Cinnamoyl CoA reductase, the first committed enzyme of the lignin branch biosynthetic pathway: cloning, expression and phylogenetic relationships.

PubWeight™: 1.64‹?› | Rank: Top 3%

🔗 View Article (PMID 9107033)

Published in Plant J on March 01, 1997

Authors

E Lacombe1, S Hawkins, J Van Doorsselaere, J Piquemal, D Goffner, O Poeydomenge, A M Boudet, J Grima-Pettenati

Author Affiliations

1: UMR CNRS-UPS No. 5546, Centre de Physiologie Végétale, Université Paul Sabatier, Toulouse, France.

Articles citing this

Coniferyl aldehyde 5-hydroxylation and methylation direct syringyl lignin biosynthesis in angiosperms. Proc Natl Acad Sci U S A (1999) 2.17

Cinnamoyl-CoA reductase, a key enzyme in lignin biosynthesis, is an effector of small GTPase Rac in defense signaling in rice. Proc Natl Acad Sci U S A (2005) 1.75

The last step of syringyl monolignol biosynthesis in angiosperms is regulated by a novel gene encoding sinapyl alcohol dehydrogenase. Plant Cell (2001) 1.73

Downregulation of cinnamoyl-coenzyme A reductase in poplar: multiple-level phenotyping reveals effects on cell wall polymer metabolism and structure. Plant Cell (2007) 1.71

Polymorphisms in cinnamoyl CoA reductase (CCR) are associated with variation in microfibril angle in Eucalyptus spp. Genetics (2005) 1.49

Redirection of the phenylpropanoid pathway to feruloyl malate in Arabidopsis mutants deficient for cinnamoyl-CoA reductase 1. Planta (2007) 1.45

Stress-induced protein S-glutathionylation in Arabidopsis. Plant Physiol (2005) 1.37

The phenylpropanoid pathway in Arabidopsis. Arabidopsis Book (2011) 1.27

Down-regulation of the AtCCR1 gene in Arabidopsis thaliana: effects on phenotype, lignins and cell wall degradability. Planta (2003) 1.26

Functional analyses of caffeic acid O-Methyltransferase and Cinnamoyl-CoA-reductase genes from perennial ryegrass (Lolium perenne). Plant Cell (2010) 1.24

Analysis of TETRAKETIDE α-PYRONE REDUCTASE function in Arabidopsis thaliana reveals a previously unknown, but conserved, biochemical pathway in sporopollenin monomer biosynthesis. Plant Cell (2010) 1.23

Distinct cinnamoyl CoA reductases involved in parallel routes to lignin in Medicago truncatula. Proc Natl Acad Sci U S A (2010) 1.18

Characterization of a cinnamoyl-CoA reductase 1 (CCR1) mutant in maize: effects on lignification, fibre development, and global gene expression. J Exp Bot (2011) 1.03

The cell biology of lignification in higher plants. Ann Bot (2015) 1.02

Ancient origin of the biosynthesis of lignin precursors. Biol Direct (2015) 0.97

The plant short-chain dehydrogenase (SDR) superfamily: genome-wide inventory and diversification patterns. BMC Plant Biol (2012) 0.96

Functional characterization of Dihydroflavonol-4-reductase in anthocyanin biosynthesis of purple sweet potato underlies the direct evidence of anthocyanins function against abiotic stresses. PLoS One (2013) 0.96

A fruit-specific putative dihydroflavonol 4-reductase gene is differentially expressed in strawberry during the ripening process. Plant Physiol (1998) 0.95

Rice Snl6, a cinnamoyl-CoA reductase-like gene family member, is required for NH1-mediated immunity to Xanthomonas oryzae pv. oryzae. PLoS Genet (2010) 0.95

A new genomic resource dedicated to wood formation in Eucalyptus. BMC Plant Biol (2009) 0.94

Molecular cloning and characterization of two genes encoding dihydroflavonol-4-reductase from Populus trichocarpa. PLoS One (2012) 0.91

Comprehensive genetic dissection of wood properties in a widely-grown tropical tree: Eucalyptus. BMC Genomics (2011) 0.88

