Published in Proc Natl Acad Sci U S A on July 17, 2001
Role of RAD52 epistasis group genes in homologous recombination and double-strand break repair. Microbiol Mol Biol Rev (2002) 8.50
Identification and purification of two distinct complexes containing the five RAD51 paralogs. Genes Dev (2001) 2.54
Interplay between human DNA repair proteins at a unique double-strand break in vivo. EMBO J (2006) 2.09
Mediator function of the human Rad51B-Rad51C complex in Rad51/RPA-catalyzed DNA strand exchange. Genes Dev (2001) 1.95
HELQ promotes RAD51 paralogue-dependent repair to avert germ cell loss and tumorigenesis. Nature (2013) 1.57
Mammalian Rad51C contributes to DNA cross-link resistance, sister chromatid cohesion and genomic stability. Nucleic Acids Res (2002) 1.52
Involvement of Rad51C in two distinct protein complexes of Rad51 paralogs in human cells. Nucleic Acids Res (2002) 1.35
Interactions involving the Rad51 paralogs Rad51C and XRCC3 in human cells. Nucleic Acids Res (2002) 1.31
Differential and collaborative actions of Rad51 paralog proteins in cellular response to DNA damage. Nucleic Acids Res (2005) 1.30
Replication blocking lesions present a unique substrate for homologous recombination. EMBO J (2007) 1.29
Loss of Rad51c leads to embryonic lethality and modulation of Trp53-dependent tumorigenesis in mice. Cancer Res (2009) 1.25
The Drosophila spn-D gene encodes a RAD51C-like protein that is required exclusively during meiosis. Genetics (2003) 1.24
Preferential binding to branched DNA strands and strand-annealing activity of the human Rad51B, Rad51C, Rad51D and Xrcc2 protein complex. Nucleic Acids Res (2004) 1.23
Cellular redistribution of Rad51 in response to DNA damage: novel role for Rad51C. J Biol Chem (2009) 1.23
Domain mapping of the Rad51 paralog protein complexes. Nucleic Acids Res (2004) 1.14
RAD51C germline mutations in breast and ovarian cancer cases from high-risk families. PLoS One (2011) 1.12
The splicing-factor related protein SFPQ/PSF interacts with RAD51D and is necessary for homology-directed repair and sister chromatid cohesion. Nucleic Acids Res (2010) 1.12
Homologous recombination is required for AAV-mediated gene targeting. Nucleic Acids Res (2006) 1.11
Oversized AAV transductifon is mediated via a DNA-PKcs-independent, Rad51C-dependent repair pathway. Mol Ther (2013) 1.02
Ring-shaped Rad51 paralog protein complexes bind Holliday junctions and replication forks as visualized by electron microscopy. J Biol Chem (2010) 0.96
RAD51 protein ATP cap regulates nucleoprotein filament stability. J Biol Chem (2012) 0.92
Disparate requirements for the Walker A and B ATPase motifs of human RAD51D in homologous recombination. Nucleic Acids Res (2006) 0.92
Biochemistry of eukaryotic homologous recombination. Top Curr Genet (2007) 0.91
A molecular portrait of Arabidopsis meiosis. Arabidopsis Book (2006) 0.90
Region and amino acid residues required for Rad51C binding in the human Xrcc3 protein. Nucleic Acids Res (2003) 0.89
The HsRAD51B-HsRAD51C stabilizes the HsRAD51 nucleoprotein filament. DNA Repair (Amst) (2013) 0.85
Interactions among Trypanosoma brucei RAD51 paralogues in DNA repair and antigenic variation. Mol Microbiol (2011) 0.82
DNA repair polymorphisms and outcome of chemotherapy for acute myelogenous leukemia: a report from the Children's Oncology Group. Leukemia (2007) 0.82
XRCC2 is Required for the Formation of Rad51 Foci Induced by Ionizing Radiation and DNA Cross-Linking Agent Mitomycin C. J Biomed Biotechnol (2002) 0.80
Oxidative stress in mammalian cells impinges on the cysteines redox state of human XRCC3 protein and on its cellular localization. PLoS One (2013) 0.78
Roles of Rad51 paralogs for promoting homologous recombination in Leishmania infantum. Nucleic Acids Res (2015) 0.78
Mutation screening of RAD51C in high-risk breast and ovarian cancer families. Fam Cancer (2012) 0.78
Overexpression of Rad51 Predicts Poor Prognosis in Colorectal Cancer: Our Experience with 54 Patients. PLoS One (2017) 0.75
A recombinase paralog from the hyperthermophilic crenarchaeon Sulfolobus solfataricus enhances SsoRadA ssDNA binding and strand displacement. Gene (2012) 0.75
A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage. Curr Biol (2000) 13.46
XRCC3 promotes homology-directed repair of DNA damage in mammalian cells. Genes Dev (1999) 9.50
Association of BRCA1 with Rad51 in mitotic and meiotic cells. Cell (1997) 8.28
Rad51-deficient vertebrate cells accumulate chromosomal breaks prior to cell death. EMBO J (1998) 6.65
