Published in Mod Pathol on March 13, 2015
Melanoma subtypes demonstrate distinct PD-L1 expression profiles. Lab Invest (2017) 0.75
Improved survival with vemurafenib in melanoma with BRAF V600E mutation. N Engl J Med (2011) 45.46
ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data. Nucleic Acids Res (2010) 43.51
Predicting the effects of coding non-synonymous variants on protein function using the SIFT algorithm. Nat Protoc (2009) 38.62
A program for annotating and predicting the effects of single nucleotide polymorphisms, SnpEff: SNPs in the genome of Drosophila melanogaster strain w1118; iso-2; iso-3. Fly (Austin) (2012) 20.08
Mutational evolution in a lobular breast tumour profiled at single nucleotide resolution. Nature (2009) 18.08
Diverse somatic mutation patterns and pathway alterations in human cancers. Nature (2010) 10.83
COSMIC: exploring the world's knowledge of somatic mutations in human cancer. Nucleic Acids Res (2014) 10.77
Frequent somatic mutations of GNAQ in uveal melanoma and blue naevi. Nature (2008) 8.42
Somatic activation of KIT in distinct subtypes of melanoma. J Clin Oncol (2006) 7.76
Mutations in GNA11 in uveal melanoma. N Engl J Med (2010) 7.52
Exome sequencing identifies GRIN2A as frequently mutated in melanoma. Nat Genet (2011) 7.31
Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma. Nat Genet (2012) 7.00
Whole-genome and whole-exome sequencing of bladder cancer identifies frequent alterations in genes involved in sister chromatid cohesion and segregation. Nat Genet (2013) 3.87
Examination of mutations in BRAF, NRAS, and PTEN in primary cutaneous melanoma. J Invest Dermatol (2006) 2.87
Genetic evidence for lineage-related and differentiation stage-related contribution of somatic PTPN11 mutations to leukemogenesis in childhood acute leukemia. Blood (2004) 2.19
The GDNF/RET signaling pathway and human diseases. Cytokine Growth Factor Rev (2001) 2.05
Desmoplastic malignant melanoma (a rare variant of spindle cell melanoma). Cancer (1971) 2.02
Clinical correlates of NRAS and BRAF mutations in primary human melanoma. Clin Cancer Res (2010) 1.78
Cancer-associated mutations in chromatin remodeler hSNF5 promote chromosomal instability by compromising the mitotic checkpoint. Genes Dev (2005) 1.61
Frequency and spectrum of BRAF mutations in a retrospective, single-institution study of 1112 cases of melanoma. J Mol Diagn (2012) 1.59
The prognostic value of BRAF mutation in colorectal cancer and melanoma: a systematic review and meta-analysis. PLoS One (2012) 1.34
Absence of BRAF mutations in UV-protected mucosal melanomas. J Med Genet (2004) 1.32
Desmoplastic melanoma: a diagnostic trap for the unwary. Pathology (2004) 1.29
Cutaneous desmoplastic melanoma. Adv Anat Pathol (2005) 1.27
Cutaneous melanoma subtypes show different BRAF and NRAS mutation frequencies. Clin Cancer Res (2006) 1.22
Desmoplastic neurotropic melanoma: a clinicopathologic analysis of 128 cases. Cancer (2008) 1.22
The clinical behavior of desmoplastic melanoma. Am J Surg (2001) 1.21
A phase II trial of AS1411 (a novel nucleolin-targeted DNA aptamer) in metastatic renal cell carcinoma. Invest New Drugs (2013) 1.19
Absence of V599E BRAF mutations in desmoplastic melanomas. Cancer (2005) 1.17
BRAF and NRAS mutations are uncommon in melanomas arising in diverse internal organs. J Clin Pathol (2005) 1.17
Absence of BRAF gene mutations in uveal melanomas in contrast to cutaneous melanomas. Br J Cancer (2003) 1.16
Assessment of the role of sentinel lymph node biopsy for primary cutaneous desmoplastic melanoma. Cancer (2006) 1.15
The G691S RET polymorphism increases glial cell line-derived neurotrophic factor-induced pancreatic cancer cell invasion by amplifying mitogen-activated protein kinase signaling. Cancer Res (2005) 1.14
Functional RET G691S polymorphism in cutaneous malignant melanoma. Oncogene (2009) 1.14
