Simultaneous down-regulation of caffeic/5-hydroxy ferulic acid-O-methyltransferase I and cinnamoyl-coenzyme A reductase in the progeny from a cross between tobacco lines homozygous for each transgene. Consequences for plant development and lignin synthesis.

PubWeight™: 1.01‹?› | Rank: Top 15%

🔗 View Article (PMC 102289)

Published in Plant Physiol on May 01, 2001

Authors

G Pinçon1, M Chabannes, C Lapierre, B Pollet, K Ruel, J P Joseleau, A M Boudet, M Legrand

Author Affiliations

1: Institut de Biologie Moléculaire des Plantes du Centre National de la Recherche Scientifique, Université Louis Pasteur, 67084 Strasbourg cedex, France.

Articles citing this

Silencing of hydroxycinnamoyl-coenzyme A shikimate/quinate hydroxycinnamoyltransferase affects phenylpropanoid biosynthesis. Plant Cell (2004) 2.57

Arabidopsis fragile fiber8, which encodes a putative glucuronyltransferase, is essential for normal secondary wall synthesis. Plant Cell (2005) 2.35

Flavonoid accumulation in Arabidopsis repressed in lignin synthesis affects auxin transport and plant growth. Plant Cell (2007) 2.27

Combinatorial modification of multiple lignin traits in trees through multigene cotransformation. Proc Natl Acad Sci U S A (2003) 1.83

Downregulation of cinnamoyl-coenzyme A reductase in poplar: multiple-level phenotyping reveals effects on cell wall polymer metabolism and structure. Plant Cell (2007) 1.71

Down-regulation of the AtCCR1 gene in Arabidopsis thaliana: effects on phenotype, lignins and cell wall degradability. Planta (2003) 1.26

Simultaneous suppression of multiple genes by single transgenes. Down-regulation of three unrelated lignin biosynthetic genes in tobacco. Plant Physiol (2002) 1.05

Down-regulation of Leucaena leucocephala cinnamoyl CoA reductase (LlCCR) gene induces significant changes in phenotype, soluble phenolic pools and lignin in transgenic tobacco. Plant Cell Rep (2011) 0.87

pSAT RNA interference vectors: a modular series for multiple gene down-regulation in plants. Plant Physiol (2007) 0.84

Identification of proteins of altered abundance in oil palm infected with Ganoderma boninense. Int J Mol Sci (2014) 0.79

O-methyltransferase(s)-suppressed plants produce lower amounts of phenolic vir inducers and are less susceptible to Agrobacterium tumefaciens infection. Planta (2010) 0.77

Articles cited by this

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem (1976) 903.81

Variation in Lignin Content and Composition (Mechanisms of Control and Implications for the Genetic Improvement of Plants). Plant Physiol (1996) 3.45

Repression of lignin biosynthesis promotes cellulose accumulation and growth in transgenic trees. Nat Biotechnol (1999) 3.04

IFL1, a gene regulating interfascicular fiber differentiation in Arabidopsis, encodes a homeodomain-leucine zipper protein. Plant Cell (1999) 2.84

RECENT ADVANCES IN UNDERSTANDING LIGNIN BIOSYNTHESIS. Annu Rev Plant Physiol Plant Mol Biol (1998) 2.49

Coniferyl aldehyde 5-hydroxylation and methylation direct syringyl lignin biosynthesis in angiosperms. Proc Natl Acad Sci U S A (1999) 2.17

Dual methylation pathways in lignin biosynthesis Plant Cell (1998) 2.11

New routes for lignin biosynthesis defined by biochemical characterization of recombinant ferulate 5-hydroxylase, a multifunctional cytochrome P450-dependent monooxygenase. Proc Natl Acad Sci U S A (1999) 2.03

Reduced Lignin Content and Altered Lignin Composition in Transgenic Tobacco Down-Regulated in Expression of L-Phenylalanine Ammonia-Lyase or Cinnamate 4-Hydroxylase. Plant Physiol (1997) 1.77

