Published in J Biol Chem on August 01, 2001
Ion channels and cancer. J Membr Biol (2005) 2.56
Low expression of chloride channel accessory 1 predicts a poor prognosis in colorectal cancer. Cancer (2015) 2.10
TMEM16A induces MAPK and contributes directly to tumorigenesis and cancer progression. Cancer Res (2012) 1.98
Volume-sensitive chloride channels involved in apoptotic volume decrease and cell death. J Membr Biol (2006) 1.68
Phenomics of cardiac chloride channels: the systematic study of chloride channel function in the heart. J Physiol (2009) 1.42
The role of CLCA proteins in inflammatory airway disease. Annu Rev Physiol (2009) 1.26
Clinical relevance of ion channels for diagnosis and therapy of cancer. J Membr Biol (2005) 1.26
The CLCA gene locus as a modulator of the gastrointestinal basic defect in cystic fibrosis. Hum Genet (2004) 1.14
hCLCA2 Is a p53-Inducible Inhibitor of Breast Cancer Cell Proliferation. Cancer Res (2009) 1.08
The Ca(2+) -activated Cl(-) channel, ANO1 (TMEM16A), is a double-edged sword in cell proliferation and tumorigenesis. Cancer Med (2014) 1.05
The transition from proliferation to differentiation in colorectal cancer is regulated by the calcium activated chloride channel A1. PLoS One (2013) 1.05
Comparative gene expression profiling analysis of urothelial carcinoma of the renal pelvis and bladder. BMC Med Genomics (2010) 1.03
Ion channels and membrane rafts in apoptosis. Pflugers Arch (2004) 0.99
Murine mCLCA6 is an integral apical membrane protein of non-goblet cell enterocytes and co-localizes with the cystic fibrosis transmembrane conductance regulator. J Histochem Cytochem (2008) 0.98
Molecular and functional analyses of two new calcium-activated chloride channel family members from mouse eye and intestine. J Biol Chem (2004) 0.95
Ion channels and apoptosis in cancer. Philos Trans R Soc Lond B Biol Sci (2014) 0.91
CLCA2, a target of the p53 family, negatively regulates cancer cell migration and invasion. Cancer Biol Ther (2012) 0.91
CLCA2 as a p53-inducible senescence mediator. Neoplasia (2012) 0.89
Acute exposure of apigenin induces hepatotoxicity in Swiss mice. PLoS One (2012) 0.86
Phenomics of cardiac chloride channels. Compr Physiol (2013) 0.86
Expression analysis of the CLCA gene family in mouse and human with emphasis on the nervous system. BMC Dev Biol (2009) 0.81
Progress in focus: recent advances in histochemistry and cell biology. Histochem Cell Biol (2002) 0.80
A protective mechanism against antibiotic-induced ototoxicity: role of prestin. PLoS One (2011) 0.78
NSAIDs modulate GABA-activated currents via Ca(2+)-activated Cl(-) channels in rat dorsal root ganglion neurons. Exp Ther Med (2016) 0.77
Prolactin and dexamethasone regulate second messenger-stimulated cl(-) secretion in mammary epithelia. J Signal Transduct (2012) 0.76
Stat3 modulates chloride channel accessory protein expression in normal and neoplastic mammary tissue. Cell Death Dis (2016) 0.75
Adenoviral-mediated pHyde gene transfer and cisplatin additively inhibit human prostate cancer growth by enhancing apoptosis. Prostate (2009) 0.75
CLCA splicing isoform associated with adhesion through β1-integrin and its scaffolding protein: specific expression in undifferentiated epithelial cells. J Biol Chem (2013) 0.75
CLCA1 suppresses colorectal cancer aggressiveness via inhibition of the Wnt/beta-catenin signaling pathway. Cell Commun Signal (2017) 0.75
Synthesis of cartilage matrix by mammalian chondrocytes in vitro. I. Isolation, culture characteristics, and morphology. J Cell Biol (1982) 1.81
Genomic cloning, molecular characterization, and functional analysis of human CLCA1, the first human member of the family of Ca2+-activated Cl- channel proteins. Genomics (1998) 1.56
Dynamics of neutrophil rolling over stimulated endothelium in vitro. Biophys J (1994) 1.55
Molecular cloning and transmembrane structure of hCLCA2 from human lung, trachea, and mammary gland. Am J Physiol (1999) 1.37
Molecular and functional characterization of a calcium-sensitive chloride channel from mouse lung. J Biol Chem (1998) 1.34
Tumor invasion and host extracellular matrix. Cancer Metastasis Rev (1983) 1.20
Mediation of lung metastasis of murine melanomas by a lung-specific endothelial cell adhesion molecule. Proc Natl Acad Sci U S A (1991) 1.17
Lung endothelial dipeptidyl peptidase IV promotes adhesion and metastasis of rat breast cancer cells via tumor cell surface-associated fibronectin. J Biol Chem (1998) 1.16
