Published in J Biol Chem on February 28, 2001
Natural-product sugar biosynthesis and enzymatic glycodiversification. Angew Chem Int Ed Engl (2008) 2.69
Identification and manipulation of the caprazamycin gene cluster lead to new simplified liponucleoside antibiotics and give insights into the biosynthetic pathway. J Biol Chem (2009) 1.26
Biosynthesis of spinosyn in Saccharopolyspora spinosa: synthesis of permethylated rhamnose and characterization of the functions of SpnH, SpnI, and SpnK. J Am Chem Soc (2010) 1.21
Combinatorial biosynthesis of antitumor deoxysugar pathways in Streptomyces griseus: Reconstitution of "unnatural natural gene clusters" for the biosynthesis of four 2,6-D-dideoxyhexoses. Appl Environ Microbiol (2006) 0.98
Methylation of GPLs in Mycobacterium smegmatis and Mycobacterium avium. J Bacteriol (2004) 0.95
Functional analysis of MycE and MycF, two O-methyltransferases involved in the biosynthesis of mycinamicin macrolide antibiotics. Chembiochem (2009) 0.92
SpnH from Saccharopolyspora spinosa encodes a rhamnosyl 4'-O-methyltransferase for biosynthesis of the insecticidal macrolide, spinosyn A. J Ind Microbiol Biotechnol (2008) 0.87
Analysis of an 8.1-kb DNA fragment contiguous with the erythromycin gene cluster of Saccharopolyspora erythraea in the eryCI-flanking region. Antimicrob Agents Chemother (2002) 0.83
A new structural form in the SAM/metal-dependent o‑methyltransferase family: MycE from the mycinamicin biosynthetic pathway. J Mol Biol (2011) 0.83
Structural and functional characterization of CalS11, a TDP-rhamnose 3'-O-methyltransferase involved in calicheamicin biosynthesis. ACS Chem Biol (2013) 0.82
Functional characterisation of three o-methyltransferases involved in the biosynthesis of phenolglycolipids in Mycobacterium tuberculosis. PLoS One (2013) 0.78
Formation and attachment of the deoxysugar moiety and assembly of the gene cluster for caprazamycin biosynthesis. Appl Environ Microbiol (2010) 0.77
Genome mining of the sordarin biosynthetic gene cluster from Sordaria araneosa Cain ATCC 36386: characterization of cycloaraneosene synthase and GDP-6-deoxyaltrose transferase. J Antibiot (Tokyo) (2016) 0.75
Enzymatic methylation and structure-activity-relationship studies on polycarcin V, a gilvocarcin-type antitumor agent. Chembiochem (2014) 0.75
Structural basis of substrate specificity and regiochemistry in the MycF/TylF family of sugar O-methyltransferases. ACS Chem Biol (2015) 0.75
Estimate of human gene number provided by genome-wide analysis using Tetraodon nigroviridis DNA sequence. Nat Genet (2000) 14.51
Haplotype sharing analysis using mantel statistics. Hum Hered (2005) 6.76
Miltefosine, an oral agent, for the treatment of Indian visceral leishmaniasis. N Engl J Med (1999) 5.02
Alternative polyadenylation events contribute to the induction of NF-ATc in effector T cells. Immunity (1999) 3.69
Small-bowel diverticulosis: perceptions and reality. J Am Coll Surg (1997) 3.09
Non-random radial higher-order chromatin arrangements in nuclei of diploid human cells. Chromosome Res (2001) 2.89
The Ets-1 transcription factor is required for the development of natural killer cells in mice. Immunity (1998) 2.68
Therapeutic efficacy of sulfasalazine and its metabolites in patients with ulcerative colitis and Crohn's disease. N Engl J Med (1980) 2.39
Hearing preservation in acoustic neurinoma surgery. J Neurosurg (1992) 2.33
Renal ischemia/reperfusion leads to macrophage-mediated increase in pulmonary vascular permeability. Kidney Int (1999) 2.17