Unexpected variation in lignin. Curr Opin Plant Biol (1999) 1.43

Structural Characterization of Modified Lignin in Transgenic Tobacco Plants in Which the Activity of 4-Coumarate:Coenzyme A Ligase Is Depressed. Plant Physiol (1997) 1.33

cDNA cloning, substrate specificity and expression study of tobacco caffeoyl-CoA 3-O-methyltransferase, a lignin biosynthetic enzyme. Plant Mol Biol (1998) 1.27

Tobacco O-methyltransferases involved in phenylpropanoid metabolism. The different caffeoyl-coenzyme A/5-hydroxyferuloyl-coenzyme A 3/5-O-methyltransferase and caffeic acid/5-hydroxyferulic acid 3/5-O-methyltransferase classes have distinct substrate specificities and expression patterns. Plant Physiol (1999) 1.26

NMR characterization of altered lignins extracted from tobacco plants down-regulated for lignification enzymes cinnamylalcohol dehydrogenase and cinnamoyl-CoA reductase. Proc Natl Acad Sci U S A (1998) 1.25

Study of lignification by noninvasive techniques in growing maize internodes. An investigation by Fourier transform infrared cross-polarization-magic angle spinning 13C-nuclear magnetic resonance spectroscopy and immunocytochemical transmission electron microscopy. Plant Physiol (1997) 1.23

Influence of lignin on digestibility of forage cell wall material. J Anim Sci (1986) 1.13

Plant cell walls as targets for biotechnology. Curr Opin Plant Biol (1998) 1.02

Articles by these authors

Biological function of ;pathogenesis-related' proteins: four PR proteins of tobacco have 1,3-beta-glucanase activity. EMBO J (1987) 4.82

Metabolic and respiratory changes after cholecystectomy performed via laparotomy or laparoscopy. Br J Anaesth (1992) 3.50

Plant 'pathogenesis-related' proteins and their role in defense against pathogens. Biochimie (1993) 2.57

Soft-tissue venous malformations in adult patients: imaging and therapeutic issues. Radiographics (2001) 2.34

Cinnamyl-alcohol dehydrogenase, a molecular marker specific for lignin synthesis: cDNA cloning and mRNA induction by fungal elicitor. Proc Natl Acad Sci U S A (1988) 2.03

Strong decrease in lignin content without significant alteration of plant development is induced by simultaneous down-regulation of cinnamoyl CoA reductase (CCR) and cinnamyl alcohol dehydrogenase (CAD) in tobacco plants. Plant J (2001) 1.90

Molecular cloning and expression of a Eucalyptus gunnii cDNA clone encoding cinnamyl alcohol dehydrogenase. Plant Mol Biol (1993) 1.81

Pathogenesis-related PR-1 proteins are antifungal. Isolation and characterization of three 14-kilodalton proteins of tomato and of a basic PR-1 of tobacco with inhibitory activity against Phytophthora infestans. Plant Physiol (1995) 1.79

Regulation of enzymes involved in lignin biosynthesis: induction of O-methyltransferase mRNAs during the hypersensitive reaction of tobacco to tobacco mosaic virus. Mol Plant Microbe Interact (1992) 1.77

Purification and properties of cinnamoyl-CoA reductase and cinnamyl alcohol dehydrogenase from poplar stems (Populus X euramericana). Eur J Biochem (1984) 1.72

Laparoscopic repair of perforated duodenal ulcer. A prospective multicenter clinical trial. Surg Endosc (1997) 1.71

Activation of plant quinate:NAD 3-oxidoreductase by Ca and calmodulin. Proc Natl Acad Sci U S A (1983) 1.70

Laparoscopic liver resection of benign liver tumors. Surg Endosc (2002) 1.68

Cinnamoyl CoA reductase, the first committed enzyme of the lignin branch biosynthetic pathway: cloning, expression and phylogenetic relationships. Plant J (1997) 1.64

