Published in Proc Natl Acad Sci U S A on June 26, 2001
A DNA repair system specific for thermophilic Archaea and bacteria predicted by genomic context analysis. Nucleic Acids Res (2002) 4.39
The genome of Sulfolobus acidocaldarius, a model organism of the Crenarchaeota. J Bacteriol (2005) 2.31
Drift-barrier hypothesis and mutation-rate evolution. Proc Natl Acad Sci U S A (2012) 2.08
Biogeography of the Sulfolobus islandicus pan-genome. Proc Natl Acad Sci U S A (2009) 1.95
The rate and character of spontaneous mutation in an RNA virus. Genetics (2002) 1.79
Response of the hyperthermophilic archaeon Sulfolobus solfataricus to UV damage. J Bacteriol (2007) 1.46
Genome-wide patterns of nucleotide substitution reveal stringent functional constraints on the protein sequences of thermophiles. Genetics (2004) 1.44
Responses of hyperthermophilic crenarchaea to UV irradiation. Genome Biol (2007) 1.41
Avoiding dangerous missense: thermophiles display especially low mutation rates. PLoS Genet (2009) 1.40
A novel nuclease-ATPase (Nar71) from archaea is part of a proposed thermophilic DNA repair system. Nucleic Acids Res (2004) 1.39
Too many mutants with multiple mutations. Crit Rev Biochem Mol Biol (2007) 1.38
Clusters of mutations from transient hypermutability. Proc Natl Acad Sci U S A (2005) 1.35
Patterns of gene flow define species of thermophilic Archaea. PLoS Biol (2012) 1.33
Mutations and rearrangements in the genome of Sulfolobus solfataricus P2. J Bacteriol (2006) 1.25
Viral diversity threshold for adaptive immunity in prokaryotes. MBio (2012) 1.17
An unusual pattern of spontaneous mutations recovered in the halophilic archaeon Haloferax volcanii. Genetics (2006) 1.07
On the mutation rate of herpes simplex virus type 1. Genetics (2005) 1.06
Mutator suppression and escape from replication error-induced extinction in yeast. PLoS Genet (2011) 1.05
Uracil recognition by replicative DNA polymerases is limited to the archaea, not occurring with bacteria and eukarya. Nucleic Acids Res (2007) 1.04
Life in hot acid: pathway analyses in extremely thermoacidophilic archaea. Curr Opin Biotechnol (2008) 1.01
The anomalous effects of biased mutation. Genetics (2003) 0.98
Molecular characteristics of spontaneous deletions in the hyperthermophilic archaeon Sulfolobus acidocaldarius. J Bacteriol (2003) 0.98
The rate and character of spontaneous mutation in Thermus thermophilus. Genetics (2008) 0.96
Conjugational genetic exchange in the hyperthermophilic archaeon Sulfolobus acidocaldarius: intragenic recombination with minimal dependence on marker separation. J Bacteriol (2005) 0.96
Cytosine methylation by the SuaI restriction-modification system: implications for genetic fidelity in a hyperthermophilic archaeon. J Bacteriol (2003) 0.94
Chaos and order in spontaneous mutation. Genetics (2006) 0.92
How hyperthermophiles adapt to change their lives: DNA exchange in extreme conditions. Extremophiles (2013) 0.90
Genes of de novo pyrimidine biosynthesis from the hyperthermoacidophilic crenarchaeote Sulfolobus acidocaldarius: novel organization in a bipolar operon. J Bacteriol (2002) 0.88
Lipopolysaccharide-Deficient Brucella Variants Arise Spontaneously during Infection. Front Microbiol (2011) 0.88
Counterselection system for Geobacillus kaustophilus HTA426 through disruption of pyrF and pyrR. Appl Environ Microbiol (2012) 0.88
Sulfolobus mutants, generated via PCR products, which lack putative enzymes of UV photoproduct repair. Archaea (2011) 0.87
Microbial communities evolve faster in extreme environments. Sci Rep (2014) 0.86
Understanding DNA Repair in Hyperthermophilic Archaea: Persistent Gaps and Other Reasons to Focus on the Fork. Archaea (2015) 0.85
