Published in Cancer Res on October 01, 2001
A hyper-dynamic equilibrium between promoter-bound and nucleoplasmic dimers controls NF-kappaB-dependent gene activity. EMBO J (2006) 2.41
Simulated body temperature rhythms reveal the phase-shifting behavior and plasticity of mammalian circadian oscillators. Genes Dev (2012) 1.48
Amplification of a plasmid bearing a mammalian replication initiation region in chromosomal and extrachromosomal contexts. Nucleic Acids Res (2010) 1.16
Restriction to Fos family members of Trip6-dependent coactivation and glucocorticoid receptor-dependent trans-repression of activator protein-1. Mol Endocrinol (2008) 1.06
Tracking of microinjected DNA in live cells reveals the intracellular behavior and elimination of extrachromosomal genetic material. Nucleic Acids Res (2005) 0.92
Efficient recombinant production in mammalian cells using a novel IR/MAR gene amplification method. PLoS One (2012) 0.91
How transcription proceeds in a large artificial heterochromatin in human cells. Nucleic Acids Res (2008) 0.88
Fusion of the Dhfr/Mtx and IR/MAR gene amplification methods produces a rapid and efficient method for stable recombinant protein production. PLoS One (2012) 0.86
Episomal high copy number maintenance of hairpin-capped DNA bearing a replication initiation region in human cells. J Biol Chem (2009) 0.85
Generation of micronuclei during interphase by coupling between cytoplasmic membrane blebbing and nuclear budding. PLoS One (2011) 0.85
Characterization at nucleotide resolution of the homogeneously staining region sites of insertion in two cancer cell lines. Nucleic Acids Res (2013) 0.84
Dissection of the beta-globin replication-initiation region reveals specific requirements for replicator elements during gene amplification. PLoS One (2013) 0.83
How a replication origin and matrix attachment region accelerate gene amplification under replication stress in mammalian cells. PLoS One (2014) 0.79
Cloning and Characterization of a Human Genomic Sequence that Alleviates Repeat-Induced Gene Silencing. PLoS One (2016) 0.79
The LIM domain protein nTRIP6 recruits the mediator complex to AP-1-regulated promoters. PLoS One (2014) 0.78
Regulatory Elements in Vectors for Efficient Generation of Cell Lines Producing Target Proteins. Acta Naturae (2015) 0.77
Amplicon rearrangements during the extrachromosomal and intrachromosomal amplification process in a glioma. Nucleic Acids Res (2014) 0.76
Amplification of a transgene within a long array of replication origins favors higher gene expression in animal cells. PLoS One (2017) 0.75
BAC-based cellular model for screening regulators of BDNF gene transcription. BMC Neurosci (2014) 0.75
Epigenetic Repeat-Induced Gene Silencing in the Chromosomal and Extrachromosomal Contexts in Human Cells. PLoS One (2016) 0.75
Application of the novel and convenient IR/MAR gene amplification technology to the production of recombinant protein pharmaceuticals. BMC Proc (2011) 0.75
Healthy percentage body fat ranges: an approach for developing guidelines based on body mass index. Am J Clin Nutr (2000) 5.29
Highly purified murine interleukin 5 (IL-5) stimulates eosinophil function and prolongs in vitro survival. IL-5 as an eosinophil chemotactic factor. J Exp Med (1988) 3.50
In vivo and in vitro stem cell function of c-kit- and Sca-1-positive murine hematopoietic cells. Blood (1992) 3.15
Purified interleukin 5 supports the terminal differentiation and proliferation of murine eosinophilic precursors. J Exp Med (1988) 2.71
No-mortality liver resection for hepatocellular carcinoma in cirrhotic and noncirrhotic patients: is there a way? A prospective analysis of our approach. Arch Surg (1999) 2.47
The slow wave in the circular muscle of the guinea-pig stomach. J Physiol (1975) 2.29
Identification of the amino acid residues involved in an active site of Escherichia coli ribonuclease H by site-directed mutagenesis. J Biol Chem (1990) 2.12
Enrichment and characterization of murine hematopoietic stem cells that express c-kit molecule. Blood (1991) 2.02
