Published in Cytokine Growth Factor Rev on December 01, 2001
Patterning a complex organ: branching morphogenesis and nephron segmentation in kidney development. Dev Cell (2010) 3.78
Retracted Neutralizing aptamers from whole-cell SELEX inhibit the RET receptor tyrosine kinase. PLoS Biol (2005) 2.77
Ret-dependent cell rearrangements in the Wolffian duct epithelium initiate ureteric bud morphogenesis. Dev Cell (2009) 1.81
GDNF rescues hyperglycemia-induced diabetic enteric neuropathy through activation of the PI3K/Akt pathway. J Clin Invest (2006) 1.77
Perineural invasion and associated pain in pancreatic cancer. Nat Rev Cancer (2011) 1.64
Etv4 and Etv5 are required downstream of GDNF and Ret for kidney branching morphogenesis. Nat Genet (2009) 1.55
Critical and distinct roles for key RET tyrosine docking sites in renal development. Genes Dev (2006) 1.54
A targeting mutation of tyrosine 1062 in Ret causes a marked decrease of enteric neurons and renal hypoplasia. Mol Cell Biol (2004) 1.44
Screening for PTB domain binding partners and ligand specificity using proteome-derived NPXY peptide arrays. Mol Cell Biol (2006) 1.41
Kidney development in the absence of Gdnf and Spry1 requires Fgf10. PLoS Genet (2010) 1.40
Interstitial Cajal-like cells in human gallbladder. J Mol Histol (2007) 1.38
Molecular pathology of thyroid cancer: diagnostic and clinical implications. Best Pract Res Clin Endocrinol Metab (2008) 1.31
The role of Cdk5 in neuroendocrine thyroid cancer. Cancer Cell (2013) 1.30
Nephric duct insertion is a crucial step in urinary tract maturation that is regulated by a Gata3-Raldh2-Ret molecular network in mice. Development (2011) 1.29
Characterization of fetal and postnatal enteric neuronal cell lines with improvement in intestinal neural function. Gastroenterology (2008) 1.27
Phosphotyrosine 1062 is critical for the in vivo activity of the Ret9 receptor tyrosine kinase isoform. Mol Cell Biol (2005) 1.23
The neurotrophic factor artemin promotes pancreatic cancer invasion. Ann Surg (2006) 1.22
Exomic sequencing of medullary thyroid cancer reveals dominant and mutually exclusive oncogenic mutations in RET and RAS. J Clin Endocrinol Metab (2012) 1.21
Genetic controls and cellular behaviors in branching morphogenesis of the renal collecting system. Wiley Interdiscip Rev Dev Biol (2013) 1.19
Pathobiology of dynorphins in trauma and disease. Front Biosci (2005) 1.17
Functional RET G691S polymorphism in cutaneous malignant melanoma. Oncogene (2009) 1.14
Deletion of Frs2alpha from the ureteric epithelium causes renal hypoplasia. Am J Physiol Renal Physiol (2009) 1.12
Cell-specific aptamers for targeted therapies. Methods Mol Biol (2009) 1.11
Diabetic gastrointestinal motility disorders and the role of enteric nervous system: current status and future directions. Neurogastroenterol Motil (2014) 1.09
GDNF/Ret signaling and renal branching morphogenesis: From mesenchymal signals to epithelial cell behaviors. Organogenesis (2011) 1.08
Vitamin A facilitates enteric nervous system precursor migration by reducing Pten accumulation. Development (2010) 1.07
c-Ret-mediated hearing loss in mice with Hirschsprung disease. Proc Natl Acad Sci U S A (2010) 1.07
RET/PTC1-driven neoplastic transformation and proinvasive phenotype of human thyrocytes involve Met induction and beta-catenin nuclear translocation. Neoplasia (2009) 1.04
Solid tumors associated with multiple endocrine neoplasias. Cancer Genet Cytogenet (2010) 1.04
A Drosophila model of multiple endocrine neoplasia type 2. Genetics (2005) 1.03
c-RET molecule in malignant melanoma from oncogenic RET-carrying transgenic mice and human cell lines. PLoS One (2010) 1.00
The transcription factors Etv4 and Etv5 mediate formation of the ureteric bud tip domain during kidney development. Development (2010) 0.99
Motor neuron trophic factors: therapeutic use in ALS? Brain Res Rev (2010) 0.98
Hypoxia-inducible factor signaling in pheochromocytoma: turning the rudder in the right direction. J Natl Cancer Inst (2013) 0.98
Alimentary tract innervation deficits and dysfunction in mice lacking GDNF family receptor alpha2. J Clin Invest (2003) 0.96
Identification of RET gene fusion by exon array analyses in "pan-negative" lung cancer from never smokers. Cell Res (2012) 0.96
The bidirectional interation between pancreatic cancer and diabetes. World J Surg Oncol (2012) 0.95
An immunoprotective privilege of corneal epithelial stem cells against Th17 inflammatory stress by producing glial cell-derived neurotrophic factor. Stem Cells (2010) 0.95
Novel role of neuronal Ca2+ sensor-1 as a survival factor up-regulated in injured neurons. J Cell Biol (2006) 0.95
Organotypic specificity of key RET adaptor-docking sites in the pathogenesis of neurocristopathies and renal malformations in mice. J Clin Invest (2010) 0.95
Trophic factor expression in phrenic motor neurons. Respir Physiol Neurobiol (2008) 0.93