Spontaneous trpY mutants and mutational analysis of the TrpY archaeal transcription regulator. J Bacteriol (2007) 0.85
Mutation and reversion frequencies of different Sulfolobus species and strains. Extremophiles (2008) 0.83
Discontinuity and limited linkage in the homologous recombination system of a hyperthermophilic archaeon. J Bacteriol (2010) 0.83
Heteroduplex formation, mismatch resolution, and genetic sectoring during homologous recombination in the hyperthermophilic archaeon sulfolobus acidocaldarius. Front Microbiol (2012) 0.82
Biochemical evidence of a physical interaction between Sulfolobus solfataricus B-family and Y-family DNA polymerases. Extremophiles (2006) 0.82
MutS and MutL are dispensable for maintenance of the genomic mutation rate in the halophilic archaeon Halobacterium salinarum NRC-1. PLoS One (2010) 0.81
Roles of the Y-family DNA polymerase Dbh in accurate replication of the Sulfolobus genome at high temperature. DNA Repair (Amst) (2012) 0.81
Quantitative analysis of the mutagenic potential of 1-aminopyrene-DNA adduct bypass catalyzed by Y-family DNA polymerases. Mutat Res (2012) 0.81
An extended network of genomic maintenance in the archaeon Pyrococcus abyssi highlights unexpected associations between eucaryotic homologs. PLoS One (2013) 0.80
Genomic evidence of rapid, global-scale gene flow in a Sulfolobus species. ISME J (2012) 0.78
Confounders of mutation-rate estimators: selection and phenotypic lag in Thermus thermophilus. Mutat Res (2013) 0.77
Identification of an unfolding intermediate for a DNA lesion bypass polymerase. Chem Res Toxicol (2012) 0.77
Accurate DNA synthesis by Sulfolobus solfataricus DNA polymerase B1 at high temperature. Extremophiles (2009) 0.77
DNA Processing Proteins Involved in the UV-Induced Stress Response of Sulfolobales. J Bacteriol (2015) 0.77
Loss of genetic accuracy in mutants of the thermoacidophile Sulfolobus acidocaldarius. Archaea (2002) 0.77
Identification of a mismatch-specific endonuclease in hyperthermophilic Archaea. Nucleic Acids Res (2016) 0.76
A mutant ('lab strain') of the hyperthermophilic archaeon Pyrococcus furiosus, lacking flagella, has unusual growth physiology. Extremophiles (2014) 0.76
Lesion-Induced Mutation in the Hyperthermophilic Archaeon Sulfolobus acidocaldarius and Its Avoidance by the Y-Family DNA Polymerase Dbh. Genetics (2015) 0.75
Adaptive engineering of a hyperthermophilic archaeon on CO and discovering the underlying mechanism by multi-omics analysis. Sci Rep (2016) 0.75
The apt/6-Methylpurine Counterselection System and Its Applications in Genetic Studies of the Hyperthermophilic Archaeon Sulfolobus islandicus. Appl Environ Microbiol (2016) 0.75
Sequence-Dependent T:G Base Pair Opening in DNA Double Helix Bound by Cren7, a Chromatin Protein Conserved among Crenarchaea. PLoS One (2016) 0.75
Volatility of Mutator Phenotypes at Single Cell Resolution. PLoS Genet (2015) 0.75
Endogenous mutagenesis in recombinant sulfolobus plasmids. J Bacteriol (2013) 0.75
How a Genetically Stable Extremophile Evolves: Modes of Genome Diversification in the Archaeon Sulfolobus acidocaldarius. J Bacteriol (2017) 0.75
Disruption of the gene encoding restriction endonuclease SuaI and development of a host-vector system for the thermoacidophilic archaeon Sulfolobus acidocaldarius. Extremophiles (2016) 0.75
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High spontaneous mutation rate in the hyperthermophilic archaeon Sulfolobus solfataricus is mediated by transposable elements. J Bacteriol (2000) 2.06
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Sulfolobus acidocaldarius synthesizes UMP via a standard de novo pathway: results of biochemical-genetic study. J Bacteriol (1993) 1.74
