Published in J Biol Chem on April 16, 2001
Repression of Runx2 function by TGF-beta through recruitment of class II histone deacetylases by Smad3. EMBO J (2005) 2.35
Transforming growth factor beta-mediated transcriptional repression of c-myc is dependent on direct binding of Smad3 to a novel repressive Smad binding element. Mol Cell Biol (2004) 1.77
Essential role of TGF-beta signaling in glucose-induced cell hypertrophy. Dev Cell (2009) 1.40
microRNA are Central Players in Anti- and Profibrotic Gene Regulation during Liver Fibrosis. Front Physiol (2012) 1.20
Smad6 recruits transcription corepressor CtBP to repress bone morphogenetic protein-induced transcription. Mol Cell Biol (2003) 1.13
Ligand-dependent ubiquitination of Smad3 is regulated by casein kinase 1 gamma 2, an inhibitor of TGF-beta signaling. Oncogene (2008) 0.90
Repression of Smad2 and Smad3 transactivating activity by association with a novel splice variant of CCAAT-binding factor C subunit. Biochem J (2002) 0.81
By the company they keep: interaction networks define the binding ability of transcription factors. Nucleic Acids Res (2015) 0.77
A complex containing N-CoR, mSin3 and histone deacetylase mediates transcriptional repression. Nature (1997) 9.71
TGF beta signals through a heteromeric protein kinase receptor complex. Cell (1992) 8.12
Histone deacetylases associated with the mSin3 corepressor mediate mad transcriptional repression. Cell (1997) 7.64
Expression cloning of the TGF-beta type II receptor, a functional transmembrane serine/threonine kinase. Cell (1992) 4.68
Transforming growth factor beta induces the cyclin-dependent kinase inhibitor p21 through a p53-independent mechanism. Proc Natl Acad Sci U S A (1995) 4.54
Sodium butyrate inhibits histone deacetylation in cultured cells. Cell (1978) 4.20
Isolation and characterization of cDNAs corresponding to an additional member of the human histone deacetylase gene family. J Biol Chem (1997) 4.16
Regulation of neuronal traits by a novel transcriptional complex. Neuron (2001) 4.02
Deletions of a DNA sequence in retinoblastomas and mesenchymal tumors: organization of the sequence and its encoded protein. Proc Natl Acad Sci U S A (1987) 3.72
Targeted disruption of Smad3 reveals an essential role in transforming growth factor beta-mediated signal transduction. Mol Cell Biol (1999) 3.55
The human factors YY1 and LSF repress the human immunodeficiency virus type 1 long terminal repeat via recruitment of histone deacetylase 1. J Virol (2000) 3.43
ETO, a target of t(8;21) in acute leukemia, interacts with the N-CoR and mSin3 corepressors. Mol Cell Biol (1998) 3.06
Transcriptional enhancer elements in the mouse immunoglobulin heavy chain locus. Science (1983) 2.75
Rapid deubiquitination of nucleosomal histones in human tumor cells caused by proteasome inhibitors and stress response inducers: effects on replication, transcription, translation, and the cellular stress response. Biochemistry (1997) 2.73
SAP30, a component of the mSin3 corepressor complex involved in N-CoR-mediated repression by specific transcription factors. Mol Cell (1998) 2.60
5-Methylcytosine is not detectable in Saccharomyces cerevisiae DNA. Mol Cell Biol (1984) 2.52
ATR/ATM-mediated phosphorylation of human Rad17 is required for genotoxic stress responses. Nature (2001) 2.50
Functional analysis of the transforming growth factor beta responsive elements in the WAF1/Cip1/p21 promoter. J Biol Chem (1995) 2.35
A transforming growth factor beta type I receptor that signals to activate gene expression. Science (1994) 2.26
Tumor suppressor Smad4 is a transforming growth factor beta-inducible DNA binding protein. Mol Cell Biol (1997) 2.25
Increased Ser-10 phosphorylation of histone H3 in mitogen-stimulated and oncogene-transformed mouse fibroblasts. J Biol Chem (1999) 2.24
Nodeless superconducting gap in A(x)Fe2Se2 (A=K,Cs) revealed by angle-resolved photoemission spectroscopy. Nat Mater (2011) 2.16
Smad3-Smad4 and AP-1 complexes synergize in transcriptional activation of the c-Jun promoter by transforming growth factor beta. Mol Cell Biol (1999) 2.08
Role of covalent modifications of histones in regulating gene expression. Gene (1999) 1.92
Host-mediated selection of influenza virus receptor variants. Sialic acid-alpha 2,6Gal-specific clones of A/duck/Ukraine/1/63 revert to sialic acid-alpha 2,3Gal-specific wild type in ovo. J Biol Chem (1985) 1.91
The role of Smad3 in mediating mouse hepatic stellate cell activation. Hepatology (2001) 1.88
Expression of the E2F1 transcription factor overcomes type beta transforming growth factor-mediated growth suppression. Proc Natl Acad Sci U S A (1995) 1.81