Ectopic lignification in the flax lignified bast fiber1 mutant stem is associated with tissue-specific modifications in gene expression and cell wall composition. Plant Cell (2014) 0.87

Down-regulation of Leucaena leucocephala cinnamoyl CoA reductase (LlCCR) gene induces significant changes in phenotype, soluble phenolic pools and lignin in transgenic tobacco. Plant Cell Rep (2011) 0.87

Advancing Eucalyptus genomics: identification and sequencing of lignin biosynthesis genes from deep-coverage BAC libraries. BMC Genomics (2011) 0.85

Structural and docking studies of Leucaena leucocephala Cinnamoyl CoA reductase. J Mol Model (2010) 0.83

Identification of gene-specific polymorphisms and association with capsaicin pathway metabolites in Capsicum annuum L. collections. PLoS One (2014) 0.82

Reduced lignin content and altered lignin composition in the warm season forage grass Paspalum dilatatum by down-regulation of a Cinnamoyl CoA reductase gene. Transgenic Res (2014) 0.82

Allelic variation of soybean flower color gene W4 encoding dihydroflavonol 4-reductase 2. BMC Plant Biol (2014) 0.81

FaPOD27 functions in the metabolism of polyphenols in strawberry fruit (Fragaria sp.). Front Plant Sci (2014) 0.81

Coordinated transcriptional regulation of two key genes in the lignin branch pathway--CAD and CCR--is mediated through MYB- binding sites. BMC Plant Biol (2010) 0.80

Identification of quantitative trait loci controlling fibre length and lignin content in Arabidopsis thaliana stems. J Exp Bot (2012) 0.80

Beta hydroxylation of glycolipids from Ustilago maydis and Pseudozyma flocculosa by an NADPH-dependent β-hydroxylase. Appl Environ Microbiol (2011) 0.79

Frequency-based time-series gene expression recomposition using PRIISM. BMC Syst Biol (2012) 0.79

RNA-Seq Based De Novo Transcriptome Assembly and Gene Discovery of Cistanche deserticola Fleshy Stem. PLoS One (2015) 0.78

Characterization of the cinnamoyl-CoA reductase (CCR) gene family in Populus tomentosa reveals the enzymatic active sites and evolution of CCR. Planta (2016) 0.77

Advancing Eucalyptus Genomics: Cytogenomics Reveals Conservation of Eucalyptus Genomes. Front Plant Sci (2016) 0.76

Cloning and expression analysis of cinnamoyl-CoA reductase (CCR) genes in sorghum. PeerJ (2016) 0.75

Dihydroflavonol 4-Reductase Genes from Freesia hybrida Play Important and Partially Overlapping Roles in the Biosynthesis of Flavonoids. Front Plant Sci (2017) 0.75

Cloning, overexpression, and mutagenesis of the Sporobolomyces salmonicolor AKU4429 gene encoding a new aldehyde reductase, which catalyzes the stereoselective reduction of ethyl 4-chloro-3-oxobutanoate to ethyl (S)-4-chloro-3-hydroxybutanoate. Appl Environ Microbiol (1999) 0.75

in Silico mutagenesis and docking studies of active site residues suggest altered substrate specificity and possible physiological role of Cinnamoyl CoA Reductase 1 (Ll-CCRH1). Bioinformation (2013) 0.75

Transcriptome Analysis of an Anthracnose-Resistant Tea Plant Cultivar Reveals Genes Associated with Resistance to Colletotrichum camelliae. PLoS One (2016) 0.75

Flavonoid supplementation affects the expression of genes involved in cell wall formation and lignification metabolism and increases sugar content and saccharification in the fast-growing eucalyptus hybrid E. urophylla x E. grandis. BMC Plant Biol (2014) 0.75

Structural and Biochemical Characterization of Cinnamoyl-CoA Reductases. Plant Physiol (2016) 0.75

Spatial regulation of monolignol biosynthesis and laccase genes control developmental and stress-related lignin in flax. BMC Plant Biol (2017) 0.75