Modifications in lignin and accumulation of phenolic glucosides in poplar xylem upon down-regulation of caffeoyl-coenzyme A O-methyltransferase, an enzyme involved in lignin biosynthesis. J Biol Chem (2000) 1.58

Molecular cloning and expression of a new class of ortho-diphenol-O-methyltransferases induced in tobacco (Nicotiana tabacum L.) leaves by infection or elicitor treatment. Plant Physiol (1993) 1.57

Involvement of an Extracellular Glucan Sheath during Degradation of Populus Wood by Phanerochaete chrysosporium. Appl Environ Microbiol (1991) 1.57

Polymorphism of the cytochrome P450 CYP2D6 gene in a European population: characterization of 48 mutations and 53 alleles, their frequencies and evolution. Pharmacogenetics (1997) 1.55

Extensive sequence similarity of the bean CAD4 (cinnamyl-alcohol dehydrogenase) to a maize malic enzyme. Plant Mol Biol (1990) 1.52

Coarctation of the aorta: pre and postoperative evaluation with MRI and MR angiography; correlation with echocardiography and surgery. Int J Cardiovasc Imaging (2005) 1.51

Laparoscopic adjustable gastric banding. World J Surg (1998) 1.48

Changes in phenylalanine ammonia-lyase during the hypersensitive reaction of tobacco to TMV. Virology (1973) 1.48

Nucleotide sequence of a complementary DNA encoding o-methyltransferase from poplar. Plant Physiol (1992) 1.44

Acute respiratory failure in neutropenic patients is associated with a high post-ICU mortality. Minerva Anestesiol (2013) 1.41

Laparoscopic treatment of nonparasitic liver cysts: adequate selection of patients and surgical technique. World J Surg (1996) 1.41

Elucidation of new structures in lignins of CAD- and COMT-deficient plants by NMR. Phytochemistry (2001) 1.37

Fourier-transform infrared and Raman spectroscopic evidence for the incorporation of cinnamaldehydes into the lignin of transgenic tobacco (Nicotiana tabacum L.) plants with reduced expression of cinnamyl alcohol dehydrogenase. Planta (1997) 1.36

Immunogold localization of beta-1,3-glucanases in two plants infected by vascular wilt fungi. Plant Cell (1989) 1.35

The dramatic reality of biliary tract injury during laparoscopic cholecystectomy. An anonymous multicenter Belgian survey of 65 patients. Surg Endosc (1997) 1.35

Phenylalanine ammonia-lyase in tobacco. Molecular cloning and gene expression during the hypersensitive reaction to tobacco mosaic virus and the response to a fungal elicitor. Plant Physiol (1994) 1.32

Chemical analysis and immunolocalisation of lignin and suberin in endodermal and hypodermal/rhizodermal cell walls of developing maize (Zea mays L.) primary roots. Planta (1999) 1.31

Lignification in transgenic poplars with extremely reduced caffeic acid O-methyltransferase activity. Plant Physiol (2000) 1.30

Phenolic metabolism in petunia tissues. IV. - Properties of p-coumarate : coenzyme A ligase isoenzymes. Biochimie (1976) 1.30

Repression of O-methyltransferase genes in transgenic tobacco affects lignin synthesis and plant growth. Phytochemistry (2001) 1.28

Ultrastructural study of pleural fluid in mesothelioma. Thorax (1974) 1.28

cDNA cloning, substrate specificity and expression study of tobacco caffeoyl-CoA 3-O-methyltransferase, a lignin biosynthetic enzyme. Plant Mol Biol (1998) 1.27

Redox Processes in the Blue Light Response of Guard Cell Protoplasts of Commelina communis L. Plant Physiol (1992) 1.27

Tobacco Mesophyll Protoplasts Synthesize 1,3-beta-Glucanase, Chitinases, and "Osmotins" during in Vitro Culture. Plant Physiol (1990) 1.27