Smads bind directly to the Jun family of AP-1 transcription factors. Proc Natl Acad Sci U S A (1999) 1.81
Expression of transforming growth factor beta type II receptor leads to reduced malignancy in human breast cancer MCF-7 cells. J Biol Chem (1994) 1.76
Transforming growth factor beta activates the promoter of cyclin-dependent kinase inhibitor p15INK4B through an Sp1 consensus site. J Biol Chem (1995) 1.72
Absence of TGF-beta receptors and growth inhibitory responses in retinoblastoma cells. Science (1988) 1.72
Quantum criticality and nodal superconductivity in the FeAs-based superconductor KFe2As2. Phys Rev Lett (2010) 1.68
TGF-beta-induced phosphorylation of Smad3 regulates its interaction with coactivator p300/CREB-binding protein. Mol Biol Cell (1998) 1.67
Mammalian dwarfins are phosphorylated in response to transforming growth factor beta and are implicated in control of cell growth. Proc Natl Acad Sci U S A (1996) 1.67
A genetically tractable model of human glioma formation. Cancer Res (2001) 1.63
Analysis of simulated and experimental fluorescence recovery after photobleaching. Data for two diffusing components. Biophys J (1995) 1.60
Chicken erythrocyte polynucleosomes which are soluble at physiological ionic strength and contain linker histones are highly enriched in beta-globin gene sequences. Nucleic Acids Res (1987) 1.56
Smad5 induces ventral fates in Xenopus embryo. Dev Biol (1997) 1.49
The loss of Smad3 results in a lower rate of bone formation and osteopenia through dysregulation of osteoblast differentiation and apoptosis. J Bone Miner Res (2001) 1.44
Ubiquitinated histone H2B is preferentially located in transcriptionally active chromatin. Biochemistry (1989) 1.44
Characterisation and validation of a novel panel of the six short tandem repeats for genetic counselling in Chinese haemophilia A pedigrees. Haemophilia (2012) 1.42
Direct visualization of the human estrogen receptor alpha reveals a role for ligand in the nuclear distribution of the receptor. Mol Biol Cell (1999) 1.40
Drosophila C-terminal binding protein functions as a context-dependent transcriptional co-factor and interferes with both mad and groucho transcriptional repression. J Biol Chem (2000) 1.39
In vivo functional analysis of in vitro protein binding sites in the immunoglobulin heavy chain enhancer. Nucleic Acids Res (1988) 1.39
The endogenous immunoglobulin heavy chain enhancer can activate tandem VH promoters separated by a large distance. Cell (1985) 1.39
Acetylated histone H4 is preferentially associated with template-active chromatin. Proc Natl Acad Sci U S A (1978) 1.34
Nomenclature: vertebrate mediators of TGFbeta family signals. Cell (1996) 1.34
Efficient method for visualization and isolation of proteins resolved in polyacrylamide gels. J Chromatogr (1984) 1.33
SV40 enhancer-binding factors are required at the establishment but not the maintenance step of enhancer-dependent transcriptional activation. Cell (1986) 1.32
Common crystalline and magnetic structure of superconducting A2Fe4Se5 (A=K,Rb,Cs,Tl) single crystals measured using neutron diffraction. Phys Rev Lett (2011) 1.32
Risk factors for surgical site infections after breast surgery: a systematic review and meta-analysis. Eur J Surg Oncol (2012) 1.31
The activity of guanine exchange factor NET1 is essential for transforming growth factor-beta-mediated stress fiber formation. J Biol Chem (2001) 1.31
Scanning tunneling spectroscopy and vortex imaging in the iron pnictide superconductor BaFe1.8Co0.2As2. Phys Rev Lett (2009) 1.29
Ultrastructural organization of yeast chromatin. J Cell Biol (1982) 1.28
Histone acetylation alters the capacity of the H1 histones to condense transcriptionally active/competent chromatin. J Biol Chem (1990) 1.27
Inhibition of the 3-hydroxy-3-methylglutaryl-coenzyme A reductase pathway induces p53-independent transcriptional regulation of p21(WAF1/CIP1) in human prostate carcinoma cells. J Biol Chem (1998) 1.27
Cooperation of Sp1 and p300 in the induction of the CDK inhibitor p21WAF1/CIP1 during NGF-mediated neuronal differentiation. Oncogene (1999) 1.26
Clinical and immunohistochemical evidence for an X linked retinitis pigmentosa syndrome with recurrent infections and hearing loss in association with an RPGR mutation. J Med Genet (2003) 1.26
Molecular mechanisms of transforming growth factor-beta signaling. Endocr Rev (1998) 1.26
The MEK pathway is required for stimulation of p21(WAF1/CIP1) by transforming growth factor-beta. J Biol Chem (1999) 1.25
