Published in Science on May 11, 2001
Post-translational regulation of the microtubule cytoskeleton: mechanisms and functions. Nat Rev Mol Cell Biol (2011) 3.53
The concept of self-organization in cellular architecture. J Cell Biol (2001) 3.49
Spontaneous motion in hierarchically assembled active matter. Nature (2012) 3.22
Polar patterns of driven filaments. Nature (2010) 2.63
Generic theory of active polar gels: a paradigm for cytoskeletal dynamics. Eur Phys J E Soft Matter (2005) 2.41
Mechanisms for focusing mitotic spindle poles by minus end-directed motor proteins. J Cell Biol (2005) 2.21
Topology and dynamics of active nematic vesicles. Science (2014) 2.14
Computer simulations reveal motor properties generating stable antiparallel microtubule interactions. J Cell Biol (2002) 2.01
Ase1p organizes antiparallel microtubule arrays during interphase and mitosis in fission yeast. Mol Biol Cell (2005) 1.95
Near-critical phenomena in intracellular metabolite pools. Biophys J (2003) 1.92
Efficient formation of bipolar microtubule bundles requires microtubule-bound gamma-tubulin complexes. J Cell Biol (2005) 1.88
Large-scale vortex lattice emerging from collectively moving microtubules. Nature (2012) 1.85
Microtubule organization by the antagonistic mitotic motors kinesin-5 and kinesin-14. J Cell Biol (2010) 1.74
Kinesin and dynein-dynactin at intersecting microtubules: motor density affects dynein function. Biophys J (2008) 1.70
Active multistage coarsening of actin networks driven by myosin motors. Proc Natl Acad Sci U S A (2011) 1.56
Spatial organization of intracellular communication: insights from imaging. Nat Rev Mol Cell Biol (2010) 1.55
Cilia-like beating of active microtubule bundles. Science (2011) 1.46
The kinesin-14 Klp2 organizes microtubules into parallel bundles by an ATP-dependent sorting mechanism. Nat Cell Biol (2009) 1.45
Biology under construction: in vitro reconstitution of cellular function. Nat Rev Mol Cell Biol (2009) 1.44
Assembly pathway of the anastral Drosophila oocyte meiosis I spindle. J Cell Sci (2005) 1.40
Fast fluorescence microscopy for imaging the dynamics of embryonic development. HFSP J (2008) 1.34
Reconstitution of the transition from lamellipodium to filopodium in a membrane-free system. Proc Natl Acad Sci U S A (2006) 1.25
A force balance model of early spindle pole separation in Drosophila embryos. Biophys J (2003) 1.25
A mechanistic model for the organization of microtubule asters by motor and non-motor proteins in a mammalian mitotic extract. Mol Biol Cell (2004) 1.23
Clustering of centralspindlin is essential for its accumulation to the central spindle and the midbody. Curr Biol (2009) 1.23
Mechanisms of self-organization of cortical microtubules in plants revealed by computational simulations. Mol Biol Cell (2009) 1.20
Molecules into cells: specifying spatial architecture. Microbiol Mol Biol Rev (2005) 1.13
Cytoplasmic dynein nucleates microtubules to organize them into radial arrays in vivo. Mol Biol Cell (2004) 1.11
Concerted effort of centrosomal and Golgi-derived microtubules is required for proper Golgi complex assembly but not for maintenance. Mol Biol Cell (2012) 1.10
Self-organization of an acentrosomal microtubule network at the basal cortex of polarized epithelial cells. J Cell Biol (2005) 1.10
Proper organization of microtubule minus ends is needed for midzone stability and cytokinesis. Curr Biol (2010) 1.08
Building complexity: insights into self-organized assembly of microtubule-based architectures. Dev Cell (2012) 1.06
Topological structure dynamics revealing collective evolution in active nematics. Nat Commun (2013) 1.05