Articles by these authors

Homeopathic arnica for prevention of pain and bruising: randomized placebo-controlled trial in hand surgery. J R Soc Med (2003) 3.92

Multiple Sclerosis Severity Score: using disability and disease duration to rate disease severity. Neurology (2005) 3.45

Cinnamyl-alcohol dehydrogenase, a molecular marker specific for lignin synthesis: cDNA cloning and mRNA induction by fungal elicitor. Proc Natl Acad Sci U S A (1988) 2.03

Strong decrease in lignin content without significant alteration of plant development is induced by simultaneous down-regulation of cinnamoyl CoA reductase (CCR) and cinnamyl alcohol dehydrogenase (CAD) in tobacco plants. Plant J (2001) 1.90

Molecular cloning and expression of a Eucalyptus gunnii cDNA clone encoding cinnamyl alcohol dehydrogenase. Plant Mol Biol (1993) 1.81

Purification and properties of cinnamoyl-CoA reductase and cinnamyl alcohol dehydrogenase from poplar stems (Populus X euramericana). Eur J Biochem (1984) 1.72

Activation of plant quinate:NAD 3-oxidoreductase by Ca and calmodulin. Proc Natl Acad Sci U S A (1983) 1.70

Tissue- and cell-specific expression of a cinnamyl alcohol dehydrogenase promoter in transgenic poplar plants. Plant Mol Biol (1995) 1.68

Increased incidence of intraventricular hemorrhage and developmental delay in cocaine-exposed, very low birth weight infants. J Pediatr (1994) 1.59

Extensive sequence similarity of the bean CAD4 (cinnamyl-alcohol dehydrogenase) to a maize malic enzyme. Plant Mol Biol (1990) 1.52

Succinylcholine-assisted intubations in prehospital care. Ann Emerg Med (1988) 1.44

Nucleotide sequence of a complementary DNA encoding o-methyltransferase from poplar. Plant Physiol (1992) 1.44

Two cinnamoyl-CoA reductase (CCR) genes from Arabidopsis thaliana are differentially expressed during development and in response to infection with pathogenic bacteria. Phytochemistry (2001) 1.38

Elucidation of new structures in lignins of CAD- and COMT-deficient plants by NMR. Phytochemistry (2001) 1.37

Fourier-transform infrared and Raman spectroscopic evidence for the incorporation of cinnamaldehydes into the lignin of transgenic tobacco (Nicotiana tabacum L.) plants with reduced expression of cinnamyl alcohol dehydrogenase. Planta (1997) 1.36

Job-based health insurance in 2001: inflation hits double digits, managed care retreats. Health Aff (Millwood) (2001) 1.32

Changes in the male voice at puberty: vocal fold length and its relationship to the fundamental frequency of the voice. J Laryngol Otol (1998) 1.31

Phenolic metabolism in petunia tissues. IV. - Properties of p-coumarate : coenzyme A ligase isoenzymes. Biochimie (1976) 1.30

Changes in the male voice at puberty. Arch Dis Child (1997) 1.27

Redox Processes in the Blue Light Response of Guard Cell Protoplasts of Commelina communis L. Plant Physiol (1992) 1.27

NMR characterization of altered lignins extracted from tobacco plants down-regulated for lignification enzymes cinnamylalcohol dehydrogenase and cinnamoyl-CoA reductase. Proc Natl Acad Sci U S A (1998) 1.25

Hydrolysis of Intracellular Proteins in Vacuoles Isolated from Acer pseudoplatanus L. Cells. Plant Physiol (1985) 1.23

In situ analysis of lignins in transgenic tobacco reveals a differential impact of individual transformations on the spatial patterns of lignin deposition at the cellular and subcellular levels. Plant J (2001) 1.19

Job-based health insurance in 2000: premiums rise sharply while coverage grows. Health Aff (Millwood) (2000) 1.16

Plasma membrane vesicles of opposite sidedness from soybean hypocotyls by preparative free-flow electrophoresis. Plant Physiol (1988) 1.15

