39
Survival in Alzheimer disease: a multiethnic, population-based study of incident cases. Neurology (2008) 1.24
Diabetes mellitus and the risk of Alzheimer's disease: a nationwide population-based study. PLoS One (2014) 1.11
Interpreting the clinical significance of capacity scores for informed consent in Alzheimer disease clinical trials. Am J Geriatr Psychiatry (2008) 1.10
How many dementia cases in France and Europe? Alternative projections and scenarios 2010-2050. Eur J Neurol (2009) 1.10
Nonparametric tests for right-censored data with biased sampling. J R Stat Soc Series B Stat Methodol (2010) 1.07
Aging and the public health effects of dementia. N Engl J Med (2001) 1.05
Nonparametric estimation for length-biased and right-censored data. Biometrika (2011) 1.04
Reversal of English trend towards hospital death in dementia: a population-based study of place of death and associated individual and regional factors, 2001-2010. BMC Neurol (2014) 1.03
Maximum Likelihood Estimations and EM Algorithms with Length-biased Data. J Am Stat Assoc (2011) 1.02
Escitalopram and enhancement of cognitive recovery following stroke. Arch Gen Psychiatry (2010) 0.99
A maximum pseudo-profile likelihood estimator for the Cox model under length-biased sampling. Biometrika (2012) 0.97
Long-term efficacy and toxicity of cholinesterase inhibitors in the treatment of Alzheimer disease. Can J Psychiatry (2014) 0.97
Mentoring junior faculty in geriatric oncology: report from the Cancer and Aging Research Group. J Clin Oncol (2008) 0.97
Physical activity and Alzheimer disease course. Am J Geriatr Psychiatry (2011) 0.96
Impact of high risk drug use on hospitalization and mortality in older people with and without Alzheimer's disease: a national population cohort study. PLoS One (2014) 0.96
Geriatric assessment in older patients with breast cancer. J Natl Compr Canc Netw (2009) 0.95
Buckley-James-type estimator with right-censored and length-biased data. Biometrics (2011) 0.94
Verbal fluency predicts mortality in Alzheimer disease. Cogn Behav Neurol (2006) 0.89
Oxidative Stress in Neurodegenerative Diseases. Mol Neurobiol (2015) 0.89
Factors affecting survival of patients with neurodegenerative disease. Neuroepidemiology (2010) 0.87
Knowledge translation on dementia: a cluster randomized trial to compare a blended learning approach with a "classical" advanced training in GP quality circles. BMC Health Serv Res (2007) 0.87
Nonparametric incidence estimation from prevalent cohort survival data. Biometrika (2012) 0.87
Dementia in the oldest old. Nat Rev Neurol (2013) 0.86
Feasibility and toxicity of dose-dense adjuvant chemotherapy in older women with breast cancer. Breast Cancer Res Treat (2008) 0.85
Likelihood approaches for the invariant density ratio model with biased-sampling data. Biometrika (2012) 0.84
Health Insurance Dynamics: Methodological Considerations and a Comparison of Estimates from Two Surveys. Health Serv Res (2016) 0.84
Empirical likelihood-based confidence intervals for length-biased data. Stat Med (2012) 0.84
Dementia / Alzheimer's Disease. BMC Womens Health (2004) 0.81
Factors that influence survival in a probable Alzheimer disease cohort. Alzheimers Res Ther (2012) 0.81
A Population-based study of dementia in the oldest old: the Monzino 80-plus study. BMC Neurol (2011) 0.81
Qualitative evaluation of advanced care planning in early dementia (ACP-ED). PLoS One (2013) 0.81
Does a single-item measure of depression predict mortality? Can Fam Physician (2009) 0.80
Mini-mental state examination as a predictor of mortality among older people referred to secondary mental healthcare. PLoS One (2014) 0.79
The perseverance time of informal carers for people with dementia: results of a two-year longitudinal follow-up study. BMC Nurs (2015) 0.79
A Bayesian MCMC approach to survival analysis with doubly-censored data. Comput Stat Data Anal (2010) 0.79
Estimating the lifetime risk of dementia in the Canadian elderly population using cross-sectional cohort survival data. J Am Stat Assoc (2015) 0.79