Cytoskeletal mechanisms for breaking cellular symmetry. Cold Spring Harb Perspect Biol (2010) 1.04
Self-organized density patterns of molecular motors in arrays of cytoskeletal filaments. Biophys J (2005) 1.03
Nonlinear competition between asters and stripes in filament-motor systems. Eur Phys J E Soft Matter (2005) 1.02
Microtubule organization in three-dimensional confined geometries: evaluating the role of elasticity through a combined in vitro and modeling approach. Biophys J (2006) 1.01
Approaching the molecular origins of collective dynamics in oscillating cell populations. Curr Opin Genet Dev (2010) 1.00
Multiscale polar theory of microtubule and motor-protein assemblies. Phys Rev Lett (2015) 0.99
The kinesin ATK5 functions in early spindle assembly in Arabidopsis. Plant Cell (2007) 0.98
Defect dynamics in active nematics. Philos Trans A Math Phys Eng Sci (2014) 0.98
Active contractility in actomyosin networks. Proc Natl Acad Sci U S A (2012) 0.97
Cortical instability drives periodic supracellular actin pattern formation in epithelial tubes. Proc Natl Acad Sci U S A (2015) 0.95
Active contraction of microtubule networks. Elife (2015) 0.95
Three subsets of sequence complexity and their relevance to biopolymeric information. Theor Biol Med Model (2005) 0.93
Biophysical model of self-organized spindle formation patterns without centrosomes and kinetochores. Proc Natl Acad Sci U S A (2006) 0.92
Cytoplasmic streaming in plant cells emerges naturally by microfilament self-organization. Proc Natl Acad Sci U S A (2013) 0.92
Emergent complexity of the cytoskeleton: from single filaments to tissue. Adv Phys (2013) 0.92
Hierarchical self-assembly of actin in micro-confinements using microfluidics. Biomicrofluidics (2012) 0.91
Transport and self-organization across different length scales powered by motor proteins and programmed by DNA. Nat Nanotechnol (2013) 0.91
Microtubule stability studied by three-dimensional molecular theory of solvation. Biophys J (2006) 0.91
Chromosome positioning from activity-based segregation. Nucleic Acids Res (2014) 0.90
A mechanochemical model explains interactions between cortical microtubules in plants. Biophys J (2010) 0.89
Tunable dynamics of microtubule-based active isotropic gels. Philos Trans A Math Phys Eng Sci (2014) 0.88
A formin-nucleated actin aster concentrates cell wall hydrolases for cell fusion in fission yeast. J Cell Biol (2015) 0.87
Dynamics and mechanics of motor-filament systems. Eur Phys J E Soft Matter (2006) 0.87
Biophysically realistic filament bending dynamics in agent-based biological simulation. PLoS One (2009) 0.85
Roles for kinesin and myosin during cytokinesis. Philos Trans R Soc Lond B Biol Sci (2002) 0.84
Control of active liquid crystals with a magnetic field. Proc Natl Acad Sci U S A (2016) 0.83
A mechanism for the polarity formation of chemoreceptors at the growth cone membrane for gradient amplification during directional sensing. PLoS One (2010) 0.83
Kinesin-12 motors cooperate to suppress microtubule catastrophes and drive the formation of parallel microtubule bundles. Proc Natl Acad Sci U S A (2016) 0.83
Motor-mediated cortical versus astral microtubule organization in lipid-monolayered droplets. J Biol Chem (2014) 0.82
Assembly and positioning of actomyosin rings by contractility and planar cell polarity. Elife (2015) 0.81
Active polar fluid flow in finite droplets. Eur Phys J E Soft Matter (2014) 0.81
Microscopic origins of anisotropic active stress in motor-driven nematic liquid crystals. Soft Matter (2016) 0.81
Understanding phase behavior of plant cell cortex microtubule organization. Proc Natl Acad Sci U S A (2010) 0.80