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Effect of reaction pH on the fidelity and processivity of exonuclease-deficient Klenow polymerase. J Biol Chem (1993) 1.51
Characterization of intragenic recombination in a hyperthermophilic archaeon via conjugational DNA exchange. J Bacteriol (2001) 1.40
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The question of DNA repair in hyperthermophilic archaea. Trends Microbiol (2000) 1.23
Hyperthermophiles and the problem of DNA instability. Mol Microbiol (1998) 1.22
Fidelity of DNA synthesis catalyzed by human DNA polymerase alpha and HIV-1 reverse transcriptase: effect of reaction pH. Nucleic Acids Res (1993) 1.15
A physical map of the sulfur-dependent archaebacterium Sulfolobus acidocaldarius 7 chromosome. J Bacteriol (1993) 1.11
Characterization and purification of a membrane-bound archaebacterial pyrophosphatase from Sulfolobus acidocaldarius. Eur J Biochem (1992) 0.99
Aspects of the ultraviolet photobiology of some T-even bacteriophages. Genetics (1998) 0.92
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Duplication-targeted DNA methylation and mutagenesis in the evolution of eukaryotic chromosomes. Proc Natl Acad Sci U S A (1992) 1.64
Interacting fidelity defects in the replicative DNA polymerase of bacteriophage RB69. J Biol Chem (2000) 1.48
Heteroduplex heterozygotes in bacteriophage T4 involving mutations of various dimensions. Proc Natl Acad Sci U S A (1966) 1.44
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Spontaneous mutations accumulating in bacteriophage T4 in the complete absence of DNA replication. Proc Natl Acad Sci U S A (1966) 1.35
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Ultraviolet mutagenesis in bacteriophage T-4. I. Irradiation of extracellular phage particles. J Bacteriol (1966) 1.29
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The genetic control of spontaneous and induced mutation rates in bacteriophage T4. Genetics (1973) 1.28
Heat mutagenesis in bacteriophage T4: the transition pathway. Proc Natl Acad Sci U S A (1976) 1.24
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Suppression of chemical mutagenesis in bacteriophage T4 by genetically modified DNA polymerases. Proc Natl Acad Sci U S A (1970) 1.17
Modulation of mutation rates in bacteriophage T4 by a base-pair change a dozen nucleotides removed. J Mol Biol (1984) 1.15
Isolation and characterization of conditional alleles of bacteriophage T4 genes uvsX and uvsY. Genetics (1984) 1.14
Mechanics of frameshift mutagenesis in bacteriophage T4: role of chromosome tips. Proc Natl Acad Sci U S A (1970) 1.09
Bisulfite mutagenesis in bacteriophage T4. Genetics (1971) 1.07
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Conditional coupling of leading-strand and lagging-strand DNA synthesis at bacteriophage T4 replication forks. J Biol Chem (2001) 1.04
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Inactivation of bacteriophage T4 by ethyl methanesulfonate: influence of host and viral genotypes. J Virol (1972) 1.02
Gamma-ray mutagenesis in bacteriophage T4. Genetics (1976) 1.01
Retention of replication fidelity by a DNA polymerase functioning in a distantly related environment. Proc Natl Acad Sci U S A (1997) 1.00
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Ultraviolet mutagenesis in bacteriophage T4. II. Photoreversal of mutational lesions. J Bacteriol (1966) 0.99
Lysis and lysis inhibition in bacteriophage T4: rV mutations reside in the holin t gene. J Bacteriol (1999) 0.98
The length of the homologous pairing region for genetic recombination in bacteriophage T4. Proc Natl Acad Sci U S A (1967) 0.96
Rates of spontaneous mutation in bacteriophage T4 are independent of host fidelity determinants. Genetics (1994) 0.96