Development of an oncological-multidimensional prognostic index (Onco-MPI) for mortality prediction in older cancer patients. J Cancer Res Clin Oncol (2016) 0.78
Geriatric assessment factors are associated with mortality after hospitalization in older adults with cancer. Support Care Cancer (2016) 0.78
Genetic Determinants of Survival in Patientswith Alzheimer’s Disease. J Alzheimers Dis (2015) 0.78
[Comorbidity oriented oncology - an overview]. Wien Klin Wochenschr (2010) 0.78
Stroke, dementia, and drug delivery. Br J Clin Pharmacol (2004) 0.77
Score Estimating Equations from Embedded Likelihood Functions under Accelerated Failure Time Model. J Am Stat Assoc (2014) 0.77
Prescribing for Australians living with dementia: study protocol using the Delphi technique. BMJ Open (2015) 0.77
Semiparametric estimation for the additive hazards model with left-truncated and right-censored data. Biometrika (2015) 0.77
Family caregivers' role implementation at different stages of dementia. Clin Interv Aging (2015) 0.77
Semiparametric Accelerated Failure Time Model for Length-biased Data with Application to Dementia Study. Stat Sin (2014) 0.77
Composite Partial Likelihood Estimation Under Length-Biased Sampling, With Application to a Prevalent Cohort Study of Dementia. J Am Stat Assoc (2012) 0.77
The natural history of early-onset dementia: the Artemis Project. BMJ Open (2012) 0.76
Medication appropriateness tool for co-morbid health conditions in dementia: consensus recommendations from a multidisciplinary expert panel. Intern Med J (2016) 0.75
Special considerations for endoscopists on PEG indications in older patients. ISRN Gastroenterol (2012) 0.75
Longitudinal Changes in the Government-Certified Index Stage and Requisite Costs for Long-Term Care Insurance System among the Community-Dwelling Demented Elderly in Japan. Int J Alzheimers Dis (2013) 0.75
Propensity Score Estimation in the Presence of Length-biased Sampling: A Nonparametric Adjustment Approach. Stat (2014) 0.75
Survival analysis without survival data: connecting length-biased and case-control data. Biometrika (2013) 0.75
Geriatric oncology: The need for a separate subspecialty. Indian J Med Paediatr Oncol (2012) 0.75
Sample size calculations for prevalent cohort designs. Stat Methods Med Res (2014) 0.75
The association between caregiver well-being and care provided to persons with Alzheimer's disease and related disorders. BMC Res Notes (2016) 0.75
Prognosis of patients with dementia: results from a prospective nationwide registry linkage study in the Netherlands. BMJ Open (2015) 0.75
Long-term effect of galantamine on cognitive function in patients with Alzheimer's disease versus a simulated disease trajectory: an observational study in the clinical setting. Neuropsychiatr Dis Treat (2017) 0.75
Semiparametric likelihood inference for left-truncated and right-censored data. Biostatistics (2015) 0.75
Rank-based testing of equal survivorship based on cross-sectional survival data with or without prospective follow-up. Biostatistics (2015) 0.75
The Effects of Anti-Dementia and Nootropic Treatments on the Mortality of Patients with Dementia: A Population-Based Cohort Study in Taiwan. PLoS One (2015) 0.75
Nonparametric and semiparametric regression estimation for length-biased survival data. Lifetime Data Anal (2016) 0.75
Increased longevity in offspring of mothers with Alzheimer's disease. Am J Med Genet B Neuropsychiatr Genet (2008) 0.75
Cognitively-Related Basic Activities of Daily Living Impairment Greatly Increases the Risk of Death in Alzheimers Disease. PLoS One (2016) 0.75
Alzheimer's disease, anesthesia and the cholinergic system. J Anaesthesiol Clin Pharmacol (2011) 0.75
Understanding cognition in older patients with cancer. J Geriatr Oncol (2016) 0.75
Comprehensive geriatric assessment in the older cancer patient: coming of age in clinical cancer care. Clin Pract (Lond) (2015) 0.75
Profile of atypical-antipsychotics use in patients affected by dementia in the University Hospital of Ferrara. Eur J Clin Pharmacol (2010) 0.75