NMR evidence for benzodioxane structures resulting from incorporation of 5-hydroxyconiferyl alcohol into Lignins of O-methyltransferase-deficient poplars. J Agric Food Chem (2001) 1.14

Screening slaughtered cattle for BSE. Nature (2001) 1.09

Cloning and characterization of two maize cDNAs encoding cinnamoyl-CoA reductase (CCR) and differential expression of the corresponding genes. Plant Mol Biol (1998) 1.09

Rapid Degradation of Abnormal Proteins in Vacuoles from Acer pseudoplatanus L. Cells. Plant Physiol (1986) 1.09

Biochemical characterization, molecular cloning and expression of laccases - a divergent gene family - in poplar. Eur J Biochem (1999) 1.09

Characterization of cis-elements required for vascular expression of the cinnamoyl CoA reductase gene and for protein-DNA complex formation. Plant J (2000) 1.07

Subcellular Localization of 2-(beta-d-Glucosyloxy)-Cinnamic Acids and the Related beta-glucosidase in Leaves of Melilotus alba Desr. Plant Physiol (1981) 1.05

Purification and characterization of cinnamyl alcohol dehydrogenase from tobacco stems. Plant Physiol (1992) 1.04

A novel aromatic alcohol dehydrogenase in higher plants: molecular cloning and expression. Plant Mol Biol (1998) 1.02

Simultaneous down-regulation of caffeic/5-hydroxy ferulic acid-O-methyltransferase I and cinnamoyl-coenzyme A reductase in the progeny from a cross between tobacco lines homozygous for each transgene. Consequences for plant development and lignin synthesis. Plant Physiol (2001) 1.01

A compact linac for intensity modulated proton therapy based on a dielectric wall accelerator. Phys Med (2008) 1.00

Differential accumulation of monolignol-derived compounds in elicited flax (Linum usitatissimum) cell suspension cultures. Planta (2005) 0.99

Partial purification and identification of GDP-mannose 3",5"-epimerase of Arabidopsis thaliana, a key enzyme of the plant vitamin C pathway. Proc Natl Acad Sci U S A (2001) 0.99

ESTs from the fibre-bearing stem tissues of flax (Linum usitatissimum L.): expression analyses of sequences related to cell wall development. Plant Biol (Stuttg) (2005) 0.98

Purification and characterization of isoforms of cinnamyl alcohol dehydrogenase from Eucalyptus xylem. Planta (1992) 0.96

The Siva-1 putative amphipathic helical region (SAH) is sufficient to bind to BCL-XL and sensitize cells to UV radiation induced apoptosis. Apoptosis (2004) 0.96

Siva-1 negatively regulates NF-kappaB activity: effect on T-cell receptor-mediated activation-induced cell death (AICD). Oncogene (2006) 0.96

Antigenic differences among porcine circovirus type 2 strains, as demonstrated by the use of monoclonal antibodies. J Gen Virol (2008) 0.95

Very-low-birthweight children and speech and language development. J Speech Hear Res (1991) 0.94

Catalytic site of calmodulin-dependent protein phosphatase from bovine brain resides in subunit A. Proc Natl Acad Sci U S A (1984) 0.93

A molecular model for cinnamyl alcohol dehydrogenase, a plant aromatic alcohol dehydrogenase involved in lignification. Biochim Biophys Acta (1993) 0.93

Feeding interactions in infants with very low birth weight and bronchopulmonary dysplasia. J Dev Behav Pediatr (1996) 0.92

A cDNA encoding S-adenosyl-L-methionine:caffeic acid 3-O-methyltransferase from Eucalyptus. Plant Physiol (1994) 0.91

Introduction of specific carbohydrates into Eucalyptus gunnii cells increases their freezing tolerance. Eur J Biochem (1995) 0.91

Vocal function following radiation for non-laryngeal versus laryngeal tumors of the head and neck. Laryngoscope (2001) 0.91

A primary care-based needs assessment of people with multiple sclerosis. Br J Gen Pract (2005) 0.90

The influence of spectral prominence on perceived vowel quality. J Acoust Soc Am (1990) 0.90

