Published in J Membr Biol on June 01, 2005
Is cancer triggered by altered signalling of nicotinic acetylcholine receptors? Nat Rev Cancer (2009) 2.92
Genome-wide functional analysis of human cell-cycle regulators. Proc Natl Acad Sci U S A (2006) 2.31
Voltage-gated Na+ channel SCN5A is a key regulator of a gene transcriptional network that controls colon cancer invasion. Cancer Res (2010) 2.01
An unexpected role for ion channels in brain tumor metastasis. Exp Biol Med (Maywood) (2008) 2.00
The tumor suppressor eIF3e mediates calcium-dependent internalization of the L-type calcium channel CaV1.2. Neuron (2007) 1.89
LRRC26 auxiliary protein allows BK channel activation at resting voltage without calcium. Nature (2010) 1.89
Bioelectric controls of cell proliferation: ion channels, membrane voltage and the cell cycle. Cell Cycle (2009) 1.88
Physiological roles and diseases of Tmem16/Anoctamin proteins: are they all chloride channels? Acta Pharmacol Sin (2011) 1.64
Bioelectric mechanisms in regeneration: Unique aspects and future perspectives. Semin Cell Dev Biol (2009) 1.56
Calcium-dependent chloride conductance in epithelia: is there a contribution by Bestrophin? Pflugers Arch (2007) 1.47
Prevention and treatment of colon cancer by peroral administration of HAMLET (human α-lactalbumin made lethal to tumour cells). Gut (2013) 1.45
ANO1 amplification and expression in HNSCC with a high propensity for future distant metastasis and its functions in HNSCC cell lines. Br J Cancer (2010) 1.38
Transient receptor potential melastatin 7-like current in human head and neck carcinoma cells: role in cell proliferation. Cancer Res (2007) 1.35
Membrane potential and cancer progression. Front Physiol (2013) 1.35
Anoctamins. Pflugers Arch (2011) 1.29
Enhanced expression of ANO1 in head and neck squamous cell carcinoma causes cell migration and correlates with poor prognosis. PLoS One (2012) 1.26
Morphogenetic fields in embryogenesis, regeneration, and cancer: non-local control of complex patterning. Biosystems (2012) 1.23
Modulation of potassium channel function confers a hyperproliferative invasive phenotype on embryonic stem cells. Proc Natl Acad Sci U S A (2008) 1.22
K+ channel expression in human breast cancer cells: involvement in cell cycle regulation and carcinogenesis. J Membr Biol (2007) 1.19
Transmembrane potential of GlyCl-expressing instructor cells induces a neoplastic-like conversion of melanocytes via a serotonergic pathway. Dis Model Mech (2010) 1.17
Increased TMEM16A-encoded calcium-activated chloride channel activity is associated with pulmonary hypertension. Am J Physiol Cell Physiol (2012) 1.15
Loss of breast epithelial marker hCLCA2 promotes epithelial-to-mesenchymal transition and indicates higher risk of metastasis. Oncogene (2011) 1.14
Inhibition of T-type Ca²⁺ channels by endostatin attenuates human glioblastoma cell proliferation and migration. Br J Pharmacol (2012) 1.11
KCa3.1 channels are involved in the infiltrative behavior of glioblastoma in vivo. Cell Death Dis (2013) 1.10
Ion channels as targets for cancer therapy. Int J Physiol Pathophysiol Pharmacol (2011) 1.10
Role of Kir4.1 channels in growth control of glia. Glia (2007) 1.09
Reprogramming cells and tissue patterning via bioelectrical pathways: molecular mechanisms and biomedical opportunities. Wiley Interdiscip Rev Syst Biol Med (2013) 1.08
hCLCA2 Is a p53-Inducible Inhibitor of Breast Cancer Cell Proliferation. Cancer Res (2009) 1.08
Voltage-gated sodium channels and metastatic disease. Channels (Austin) (2012) 1.05
Therapeutic potential for phenytoin: targeting Na(v)1.5 sodium channels to reduce migration and invasion in metastatic breast cancer. Breast Cancer Res Treat (2012) 1.05