Physical activity and risk of cognitive impairment and dementia in elderly persons. Arch Neurol (2001) 4.56
Accumulation of deficits as a proxy measure of aging. ScientificWorldJournal (2001) 4.47
Prevalence and severity of cognitive impairment with and without dementia in an elderly population. Lancet (1997) 4.39
A phenomenology of scut. Ann Intern Med (1991) 3.46
A brief clinical instrument to classify frailty in elderly people. Lancet (1999) 3.27
The recognition, assessment and management of dementing disorders: conclusions from the Canadian Consensus Conference on Dementia. CMAJ (1999) 3.14
Pharmacotherapy of Alzheimer's disease: is there a need to redefine treatment success? Int J Geriatr Psychiatry (2001) 3.09
The search for an ideal method of abdominal fascial closure: a meta-analysis. Ann Surg (2000) 2.59
Research criteria for subcortical vascular dementia in clinical trials. J Neural Transm Suppl (2000) 2.56
The effect of different diagnostic criteria on the prevalence of dementia. N Engl J Med (1997) 2.52
The London Fibromyalgia Epidemiology Study: the prevalence of fibromyalgia syndrome in London, Ontario. J Rheumatol (1999) 2.44
The rational clinical examination. Does this patient have a clinically important carotid bruit? JAMA (1993) 2.38
Predictors of loss of residual renal function among new dialysis patients. J Am Soc Nephrol (2000) 2.16
Prevalence and types of dementia in the very old: results from the Canadian Study of Health and Aging. Neurology (1994) 2.10
Conceptualisation and measurement of frailty in elderly people. Drugs Aging (2000) 2.00
A general population study of fibromyalgia tender points in noninstitutionalized adults with chronic widespread pain. J Rheumatol (2000) 1.98
Occupational exposure to pesticides increases the risk of incident AD: the Cache County study. Neurology (2010) 1.95
Multiple sclerosis: a comparison of the latent periods of different populations. Neuroepidemiology (1993) 1.94
Competencies required for the practice of geriatric medicine as a consultant physician. CMAJ (1989) 1.67
Cognitive impairment in the nondemented elderly. Results from the Canadian Study of Health and Aging. Arch Neurol (1995) 1.66
Screening for PS1 mutations in a referral-based series of AD cases: 21 novel mutations. Neurology (2001) 1.64
Calcium-channel blockers and cognitive function in elderly people: results from the Canadian Study of Health and Aging. CMAJ (1999) 1.60
Bovine spongiform encephalopathy and Creutzfeldt-Jakob disease: implications for physicians. CMAJ (1996) 1.57
Prevalence and outcomes of vascular cognitive impairment. Vascular Cognitive Impairment Investigators of the Canadian Study of Health and Aging. Neurology (2000) 1.49
The prevalence of cognitive impairment in an elderly Canadian population. Acta Psychiatr Scand (1989) 1.48
Effect of a geriatric consultation service on management of patients in an acute care hospital. CMAJ (1987) 1.48
Illness presentation in elderly patients. Arch Intern Med (1995) 1.43
Environmental exposures in elderly Canadians with Parkinson's disease. Can J Neurol Sci (1995) 1.43
The latent period of multiple sclerosis: a critical review. Epidemiology (1993) 1.41
Health behaviours and socio-economic status in Ontario, Canada. Eur J Epidemiol (1997) 1.40
Testing an instrument to screen for fibromyalgia syndrome in general population studies: the London Fibromyalgia Epidemiology Study Screening Questionnaire. J Rheumatol (1999) 1.39
Behavioral problems in nursing home residents. Safe ways to manage dementia. Postgrad Med (1995) 1.38
Vascular dementia : incidence and risk factors in the Canadian study of health and aging. Stroke (2000) 1.35
Canadian Consensus Conference on Dementia: a physician's guide to using the recommendations. CMAJ (1999) 1.34
Complementary/alternative medicine: comparing the view of medical students with students in other health care professions. Fam Med (2000) 1.32
Multidimensionality in instrumental and basic activities of daily living. J Clin Epidemiol (1998) 1.32