The MHC2TA-168A/G and +1614G/C polymorphisms and risk for multiple sclerosis or chronic inflammatory arthropathies. Tissue Antigens (2007) 0.89

Immunolocalization of cinnamyl alcohol dehydrogenase 2 (CAD 2) indicates a good correlation with cell-specific activity of CAD 2 promoter in transgenic poplar shoots. Planta (1998) 0.89

Genetic characterization of African swine fever viruses from a 2008 outbreak in Tanzania. Transbound Emerg Dis (2010) 0.89

Preschool language outcomes of children with history of bronchopulmonary dysplasia and very low birth weight. J Dev Behav Pediatr (2001) 0.89

Site-directed mutagenesis of a serine residue in cinnamyl alcohol dehydrogenase, a plant NADPH-dependent dehydrogenase, affects the specificity for the coenzyme. Biochemistry (1995) 0.89

Isoenzymes of hydroxycinnamate: CoA ligase from poplar stems properties and tissue distribution. Planta (1983) 0.88

Loss of expression of the beta subunit of soluble guanylyl cyclase prevents nitric oxide-mediated inhibition of DNA synthesis in smooth muscle cells of old rats. Circ Res (2000) 0.87

Phenolic metabolism in petunia tissues. I. Characteristic responses of enzymes involved in different steps of polyphenol synthesis to different hormonal influences. Biochim Biophys Acta (1975) 0.87

Efficacy of commercial swine influenza vaccines against challenge with a recent European H1N1 field isolate. Vet Microbiol (2010) 0.87

Kinetic and inhibition studies of cinnamoyl-CoA reductase 1 from Arabidopsis thaliana. Plant Physiol Biochem (2005) 0.87

Characterization of chilling-acclimation-related proteins in soybean and identification of one as a member of the heat shock protein (HSP 70) family. Planta (1993) 0.86

Developmental outcomes and environmental correlates of very low birthweight, cocaine-exposed infants. Early Hum Dev (2001) 0.86

Purification and characterization of cinnamyl alcohol dehydrogenase isoforms from Phaseolus vulgaris. Phytochemistry (1994) 0.86

Polymorphisms in the interleukin-4 and IL-4 receptor genes and multiple sclerosis: a study in Spanish-Basque, Northern Irish and Belgian populations. Int J Immunogenet (2005) 0.86

Lateral and Rotational Mobilities of Lipids in Specific Cellular Membranes of Eucalyptus gunnii Cultivars Exhibiting Different Freezing Tolerance. Plant Physiol (1992) 0.85

Tonoplast vesicles of opposite sidedness from soybean hypocotyls by preparative free-flow electrophoresis. Plant Physiol (1990) 0.85

Nucleotide sequence of a cDNA encoding cinnamyl alcohol dehydrogenase from Eucalyptus. Plant Physiol (1993) 0.85

Tail-gut cyst. Australas Radiol (1997) 0.85

The impact of heart health promotion on coronary heart disease lifestyle risk factors in schoolchildren: lessons learnt from a community-based project. Public Health (1997) 0.85

Partial genetic characterization of peste des petits ruminants virus from goats in northern and eastern Tanzania. Transbound Emerg Dis (2014) 0.84

Eucalyptus gunnii CCR and CAD2 promoters are active in lignifying cells during primary and secondary xylem formation in Arabidopsis thaliana. Plant Physiol Biochem (2006) 0.84

Overexpression of CCAAT displacement protein represses the promiscuously active proximal gp91(phox) promoter. Blood (1999) 0.83

Evidence for the involvement of activated oxygen in fungal degradation of lignocellulose. Biochimie (1983) 0.83

Recombination of two porcine circovirus type 2 strains. Arch Virol (2009) 0.83

Cross-coupling of hydroxycinnamyl aldehydes into lignins. Org Lett (2000) 0.83

HLA-DR and DQ DNA genotyping in multiple sclerosis patients in Northern Ireland. Hum Immunol (1991) 0.82

Effects of head and neck radiation therapy on vocal function. J Otolaryngol (2001) 0.82