Self-organizing actin patterns shape membrane architecture but not cell mechanics. Nat Commun (2017) 0.79
Actomyosin dynamics drive local membrane component organization in an in vitro active composite layer. Proc Natl Acad Sci U S A (2016) 0.79
Systems ecology: Biology on the high seas. Nature (2013) 0.78
Spatiotemporal dynamics of actomyosin networks. Biophys J (2013) 0.78
Active actin gels. Commun Integr Biol (2012) 0.78
In vitro reconstitution of the initial stages of the bacterial cell division machinery. J Biol Phys (2008) 0.78
Active matter: Spontaneous flows and self-propelled drops. Nature (2012) 0.78
Quantitative analysis of cellular metabolic dissipative, self-organized structures. Int J Mol Sci (2010) 0.78
Altered nucleotide-microtubule coupling and increased mechanical output by a kinesin mutant. PLoS One (2012) 0.78
Dynamic structure of active nematic shells. Nat Commun (2016) 0.78
Active polar two-fluid macroscopic dynamics. Eur Phys J E Soft Matter (2013) 0.77
Multiscale modeling and simulation of microtubule-motor-protein assemblies. Phys Rev E Stat Nonlin Soft Matter Phys (2015) 0.77
Statistics of active transport in Xenopus melanophores cells. Biophys J (2010) 0.77
Origin and evolution of the self-organizing cytoskeleton in the network of eukaryotic organelles. Cold Spring Harb Perspect Biol (2014) 0.76
A journey from reductionist to systemic cell biology aboard the schooner Tara. Mol Biol Cell (2012) 0.76
Triggering signaling pathways using F-actin self-organization. Sci Rep (2016) 0.76
Self-organization in systems of treadmilling filaments. Eur Phys J E Soft Matter (2010) 0.76
Spindles and active vortices in a model of confined filament-motor mixtures. BMC Biophys (2011) 0.76
A Motor-Gradient and Clustering Model of the Centripetal Motility of MTOCs in Meiosis I of Mouse Oocytes. PLoS Comput Biol (2016) 0.75
Perspectives in active liquid crystals. Philos Trans A Math Phys Eng Sci (2014) 0.75
Embedding dual function into molecular motors through collective motion. Sci Rep (2017) 0.75
Microtubule asters as templates for nanomaterials assembly. J Biol Eng (2012) 0.75
Anaphase A: Disassembling Microtubules Move Chromosomes toward Spindle Poles. Biology (Basel) (2017) 0.75
Physical determinants of bipolar mitotic spindle assembly and stability in fission yeast. Sci Adv (2017) 0.75
A theoretical model of mitotic spindle elongation under experimental constraints. Mol Syst Biol (2008) 0.75
Molecular motors: DNA takes control. Nat Nanotechnol (2014) 0.75
Spontaneous Formation of a Globally Connected Contractile Network in a Microtubule-Motor System. Biophys J (2016) 0.75
A theory that predicts behaviors of disordered cytoskeletal networks. Mol Syst Biol (2017) 0.75
Thermodynamic Paradigm for Solution Demixing Inspired by Nuclear Transport in Living Cells. Phys Rev Lett (2017) 0.75
Mode instabilities and dynamic patterns in a colony of self-propelled surfactant particles covering a thin liquid layer. Eur Phys J E Soft Matter (2016) 0.75
Reversible and dissipative macroscopic contributions to the stress tensor: active or passive? Eur Phys J E Soft Matter (2014) 0.75
A synthetic oscillatory network of transcriptional regulators. Nature (2000) 24.58
From molecular to modular cell biology. Nature (1999) 23.51
Robustness in bacterial chemotaxis. Nature (1999) 12.55
Robustness in simple biochemical networks. Nature (1997) 12.21
Self-organization of microtubules into bipolar spindles around artificial chromosomes in Xenopus egg extracts. Nature (1996) 7.94
An ultrasensitive bacterial motor revealed by monitoring signaling proteins in single cells. Science (2000) 6.66