Progression of impairment in patients with vascular cognitive impairment without dementia. Neurology (2001) 1.31
Small-group CME using e-mail discussions. Can it work? Can Fam Physician (2001) 1.30
The recognition, assessment and management of dementing disorders: conclusions from the Canadian Consensus Conference on Dementia. Can J Neurol Sci (2001) 1.27
The London Fibromyalgia Epidemiology Study: direct health care costs of fibromyalgia syndrome in London, Canada. J Rheumatol (1999) 1.25
Effect of smoking on the accumulation of deficits, frailty and survival in older adults: a secondary analysis from the Canadian Study of Health and Aging. J Nutr Health Aging (2009) 1.22
Testing the measurement properties of the Short Form-36 Health Survey in a frail elderly population. J Clin Epidemiol (1998) 1.21
Comparing self-reported function and work disability in 100 community cases of fibromyalgia syndrome versus controls in London, Ontario: the London Fibromyalgia Epidemiology Study. Arthritis Rheum (1999) 1.20
The effect of middle- and old-age body mass index on short-term mortality in older people. J Am Geriatr Soc (2001) 1.20
Time since immigration and excess body weight. Can J Public Health (1999) 1.18
Frailty in relation to the risk of falls, fractures, and mortality in older Chinese adults: results from the Beijing Longitudinal Study of Aging. J Nutr Health Aging (2012) 1.17
The use of goal attainment scaling in a geriatric care setting. J Am Geriatr Soc (1992) 1.17
Post-term birth: risk factors and outcomes in a 10-year cohort of Norwegian births. Obstet Gynecol (1997) 1.16
Pain and pain-related interference with function in older Canadians: the Canadian Study of Health and Aging. Disabil Rehabil (2001) 1.15
Standardization of the diagnosis of dementia in the Canadian Study of Health and Aging. Neuroepidemiology (1996) 1.15
Rasch analysis of the hierarchical assessment of balance and mobility (HABAM). J Clin Epidemiol (2000) 1.14
The Canadian Study of Health and Aging: risk factors for vascular dementia. Stroke (1997) 1.13
The atypical presentation of infection in old age. Age Ageing (1987) 1.13
The London Fibromyalgia Epidemiology Study: comparing the demographic and clinical characteristics in 100 random community cases of fibromyalgia versus controls. J Rheumatol (1999) 1.11
Transitions in cognitive status in relation to frailty in older adults: a comparison of three frailty measures. J Nutr Health Aging (2011) 1.09
IVF births and pregnancies: an exploration of two methods of assessment using life-table analysis. J Assist Reprod Genet (2001) 1.06
Goal attainment scaling as a measure of clinically important change in nursing-home patients. Age Ageing (1999) 1.05
A Hierarchical Assessment of Balance and Mobility. Age Ageing (1995) 1.05
A randomized controlled trial to compare the efficacy of cyclical parathyroid hormone versus cyclical parathyroid hormone and sequential calcitonin to improve bone mass in postmenopausal women with osteoporosis. J Clin Endocrinol Metab (1997) 1.04
4th Canadian Consensus Conference on the Diagnosis and Treatment of Dementia. Can J Neurol Sci (2012) 1.03
Patient satisfaction as an indicator of quality care in independent health facilities: developing and assessing a tool to enhance public accountability. Am J Med Qual (2000) 1.03
Comparison of the prognostic importance of diagnosed diabetes, co-morbidity and frailty in older people. Diabet Med (2010) 1.01
Reliability and validity of questions about exercise in the Canadian Study of Health and Aging. Int Psychogeriatr (2001) 1.01
A Canadian cohort study of cognitive impairment and related dementias (ACCORD): study methods and baseline results. Neuroepidemiology (2003) 1.01
The association between parkinsonism, Alzheimer's disease, and mortality: a comprehensive approach. J Am Geriatr Soc (2000) 1.00
User fees for health services. Norwegian perspective on copayments. Can Fam Physician (1996) 1.00
Folate status, vascular disease and cognition in elderly Canadians. Age Ageing (1998) 1.00