Measurements of certain environmental tobacco smoke components on long-range flights. Aviat Space Environ Med (1990) 0.95
Mutator mutations in bacteriophage T4 gene 42 (dHMC hydroxymethylase). Genetics (1977) 0.92
Aspects of the ultraviolet photobiology of some T-even bacteriophages. Genetics (1998) 0.92
Thermal rescue of UV-irradiated bacteriophage T4 and biphasic mode of action of the WXY system. Genetics (1984) 0.91
Isolation and genetic characterization of new uvsW alleles of bacteriophage T4. Mol Gen Genet (1990) 0.88
A genetic assay for transversion mutations in bacteriophage T4. Mol Gen Genet (1972) 0.88
Mutator mutations in bacteriophage T4 gene 32 (DNA unwinding protein). J Virol (1976) 0.87
Action of cobalt chloride on the biosynthesis, degradation, and utilization of heme in fetal rat liver. Drug Metab Dispos (1977) 0.86
A new epistasis group for the repair of DNA damage in bacteriophage T4: replication repair. Genetics (1987) 0.85
Is bacteriophage T4 DNA polymerase involved in the repair of ultraviolet damage? Virology (1974) 0.84
Species-dependent expression and induction of homologues of rabbit cytochrome P-450 isozyme 5 in liver and lung. Mol Pharmacol (1987) 0.84
Heat mutagenesis in bacteriophage T4: another walk down the transversion pathway. J Bacteriol (1990) 0.83
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Some irregularities in the nomenclature of bacteriophage T4 DNA polymerase amber mutants. Genetics (1971) 0.79
Expression and characterization of a modified flavin-containing monooxygenase 4 from humans. J Biol Chem (1996) 0.78
Photodynamic inactivation and mutagenesis by angelicin (isopsoralen) or thiopyronin (methylene red) in wild-type and repair-deficient strains of bacteriophage T4. J Bacteriol (1985) 0.78
Methyl methanesulfonate mutagenesis in bacteriophage T4. Genetics (1982) 0.78
Bacteriophage T4 rnh (RNase H) null mutations: effects on spontaneous mutation and epistatic interaction with rII mutations. J Bacteriol (1999) 0.77
Altered regulation of hepatic heme metabolism by indium chloride. Toxicol Appl Pharmacol (1979) 0.76
Distribution of cytochrome P450 1A1 and NADPH-cytochrome P450 reductase in lungs of rabbits treated with 2,3,7,8-tetrachlorodibenzo-p-dioxin: ultrastructural immunolocalization and in situ hybridization. Mol Pharmacol (1992) 0.75
A curriculum in transition. Caementum (1968) 0.75
Rationale for deployment of short-term assays for evidence of carcinogenicity. IARC Monogr Eval Carcinog Risk Chem Hum Suppl (1980) 0.75
New guanylic for old. Science (1976) 0.75
A dean retires. Caementum (1967) 0.75
The invariance of mutation rates in bacteriophage T4 as functions of medium pH. Mutat Res (1973) 0.75
An environmental mutagenesis test development programme. IARC Sci Publ (1980) 0.75
Intra-oral fluoroscope developed at UODS. Dent Angles (1969) 0.75
The 1995 Thomas Hunt Morgan Medal. Matthew Meselson. Genetics (1996) 0.75
Faculty explores curriculum changes. Dent Angles (1967) 0.75
A Junior Dentists' Institute. A Career Guidance Program. J Am Coll Dent (1968) 0.75
A progress report: the Junior Dentists' Institute. Caementum (1969) 0.75
Environmental mutagenesis: evolving strategies in the USA. Mutat Res (1975) 0.75
The 1996 Thomas Hunt Morgan Medal Franklin W. Stahl. Genetics (1997) 0.75
Perspectives in molecular mutagenesis. Basic Life Sci (1982) 0.75
Viewing the complexities of mutagenesis from an evolutionary perspective. Basic Life Sci (1985) 0.75
The effect of [4,4'-(isopropylidenethio)bis(2,6-di-t-butylphenol)] (DH-581) on serum lipids and lipoproteins in human subjects. Metabolism (1969) 0.75
An interview: Dean Noyes charts past, future of dental education. Dent Angles (1967) 0.75