Published in Nat Biotechnol on August 01, 2001
Chromosomal site-specific double-strand breaks are efficiently targeted for repair by oligonucleotides in yeast. Proc Natl Acad Sci U S A (2003) 2.75
Chromatin- and transcription-related factors repress transcription from within coding regions throughout the Saccharomyces cerevisiae genome. PLoS Biol (2008) 2.73
Break-induced replication is highly inaccurate. PLoS Biol (2011) 2.45
Recombineering with overlapping single-stranded DNA oligonucleotides: testing a recombination intermediate. Proc Natl Acad Sci U S A (2003) 2.11
Saccharomyces cerevisiae MutLalpha is a mismatch repair endonuclease. J Biol Chem (2007) 2.09
Function of a conserved checkpoint recruitment domain in ATRIP proteins. Mol Cell Biol (2007) 2.02
Hypermutability of damaged single-strand DNA formed at double-strand breaks and uncapped telomeres in yeast Saccharomyces cerevisiae. PLoS Genet (2008) 2.00
Complex genetic interactions in a quantitative trait locus. PLoS Genet (2006) 1.95
Polyploidy can drive rapid adaptation in yeast. Nature (2015) 1.87
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Differential transactivation by the p53 transcription factor is highly dependent on p53 level and promoter target sequence. Mol Cell Biol (2002) 1.83
Widespread impact of nonsense-mediated mRNA decay on the yeast intronome. Mol Cell (2008) 1.72
Conservative repair of a chromosomal double-strand break by single-strand DNA through two steps of annealing. Mol Cell Biol (2006) 1.71
Synthesis of DNA fragments in yeast by one-step assembly of overlapping oligonucleotides. Nucleic Acids Res (2009) 1.70
Structure of a yeast RNase III dsRBD complex with a noncanonical RNA substrate provides new insights into binding specificity of dsRBDs. Structure (2011) 1.69
Noncanonical DNA motifs as transactivation targets by wild type and mutant p53. PLoS Genet (2008) 1.67
Structural basis for recognition of the AGNN tetraloop RNA fold by the double-stranded RNA-binding domain of Rnt1p RNase III. Proc Natl Acad Sci U S A (2004) 1.66
Functional mutants of the sequence-specific transcription factor p53 and implications for master genes of diversity. Proc Natl Acad Sci U S A (2003) 1.63
Set3 HDAC mediates effects of overlapping noncoding transcription on gene induction kinetics. Cell (2012) 1.61
Transcription-associated mutagenesis in yeast is directly proportional to the level of gene expression and influenced by the direction of DNA replication. DNA Repair (Amst) (2007) 1.54
Defective break-induced replication leads to half-crossovers in Saccharomyces cerevisiae. Genetics (2008) 1.52
Single-stranded heteroduplex intermediates in lambda Red homologous recombination. BMC Mol Biol (2010) 1.51
Heme levels switch the function of Hap1 of Saccharomyces cerevisiae between transcriptional activator and transcriptional repressor. Mol Cell Biol (2007) 1.43
Introns regulate RNA and protein abundance in yeast. Genetics (2006) 1.39
Cotranscriptional recruitment of the pseudouridylsynthetase Cbf5p and of the RNA binding protein Naf1p during H/ACA snoRNP assembly. Mol Cell Biol (2005) 1.26
Non-Mendelian determinant [ISP+] in yeast is a nuclear-residing prion form of the global transcriptional regulator Sfp1. Proc Natl Acad Sci U S A (2010) 1.26
CRISPR/Cas9: a molecular Swiss army knife for simultaneous introduction of multiple genetic modifications in Saccharomyces cerevisiae. FEMS Yeast Res (2015) 1.25
The flexible loop of human FEN1 endonuclease is required for flap cleavage during DNA replication and repair. EMBO J (2002) 1.23
Gene-environment interactions at nucleotide resolution. PLoS Genet (2010) 1.16
Genetic dissection of complex traits in yeast: insights from studies of gene expression and other phenotypes in the BYxRM cross. Cold Spring Harb Symp Quant Biol (2009) 1.16
Coevolution within a transcriptional network by compensatory trans and cis mutations. Genome Res (2010) 1.16
An ER-peroxisome tether exerts peroxisome population control in yeast. EMBO J (2013) 1.15
Dissecting BAR domain function in the yeast Amphiphysins Rvs161 and Rvs167 during endocytosis. Mol Biol Cell (2010) 1.14