Role of anoctamins in cancer and apoptosis. Philos Trans R Soc Lond B Biol Sci (2014) 1.04
Expression profiling of ion channel genes predicts clinical outcome in breast cancer. Mol Cancer (2013) 1.03
Transmembrane voltage potential is an essential cellular parameter for the detection and control of tumor development in a Xenopus model. Dis Model Mech (2013) 1.02
The voltage-dependent K(+) channels Kv1.3 and Kv1.5 in human cancer. Front Physiol (2013) 1.00
Disruption of transient receptor potential canonical channel 1 causes incomplete cytokinesis and slows the growth of human malignant gliomas. Glia (2010) 0.99
Identification of a posttranslational mechanism for the regulation of hERG1 K+ channel expression and hERG1 current density in tumor cells. Mol Cell Biol (2008) 0.99
Glioma-specific cation conductance regulates migration and cell cycle progression. J Biol Chem (2011) 0.96
Ion channels expression and function are strongly modified in solid tumors and vascular malformations. J Transl Med (2016) 0.96
Role of KCNMA1 in breast cancer. PLoS One (2012) 0.94
Molecular simulations of ion channels: a quantum chemist's perspective. J Gen Physiol (2010) 0.94
A large-conductance (BK) potassium channel subtype affects both growth and mineralization of human osteoblasts. Am J Physiol Cell Physiol (2009) 0.92
Carbon monoxide mediates the anti-apoptotic effects of heme oxygenase-1 in medulloblastoma DAOY cells via K+ channel inhibition. J Biol Chem (2012) 0.92
Ion channels and apoptosis in cancer. Philos Trans R Soc Lond B Biol Sci (2014) 0.91
Intracellular chloride regulates the G(1)/S cell cycle progression in gastric cancer cells. World J Gastrointest Oncol (2011) 0.91
HERG1 functions as an oncogene in pancreatic cancer and is downregulated by miR-96. Oncotarget (2014) 0.90
Expression and prognostic roles of Eag1 in resected esophageal squamous cell carcinomas. Dig Dis Sci (2007) 0.90
Endogenous Voltage Potentials and the Microenvironment: Bioelectric Signals that Reveal, Induce and Normalize Cancer. J Clin Exp Oncol (2013) 0.90
Cystic fibrosis as a bowel cancer syndrome and the potential role of CK2. Mol Cell Biochem (2008) 0.89
Sodium ion channel mutations in glioblastoma patients correlate with shorter survival. Mol Cancer (2011) 0.89
Activity of BK(Ca) channel is modulated by membrane cholesterol content and association with Na+/K+-ATPase in human melanoma IGR39 cells. J Biol Chem (2010) 0.88
Impact of AtNHX1, a vacuolar Na+/H+ antiporter, upon gene expression during short- and long-term salt stress in Arabidopsis thaliana. BMC Plant Biol (2007) 0.88
Involvement of Transient Receptor Potential Melastatin 7 Channels in Sophorae Radix-induced Apoptosis in Cancer Cells: Sophorae Radix and TRPM7. J Pharmacopuncture (2012) 0.87
K(+) channels and cell cycle progression in tumor cells. Front Physiol (2013) 0.87
Expression and Role of the Intermediate-Conductance Calcium-Activated Potassium Channel KCa3.1 in Glioblastoma. J Signal Transduct (2012) 0.87
Unique biology of gliomas: challenges and opportunities. Trends Neurosci (2012) 0.87
Ion channel gene expression in lung adenocarcinoma: potential role in prognosis and diagnosis. PLoS One (2014) 0.87
Dynamic regulation of RNA editing of ion channels and receptors in the mammalian nervous system. Mol Brain (2009) 0.85
Rectal forceps biopsy procedure in cystic fibrosis: technical aspects and patients perspective for clinical trials feasibility. BMC Gastroenterol (2013) 0.85
Function of chloride intracellular channel 1 in gastric cancer cells. World J Gastroenterol (2012) 0.84
Hypothyroidism of gene-targeted mice lacking Kcnq1. Pflugers Arch (2010) 0.84
Kv3.4 potassium channel-mediated electrosignaling controls cell cycle and survival of irradiated leukemia cells. Pflugers Arch (2013) 0.84