Targeted disruption of the Rad51 gene leads to lethality in embryonic mice. Proc Natl Acad Sci U S A (1996) 6.04
A mutation in mouse rad51 results in an early embryonic lethal that is suppressed by a mutation in p53. Mol Cell Biol (1996) 5.75
Role of BRCA2 in control of the RAD51 recombination and DNA repair protein. Mol Cell (2001) 5.59
Rad52 protein stimulates DNA strand exchange by Rad51 and replication protein A. Nature (1998) 4.93
Disruption of mouse RAD54 reduces ionizing radiation resistance and homologous recombination. Cell (1997) 4.78
Yeast Rad55 and Rad57 proteins form a heterodimer that functions with replication protein A to promote DNA strand exchange by Rad51 recombinase. Genes Dev (1997) 4.57
Purification and characterization of the human Rad51 protein, an analogue of E. coli RecA. EMBO J (1994) 4.55
Function of yeast Rad52 protein as a mediator between replication protein A and the Rad51 recombinase. J Biol Chem (1997) 4.53
Stimulation by Rad52 of yeast Rad51-mediated recombination. Nature (1998) 4.31
Chromosome instability and defective recombinational repair in knockout mutants of the five Rad51 paralogs. Mol Cell Biol (2001) 4.19
Stable interaction between the products of the BRCA1 and BRCA2 tumor suppressor genes in mitotic and meiotic cells. Mol Cell (1998) 3.86
Complex formation in yeast double-strand break repair: participation of Rad51, Rad52, Rad55, and Rad57 proteins. Proc Natl Acad Sci U S A (1995) 3.79
Catalysis of homologous DNA pairing by yeast Rad51 and Rad54 proteins. Nature (1998) 3.75
XRCC2 and XRCC3, new human Rad51-family members, promote chromosome stability and protect against DNA cross-links and other damages. Mol Cell (1998) 3.73
Synergistic actions of Rad51 and Rad52 in recombination and DNA repair. Nature (1998) 3.57
Mammalian XRCC2 promotes the repair of DNA double-strand breaks by homologous recombination. Nature (1999) 3.24
Reduced X-ray resistance and homologous recombination frequencies in a RAD54-/- mutant of the chicken DT40 cell line. Cell (1997) 3.23
Functional differences and interactions among the putative RecA homologs Rad51, Rad55, and Rad57. Mol Cell Biol (1995) 2.96
Targeted inactivation of mouse RAD52 reduces homologous recombination but not resistance to ionizing radiation. Mol Cell Biol (1998) 2.93
17q23 amplifications in breast cancer involve the PAT1, RAD51C, PS6K, and SIGma1B genes. Cancer Res (2000) 2.81
Correction of chromosomal instability and sensitivity to diverse mutagens by a cloned cDNA of the XRCC3 DNA repair gene. Proc Natl Acad Sci U S A (1995) 2.48
Xrcc3 is required for assembly of Rad51 complexes in vivo. J Biol Chem (1998) 2.44
The Rad51 paralog Rad51B promotes homologous recombinational repair. Mol Cell Biol (2000) 2.39
Superhelicity-driven homologous DNA pairing by yeast recombination factors Rad51 and Rad54. Mol Cell (2000) 2.28
Homologous recombination, but not DNA repair, is reduced in vertebrate cells deficient in RAD52. Mol Cell Biol (1998) 2.19
Mouse Rad54 affects DNA conformation and DNA-damage-induced Rad51 foci formation. Curr Biol (1999) 2.08
Interaction of human rad51 recombination protein with single-stranded DNA binding protein, RPA. Nucleic Acids Res (1998) 2.08
Characterization of null mutants of the RAD55 gene of Saccharomyces cerevisiae: effects of temperature, osmotic strength and mating type. Genetics (1987) 2.05
A Chinese hamster ovary cell line hypersensitive to ionizing radiation and deficient in repair replication. Mutat Res (1988) 2.00
Isolation and cross-sensitivity of X-ray-sensitive mutants of V79-4 hamster cells. Mutat Res (1987) 1.99
Rad54 protein is targeted to pairing loci by the Rad51 nucleoprotein filament. Mol Cell (2000) 1.98
Multiple genes at 17q23 undergo amplification and overexpression in breast cancer. Cancer Res (2000) 1.92
Functional interactions among yeast Rad51 recombinase, Rad52 mediator, and replication protein A in DNA strand exchange. J Biol Chem (2000) 1.91
Tailed duplex DNA is the preferred substrate for Rad51 protein-mediated homologous pairing. EMBO J (2000) 1.90
Mammalian recombination-repair genes XRCC2 and XRCC3 promote correct chromosome segregation. Nat Cell Biol (2000) 1.89
A surfeit of RAD51-like genes? Trends Genet (1999) 1.80
Xrcc2 is required for genetic stability, embryonic neurogenesis and viability in mice. EMBO J (2000) 1.77
The contribution of homologous recombination in preserving genome integrity in mammalian cells. Biochimie (1999) 1.74
Evidence for simultaneous protein interactions between human Rad51 paralogs. J Biol Chem (2000) 1.74
