DNA microarray analysis of genes involved in p53 mediated apoptosis: activation of Apaf-1.

PubWeight™: 1.37‹?› | Rank: Top 10%

🔗 View Article (PMID 11423996)

Published in Oncogene on June 07, 2001

Authors

K Kannan1, N Kaminski, G Rechavi, J Jakob-Hirsch, N Amariglio, D Givol

Author Affiliations

1: Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot 76100, Israel.

Articles citing this

Small-molecule MDM2 antagonists reveal aberrant p53 signaling in cancer: implications for therapy. Proc Natl Acad Sci U S A (2006) 4.68

An analysis of the clinical and biologic significance of TP53 loss and the identification of potential novel transcriptional targets of TP53 in multiple myeloma. Blood (2008) 1.93

Differential transactivation by the p53 transcription factor is highly dependent on p53 level and promoter target sequence. Mol Cell Biol (2002) 1.83

Human maintenance DNA (cytosine-5)-methyltransferase and p53 modulate expression of p53-repressed promoters. Proc Natl Acad Sci U S A (2005) 1.67

Glycogen synthase kinase-3beta (GSK3beta) binds to and promotes the actions of p53. J Biol Chem (2003) 1.56

Tumor-derived p53 mutants induce NF-kappaB2 gene expression. Mol Cell Biol (2005) 1.54

Lysosomal destabilization in p53-induced apoptosis. Proc Natl Acad Sci U S A (2002) 1.54

Evolution of p53 in hypoxia-stressed Spalax mimics human tumor mutation. Proc Natl Acad Sci U S A (2004) 1.41

Dysfunction of the TP53 tumor suppressor gene in lymphoid malignancies. Blood (2012) 1.25

Morpholino artifacts provide pitfalls and reveal a novel role for pro-apoptotic genes in hindbrain boundary development. Dev Biol (2010) 1.22

p53 responsive elements in human retrotransposons. Oncogene (2009) 1.15

Optimization of experimental design parameters for high-throughput chromatin immunoprecipitation studies. Nucleic Acids Res (2008) 1.12

Repression of the antiapoptotic molecule galectin-3 by homeodomain-interacting protein kinase 2-activated p53 is required for p53-induced apoptosis. Mol Cell Biol (2006) 1.09

Apoptosis and colorectal cancer. Gut (2004) 1.05

G1 checkpoint failure and increased tumor susceptibility in mice lacking the novel p53 target Ptprv. EMBO J (2005) 0.99

The absence of Ser389 phosphorylation in p53 affects the basal gene expression level of many p53-dependent genes and alters the biphasic response to UV exposure in mouse embryonic fibroblasts. Mol Cell Biol (2008) 0.98

GIMAP Proteins in T-Lymphocytes. J Signal Transduct (2010) 0.92

Expression of GIMAP1, a GTPase of the immunity-associated protein family, is not up-regulated in malaria. Malar J (2009) 0.88

SUMO-conjugating enzyme E2 UBC9 mediates viral immediate-early protein SUMOylation in crayfish to facilitate reproduction of white spot syndrome virus. J Virol (2012) 0.86

A resource for discovering specific and universal biomarkers for distributed stem cells. PLoS One (2011) 0.85

The DNA repair complex Ku70/86 modulates Apaf1 expression upon DNA damage. Cell Death Differ (2010) 0.85

Preeclampsia is associated with alterations in the p53-pathway in villous trophoblast. PLoS One (2014) 0.85

Functional mimicry of the acetylated C-terminal tail of p53 by a SUMO-1 acetylated domain, SAD. J Cell Physiol (2010) 0.84

Soft-shell clam (Mya arenaria) p53: a structural and functional comparison to human p53. Gene (2008) 0.82

The reversal of drug-resistance in tumors using a drug-carrying nanoparticular system. Int J Mol Sci (2009) 0.80

Cell free expression of hif1α and p21 in maternal peripheral blood as a marker for preeclampsia and fetal growth restriction. PLoS One (2012) 0.79