Single Cell Electrical Characterization Techniques. Int J Mol Sci (2015) 0.83
Cellular physiological approach for treatment of gastric cancer. World J Gastroenterol (2014) 0.83
Prognostic significance of hERG1 expression in gastric cancer. Dig Dis Sci (2009) 0.83
CACNA2D2 promotes tumorigenesis by stimulating cell proliferation and angiogenesis. Oncogene (2015) 0.82
Role of the Na ⁺/K ⁺/2Cl⁻ cotransporter NKCC1 in cell cycle progression in human esophageal squamous cell carcinoma. World J Gastroenterol (2014) 0.82
Upregulation of colonic ion channels in APC ( Min/+ ) mice. Pflugers Arch (2008) 0.82
Reduced Kv1.3 potassium channel expression in human prostate cancer. J Membr Biol (2007) 0.82
Gene expression profile of esophageal cancer in North East India by cDNA microarray analysis. World J Gastroenterol (2007) 0.82
Altered expression of two-pore domain potassium (K2P) channels in cancer. PLoS One (2013) 0.82
Functional coupling between large-conductance potassium channels and Cav3.2 voltage-dependent calcium channels participates in prostate cancer cell growth. Biol Open (2013) 0.81
Triazacryptand-based fluorescent sensors for extracellular and intracellular K+ sensing. Biomaterials (2011) 0.81
A unifying mechanism for cancer cell death through ion channel activation by HAMLET. PLoS One (2013) 0.81
The Flatworm Macrostomum lignano Is a Powerful Model Organism for Ion Channel and Stem Cell Research. Stem Cells Int (2012) 0.81
Transmembrane voltage potential of somatic cells controls oncogene-mediated tumorigenesis at long-range. Oncotarget (2014) 0.81
A comment on ion channels as pharmacological targets in oncology. J Gen Physiol (2008) 0.81
The K-Cl cotransporter KCC3 as an independent prognostic factor in human esophageal squamous cell carcinoma. Biomed Res Int (2014) 0.80
Genome-wide analysis reveals conserved transcriptional responses downstream of resting potential change in Xenopus embryos, axolotl regeneration, and human mesenchymal cell differentiation. Regeneration (Oxf) (2015) 0.80
Network-based analysis of calcium-binding protein genes identifies Grp94 as a target in human oral carcinogenesis. Br J Cancer (2007) 0.79
Blockade of voltage-gated sodium channels inhibits invasion of endocrine-resistant breast cancer cells. Int J Oncol (2015) 0.79
Increased voltage-dependent K(+) channel Kv1.3 and Kv1.5 expression correlates with leiomyosarcoma aggressiveness. Oncol Lett (2012) 0.79
The intermediate conductance Ca2+-activated K+ channel inhibitor TRAM-34 stimulates proliferation of breast cancer cells via activation of oestrogen receptors. Br J Pharmacol (2009) 0.79
The TREK2 Channel Is Involved in the Proliferation of 253J Cell, a Human Bladder Carcinoma Cell. Korean J Physiol Pharmacol (2013) 0.79
Low-voltage-activated T-type Ca2+ channel inhibitors as new tools in the treatment of glioblastoma: the role of endostatin. Pflugers Arch (2014) 0.79
Inhibition of epidermal growth factor signaling by the cardiac glycoside ouabain in medulloblastoma. Cancer Med (2014) 0.78
Potential Roles of Amiloride-Sensitive Sodium Channels in Cancer Development. Biomed Res Int (2016) 0.78
Low-dose photon irradiation alters cell differentiation via activation of hIK channels. Pflugers Arch (2014) 0.77
New Trends in Cancer Therapy: Targeting Ion Channels and Transporters. Pharmaceuticals (Basel) (2010) 0.77
Nuclear localization and functional characteristics of voltage-gated potassium channel Kv1.3. J Biol Chem (2015) 0.77
Up-Regulatory Effects of Curcumin on Large Conductance Ca2+-Activated K+ Channels. PLoS One (2015) 0.77
Cytotoxic Effects of two Iranian Scorpions Odontobuthusdoriae and Bothutus saulcyi on Five Human Cultured Cell lines and Fractions of Toxic Venom. Iran J Pharm Res (2012) 0.77