Tobacco O-methyltransferases involved in phenylpropanoid metabolism. The different caffeoyl-coenzyme A/5-hydroxyferuloyl-coenzyme A 3/5-O-methyltransferase and caffeic acid/5-hydroxyferulic acid 3/5-O-methyltransferase classes have distinct substrate specificities and expression patterns. Plant Physiol (1999) 1.26

NMR characterization of altered lignins extracted from tobacco plants down-regulated for lignification enzymes cinnamylalcohol dehydrogenase and cinnamoyl-CoA reductase. Proc Natl Acad Sci U S A (1998) 1.25

Use of enzyme-gold complexes for the ultrastructural localization of hemicelluloses in the plant cell wall. Histochemistry (1984) 1.24

Hydrolysis of Intracellular Proteins in Vacuoles Isolated from Acer pseudoplatanus L. Cells. Plant Physiol (1985) 1.23

Study of lignification by noninvasive techniques in growing maize internodes. An investigation by Fourier transform infrared cross-polarization-magic angle spinning 13C-nuclear magnetic resonance spectroscopy and immunocytochemical transmission electron microscopy. Plant Physiol (1997) 1.23

Antimicrobial proteins in induced plant defense. Curr Opin Immunol (1998) 1.22

Polymeric proanthocyanidins are catabolized by human colonic microflora into low-molecular-weight phenolic acids. J Nutr (2000) 1.21

Substrate specificities of tobacco chitinases. Plant J (1998) 1.21

In situ analysis of lignins in transgenic tobacco reveals a differential impact of individual transformations on the spatial patterns of lignin deposition at the cellular and subcellular levels. Plant J (2001) 1.19

Enzymatic synthesis of lignin: purification to homogeneity of the three O-methyltransferases of tobacco and production of specific antibodies. Arch Biochem Biophys (1987) 1.19

Plasma membrane vesicles of opposite sidedness from soybean hypocotyls by preparative free-flow electrophoresis. Plant Physiol (1988) 1.15

NMR evidence for benzodioxane structures resulting from incorporation of 5-hydroxyconiferyl alcohol into Lignins of O-methyltransferase-deficient poplars. J Agric Food Chem (2001) 1.14

Structure of the Primary Cell Walls of Suspension-Cultured Rosa glauca Cells: I. Polysaccharides Associated with Cellulose. Plant Physiol (1984) 1.12

[Ultrastructure of the human parietal pleura]. Presse Med (1971) 1.10

Rapid Degradation of Abnormal Proteins in Vacuoles from Acer pseudoplatanus L. Cells. Plant Physiol (1986) 1.09

Determination of twelve antiretroviral agents in human plasma sample using reversed-phase high-performance liquid chromatography. J Chromatogr B Biomed Sci Appl (2000) 1.09

Cloning and characterization of two maize cDNAs encoding cinnamoyl-CoA reductase (CCR) and differential expression of the corresponding genes. Plant Mol Biol (1998) 1.09

Biochemical characterization, molecular cloning and expression of laccases - a divergent gene family - in poplar. Eur J Biochem (1999) 1.09

A family of Arabidopsis plasma membrane receptors presenting animal beta-integrin domains. Biochim Biophys Acta (1999) 1.08

Characterization of cis-elements required for vascular expression of the cinnamoyl CoA reductase gene and for protein-DNA complex formation. Plant J (2000) 1.07

Isolation and characterization of a proteinaceous inhibitor of microbial proteinases induced during the hypersensitive reaction of tobacco to tobacco mosaic virus. Mol Plant Microbe Interact (1992) 1.06

Subcellular Localization of 2-(beta-d-Glucosyloxy)-Cinnamic Acids and the Related beta-glucosidase in Leaves of Melilotus alba Desr. Plant Physiol (1981) 1.05

A novel aromatic alcohol dehydrogenase in higher plants: molecular cloning and expression. Plant Mol Biol (1998) 1.02

Calcifying fibrous tumour of the gastric wall. Histopathology (2004) 1.00

Pseudotumoral lymphocytic hypophysitis successfully treated by corticosteroid alone: first case report. Neurosurgery (1994) 0.99