Protein mobility in the cytoplasm of Escherichia coli. J Bacteriol (1999) 5.94
Ran induces spindle assembly by reversing the inhibitory effect of importin alpha on TPX2 activity. Cell (2001) 5.33
Circadian clocks limited by noise. Nature (2000) 4.39
Phosphorylation and activation of human cdc25-C by cdc2--cyclin B and its involvement in the self-amplification of MPF at mitosis. EMBO J (1993) 4.33
Control of microtubule dynamics by the antagonistic activities of XMAP215 and XKCM1 in Xenopus egg extracts. Nat Cell Biol (2000) 4.31
Control of microtubule dynamics and length by cyclin A- and cyclin B-dependent kinases in Xenopus egg extracts. J Cell Biol (1992) 3.99
The subcellular organization of Madin-Darby canine kidney cells during the formation of a polarized epithelium. J Cell Biol (1989) 3.90
Generation of GTP-bound Ran by RCC1 is required for chromatin-induced mitotic spindle formation. Nature (1999) 3.84
Structure of growing microtubule ends: two-dimensional sheets close into tubes at variable rates. J Cell Biol (1995) 3.83
Self-organization of microtubules and motors. Nature (1997) 3.80
Regulation of microtubule dynamics by cdc2 protein kinase in cell-free extracts of Xenopus eggs. Nature (1990) 3.77
Ordering genes in a flagella pathway by analysis of expression kinetics from living bacteria. Science (2001) 3.69
Structural and chemical characterization of isolated centrosomes. Cell Motil Cytoskeleton (1987) 3.57
Spindle assembly in Xenopus egg extracts: respective roles of centrosomes and microtubule self-organization. J Cell Biol (1997) 3.54
A model for the proposed roles of different microtubule-based motor proteins in establishing spindle bipolarity. Curr Biol (1998) 3.42
Response regulator output in bacterial chemotaxis. EMBO J (1998) 3.40
Morphogenetic properties of microtubules and mitotic spindle assembly. Cell (1996) 3.23
cdc2 phosphorylation is required for its interaction with cyclin. EMBO J (1991) 3.22
TPX2, A novel xenopus MAP involved in spindle pole organization. J Cell Biol (2000) 3.01
Xkid, a chromokinesin required for chromosome alignment on the metaphase plate. Cell (2000) 2.90
Taxol-induced microtubule asters in mitotic extracts of Xenopus eggs: requirement for phosphorylated factors and cytoplasmic dynein. J Cell Biol (1991) 2.90
Triggering of cyclin degradation in interphase extracts of amphibian eggs by cdc2 kinase. Nature (1990) 2.89
Cdc2 H1 kinase is negatively regulated by a type 2A phosphatase in the Xenopus early embryonic cell cycle: evidence from the effects of okadaic acid. EMBO J (1990) 2.81
Interconversion of metaphase and interphase microtubule arrays, as studied by the injection of centrosomes and nuclei into Xenopus eggs. J Cell Biol (1984) 2.61
Activation of the phosphatase activity of human cdc25A by a cdk2-cyclin E dependent phosphorylation at the G1/S transition. EMBO J (1994) 2.61
Xklp1, a chromosomal Xenopus kinesin-like protein essential for spindle organization and chromosome positioning. Cell (1995) 2.57
Orientation of spindle axis and distribution of plasma membrane proteins during cell division in polarized MDCKII cells. J Cell Biol (1994) 2.44
Precise domain specification in the developing Drosophila embryo. Phys Rev E Stat Nonlin Soft Matter Phys (2005) 2.31
Lattice defects in microtubules: protofilament numbers vary within individual microtubules. J Cell Biol (1992) 2.28
Dynamic instability of microtubules as an efficient way to search in space. Proc Natl Acad Sci U S A (1994) 2.25
Control of microtubule nucleation and stability in Madin-Darby canine kidney cells: the occurrence of noncentrosomal, stable detyrosinated microtubules. J Cell Biol (1987) 2.22