Potential adverse outcomes of psychotropic and narcotic drug use in Canadian seniors. J Clin Epidemiol (1997) 1.00
Limitations of clinical criteria for the diagnosis of vascular dementia in clinical trials. Is a focus on subcortical vascular dementia a solution? Ann N Y Acad Sci (2000) 1.00
The influence of venous thromboembolism on quality of life and severity of chronic venous disease. J Thromb Haemost (2004) 0.99
Disease progression in vascular cognitive impairment: cognitive, functional and behavioural outcomes in the Consortium to Investigate Vascular Impairment of Cognition (CIVIC) cohort study. J Neurol Sci (2006) 0.99
Donepezil for treatment of dementia with Lewy bodies: a case series of nine patients. Int Psychogeriatr (1998) 0.99
Co-existence of chronic fatigue syndrome with fibromyalgia syndrome in the general population. A controlled study. Scand J Rheumatol (2000) 0.99
Potential underreporting of energy intake in the Ontario Health Survey and its relationship with nutrient and food intakes. Eur J Epidemiol (1999) 0.98
Incidence and risk factors for delirium and other adverse outcomes in older adults after coronary artery bypass graft surgery. Can J Cardiol (1999) 0.97
Food advertising during children's television in Canada and the UK. Arch Dis Child (2009) 0.97
Outcomes of coronary artery bypass surgery in elderly people. Can J Cardiol (1998) 0.97
The rate of decline in function in Alzheimer's disease and other dementias. J Gerontol A Biol Sci Med Sci (1999) 0.96
Aging and heparin-related bleeding. Arch Intern Med (1996) 0.96
Hospitalization and case-fatality rates for stroke in Canada from 1982 through 1991. The Canadian Collaborative Study Group of Stroke Hospitalizations. Stroke (1996) 0.96
An individualized approach to outcome measurement in geriatric rehabilitation. J Gerontol A Biol Sci Med Sci (1999) 0.95
Validity of the confusion assessment method in detecting postoperative delirium in the elderly. Int Psychogeriatr (1999) 0.95
Trajectories of changes over twelve years in the health status of Canadians from late middle age. Exp Gerontol (2012) 0.94
A vascular risk factor index in relation to mortality and incident dementia. Eur J Neurol (2006) 0.94
Nifedipine and mortality risk in the elderly: relevance of drug formulation, dose and duration. Pharmacoepidemiol Drug Saf (2000) 0.93
Outcomes of incident mild cognitive impairment in relation to case definition. J Neurol Neurosurg Psychiatry (2005) 0.93
Promoting access to innovation for frail old persons. IAGG (International Association of Gerontology and Geriatrics), WHO (World Health Organization) and SFGG (Société Française de Gériatrie et de Gérontologie) Workshop--Athens January 20-21, 2012. J Nutr Health Aging (2013) 0.92
Qualitative analysis of the clinician interview-based impression of change (Plus): methodological issues and implications for clinical research. Int Psychogeriatr (2000) 0.92
Hypophosphatemic osteomalacia complicating von Recklinghausen's neurofibromatosis: increase in spinal density on treatment. Bone (1986) 0.92
An evaluation of several biochemical markers for bone formation and resorption in a protocol utilizing cyclical parathyroid hormone and calcitonin therapy for osteoporosis. J Clin Invest (1993) 0.91
Development of public health training in Hungary--an exercise in international co-operation. J Public Health Med (1995) 0.91
Gait and posture impairment, parkinsonism and cognitive decline in older people. J Neural Transm (Vienna) (2007) 0.91
A comparison of methods for measuring socio-economic status by occupation or postal area. Chronic Dis Can (2000) 0.90
Validity and reliability of the Medical Outcomes Study Short Form-20 questionnaire as a measure of quality of life in elderly people living at home. Age Ageing (1999) 0.90
Predictors of dietary intake in Ontario seniors. Can J Public Health (1998) 0.90
Small area variation in low birthweight: looking beyond socioeconomic predictors. Can J Public Health (1997) 0.90
Teaching statistics to health professionals: the legal analogy. Med Teach (1992) 0.89