Oscillatory synchrony between human extrastriate areas during visual short-term memory maintenance. J Neurosci (2001) 2.08
[Human ecology: a judicial statute of the human body]. Med Clin (Barc) (1995) 1.96
Neuromonitoring during surgery. Report of an IFCN Committee. Electroencephalogr Clin Neurophysiol (1993) 1.93
Shanxi Province Cervical Cancer Screening Study: a cross-sectional comparative trial of multiple techniques to detect cervical neoplasia. Gynecol Oncol (2001) 1.93
Laparoscopic nephrectomy: the experience of the laparoscopy working group of the German Urologic Association. J Urol (1998) 1.93
Cloning of murine Stat6 and human Stat6, Stat proteins that are tyrosine phosphorylated in responses to IL-4 and IL-3 but are not required for mitogenesis. Mol Cell Biol (1995) 1.85
Intravascular ultrasound assessment of lumen size and wall morphology in normal subjects and patients with coronary artery disease. Circulation (1991) 1.83
Long-term outcomes of chronic minimally conscious and vegetative states. Neurology (2010) 1.76
Radioiodine therapy of Graves' hyperthyroidism: standard vs. calculated 131iodine activity. Results from a prospective, randomized, multicentre study. Eur J Clin Invest (1995) 1.73
Identification of two genes from Streptomyces argillaceus encoding glycosyltransferases involved in transfer of a disaccharide during biosynthesis of the antitumor drug mithramycin. J Bacteriol (1998) 1.72
Visualizing gene expression in time and space in the filamentous bacterium Streptomyces coelicolor. Science (1988) 1.71
Two glycosyltransferases and a glycosidase are involved in oleandomycin modification during its biosynthesis by Streptomyces antibioticus. Mol Microbiol (1998) 1.65
Defective thymocyte proliferation and IL-2 production in transgenic mice expressing a dominant-negative form of CREB. Nature (1996) 1.65
Long-term efficacy of gamma knife radiosurgery in mesial temporal lobe epilepsy. Neurology (2008) 1.64
Offspring body condition and immunocompetence are negatively affected by high breeding densities in a colonial seabird: a multiscale approach. Proc Biol Sci (2001) 1.63
A cellular mechanism for the generation of ventricular arrhythmias by acetylstrophanthidin. Circ Res (1973) 1.62
Demonstration of a dual A-V nodal conduction system in the isolated rabbit heart. Circ Res (1966) 1.62
Single-point acupuncture and physiotherapy for the treatment of painful shoulder: a multicentre randomized controlled trial. Rheumatology (Oxford) (2008) 1.60
Searching for the exercise factor: is IL-6 a candidate? J Muscle Res Cell Motil (2003) 1.60
Characterization and repeat analysis of the compact genome of the freshwater pufferfish Tetraodon nigroviridis. Genome Res (2000) 1.57
Fine structure, physiology and biochemistry of arthrospore germination in Streptomyces antibioticus. J Gen Microbiol (1978) 1.52
Abnormal pulmonary artery pressure response in asymptomatic carriers of primary pulmonary hypertension gene. Circulation (2000) 1.46
The metabolic role of IL-6 produced during exercise: is IL-6 an exercise factor? Proc Nutr Soc (2004) 1.45
A selective imaging of tinnitus. Neuroreport (1999) 1.44
Autonomic nervous system and neuroendocrine changes in patients with idiopathic trigeminal neuralgia. Cephalalgia (1996) 1.44
The physiologic basis of reciprocal rhythm. Prog Cardiovasc Dis (1966) 1.44
Lateralization in autonomic dysfunction in ischemic stroke involving the insular cortex. Neuroreport (2004) 1.44
[Diagnosis of vitamin B12 deficiency revised]. Ned Tijdschr Geneeskd (2005) 1.43
Treatment of American cutaneous leishmaniasis with miltefosine, an oral agent. Clin Infect Dis (2001) 1.41