Neurotrophin and GDNF family ligand receptor expression in vagal sensory nerve subtypes innervating the adult guinea pig respiratory tract. Am J Physiol Lung Cell Mol Physiol (2011) 0.91
Characterization of gene expression induced by RET with MEN2A or MEN2B mutation. Am J Pathol (2002) 0.91
The soluble ectodomain of RetC634Y inhibits both the wild-type and the constitutively active Ret. Biochem J (2003) 0.90
Expression of glial cell-derived neurotrophic factor and its receptor in the stem-cell-containing human limbal epithelium. Br J Ophthalmol (2008) 0.90
Retinoic acid upregulates ret and induces chain migration and population expansion in vagal neural crest cells to colonise the embryonic gut. PLoS One (2013) 0.90
QTL mapping of leukocyte telomere length in American Indians: the Strong Heart Family Study. Aging (Albany NY) (2013) 0.89
Artemin, a glial cell line-derived neurotrophic factor family member, induces TRPM8-dependent cold pain. J Neurosci (2013) 0.88
Molecular pathogenesis of MEN2-associated tumors. Fam Cancer (2005) 0.88
Lower urinary tract development and disease. Wiley Interdiscip Rev Syst Biol Med (2013) 0.87
Rap1GAP interacts with RET and suppresses GDNF-induced neurite outgrowth. Cell Res (2010) 0.87
Inflammation in thyroid oncogenesis. Am J Cancer Res (2012) 0.87
The important roles of RET, VEGFR2 and the RAF/MEK/ERK pathway in cancer treatment with sorafenib. Acta Pharmacol Sin (2012) 0.85
VEGF-A165 potently induces human blood-nerve barrier endothelial cell proliferation, angiogenesis, and wound healing in vitro. Cell Mol Neurobiol (2013) 0.85
Epigenetic modifications and self-renewal regulation of mouse germline stem cells. Cell Res (2011) 0.83
Wrecked regulation of intrinsically disordered proteins in diseases: pathogenicity of deregulated regulators. Front Mol Biosci (2014) 0.82
Prognostic molecular biomarkers for cutaneous malignant melanoma. J Surg Oncol (2011) 0.82
Sustained delivery of VEGF maintains innervation and promotes reperfusion in ischemic skeletal muscles via NGF/GDNF signaling. Mol Ther (2014) 0.82
Receptor tyrosine kinases in kidney development. J Signal Transduct (2011) 0.82
HSV-mediated transfer of artemin overcomes myelin inhibition to improve outcome after spinal cord injury. Mol Ther (2009) 0.82
Activated RET and ROS: two new driver mutations in lung adenocarcinoma. Transl Lung Cancer Res (2013) 0.81
Transgene-mediated GDNF expression enhances synaptic connectivity and GABA transmission to improve functional outcome after spinal cord contusion. J Neurochem (2010) 0.81
Medullary thyroid carcinoma: molecular signaling pathways and emerging therapies. J Thyroid Res (2011) 0.81
Unconventional functions of microtubule motors. Arch Biochem Biophys (2012) 0.79
GDNF-inducible zinc finger protein 1 is a sequence-specific transcriptional repressor that binds to the HOXA10 gene regulatory region. Nucleic Acids Res (2005) 0.79
HSP90 inhibition blocks ERBB3 and RET phosphorylation in myxoid/round cell liposarcoma and causes massive cell death in vitro and in vivo. Oncotarget (2016) 0.78
RET/PTC fusion gene rearrangements in Japanese thyroid carcinomas. Eur Arch Otorhinolaryngol (2004) 0.78
Prognostic gene signature identification using causal structure learning: applications in kidney cancer. Cancer Inform (2015) 0.77
Prophylactic thyroidectomy in multiple endocrine neoplasia: the impact of molecular mechanisms of RET proto-oncogene. Langenbecks Arch Surg (2003) 0.77
Thyroid Cancer: Role of RET and Beyond. Eur Thyroid J (2012) 0.76
GDNF-independent ureteric budding: role of PI3K-independent activation of AKT and FOSB/JUN/AP-1 signaling. Biol Open (2013) 0.76
Genetics of Vesicoureteral Reflux. Curr Genomics (2016) 0.75
Mutational dichotomy in desmoplastic malignant melanoma corroborated by multigene panel analysis. Mod Pathol (2015) 0.75
NEDL2 regulates enteric nervous system and kidney development in its Nedd8 ligase activity-dependent manner. Oncotarget (2016) 0.75
Review. Gastroenterol Hepatol (N Y) (2007) 0.75
Neurotrophic Factors NGF, GDNF and NTN Selectively Modulate HSV1 and HSV2 Lytic Infection and Reactivation in Primary Adult Sensory and Autonomic Neurons. Pathogens (2017) 0.75
Mosaic analysis of cell rearrangements during ureteric bud branching in dissociated/reaggregated kidney cultures and in vivo. Dev Dyn (2016) 0.75
Adjuvant neurotrophic factors in peripheral nerve repair with chondroitin sulfate proteoglycan-reduced acellular nerve allografts. J Surg Res (2014) 0.75
In Vitro Propagation and Branching Morphogenesis from Single Ureteric Bud Cells. Stem Cell Reports (2017) 0.75
Targeting tumor-associated macrophages to combat pancreatic cancer. Oncotarget (2016) 0.75
Identification of a novel variant of the RET proto-oncogene in a novel family with Hirschsprung's disease. Pediatr Surg Int (2017) 0.75