Structural cell-wall proteins in protoxylem development: evidence for a repair process mediated by a glycine-rich protein. Plant J (1997) 0.99

Soluble phospholipase A2 activity is induced before oxylipin accumulation in tobacco mosaic virus-infected tobacco leaves and is contributed by patatin-like enzymes. Plant J (2000) 0.98

Pharmacokinetic of nevirapine in haemodialysis. Nephrol Dial Transplant (2001) 0.98

A fucoidan fraction from Ascophyllum nodosum. Carbohydr Res (2001) 0.97

Purification and characterization of isoforms of cinnamyl alcohol dehydrogenase from Eucalyptus xylem. Planta (1992) 0.96

Identification of the enzymatic active site of tobacco caffeoyl-coenzyme A O-methyltransferase by site-directed mutagenesis. J Biol Chem (2001) 0.96

Nitric oxide co-operates with hydrogen peroxide in inducing DNA fragmentation and cell lysis in murine lymphoma cells. Biochem J (1997) 0.94

A novel CYP2D6 allele with an abolished splice recognition site associated with the poor metabolizer phenotype. Pharmacogenetics (1995) 0.93

Nutritional assessment in Duchenne muscular dystrophy. Dev Med Child Neurol (1993) 0.93

A molecular model for cinnamyl alcohol dehydrogenase, a plant aromatic alcohol dehydrogenase involved in lignification. Biochim Biophys Acta (1993) 0.93

Isolation and characterization of six pathogenesis-related (PR) proteins of Samsun NN tobacco. Plant Mol Biol (1990) 0.92

Population pharmacokinetic analysis for nelfinavir and its metabolite M8 in virologically controlled HIV-infected patients on HAART. Br J Clin Pharmacol (2005) 0.92

Characterization of palo podrido, a natural process of delignification in wood. Appl Environ Microbiol (1990) 0.91

A cDNA encoding S-adenosyl-L-methionine:caffeic acid 3-O-methyltransferase from Eucalyptus. Plant Physiol (1994) 0.91

Structure of the capsular polysaccharide of Klebsiella K-type 63. Carbohydr Res (1979) 0.91

The development and evaluation of ultrasound in the biocidal treatment of water. Ultrason Sonochem (1997) 0.91

Molecular characterization of a novel tobacco pathogenesis-related (PR) protein: a new plant chitinase/lysozyme. Mol Gen Genet (1994) 0.91

Introduction of specific carbohydrates into Eucalyptus gunnii cells increases their freezing tolerance. Eur J Biochem (1995) 0.91

Antitumor active beta-D-glucans from Phytophthora parasitica. Carbohydr Res (1988) 0.91

Site-directed mutagenesis of a serine residue in cinnamyl alcohol dehydrogenase, a plant NADPH-dependent dehydrogenase, affects the specificity for the coenzyme. Biochemistry (1995) 0.89

cDNA cloning and gene expression analysis of the microbial proteinase inhibitor of tobacco. J Biol Chem (1993) 0.89

One-step purification and characterization of a lignin-specific O-methyltransferase from poplar. Gene (1993) 0.88

Callus formation and induction of a cell suspension culture from Acacia senegal. Plant Cell Rep (1986) 0.88

Isoenzymes of hydroxycinnamate: CoA ligase from poplar stems properties and tissue distribution. Planta (1983) 0.88

Reassessment of qualitative changes in lignification of transgenic tobacco plants and their impact on cell wall assembly. Phytochemistry (2001) 0.87

Phenolic metabolism in petunia tissues. I. Characteristic responses of enzymes involved in different steps of polyphenol synthesis to different hormonal influences. Biochim Biophys Acta (1975) 0.87

Blockade of cytotoxic T-lymphocyte antigen-4 by ipilimumab is associated with a profound long-lasting depletion of Foxp3+ regulatory T cells: a mechanistic explanation for ipilimumab-induced severe enterocolitis? Inflamm Bowel Dis (2011) 0.86