Selective RAF inhibitor impairs ERK1/2 phosphorylation and growth in mutant NRAS, vemurafenib-resistant melanoma cells. Pigment Cell Melanoma Res (2013) 1.13
Loss of SNF5 expression correlates with poor patient survival in melanoma. Clin Cancer Res (2009) 1.02
Analysis of GNAQ mutations, proliferation and MAPK pathway activation in uveal melanomas. Br J Ophthalmol (2010) 1.01
BRAF point mutations in primary melanoma show different prevalences by subtype. J Invest Dermatol (2004) 1.00
BRAF and NRAS mutations in spitzoid melanocytic lesions. Mod Pathol (2006) 0.95
Subclassification of desmoplastic melanoma: pure and mixed variants have significantly different capacities for lymph node metastasis. J Cutan Pathol (2009) 0.95
Genetic and clinico-pathologic analysis of metastatic uveal melanoma. Mod Pathol (2013) 0.93
Anatomic site-specific patterns of gene copy number gains in skin, mucosal, and uveal melanomas detected by fluorescence in situ hybridization. Virchows Arch (2006) 0.91
Identification of anaplastic lymphoma kinase break points and oncogenic mutation profiles in acral/mucosal melanomas. Pigment Cell Melanoma Res (2013) 0.90
Mixed versus pure variants of desmoplastic melanoma: a genetic and immunohistochemical appraisal. Mod Pathol (2011) 0.88
Desmoplastic melanoma with sarcomatoid dedifferentiation. Am J Surg Pathol (2014) 0.80
BRAF, NRAS and KIT sequencing analysis of spindle cell melanoma. J Cutan Pathol (2012) 0.78
The RET G691S polymorphism is a germline variant in desmoplastic malignant melanoma. Melanoma Res (2012) 0.78
Desmoplastic malignant melanoma: a study of ten cases and status of BRAF mutation. Dermatology (2012) 0.77
Inferring expressed genes by whole-genome sequencing of plasma DNA. Nat Genet (2016) 1.50
The derived neutrophil/lymphocyte ratio predicts poor clinical outcome in soft tissue sarcoma patients. Am J Surg (2014) 1.46
Changes in colorectal carcinoma genomes under anti-EGFR therapy identified by whole-genome plasma DNA sequencing. PLoS Genet (2014) 1.09
Quality control of RNA preservation and extraction from paraffin-embedded tissue: implications for RT-PCR and microarray analysis. PLoS One (2013) 0.97
Role of adipose tissue in methionine-choline-deficient model of non-alcoholic steatohepatitis (NASH). Biochim Biophys Acta (2014) 0.95
Evaluation of uric acid as a prognostic blood-based marker in a large cohort of pancreatic cancer patients. PLoS One (2014) 0.83
Pre-treatment anemia is a poor prognostic factor in soft tissue sarcoma patients. PLoS One (2014) 0.82
Resolving tumor heterogeneity: genes involved in chordoma cell development identified by low-template analysis of morphologically distinct cells. PLoS One (2014) 0.82
DNA methylation heterogeneity defines a disease spectrum in Ewing sarcoma. Nat Med (2017) 0.81
Visualization of tumor heterogeneity by in situ padlock probe technology in colorectal cancer. Histochem Cell Biol (2017) 0.81
Mutation Profiling of Usual Ductal Hyperplasia of the Breast Reveals Activating Mutations Predominantly at Different Levels of the PI3K/AKT/mTOR Pathway. Am J Pathol (2016) 0.80
Characterisation of Candida within the Mycobiome/Microbiome of the Lower Respiratory Tract of ICU Patients. PLoS One (2016) 0.79
Monoglyceride lipase deficiency modulates endocannabinoid signaling and improves plaque stability in ApoE-knockout mice. Atherosclerosis (2015) 0.78
Somatic TP53 mutations characterize preleukemic stem cells in acute myeloid leukemia. Blood (2017) 0.78
Safety and efficacy of regorafenib in patients with advanced soft tissue sarcoma (REGOSARC): a randomised, double-blind, placebo-controlled, phase 2 trial. Lancet Oncol (2016) 0.77
FOLFOX4 Plus Cetuximab for Patients With Previously Untreated Metastatic Colorectal Cancer According to Tumor RAS and BRAF Mutation Status: Updated Analysis of the CECOG/CORE 1.2.002 Study. Clin Colorectal Cancer (2014) 0.77