The breast cancer beta 4 integrin and endothelial human CLCA2 mediate lung metastasis. J Biol Chem (2001) 1.10
Tumorigenicity of human breast cancer is associated with loss of the Ca2+-activated chloride channel CLCA2. Cancer Res (1999) 1.10
Clinical and pathologic aspects of spontaneous canine prostate carcinoma: a retrospective analysis of 76 cases. Prostate (2000) 1.08
Cloning and characterization of lung-endothelial cell adhesion molecule-1 suggest it is an endothelial chloride channel. J Biol Chem (1997) 1.08
Ca(2+)-activated Cl(-) channels: a newly emerging anion transport family. Pflugers Arch (2001) 1.07
Correlation between numbers of desmosomes and the aggressiveness of transitional cell carcinoma in human urinary bladder. Cancer (1981) 1.05
Kinetics of glomerular visceral epithelial cell phagocytosis. Kidney Int (1978) 1.00
Senescence of aortic endothelial cells in culture: effects of basic fibroblast growth factor expression on cell phenotype, migration, and proliferation. J Cell Physiol (1993) 0.98
Adhesion-mediated gap junctional communication between lung-metastatatic cancer cells and endothelium. Invasion Metastasis (1995) 0.98
Cytoplasmic dye transfer between metastatic tumor cells and vascular endothelium. J Cell Biol (1991) 0.98
Molecular cloning and biochemical characterization of a truncated, secreted member of the human family of Ca2+-activated Cl- channels. Biochim Biophys Acta (1999) 0.96
The murine calcium-sensitive chloride channel (mCaCC) is widely expressed in secretory epithelia and in other select tissues. Histochem Cell Biol (1998) 0.94
Rotary replication of lens gap junction. J Ultrastruct Res (1982) 0.93
Desmosome ultrastructure and biological behavior of chemical carcinogen-induced urinary bladder carcinomas. Cancer Res (1978) 0.93
Lung endothelial dipeptidyl peptidase IV is an adhesion molecule for lung-metastatic rat breast and prostate carcinoma cells. J Cell Biol (1993) 0.92
Endothelial cell membrane vesicles in the study of organ preference of metastasis. Cancer Res (1991) 0.92
Inhibition of glomerular visceral epithelial cell endocytosis during nephrosis induced by puromycin aminonucleoside. Lab Invest (1984) 0.92
The isolation and characterization in vitro of normal epithelial cells, endothelial cells and fibroblasts from rat urinary bladder. Tissue Cell (1980) 0.91
Cell junctions and the biological behaviour of cancer. Ciba Found Symp (1987) 0.90
Synthesis of cartilage matrix by mammalian chondrocytes in vitro. II. Maintenance of collagen and proteoglycan phenotype. J Cell Biol (1982) 0.89
A new adhesion assay using buoyancy to remove non-adherent cells. J Immunol Methods (1995) 0.88
Morphological studies on the resistance of cartilage to invasion by osteosarcoma cells in vitro and in vivo. Cancer Res (1978) 0.88
The resistance of epithelia to vascularization: proteinase and endothelial cell growth inhibitory activities in urinary bladder epithelium. Tissue Cell (1982) 0.88
Blocking of lung endothelial cell adhesion molecule-1 (Lu-ECAM-1) inhibits murine melanoma lung metastasis. J Clin Invest (1992) 0.87
Truncated dipeptidyl peptidase IV is a potent anti-adhesion and anti-metastasis peptide for rat breast cancer cells. Invasion Metastasis (1998) 0.86
Malignant transformation of urinary bladder in humans and in N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide-exposed Fischer rats: ultrastructure of the major components of the permeability barrier. Cancer Res (1977) 0.85
Generation of monoclonal antibodies directed against organ-specific endothelial cell surface determinants. J Histochem Cytochem (1991) 0.85
An ultrastructural study of acinic cell carcinomas of the canine pancreas. Am J Pathol (1978) 0.84
Pathology of superficial bladder cancer with emphasis on carcinoma in situ. Urology (1985) 0.84
Synthesis of cartilage matrix by mammalian chondrocytes in vitro. III. Effects of ascorbate. J Cell Biol (1984) 0.84
Endocytosis: a property of the glomerular visceral epithelial cell. Nephron (1978) 0.84
Migrating endothelial cells are distinctly hyperglycosylated and express specific migration-associated cell surface glycoproteins. J Cell Biol (1992) 0.83
Impairment of glomerular clearance of macroaggregates in immune complex glomerulonephritis. Kidney Int (1982) 0.83
Ultrastructure of cell junctions in FANFT-induced urothelial tumors in urinary bladder of Fischer rats. Lab Invest (1977) 0.83