Loss-of-function mutations in the rice homeobox gene OSH15 affect the architecture of internodes resulting in dwarf plants. EMBO J (1999) 1.98
Electrical characteristics of pancreatic islet cells. J Physiol (1975) 1.96
Self-organization of supramolecular helical dendrimers into complex electronic materials. Nature (2002) 1.95
Effects of tetraethylammonium chloride on the membrane activity of guinea-pig stomach smooth muscle. J Physiol (1970) 1.95
Positive and negative regulation of myogenic differentiation of C2C12 cells by isoforms of the multiple homeodomain zinc finger transcription factor ATBF1. J Biol Chem (2001) 1.95
Arylamine N-acetyltransferase from chicken liver II. Cloning of cDNA and expression in Chinese hamster ovary cells. J Biol Chem (1988) 1.94
Post-translational modifications of the C-terminal region of the rho protein are important for its interaction with membranes and the stimulatory and inhibitory GDP/GTP exchange proteins. Oncogene (1991) 1.93
Purification of insulin receptor with full binding activity. J Biol Chem (1983) 1.82
Antigenic relationships between rotaviruses from different species as studied by neutralization and immunofluorescence. Arch Virol (1982) 1.72
Effect of growth temperature on lipid and fatty acid compositions in the blue-green algae, Anabaena variabilis and Anacystis nidulans. Biochim Biophys Acta (1979) 1.71
Effector and regulatory cells in autoimmune oophoritis elicited by neonatal thymectomy. J Immunol (1991) 1.69
Vitamin D receptor alleles, bone mineral density and turnover in premenopausal Japanese women. J Bone Miner Res (1996) 1.67
Microinjection of smg/rap1/Krev-1 p21 into Swiss 3T3 cells induces DNA synthesis and morphological changes. Mol Cell Biol (1992) 1.66
cDNA and deduced amino acid sequence of a mouse DNA repair enzyme (APEX nuclease) with significant homology to Escherichia coli exonuclease III. J Biol Chem (1991) 1.64
Pancreatic islet cells: effects of monosaccharides, glycolytic intermediates and metabolic inhibitors on membrane potential and electrical activity. J Physiol (1975) 1.64
Mouse MD-1, a molecule that is physically associated with RP105 and positively regulates its expression. J Immunol (1998) 1.59
The oxidative burst protects plants against pathogen attack: mechanism and role as an emergency signal for plant bio-defence--a review. Gene (1996) 1.59
Generation of osteoclasts from isolated hematopoietic progenitor cells. Blood (1989) 1.55
cDNA cloning, sequencing, expression and possible domain structure of human APEX nuclease homologous to Escherichia coli exonuclease III. Biochim Biophys Acta (1992) 1.55
Bovine leukemia virus matrix-associated protein MA(p15): further processing and formation of a specific complex with the dimer of the 5'-terminal genomic RNA fragment. J Virol (1991) 1.52
Structure, chromosome location, and expression of the human very low density lipoprotein receptor gene. J Biol Chem (1994) 1.51
Analysis of the survival of mature human eosinophils: interleukin-5 prevents apoptosis in mature human eosinophils. Blood (1991) 1.51
A stimulatory effect of recombinant murine interleukin-7 (IL-7) on B-cell colony formation and an inhibitory effect of IL-1 alpha. Blood (1989) 1.48
Gene amplification as a cause of inherited thyroxine-binding globulin excess in two Japanese families. J Clin Endocrinol Metab (1995) 1.47
Sialyl-Tn- and neuron-specific enolase-positive minimally differentiated erythroleukemia. Intern Med (2000) 1.46
The CD40 ligand expressed by human B cells costimulates B cell responses. J Immunol (1995) 1.46
Microtubule network facilitates nuclear targeting of human cytomegalovirus capsid. J Virol (2003) 1.43
Exercise-induced systolic dysfunction in patients with non-obstructive hypertrophic cardiomyopathy and mutations in the cardiac troponin genes. Heart (2008) 1.43
Deletion polymorphism of the angiotensin I-converting enzyme gene is associated with serum ACE concentration and increased risk for CAD in the Japanese. Circulation (1994) 1.43