Ion transporters in brain tumors. Curr Med Chem (2015) 0.77
X-ray irradiation activates K+ channels via H2O2 signaling. Sci Rep (2015) 0.77
Bladder cancer and urothelial impairment: the role of TRPV1 as potential drug target. Biomed Res Int (2014) 0.76
Expression and localization of TASK-1, -2 and -3 channels in MG63 human osteoblast-like cells. Oncol Lett (2012) 0.76
Down-Regulation of ClC-3 Expression Reduces Epidermal Stem Cell Migration by Inhibiting Volume-Activated Chloride Currents. J Membr Biol (2016) 0.76
Role of aquaporins in cell proliferation: What else beyond water permeability? Channels (Austin) (2016) 0.76
Efficacy of a hypotonic treatment for peritoneal dissemination from gastric cancer cells: an in vivo evaluation. Biomed Res Int (2014) 0.76
Cysteines control the N- and C-linker-dependent gating of KCNH1 potassium channels. Biochim Biophys Acta (2012) 0.76
Transcriptional analysis of the conidiation pattern shift of the entomopathogenic fungus Metarhizium acridum in response to different nutrients. BMC Genomics (2016) 0.75
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Targeting effector memory T cells with a selective peptide inhibitor of Kv1.3 channels for therapy of autoimmune diseases. Mol Pharmacol (2005) 2.08
Receptor-mediated control of regulatory volume decrease (RVD) and apoptotic volume decrease (AVD). J Physiol (2001) 2.08
Intracellular K+ suppresses the activation of apoptosis in lymphocytes. J Biol Chem (1997) 2.06
Voltage-gated sodium channel expression and potentiation of human breast cancer metastasis. Clin Cancer Res (2005) 1.99
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Modulation of glioma cell migration and invasion using Cl(-) and K(+) ion channel blockers. J Neurosci (1999) 1.89
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Genomic amplification and oncogenic properties of the KCNK9 potassium channel gene. Cancer Cell (2003) 1.76
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hSK4/hIK1, a calmodulin-binding KCa channel in human T lymphocytes. Roles in proliferation and volume regulation. J Biol Chem (1999) 1.59
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Selective blockade of the intermediate-conductance Ca2+-activated K+ channel suppresses proliferation of microvascular and macrovascular endothelial cells and angiogenesis in vivo. Arterioscler Thromb Vasc Biol (2005) 1.53
Roles of K+ channels in regulating tumour cell proliferation and apoptosis. Pflugers Arch (2004) 1.53
Activation of K+ channels: an essential pathway in programmed cell death. Am J Physiol Lung Cell Mol Physiol (2004) 1.51
Functional and molecular identification of intermediate-conductance Ca(2+)-activated K(+) channels in breast cancer cells: association with cell cycle progression. Am J Physiol Cell Physiol (2004) 1.49
herg1 gene and HERG1 protein are overexpressed in colorectal cancers and regulate cell invasion of tumor cells. Cancer Res (2004) 1.49
Differential expression of volume-regulated anion channels during cell cycle progression of human cervical cancer cells. J Physiol (2000) 1.46
Blockage of intermediate-conductance Ca2+-activated K+ channels inhibit human pancreatic cancer cell growth in vitro. Mol Pharmacol (2004) 1.44
HERG K+ channel, a regulator of tumor cell apoptosis and proliferation. Cancer Res (2002) 1.43
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Ether a go-go potassium channels as human cervical cancer markers. Cancer Res (2004) 1.41
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Blocking swelling-activated chloride current inhibits mouse liver cell proliferation. J Physiol (2001) 1.28
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