Intracytoplasmic lumina in bladder carcinomas. Hum Pathol (1979) 0.83
Modulation of endothelial cell surface glycoconjugate expression by organ-derived biomatrices. Exp Cell Res (1991) 0.83
Regulation of tumor invasion by cartilage-derived anti-invasion factor in vitro. J Natl Cancer Inst (1981) 0.83
Evidence of glomerular epithelial cell endocytosis in vitro. Lab Invest (1981) 0.82
Lu-ECAM-1-mediated adhesion of melanoma cells to endothelium under conditions of flow. Int J Cancer (1996) 0.82
Isoantigens A, B and H in urinary bladder carcinomas following radiotherapy. Cancer (1978) 0.82
Quantitative analysis of autocrine-regulated, matrix-induced, and tumor cell-stimulated endothelial cell migration using a silicon template compartmentalization technique. Exp Cell Res (1992) 0.81
Correlation of fibrinolytic activity with invasion and metastasis of R3230 AC rat mammary carcinoma cell lines. Invasion Metastasis (1987) 0.80
Carcinoma in situ: comments on the pathobiology of a paradox. Urol Clin North Am (1980) 0.80
Topography and numerical densities of intramembrane particles in chemical carcinogen-induced urinary bladder carcinomas in Fischer rats. Lab Invest (1978) 0.79
Tumor invasion and its local regulation. Urology (1984) 0.79
Carcinogenicity of CoCrMo (F-75) implants in the rat. J Biomed Mater Res (1996) 0.78
Alterations of intercellular junctions in acinic cell carcinoma of the canine pancreas. Virchows Arch B Cell Pathol (1978) 0.78
Correlations between cell surface protease activities and abnormalities of occludens junctions in rat bladder carcinoma in vitro. Cancer Res (1982) 0.78
Is the Fischer 344/CRJ rat a protein-knock-out model for dipeptidyl peptidase IV-mediated lung metastasis of breast cancer? Clin Exp Metastasis (1999) 0.78
Inhibition of neovascularization by a cartilage factor. Ciba Found Symp (1983) 0.78
Cellular changes in rat urinary bladder carcinomas induced by FANFT: a quantitative electron microscopic analysis. J Urol (1983) 0.77
Proteoglycan synthesis by normal and neoplastic human transitional epithelial cells. J Cell Biochem (1990) 0.77
Flow cytometric analysis of heterogeneity in blood group-related antigen expression in a human urinary bladder carcinoma cell line, 647V. Cancer Res (1985) 0.76
Lu-ECAM-1 and DPP IV in lung metastasis. Curr Top Microbiol Immunol (1996) 0.75
Correlation between the lung distribution patterns of Lu-ECAM-1 and melanoma experimental metastases. Int J Cancer (1993) 0.75
Epithelial injury by cystoscopy fluids. Semin Oncol (1979) 0.75
[Interstitial cell adenoma of the hypophysis with Cushing-like symptomatology in the horse]. Vet Pathol (1974) 0.75
Surface charge distribution in normal and transformed rat bladder epithelial cells in vitro. Lab Invest (1985) 0.75
Intercellular junctions in tumor diagnosis. Ultrastruct Pathol (1984) 0.75
Development of an in vitro and in vivo epithelial tumor model for the study of invasion. Cancer Res (1980) 0.75
Association of asymmetric unit membrane plaque formation in the urinary bladder of adult humans with therapeutic radiation. Experientia (1977) 0.75
Association of therapeutic radiation with golgi complex hypertrophy in human urinary bladder carcinomas: quantitative electron microscopy studies. Ultrastruct Pathol (2006) 0.75
Connective tissue degradation by invasive rat bladder carcinomas: action of nonspecific proteinases on collagenous matrices. Cancer Res (1986) 0.75
In vitro determination of tumor invasiveness using extracted hyaline cartilage. Cancer Res (1981) 0.75
Structure of gap junctions in cultures of normal and neoplastic bladder epithelial cells. Experientia (1981) 0.75
Intercellular junctions in FANFT-induced carcinomas of rat urinary bladder in tissue culture: in situ thin-section, freeze-fracture, and scanning electron microscopy studies. J Microsc (1979) 0.75
Induction of reversible changes in cell-surface glycoconjugates and lung colonization potential by 13-cis retinoic acid. J Cell Biochem (1988) 0.75
Ultrastructure of tight junctions in prostaglandin-exposed rat stomach. Dig Dis Sci (1986) 0.75
Clustering of the human CLCA gene family on the short arm of chromosome 1 (1p22-31). Genome (1999) 0.75
Inhibition of tumor invasion by tissue-derived proteinase inhibitors. Monogr Pathol (1986) 0.75
Modulation of the metastatic phenotype by 13-cis-retinoic acid. J Natl Cancer Inst (1987) 0.75