Microarray-based expression profiling of normal and malignant immune cells. Endocr Rev (2002) 0.78

Contribution of Upregulated Dipeptidyl peptidase 9 (DPP9) in promoting tumoregenicity, metastasis and the prediction of poor prognosis in non-small cell lung cancer (NSCLC). Int J Cancer (2016) 0.77

Next-generation sequencing of apoptotic DNA breakpoints reveals association with actively transcribed genes and gene translocations. PLoS One (2011) 0.77

ERK mediated upregulation of death receptor 5 overcomes the lack of p53 functionality in the diaminothiazole DAT1 induced apoptosis in colon cancer models: efficiency of DAT1 in Ras-Raf mutated cells. Mol Cancer (2016) 0.75

Apoptotic pathways as a therapeutic target for colorectal cancer treatment. World J Gastrointest Oncol (2016) 0.75

Survival of mature T cells in the periphery is intrinsically dependent on GIMAP1 in mice. Eur J Immunol (2016) 0.75

Articles by these authors

The integrin alpha v beta 6 binds and activates latent TGF beta 1: a mechanism for regulating pulmonary inflammation and fibrosis. Cell (1999) 11.59

Participation of p53 cellular tumour antigen in transformation of normal embryonic cells. Nature (1985) 6.86

Sequence of chicken ovalbumin mRNA. Nature (1978) 6.73

Nucleotide sequence of the rat skeletal muscle actin gene. Nature (1982) 3.81

Induction of WAF1/CIP1 by a p53-independent pathway. Cancer Res (1994) 3.54

TGF-beta is a critical mediator of acute lung injury. J Clin Invest (2001) 3.29

DNA microarrays identification of primary and secondary target genes regulated by p53. Oncogene (2001) 3.28

Human p53 cellular tumor antigen: cDNA sequence and expression in COS cells. EMBO J (1985) 3.18

A single gene and a pseudogene for the cellular tumour antigen p53. Nature (1984) 2.98

Developmental localization of the splicing alternatives of fibroblast growth factor receptor-2 (FGFR2). Dev Biol (1993) 2.96

Analysis of the gene coding for the murine cellular tumour antigen p53. EMBO J (1984) 2.94

Peripheral blood mononuclear cell gene expression profiles identify emergent post-traumatic stress disorder among trauma survivors. Mol Psychiatry (2005) 2.89

Skeletal muscle actin mRNA. Characterization of the 3' untranslated region. Nucleic Acids Res (1981) 2.67

Localization of gene for human p53 tumour antigen to band 17p13. Nature (1986) 2.56

V(D)J recombination defects in lymphocytes due to RAG mutations: severe immunodeficiency with a spectrum of clinical presentations. Blood (2001) 2.50

Diversity of germ-line immunoglobulin VH genes. Nature (1981) 2.47

All autophosphorylation sites of epidermal growth factor (EGF) receptor and HER2/neu are located in their carboxyl-terminal tails. Identification of a novel site in EGF receptor. J Biol Chem (1989) 2.46

Activation of a cellular oncogene by DNA rearrangement: possible involvement of an IS-like element. Nature (1982) 2.45

A possible role for CXCR4 and its ligand, the CXC chemokine stromal cell-derived factor-1, in the development of bone marrow metastases in neuroblastoma. J Immunol (2001) 2.33

Activation of the c-mos oncogene in a mouse plasmacytoma by insertion of an endogenous intracisternal A-particle genome. Proc Natl Acad Sci U S A (1983) 2.23

Differential mRNA stability to reticulocyte ribonucleases correlates with 3' non-coding (U)nA sequences. Eur J Biochem (1988) 2.19

Simple DNA sequences in homologous flanking regions near immunoglobulin VH genes: a role in gene interaction? Nucleic Acids Res (1982) 2.19

The gene for human p53 cellular tumor antigen is located on chromosome 17 short arm (17p13). Proc Natl Acad Sci U S A (1986) 2.18