Biologic significance of angiopoietin-2 expression in human hepatocellular carcinoma. J Clin Invest (1999) 1.42
Chronic cervical cord compression: clinical significance of increased signal intensity on MR images. Radiology (1989) 1.41
Synbindin, A novel syndecan-2-binding protein in neuronal dendritic spines. J Cell Biol (2000) 1.41
Structurally abnormal insulin in a diabetic patient. Characterization of the mutant insulin A3 (Val----Leu) isolated from the pancreas. J Clin Invest (1986) 1.39
Therapeutic effect of clarithromycin for respiratory-tract infections in children caused by Chlamydia pneumoniae. Research Group of Sapporo for Pediatric Chlamydial Infections. Int J Antimicrob Agents (2000) 1.39
Euthanasia, physician-assisted suicide, and persistent vegetative state. Lancet (1996) 1.39
High fever, renal failure, disseminated intravascular coagulation and myelodysplasia accompanied with enhanced angiogenesis possibly due to overexpression of vascular endothelial growth factor. Intern Med (2000) 1.38
Multiple endocrine neoplasia type 2A with the identical somatic mutation in medullary thyroid carcinoma and pheochromocytoma without germline mutation at the corresponding site in the RET proto-oncogene. Intern Med (1999) 1.38
Single-strand DNA cleavages by eukaryotic topoisomerase II. Biochemistry (1988) 1.38
Acute promyelocytic leukaemia, tretinoin, and granulocyte colony-stimulating factor. Lancet (1994) 1.38
Hypertrophic olivary degeneration: MR imaging and pathologic findings. Radiology (1994) 1.36
Congenital insensitivity to pain with anhidrosis: novel mutations in the TRKA (NTRK1) gene encoding a high-affinity receptor for nerve growth factor. Am J Hum Genet (1999) 1.36
Effects of CPT-11 in combination with other anti-cancer agents in culture. Int J Cancer (1992) 1.36
Induction of blood-brain barrier properties in immortalized bovine brain endothelial cells by astrocytic factors. Neurosci Res (1999) 1.34
Shellfish and fish poisoning related to the toxic dinoflagellates. South Med J (1987) 1.34
Isolation of bovine arboviruses from Culicoides biting midges (Diptera: Ceratopogonidae) in southern Japan: 1985--2002. J Med Entomol (2005) 1.34
Serologic evidence for etiologic role of Akabane virus in epizootic abortion-arthrogryposis-hydranencephaly in cattle in Japan, 1972-1974. Arch Virol (1975) 1.34
Involvement of DNA topoisomerase IIbeta in neuronal differentiation. J Biol Chem (2000) 1.34
Cystic hygroma of the chest wall: a rare condition. Ann Plast Surg (1996) 1.33
Effects of sodium, potassium and calcium ions on the slow wave in the circular muscle of the guinea-pig stomach. J Physiol (1977) 1.33
Serum thioredoxin levels as an indicator of oxidative stress in patients with hepatitis C virus infection. J Hepatol (2000) 1.32
Resveratrol suppresses hepatoma cell invasion independently of its anti-proliferative action. Cancer Lett (2001) 1.30
Affinity chromatography of heme-binding proteins: an improved method for the synthesis of hemin-agarose. Anal Biochem (1982) 1.29
A new technique for the cytochemical examination of human hemopoietic cells grown in agar gel. Exp Hematol (1980) 1.29
Increased MR signal intensity secondary to chronic cervical cord compression. Neuroradiology (1987) 1.29
The expression of ST2 gene in helper T cells and the binding of ST2 protein to myeloma-derived RPMI8226 cells. J Biochem (1997) 1.29
Induction of apoptosis and cell cycle arrest in cancer cells by in vivo metabolites of teas. Nutr Cancer (2000) 1.28
Effects of green, oolong and black teas and related components on the proliferation and invasion of hepatoma cells in culture. Cytotechnology (1999) 1.28
Characterization of a cDNA encoding a novel avian hypothalamic neuropeptide exerting an inhibitory effect on gonadotropin release. Biochem J (2001) 1.27
Pancreatic islet cells: electrogenic and electrodiffusional control of membrane potential. J Physiol (1975) 1.26