Alternative splicing of PTC7 in Saccharomyces cerevisiae determines protein localization. Genetics (2009) 1.14
PCR-based methods facilitate targeted gene manipulations and cloning procedures. Curr Genet (2003) 1.14
Targeted nucleotide repair of cyc1 mutations in Saccharomyces cerevisiae directed by modified single-stranded DNA oligonucleotides. Genetics (2003) 1.13
Genetic architecture of highly complex chemical resistance traits across four yeast strains. PLoS Genet (2012) 1.13
Dynamics of Rad9 chromatin binding and checkpoint function are mediated by its dimerization and are cell cycle-regulated by CDK1 activity. PLoS Genet (2010) 1.12
Yeast Rrp8p, a novel methyltransferase responsible for m1A 645 base modification of 25S rRNA. Nucleic Acids Res (2012) 1.12
From function to shape: a novel role of a formin in morphogenesis of the fungus Ashbya gossypii. Mol Biol Cell (2005) 1.09
Knocking out multigene redundancies via cycles of sexual assortment and fluorescence selection. Nat Methods (2011) 1.08
Novel nucleotide sequence motifs that produce hotspots of meiotic recombination in Schizosaccharomyces pombe. Genetics (2009) 1.07
Mispaired rNMPs in DNA are mutagenic and are targets of mismatch repair and RNases H. Nat Struct Mol Biol (2011) 1.06
Improving industrial yeast strains: exploiting natural and artificial diversity. FEMS Microbiol Rev (2014) 1.05
A single-strand specific lesion drives MMS-induced hyper-mutability at a double-strand break in yeast. DNA Repair (Amst) (2010) 1.03
An unusual transmembrane helix in the endoplasmic reticulum ubiquitin ligase Doa10 modulates degradation of its cognate E2 enzyme. J Biol Chem (2011) 1.02
Mutagenic inverted repeat assisted genome engineering (MIRAGE). Nucleic Acids Res (2008) 1.01
A general role of the DNA glycosylase Nth1 in the abasic sites cleavage step of base excision repair in Schizosaccharomyces pombe. Nucleic Acids Res (2004) 1.00
Yeast oligo-mediated genome engineering (YOGE). ACS Synth Biol (2013) 1.00
Implementation of the CRISPR-Cas9 system in fission yeast. Nat Commun (2014) 0.99
FRUIT, a scar-free system for targeted chromosomal mutagenesis, epitope tagging, and promoter replacement in Escherichia coli and Salmonella enterica. PLoS One (2012) 0.99
Genetic interactions involving five or more genes contribute to a complex trait in yeast. PLoS Genet (2014) 0.98
Site-specific genomic (SSG) and random domain-localized (RDL) mutagenesis in yeast. BMC Biotechnol (2004) 0.96
Essential role of nuclear localization for yeast Ulp2 SUMO protease function. Mol Biol Cell (2009) 0.95
Cotranslational transport of ABP140 mRNA to the distal pole of S. cerevisiae. EMBO J (2011) 0.94
A developmentally regulated translational control pathway establishes the meiotic chromosome segregation pattern. Genes Dev (2013) 0.94
Genetic re-engineering of Saccharomyces cerevisiae RAD51 leads to a significant increase in the frequency of gene repair in vivo. Nucleic Acids Res (2004) 0.94
Function and structural organization of Mot1 bound to a natural target promoter. J Biol Chem (2008) 0.93
A cotranscriptional model for 3'-end processing of the Saccharomyces cerevisiae pre-ribosomal RNA precursor. RNA (2004) 0.93
Replicative DNA polymerase δ but not ε proofreads errors in Cis and in Trans. PLoS Genet (2015) 0.92
The 50:50 method for PCR-based seamless genome editing in yeast. Yeast (2013) 0.92
An evaluation of high-throughput approaches to QTL mapping in Saccharomyces cerevisiae. Genetics (2013) 0.92
The Ecm11-Gmc2 complex promotes synaptonemal complex formation through assembly of transverse filaments in budding yeast. PLoS Genet (2013) 0.92
Higher-order genetic interactions and their contribution to complex traits. Trends Genet (2014) 0.92
Coincident resection at both ends of random, γ-induced double-strand breaks requires MRX (MRN), Sae2 (Ctp1), and Mre11-nuclease. PLoS Genet (2013) 0.92
Use of a ura5+-lys7+ cassette to construct unmarked gene knock-ins in Schizosaccharomyces pombe. Curr Genet (2011) 0.91
Transcriptional Derepression Uncovers Cryptic Higher-Order Genetic Interactions. PLoS Genet (2015) 0.89