Differential salt fractionation of active and inactive genomic domains in chicken erythrocyte. J Biol Chem (1984) 1.24
Effects of histone acetylation, ubiquitination and variants on nucleosome stability. Biochem J (1993) 1.24
Chemical composition of nucleosomes among domains of calf thymus chromatin differing in micrococcal nuclease accessibility and solubility properties. J Biol Chem (1981) 1.22
The viral oncoprotein E1A blocks transforming growth factor beta-mediated induction of p21/WAF1/Cip1 and p15/INK4B. Mol Cell Biol (1997) 1.17
Effect of estradiol on histone acetylation dynamics in human breast cancer cells. J Biol Chem (2001) 1.17
Tamoxifen-bound estrogen receptor (ER) strongly interacts with the nuclear matrix protein HET/SAF-B, a novel inhibitor of ER-mediated transactivation. Mol Endocrinol (2000) 1.16
Histone modifications in the yeast S. Cerevisiae. Nucleic Acids Res (1981) 1.15
Anomalous transport properties and phase diagram of the FeAs-based SmFeAsO1-xFx superconductors. Phys Rev Lett (2008) 1.14
Histone acetyltransferase is associated with the nuclear matrix. J Biol Chem (1994) 1.11
Transforming growth factor-beta-mediated p15(INK4B) induction and growth inhibition in astrocytes is SMAD3-dependent and a pathway prominently altered in human glioma cell lines. J Biol Chem (1999) 1.11
Smart nanofibers from combined living radical polymerization, "click chemistry", and electrospinning. ACS Appl Mater Interfaces (2009) 1.10
Chromatin structure of erythroid-specific genes of immature and mature chicken erythrocytes. Biochem J (1989) 1.10
Ubiquitination of histone H3 in elongating spermatids of rat testes. J Biol Chem (1998) 1.10
Structure of polyubiquitinated histone H2A. Biochemistry (1989) 1.10
Distribution of methylated histones and histone methyltransferases in chicken erythrocyte chromatin. J Biol Chem (1989) 1.08
Increased phosphorylation of histone H1 in mouse fibroblasts transformed with oncogenes or constitutively active mitogen-activated protein kinase kinase. J Biol Chem (1995) 1.08
Histone deacetylase is a component of the internal nuclear matrix. J Biol Chem (1991) 1.07
Novel nuclear matrix protein HET binds to and influences activity of the HSP27 promoter in human breast cancer cells. J Cell Biochem (1997) 1.06
Transforming growth factor beta stimulates the human immunodeficiency virus 1 enhancer and requires NF-kappaB activity. Mol Cell Biol (1998) 1.06
E2F4-RB and E2F4-p107 complexes suppress gene expression by transforming growth factor beta through E2F binding sites. Proc Natl Acad Sci U S A (1997) 1.05
Observation of a charged charmoniumlike structure in e+ e- → π+ π- J/ψ at sqrt[s] = 4.26 GeV. Phys Rev Lett (2013) 1.05
Inducible upregulation of oestrogen receptor-beta1 affects oestrogen and tamoxifen responsiveness in MCF7 human breast cancer cells. J Mol Endocrinol (2005) 1.04
Rapid induction of histone hyperacetylation and cellular differentiation in human breast tumor cell lines following degradation of histone deacetylase-1. J Biol Chem (2000) 1.04
Changes in the histone H2A variant H2A.Z and polyubiquitinated histone species in developing trout testis. Biochemistry (1987) 1.02
Histones of Chlamydomonas reinhardtii. Synthesis, acetylation, and methylation. Plant Physiol (1995) 1.01
Sp1, but not Sp3, functions to mediate promoter activation by TGF-beta through canonical Sp1 binding sites. Nucleic Acids Res (1998) 1.01
Two-dimensional gel systems for rapid histone analysis for use in minislab polyacrylamide gel electrophoresis. Anal Biochem (1982) 1.00
Electronic-structure-driven magnetic and structure transitions in superconducting NaFeAs single crystals measured by angle-resolved photoemission spectroscopy. Phys Rev Lett (2010) 0.99
Creutzfeldt-Jakob disease in a Chinese patient with a novel seven extra-repeat insertion in PRNP. J Neurol Neurosurg Psychiatry (2007) 0.99
Regulation of a bifunctional mRNA results in synthesis of secreted and nuclear probasin. Proc Natl Acad Sci U S A (1989) 0.99
Electronic structure and unusual exchange splitting in the spin-density-wave state of the BaFe2As2 parent compound of iron-based superconductors. Phys Rev Lett (2009) 0.99
A single heteromeric receptor complex is sufficient to mediate biological effects of transforming growth factor-beta ligands. J Biol Chem (1994) 0.98
Dynamically acetylated histones of chicken erythrocytes are selectively methylated. Biochem J (1991) 0.97
Influence of livestock husbandry on schistosomiasis transmission in mountainous regions of Yunnan Province. Southeast Asian J Trop Med Public Health (1997) 0.97