Isolation and characterization of RAD51C, a new human member of the RAD51 family of related genes. Nucleic Acids Res (1998) 1.70
The XRCC2 DNA repair gene from human and mouse encodes a novel member of the recA/RAD51 family. Nucleic Acids Res (1998) 1.60
Visualisation of human rad52 protein and its complexes with hRad51 and DNA. J Mol Biol (1998) 1.56
Reconstitution of the strand invasion step of double-strand break repair using human Rad51 Rad52 and RPA proteins. J Mol Biol (2000) 1.55
Human Dmc1 protein binds DNA as an octameric ring. Proc Natl Acad Sci U S A (1999) 1.53
Disruption of muREC2/RAD51L1 in mice results in early embryonic lethality which can Be partially rescued in a p53(-/-) background. Mol Cell Biol (1999) 1.53
Homologous DNA recombination in vertebrate cells. Proc Natl Acad Sci U S A (2001) 1.52
Identification of a novel human RAD51 homolog, RAD51B. Genomics (1997) 1.49
Allelic knockout of novel splice variants of human recombination repair gene RAD51B in t(12;14) uterine leiomyomas. Cancer Res (1999) 1.49
Identification, characterization, and genetic mapping of Rad51d, a new mouse and human RAD51/RecA-related gene. Genomics (1998) 1.42
Midgestation lethality in mice deficient for the RecA-related gene, Rad51d/Rad51l3. Genesis (2000) 1.38
The RAD51 family member, RAD51L3, is a DNA-stimulated ATPase that forms a complex with XRCC2. J Biol Chem (2000) 1.37
Heteroduplex formation by human Rad51 protein: effects of DNA end-structure, hRP-A and hRad52. J Mol Biol (1999) 1.35
The XRCC2 and XRCC3 repair genes are required for chromosome stability in mammalian cells. Mutat Res (1999) 1.33
A recombination repair gene of Schizosaccharomyces pombe, rhp57, is a functional homolog of the Saccharomyces cerevisiae RAD57 gene and is phylogenetically related to the human XRCC3 gene. Genetics (2000) 1.32
Isolation of human and mouse genes based on homology to REC2, a recombinational repair gene from the fungus Ustilago maydis. Proc Natl Acad Sci U S A (1997) 1.28
Isolation of novel human and mouse genes of the recA/RAD51 recombination-repair gene family. Nucleic Acids Res (1998) 1.27
Localization and dynamic relocalization of mammalian Rad52 during the cell cycle and in response to DNA damage. Curr Biol (1999) 1.23
hREC2, a RAD51-like gene, is disrupted by t(12;14) (q15;q24.1) in a uterine leiomyoma. Cancer Genet Cytogenet (1999) 0.91
HsRec2/Rad51L1, a protein influencing cell cycle progression, has protein kinase activity. Exp Cell Res (2000) 0.87
Role of BRCA2 in control of the RAD51 recombination and DNA repair protein. Mol Cell (2001) 5.59
Human Rad51 protein promotes ATP-dependent homologous pairing and strand transfer reactions in vitro. Cell (1996) 5.29
The Bloom's syndrome gene product promotes branch migration of holliday junctions. Proc Natl Acad Sci U S A (2000) 4.67
Purification and characterization of the human Rad51 protein, an analogue of E. coli RecA. EMBO J (1994) 4.55
Role of the human RAD51 protein in homologous recombination and double-stranded-break repair. Trends Biochem Sci (1998) 4.01
XPG endonuclease makes the 3' incision in human DNA nucleotide excision repair. Nature (1994) 3.93
Binding of double-strand breaks in DNA by human Rad52 protein. Nature (1999) 3.80
Synergistic actions of Rad51 and Rad52 in recombination and DNA repair. Nature (1998) 3.57
DNA end-joining catalyzed by human cell-free extracts. Proc Natl Acad Sci U S A (1998) 3.11
ATP-dependent branch migration of Holliday junctions promoted by the RuvA and RuvB proteins of E. coli. Cell (1992) 2.97
Role of RecA protein spiral filaments in genetic recombination. Nature (1984) 2.96
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Werner's syndrome protein (WRN) migrates Holliday junctions and co-localizes with RPA upon replication arrest. EMBO Rep (2000) 2.88
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Identification and purification of two distinct complexes containing the five RAD51 paralogs. Genes Dev (2001) 2.54
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Gross chromosomal rearrangements and genetic exchange between nonhomologous chromosomes following BRCA2 inactivation. Genes Dev (2000) 2.47
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The human Rad52 protein exists as a heptameric ring. Curr Biol (2000) 2.09
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Mouse Rad54 affects DNA conformation and DNA-damage-induced Rad51 foci formation. Curr Biol (1999) 2.08
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