Blood-Based Biomarkers Are Associated with Disease Recurrence and Survival in Gastrointestinal Stroma Tumor Patients after Surgical Resection. PLoS One (2016) 0.76
The Prognostic Impact of Unplanned Excisions in a Cohort of 728 Soft Tissue Sarcoma Patients: A Multicentre Study. Ann Surg Oncol (2017) 0.75
Catch and Release: rare cell analysis from a functionalised medical wire. Sci Rep (2017) 0.75
Comparative analysis and modeling of the severity of steatohepatitis in DDC-treated mouse strains. PLoS One (2014) 0.75
Two Case Reports of Rare BRAF Mutations in Exon 11 and Exon 15 with Discussion of Potential Treatment Options. Case Rep Oncol (2016) 0.75
Extended ultrastructural characterization of chordoma cells: the link to new therapeutic options. PLoS One (2014) 0.75
Exploring chromosomal abnormalities and genetic changes in uterine smooth muscle tumors. Mod Pathol (2016) 0.75
Establishment of a novel cellular model for myxofibrosarcoma heterogeneity. Sci Rep (2017) 0.75
Acute myeloid leukemia with TP53 germ line mutations. Blood (2016) 0.75
Loss of adipose triglyceride lipase is associated with human cancer and induces mouse pulmonary neoplasia. Oncotarget (2016) 0.75
Case Report: Epstein-Barr-Virus negative diffuse large B-cell lymphoma detected in a peri-prosthetic membrane. Diagn Pathol (2016) 0.75
MUG-Mel2, a novel highly pigmented and well characterized NRAS mutated human melanoma cell line. Sci Rep (2017) 0.75
The TP53 Pro72Arg SNP in de novo acute myeloid leukaemia - results of two cohort studies involving 215 patients and 3759 controls. Br J Haematol (2017) 0.75
Neuroblastoma causes alterations of the intestinal microbiome, gut hormones, inflammatory cytokines, and bile acid composition. Pediatr Blood Cancer (2017) 0.75
HPV-negative penile squamous cell carcinoma: disruptive mutations in the TP53 gene are common. Mod Pathol (2017) 0.75
In vitro and in vivo cytotoxic activity of human lactoferricin derived antitumor peptide R-DIM-P-LF11-334 on human malignant melanoma. Oncotarget (2017) 0.75
Usual interstitial pneumonia and smoking-related interstitial fibrosis display epithelial to mesenchymal transition in fibroblastic foci. Respir Med (2014) 0.75
APMAP interacts with lysyl oxidase-like proteins, and disruption of Apmap leads to beneficial visceral adipose tissue expansion. FASEB J (2017) 0.75
Expanded molecular profiling of myxofibrosarcoma reveals potentially actionable targets. Mod Pathol (2017) 0.75
A novel mutation in ATRX associated with intellectual disability, syndromic features, and osteosarcoma. Pediatr Blood Cancer (2017) 0.75
Exposure of tropoelastin to peroxynitrous acid gives high yields of nitrated tyrosine residues, di-tyrosine cross-links and altered protein structure and function. Free Radic Biol Med (2017) 0.75
Expansion of BCR/ABL1(+) cells requires PAK2 but not PAK1. Br J Haematol (2017) 0.75
Corrigendum to "Tumor Macroenvironment and Metabolism" [Seminars in Oncology, Vol 41, No 2, April 2014, pp 281-295]. Semin Oncol (2014) 0.75
The Influence of Proton Pump Inhibitors on the Fecal Microbiome of Infants with Gastroesophageal Reflux-A Prospective Longitudinal Interventional Study. Front Cell Infect Microbiol (2017) 0.75
Gut microbiota and body composition in anorexia nervosa inpatients in comparison to athletes, overweight, obese, and normal weight controls. Int J Eat Disord (2017) 0.75
SOX9 is a proliferation and stem cell factor in hepatocellular carcinoma and possess widespread prognostic significance in different cancer types. PLoS One (2017) 0.75
Congenital Infantile Fibrosarcoma Causing Intestinal Perforation in a Newborn. Case Rep Pediatr (2017) 0.75
Surgical Management of Duodenal Gastrointestinal Stromal Tumors: A Case Report. Anticancer Res (2015) 0.75
Tumour heterogeneity: principles and practical consequences. Virchows Arch (2016) 0.75