Organization and evolution of immunoglobulin VH gene subgroups. Proc Natl Acad Sci U S A (1982) 2.18

The 5' region of the p53 gene: evolutionary conservation and evidence for a negative regulatory element. EMBO J (1985) 2.17

Developmental expression of two murine fibroblast growth factor receptors, flg and bek. Development (1991) 2.16

Developmental expression of c-kit, a proto-oncogene encoded by the W locus. Development (1990) 1.99

Homology between an endogenous viral LTR and sequences inserted in an activated cellular oncogene. Nature (1983) 1.98

Receptor for acidic fibroblast growth factor is related to the tyrosine kinase encoded by the fms-like gene (FLG). Proc Natl Acad Sci U S A (1989) 1.97

A confined variable region confers ligand specificity on fibroblast growth factor receptors: implications for the origin of the immunoglobulin fold. EMBO J (1992) 1.93

General method for the detection of cells producing antibodies against haptens and proteins. Nature (1970) 1.92

Functional analysis of the ligand binding site of EGF-receptor utilizing chimeric chicken/human receptor molecules. EMBO J (1989) 1.90

Gene expression profiling of parkinsonian substantia nigra pars compacta; alterations in ubiquitin-proteasome, heat shock protein, iron and oxidative stress regulated proteins, cell adhesion/cellular matrix and vesicle trafficking genes. J Neural Transm (Vienna) (2004) 1.89

The human protooncogene product p33pim is expressed during fetal hematopoiesis and in diverse leukemias. Proc Natl Acad Sci U S A (1989) 1.86

Rearrangements in the p53 gene in Philadelphia chromosome positive chronic myelogenous leukemia. Blood (1989) 1.85

Localization of antibody-combining sites within the variable portions of heavy and light chains. Proc Natl Acad Sci U S A (1972) 1.84

Chicken epidermal growth factor (EGF) receptor: cDNA cloning, expression in mouse cells, and differential binding of EGF and transforming growth factor alpha. Mol Cell Biol (1988) 1.77

Antigen-induced conformational changes in antibodies and their Fab fragments studied by circular polarization of fluorescence. Proc Natl Acad Sci U S A (1975) 1.76

A mouse model for achondroplasia produced by targeting fibroblast growth factor receptor 3. Proc Natl Acad Sci U S A (1999) 1.75

Evolutionary aspects of immunoglobulin heavy chain variable region (VH) gene subgroups. Proc Natl Acad Sci U S A (1983) 1.72

A general method for the specific isolation of peptides containing modified residues, using insoluble antibody columns. Biochemistry (1971) 1.70

Common peptides from the N-terminal half of heavy chain of immunoglobulin G from normal rabbit serum and a specific antibody. Biochem J (1968) 1.69

Kinetic mapping of the antibody combining site by chemical relaxation spectrometry. Biochemistry (1974) 1.68

An active antibody fragment (Fv) composed of the variable portions of heavy and light chains. Biochemistry (1973) 1.68

Localization of a major receptor-binding domain for epidermal growth factor by affinity labeling. Mol Cell Biol (1988) 1.67

Rearrangement of the oncogene c-mos in mouse myeloma NSI and hybridomas. Nature (1984) 1.66

Carcinoid tumors frequently display genetic abnormalities involving chromosome 11. J Clin Endocrinol Metab (1996) 1.65

The CC2D1A, a member of a new gene family with C2 domains, is involved in autosomal recessive non-syndromic mental retardation. J Med Genet (2005) 1.65

Cloning and expression of a widely expressed receptor tyrosine phosphatase. Proc Natl Acad Sci U S A (1990) 1.61

Nucleotide sequence analysis identifies the human c-sis proto-oncogene as a structural gene for platelet-derived growth factor. Cell (1984) 1.61

The nucleotide sequence of rat alpha-tubulin: 3'-end characteristics, and evolutionary conservation. Nucleic Acids Res (1981) 1.58