[Fifteen practical questions concerning gestational diabetes]. Gynecol Obstet Fertil (2007) 1.41
[What is the recurrence rate for Basedow's disease treated with thyrostatic agents. Answers from a prospective study]. Schweiz Med Wochenschr (1990) 1.39
[Chemoprevention of prostate cancer - a plea]. Aktuelle Urol (2012) 1.39
Loss of heterozygosity in sporadic human breast carcinoma: a common region between 11q22 and 11q23.3. Cancer Res (1994) 1.39
Novel splice donor site mutation in the cardiac myosin-binding protein-C gene in familial hypertrophic cardiomyopathy. Characterization Of cardiac transcript and protein. J Clin Invest (1997) 1.36
Excretion of ammonium by a nifL mutant of Azotobacter vinelandii fixing nitrogen. Appl Environ Microbiol (1992) 1.35
Genes and enzymes involved in deoxysugar biosynthesis in bacteria. Nat Prod Rep (1999) 1.35
Genetic and biochemical analysis of Staphylococcus epidermidis biofilm accumulation. Methods Enzymol (2001) 1.34
Recognition of distress and psychiatric morbidity in cancer patients: a multi-method approach. Ann Oncol (2004) 1.34
Altering the glycosylation pattern of bioactive compounds. Trends Biotechnol (2001) 1.34
Characterization of Streptomyces argillaceus genes encoding a polyketide synthase involved in the biosynthesis of the antitumor mithramycin. Gene (1996) 1.34
Protein and microsatellite single locus variability in Salmo salar L. (Atlantic salmon). Heredity (Edinb) (1996) 1.34
Coxsackievirus infection of the pancreas: evaluation of receptor expression, pathogenesis, and immunopathology. Virology (2000) 1.32
The role of ABC transporters in antibiotic-producing organisms: drug secretion and resistance mechanisms. Res Microbiol (2001) 1.31
Rodents as shared indicators for zoonotic parasites of carnivores in urban environments. Parasitology (2009) 1.30
Raptor nest decorations are a reliable threat against conspecifics. Science (2011) 1.29
Interaction of transmembrane potentials in canine Purkinje fibers and at Purkinje fiber-muscle junctions. Circ Res (1969) 1.29
Short-course of oral miltefosine for treatment of visceral leishmaniasis. Clin Infect Dis (2000) 1.29
Habitat, world geographic range, and embryonic development of hosts explain the prevalence of avian hematozoa at small spatial and phylogenetic scales. Proc Natl Acad Sci U S A (1999) 1.29
The product of the nitrogen fixation regulatory gene nfrX of Azotobacter vinelandii is functionally and structurally homologous to the uridylyltransferase encoded by glnD in enteric bacteria. J Bacteriol (1991) 1.28
Augmentation of lung liquid clearance via adenovirus-mediated transfer of a Na,K-ATPase beta1 subunit gene. J Clin Invest (1998) 1.27
Exploring haplotype sharing methods in general and isolated populations to detect gene(s) of a complex genetic trait. Genet Epidemiol (2001) 1.26
A newly created splice donor site in exon 25 of the MyBP-C gene is responsible for inherited hypertrophic cardiomyopathy with incomplete disease penetrance. Circulation (2000) 1.26
Cloning and insertional inactivation of Streptomyces argillaceus genes involved in the earliest steps of biosynthesis of the sugar moieties of the antitumor polyketide mithramycin. J Bacteriol (1997) 1.24
Effect of dexamethasone on in vivo prostanoid production in the rabbit. J Clin Invest (1984) 1.24
Oxidative cleavage of premithramycin B is one of the last steps in the biosynthesis of the antitumor drug mithramycin. Chem Biol (1999) 1.23
Metabolism of prostacyclin and 6-keto-prostaglandin F1 alpha in man. J Biol Chem (1980) 1.21