Localization of the kinesin-like protein Xklp2 to spindle poles requires a leucine zipper, a microtubule-associated protein, and dynein. J Cell Biol (1998) 2.18
A post-ribosomal supernatant from activated Xenopus eggs that displays post-translationally regulated oscillation of its cdc2+ mitotic kinase activity. EMBO J (1989) 2.05
Xklp2, a novel Xenopus centrosomal kinesin-like protein required for centrosome separation during mitosis. Cell (1996) 1.97
Ran-GTP coordinates regulation of microtubule nucleation and dynamics during mitotic-spindle assembly. Nat Cell Biol (2001) 1.95
Antibodies to tubulin in normal nonimmunized animals. Proc Natl Acad Sci U S A (1977) 1.91
Dephosphorylation of cdc25-C by a type-2A protein phosphatase: specific regulation during the cell cycle in Xenopus egg extracts. Mol Biol Cell (1993) 1.87
Role of the centrosome in organizing the interphase microtubule array: properties of cytoplasts containing or lacking centrosomes. J Cell Biol (1984) 1.87
Distinct roles of PP1 and PP2A-like phosphatases in control of microtubule dynamics during mitosis. EMBO J (1997) 1.85
Geometrical aspects of the frustration in the cubic phases of lyotropic liquid crystals. Proc Natl Acad Sci U S A (1988) 1.85
Assembly and positioning of microtubule asters in microfabricated chambers. Proc Natl Acad Sci U S A (1997) 1.85
Regulation of the microtubule nucleating activity of centrosomes in Xenopus egg extracts: role of cyclin A-associated protein kinase. J Cell Biol (1992) 1.82
Reconstruction of the centrosome cycle from cryoelectron micrographs. J Struct Biol (1997) 1.71
Photoactivation turns green fluorescent protein red. Curr Biol (1997) 1.70
The stathmin/tubulin interaction in vitro. J Biol Chem (1997) 1.68
Phosphorylation changes associated with the early cell cycle in Xenopus eggs. Dev Biol (1987) 1.65
Parthenogenesis in Xenopus eggs requires centrosomal integrity. J Cell Biol (1990) 1.62
Role of xklp3, a subunit of the Xenopus kinesin II heterotrimeric complex, in membrane transport between the endoplasmic reticulum and the Golgi apparatus. J Cell Biol (1998) 1.60
Kinetics of self-assembling microtubules: an "inverse problem" in biochemistry. Proc Natl Acad Sci U S A (1996) 1.59
XMAP215 regulates microtubule dynamics through two distinct domains. EMBO J (2001) 1.57
Chromophore-assisted light inactivation and self-organization of microtubules and motors. Proc Natl Acad Sci U S A (1998) 1.55
Structural transitions at microtubule ends correlate with their dynamic properties in Xenopus egg extracts. J Cell Biol (2000) 1.51
Regulation of microtubule dynamics and nucleation during polarization in MDCK II cells. J Cell Biol (1990) 1.46
Motors involved in spindle assembly and chromosome segregation. Curr Opin Cell Biol (1996) 1.46
Chromosomes take the lead in spindle assembly. Trends Cell Biol (1995) 1.44
Mitotic chromatin regulates phosphorylation of Stathmin/Op18. Nature (1997) 1.42
Effects of brain microtubule-associated proteins on microtubule dynamics and the nucleating activity of centrosomes. Cell Motil Cytoskeleton (1990) 1.42
Cytoskeletal control of centrioles movement during the establishment of polarity in Madin-Darby canine kidney cells. J Cell Biol (1990) 1.41
Cyclin A- and cyclin B-dependent protein kinases are regulated by different mechanisms in Xenopus egg extracts. EMBO J (1992) 1.41
Movement of nuclei along microtubules in Xenopus egg extracts. Curr Biol (1997) 1.38
Role of nuclear material in the early cell cycle of Xenopus embryos. Cell (1988) 1.34
Influence of M-phase chromatin on the anisotropy of microtubule asters. J Cell Biol (1996) 1.33