"Retroposon" insertion into the cellular oncogene c-myc in canine transmissible venereal tumor. Proc Natl Acad Sci U S A (1985) 1.56

Analysis of recombinant DNA clones specific for the murine p53 cellular tumor antigen. EMBO J (1983) 1.55

Model-building studies of antigen-binding sites: the hapten-binding site of mopc-315. Cold Spring Harb Symp Quant Biol (1977) 1.54

Nuclear membrane protein LAP2beta mediates transcriptional repression alone and together with its binding partner GCL (germ-cell-less). J Cell Sci (2001) 1.51

Gene expression profiles of AML derived stem cells; similarity to hematopoietic stem cells. Leukemia (2006) 1.50

Correlated expression of VH framework and VH idiotypic determinants on T helper cells and on functionally undefined T cells binding group A streptococcal carbohydrate. Eur J Immunol (1980) 1.50

Interleukin-13 induces dramatically different transcriptional programs in three human airway cell types. Am J Respir Cell Mol Biol (2001) 1.48

Chromosomal translocation (1:13) in a case of alveolar rhabdomyosarcoma. J Pediatr Hematol Oncol (1998) 1.48

Purification and properties of an enzyme from beef liver which catalyzes sulfhydryl-disulfide interchange in proteins. J Biol Chem (1966) 1.48

Sporadic amplification of the HER2/neu protooncogene in adenocarcinomas of various tissues. Cancer Res (1988) 1.45

Malignant osteopetrosis manifested as juvenile chronic myeloid leukemia. Pediatr Hematol Oncol (1993) 1.44

Brief report: lymphoma with recurrent cycles of spontaneous remission and relapse--possible role of apoptosis. N Engl J Med (1995) 1.42

Infantile idiopathic thrombocytopenic purpura. Pediatr Hematol Oncol (1990) 1.42

Regulation of p53 activity by HIPK2: molecular mechanisms and therapeutical implications in human cancer cells. Oncogene (2010) 1.42

Effects of perfusion pressure and renal flow upon albumin excretion in isolated perfused kidneys. Nephron (1990) 1.40

Promoter and enhancer elements in the rearranged alpha chain gene of the human T cell receptor. EMBO J (1987) 1.40

A specific combination of substrates is involved in signal transduction by the kit-encoded receptor. EMBO J (1991) 1.39

Chromosomal aberrations and gene expression profiles in non-small cell lung cancer. Lung Cancer (2007) 1.38

The chemical structure of the heavy chains of rabbit and human immunoglobulin G (IgG). Proc R Soc Lond B Biol Sci (1966) 1.36

The characterization and localization of the mouse thymopoietin/lamina-associated polypeptide 2 gene and its alternatively spliced products. Genome Res (1996) 1.33

The CXCR4 antagonist AMD3100 impairs survival of human AML cells and induces their differentiation. Leukemia (2008) 1.33

Molecular cloning, sequencing, chromosomal localization and expression of mouse p21 (Waf1). Oncogene (1994) 1.31

KIT ligand (mast cell growth factor) inhibits the growth of KIT-expressing melanoma cells. Oncogene (1993) 1.30

Parallel induction of ATM-dependent pro- and antiapoptotic signals in response to ionizing radiation in murine lymphoid tissue. Oncogene (2006) 1.29

Preparation and characterization of anti-framework antibodies to the heavy chain variable region (VH) of mouse immunoglobulins. Eur J Immunol (1978) 1.29

Cloning and sequence of the cDNA corresponding to the variable region of immunoglobulin heavy chain MPC11. Nucleic Acids Res (1980) 1.29

Human HER2 (neu) promoter: evidence for multiple mechanisms for transcriptional initiation. Mol Cell Biol (1987) 1.28

Neural expression and chromosomal mapping of Neu differentiation factor to 8p12-p21. Proc Natl Acad Sci U S A (1993) 1.28