The alpha1 subunit of the sodium pump could represent a novel target to combat non-small cell lung cancers. J Pathol (2007) 1.21
Role of glycosylation and deglycosylation in biosynthesis of and resistance to oleandomycin in the producer organism, Streptomyces antibioticus. J Bacteriol (1992) 1.20
Identification and expression of genes involved in biosynthesis of L-oleandrose and its intermediate L-olivose in the oleandomycin producer Streptomyces antibioticus. Antimicrob Agents Chemother (2000) 1.19
Tumour DNA ploidy as an independent prognostic factor in breast cancer. Br J Cancer (1987) 1.18
A mutant TP53 gene status is associated with a poor prognosis and anthracycline-resistance in breast cancer patients. Eur J Cancer (2003) 1.18
Endometrial changes in postmenopausal breast cancer patients receiving tamoxifen. Obstet Gynecol (1993) 1.17
Down-regulation of Pax6 is associated with abnormal differentiation of corneal epithelial cells in severe ocular surface diseases. J Pathol (2008) 1.17
The mithramycin gene cluster of Streptomyces argillaceus contains a positive regulatory gene and two repeated DNA sequences that are located at both ends of the cluster. J Bacteriol (1999) 1.16
An ABC transporter is essential for resistance to the antitumor agent mithramycin in the producer Streptomyces argillaceus. Mol Gen Genet (1996) 1.16
[Conjunctival tumors]. Arch Soc Esp Oftalmol (2009) 1.16
Influence of Epstein-Barr virus genomes on patient survival in Hodgkin's disease. Am J Clin Pathol (1992) 1.16
Exercise and cytokines with particular focus on muscle-derived IL-6. Exerc Immunol Rev (2001) 1.16
Motor neuropathy with proximal multifocal persistent conduction block, fasciculations and myokymia. Evolution to tetraplegia. Eur Neurol (1986) 1.15
Two novel mutations in the GDAP1 and PRX genes in early onset Charcot-Marie-Tooth syndrome. Neuropediatrics (2008) 1.15
Activation of human endothelial cells by viable or heat-killed gram-negative bacteria requires soluble CD14. Infect Immun (1995) 1.15
Characterisation of a Streptomyces antibioticus gene encoding a type I polyketide synthase which has an unusual coding sequence. Mol Gen Genet (1994) 1.15
Association between the 5' UTR variant C178T of the serotonin receptor gene HTR3A and bipolar affective disorder. Pharmacogenetics (2001) 1.14
Two new tailoring enzymes, a glycosyltransferase and an oxygenase, involved in biosynthesis of the angucycline antibiotic urdamycin A in Streptomyces fradiae Tü2717. Microbiology (2000) 1.14
A cytochrome P450-like gene possibly involved in oleandomycin biosynthesis by Streptomyces antibioticus. FEMS Microbiol Lett (1995) 1.14
Loss of heterozygosity for chromosome 11 in primary human breast tumors is associated with poor survival after metastasis. Cancer Res (1995) 1.13
Characterization of two polyketide methyltransferases involved in the biosynthesis of the antitumor drug mithramycin by Streptomyces argillaceus. J Biol Chem (2000) 1.13
Elongation of the cytoplasmic tail interferes with the fusion activity of influenza virus hemagglutinin. J Virol (1998) 1.13
Evidence of founder mutations in Finnish BRCA1 and BRCA2 families. Am J Hum Genet (1998) 1.13
4-Hydroxynonenal prevents NF-kappaB activation and tumor necrosis factor expression by inhibiting IkappaB phosphorylation and subsequent proteolysis. J Biol Chem (1999) 1.12
A second ABC transporter is involved in oleandomycin resistance and its secretion by Streptomyces antibioticus. Mol Microbiol (1995) 1.12
The structure of mithramycin reinvestigated. J Nat Prod (1999) 1.12