An M-phase-specific protein kinase of Xenopus oocytes: partial purification and possible mechanism of its periodic activation. Dev Biol (1988) 1.32
Respective roles of centrosomes and chromatin in the conversion of microtubule arrays from interphase to metaphase. J Cell Biol (1984) 1.31
The core of the mammalian centriole contains gamma-tubulin. Curr Biol (1995) 1.25
Effect on microtubule dynamics of XMAP230, a microtubule-associated protein present in Xenopus laevis eggs and dividing cells. J Cell Biol (1994) 1.23
The role of nucleation in patterning microtubule networks. J Cell Sci (1998) 1.18
Computer simulations of self-assembled membranes. Science (1991) 1.17
Motor protein mechanics: a stochastic model with minimal mechanochemical coupling. Biophys J (1996) 1.11
Regulation of Cdc2/cyclin B activation by Ran, a Ras-related GTPase. J Cell Sci (1995) 1.08
Involvement of contractile proteins in the changes in consistency of oocyte nucleoplasm of the newt Pleurodeles waltlii. J Cell Biol (1981) 1.07
XMAP310: a Xenopus rescue-promoting factor localized to the mitotic spindle. J Cell Biol (1997) 1.04
A centrosomal antigen localized on intermediate filaments and mitotic spindle poles. J Cell Sci (1990) 0.98
Diffusion and formation of microtubule asters: physical processes versus biochemical regulation. Proc Natl Acad Sci U S A (1995) 0.98
Association of cyclin-bound p34cdc2 with subcellular structures in xenopus eggs. J Cell Sci (1992) 0.97
A protein related to brain microtubule-associated protein MAP1B is a component of the mammalian centrosome. J Cell Sci (1994) 0.97
The role of cdc25 in checkpoints and feedback controls in the eukaryotic cell cycle. J Cell Sci Suppl (1994) 0.96
Fertilization of Xenopus eggs imposes a complete translational arrest of mRNAs containing 3'UUAUUUAU elements. FEBS Lett (1994) 0.96
Regulation of protein kinases associated with cyclin A and cyclin B and their effect on microtubule dynamics and nucleation in Xenopus egg extracts. Cold Spring Harb Symp Quant Biol (1991) 0.96
Centrioles reveal their secrets. Nat Cell Biol (1999) 0.95
Regulation of p34cdc2 protein kinase: new insights into protein phosphorylation and the cell cycle. J Cell Sci (1991) 0.94
Cooperative binding of concanavalin A to thymocytes at 4 degrees C and micro-redistribution of concanavalin A receptors. Eur J Biochem (1976) 0.94
Purification of recombinant cyclin B1/cdc2 kinase from Xenopus egg extracts. Methods Enzymol (1997) 0.93
Parthenogenesis in Xenopus eggs injected with centrosomes from synchronized human lymphoid cells. Dev Biol (1989) 0.91
Detection of tubulin and actin in various cell lines by an immunoperoxidase technique. J Histochem Cytochem (1978) 0.91
S-phase induction by adenovirus E1A requires activation of cdc25a tyrosine phosphatase. Oncogene (1996) 0.89
Release of mature starfish oocytes from interphase arrest by microinjection of human centrosomes. Nature (1987) 0.88
Centrosomes competent for parthenogenesis in Xenopus eggs support procentriole budding in cell-free extracts. Proc Natl Acad Sci U S A (1991) 0.87
Cellular interactions and tubulin detyrosination in fibroblastic and epithelial cells. Biol Cell (1991) 0.86
Soluble cytokeratins in Xenopus laevis oocytes and eggs. Biol Cell (1987) 0.84
Bacterial chemotaxis. United we sense... Nature (1998) 0.84
Control of density and microredistribution of concanavalin-A receptors in rat thymocytes at 4 degrees C. Eur J Biochem (1977) 0.83
Three-dimensional reconstruction of the mammalian centriole from cryoelectron micrographs: the use of common lines for orientation and alignment. J Struct Biol (1997) 0.82