Increased carotenoid production by the food yeast Candida utilis through metabolic engineering of the isoprenoid pathway. Appl Environ Microbiol (1998) 1.26
Expression of a betaine aldehyde dehydrogenase gene in rice, a glycinebetaine nonaccumulator, and possible localization of its protein in peroxisomes. Plant J (1997) 1.25
Metabolism and functional effects of sphingolipids in blood cells. Br J Haematol (1999) 1.24
Advance directives and withdrawal of dialysis in the United States, Germany, and Japan. JAMA (1996) 1.24
Gonadotropin-inhibitory peptide in song sparrows (Melospiza melodia) in different reproductive conditions, and in house sparrows (Passer domesticus) relative to chicken-gonadotropin-releasing hormone. J Neuroendocrinol (2003) 1.23
SOCS-1/JAB/SSI-1 can bind to and suppress Tec protein-tyrosine kinase. J Biol Chem (1997) 1.23
In vitro characterization of astaxanthin biosynthetic enzymes. J Biol Chem (1997) 1.23
Assimilation of liquid hydrocarbon by microorganisms. I. Mechanism of hydrocarbon uptake. Biotechnol Bioeng (1977) 1.22
Inhibitory effects of carotenoids on the invasion of rat ascites hepatoma cells in culture. Cancer Lett (2000) 1.22
Studies on the regulation of glutathione level in rat liver. J Biochem (1974) 1.20
A recombinant murine granulocyte/macrophage (GM) colony-stimulating factor derived from an inducer T cell line (IH5.5). Functional restriction to GM progenitor cells. J Exp Med (1986) 1.20
An extra idic(15p)(q11) chromosome in Prader-Willi syndrome. Hum Genet (1980) 1.19
Electron and immunoelectron microscopic study of Dane particle formation in chronic hepatitis B virus infection. Gastroenterology (1982) 1.19
Validation of a simple histological-histochemical cartilage scoring system. Tissue Eng (2001) 1.18
Evidence for a role of p38 MAP kinase in expression of alkaline phosphatase during osteoblastic cell differentiation. Bone (2002) 1.18
Membrane characteristics of the canine papillary muscle fiber. J Gen Physiol (1969) 1.18
HYS2, an essential gene required for DNA replication in Saccharomyces cerevisiae. Nucleic Acids Res (1995) 1.18
Immunological studies on aphthous ulcer and erythema nodosum-like eruptions in Behcet's disease. Br J Dermatol (1985) 1.18
Some electrical properties of the slow potential changes recorded from the guinea pig stomach in relation to drug actions. Jpn J Physiol (1972) 1.17
Genetically determined aberrant down-regulation of FcgammaRIIB1 in germinal center B cells associated with hyper-IgG and IgG autoantibodies in murine systemic lupus erythematosus. Int Immunol (1999) 1.17
Gonadotropin-inhibitory hormone in Gambel's white-crowned sparrow (Zonotrichia leucophrys gambelii): cDNA identification, transcript localization and functional effects in laboratory and field experiments. J Endocrinol (2004) 1.17
Properties of polyriboadenylic acid from rat liver. Arch Biochem Biophys (1970) 1.17
Neural coding of 3D features of objects for hand action in the parietal cortex of the monkey. Philos Trans R Soc Lond B Biol Sci (1998) 1.16
Recombinant human granulocyte colony-stimulating factor enhances superoxide release in human granulocytes stimulated by the chemotactic peptide. Biochem Biophys Res Commun (1987) 1.16
Induction of tyrosine phosphorylation of Vav and expression of Pim-1 correlates with Jak2-mediated growth signaling from the erythropoietin receptor. Blood (1994) 1.16
Selective suppression of nucleolar RNA metabolism in the absence of protein synthesis. Biochim Biophys Acta (1968) 1.15
Chemosensitization by buthionine sulfoximine in vivo. Int J Radiat Oncol Biol Phys (1986) 1.15
A dual signaling cascade that regulates the ectodomain shedding of heparin-binding epidermal growth factor-like growth factor. J Biol Chem (2001) 1.15
Intravenous injection of rabbit apolipoprotein A-I inhibits the progression of atherosclerosis in cholesterol-fed rabbits. Arterioscler Thromb Vasc Biol (1995) 1.15
Medical decisions concerning the end of life: a discussion with Japanese physicians. J Med Ethics (1997) 1.15