Genetic mapping of MAPK-mediated complex traits Across S. cerevisiae. PLoS Genet (2015) 0.88
Calcineurin orchestrates dimorphic transitions, antifungal drug responses and host-pathogen interactions of the pathogenic mucoralean fungus Mucor circinelloides. Mol Microbiol (2015) 0.88
Cryptic transcription mediates repression of subtelomeric metal homeostasis genes. PLoS Genet (2011) 0.87
Yeast linker histone Hho1p is required for efficient RNA polymerase I processivity and transcriptional silencing at the ribosomal DNA. Proc Natl Acad Sci U S A (2008) 0.87
Yeast Tdh3 (glyceraldehyde 3-phosphate dehydrogenase) is a Sir2-interacting factor that regulates transcriptional silencing and rDNA recombination. PLoS Genet (2013) 0.86
Novel attributes of Hed1 affect dynamics and activity of the Rad51 presynaptic filament during meiotic recombination. J Biol Chem (2011) 0.86
The NatA acetyltransferase couples Sup35 prion complexes to the [PSI+] phenotype. Mol Biol Cell (2008) 0.86
Biotin starvation causes mitochondrial protein hyperacetylation and partial rescue by the SIRT3-like deacetylase Hst4p. Nat Commun (2015) 0.86
Variants in SUP45 and TRM10 underlie natural variation in translation termination efficiency in Saccharomyces cerevisiae. PLoS Genet (2011) 0.84
Transformation with oligonucleotides creating clustered changes in the yeast genome. PLoS One (2012) 0.84
Regulatory Rewiring in a Cross Causes Extensive Genetic Heterogeneity. Genetics (2015) 0.84
Diverse genetic architectures lead to the same cryptic phenotype in a yeast cross. Nat Commun (2016) 0.84
In vivo bypass of 8-oxodG. PLoS Genet (2013) 0.84
Limiting the extent of the RDN1 heterochromatin domain by a silencing barrier and Sir2 protein levels in Saccharomyces cerevisiae. Mol Cell Biol (2009) 0.83
Genetic basis of hidden phenotypic variation revealed by increased translational readthrough in yeast. PLoS Genet (2012) 0.83
Bacterial genome reduction using the progressive clustering of deletions via yeast sexual cycling. Genome Res (2015) 0.83
A new reversion assay for measuring all possible base pair substitutions in Saccharomyces cerevisiae. Genetics (2005) 0.83
Milestones in Candida albicans gene manipulation. Fungal Genet Biol (2011) 0.83
Novel PMS1 alleles preferentially affect the repair of primer strand loops during DNA replication. Mol Cell Biol (2005) 0.83
To nick or not to nick: comparison of I-SceI single- and double-strand break-induced recombination in yeast and human cells. PLoS One (2014) 0.83
P53 family members modulate the expression of PRODH, but not PRODH2, via intronic p53 response elements. PLoS One (2013) 0.83
Different roles of eukaryotic MutS and MutL complexes in repair of small insertion and deletion loops in yeast. PLoS Genet (2013) 0.82
The polymerase eta translesion synthesis DNA polymerase acts independently of the mismatch repair system to limit mutagenesis caused by 7,8-dihydro-8-oxoguanine in yeast. Mol Cell Biol (2009) 0.82
A genome-wide map of mitochondrial DNA recombination in yeast. Genetics (2014) 0.82
Mrd1p is required for release of base-paired U3 snoRNA within the preribosomal complex. Mol Cell Biol (2009) 0.82
Nuclease activity of Saccharomyces cerevisiae Mre11 functions in targeted nucleotide alteration. Appl Environ Microbiol (2003) 0.82
Distal chromatin structure influences local nucleosome positions and gene expression. Nucleic Acids Res (2012) 0.82
The complex genetic and molecular basis of a model quantitative trait. Mol Biol Cell (2015) 0.82
∆N-P63α and TA-P63α exhibit intrinsic differences in transactivation specificities that depend on distinct features of DNA target sites. Oncotarget (2014) 0.81
Functional residues on the surface of the N-terminal domain of yeast Pms1. DNA Repair (Amst) (2010) 0.81
Adeno-associated virus inverted terminal repeats stimulate gene editing. Gene Ther (2014) 0.81
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Multi-locus Genotypes Underlying Temperature Sensitivity in a Mutationally Induced Trait. PLoS Genet (2016) 0.80
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