Published in BMC Biotechnol on September 26, 2001
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Cre-lox-based system for multiple gene deletions and selectable-marker removal in Lactobacillus plantarum. Appl Environ Microbiol (2006) 1.70
An experimental system for the evaluation of retroviral vector design to diminish the risk for proto-oncogene activation. Blood (2007) 1.57
Activation-induced cytidine deaminase initiates immunoglobulin gene conversion and hypermutation by a common intermediate. PLoS Biol (2004) 1.56
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FANCJ coordinates two pathways that maintain epigenetic stability at G-quadruplex DNA. Nucleic Acids Res (2011) 1.45
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Loss of centrioles causes chromosomal instability in vertebrate somatic cells. J Cell Biol (2013) 1.28
A cis-acting diversification activator both necessary and sufficient for AID-mediated hypermutation. PLoS Genet (2009) 1.24
Phosphorylation switches the general splicing repressor SRp38 to a sequence-specific activator. Nat Struct Mol Biol (2008) 1.22
Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis. Genome Biol (2004) 1.22
Tumor suppressor and deubiquitinase BAP1 promotes DNA double-strand break repair. Proc Natl Acad Sci U S A (2013) 1.21
Role for RAD18 in homologous recombination in DT40 cells. Mol Cell Biol (2006) 1.19
The receptor for the subgroup C avian sarcoma and leukosis viruses, Tvc, is related to mammalian butyrophilins, members of the immunoglobulin superfamily. J Virol (2005) 1.17
TopBP1/Dpb11 binds DNA anaphase bridges to prevent genome instability. J Cell Biol (2013) 1.16
Regulation of the DNA damage response and gene expression by the Dot1L histone methyltransferase and the 53Bp1 tumour suppressor. PLoS One (2011) 1.16
Interplay between DNA polymerases beta and lambda in repair of oxidation DNA damage in chicken DT40 cells. DNA Repair (Amst) (2007) 1.14
Control of gene conversion and somatic hypermutation by immunoglobulin promoter and enhancer sequences. J Exp Med (2006) 1.14
Protein evolution by hypermutation and selection in the B cell line DT40. Nucleic Acids Res (2007) 1.05
Determinants of G quadruplex-induced epigenetic instability in REV1-deficient cells. EMBO J (2014) 1.04
Functional redundancy between DNA ligases I and III in DNA replication in vertebrate cells. Nucleic Acids Res (2011) 1.03
DNA ligases I and III cooperate in alternative non-homologous end-joining in vertebrates. PLoS One (2013) 1.02
Knock-in/Knock-out (KIKO) vectors for rapid integration of large DNA sequences, including whole metabolic pathways, onto the Escherichia coli chromosome at well-characterised loci. Microb Cell Fact (2013) 0.98
Defective nucleotide excision repair with normal centrosome structures and functions in the absence of all vertebrate centrins. J Cell Biol (2011) 0.98
Targeting of somatic hypermutation by immunoglobulin enhancer and enhancer-like sequences. PLoS Biol (2014) 0.95
A CEP215-HSET complex links centrosomes with spindle poles and drives centrosome clustering in cancer. Nat Commun (2016) 0.95
Heat shock factor 2 is required for maintaining proteostasis against febrile-range thermal stress and polyglutamine aggregation. Mol Biol Cell (2011) 0.95
Involvement of Rad18 in somatic hypermutation. Proc Natl Acad Sci U S A (2006) 0.94
A novel MCF-10A line allowing conditional oncogene expression in 3D culture. Cell Commun Signal (2011) 0.94
Multiple myeloma-associated hDIS3 mutations cause perturbations in cellular RNA metabolism and suggest hDIS3 PIN domain as a potential drug target. Nucleic Acids Res (2013) 0.93
The RNA editing enzyme APOBEC1 induces somatic mutations and a compatible mutational signature is present in esophageal adenocarcinomas. Genome Biol (2014) 0.91
Separation of mutational and transcriptional enhancers in Ig genes. J Immunol (2011) 0.90
Genetic manipulation of an exogenous non-immunoglobulin protein by gene conversion machinery in a chicken B cell line. Nucleic Acids Res (2006) 0.90
USF binding sequences from the HS4 insulator element impose early replication timing on a vertebrate replicator. PLoS Biol (2012) 0.89
TopBP1 is required at mitosis to reduce transmission of DNA damage to G1 daughter cells. J Cell Biol (2015) 0.88
Brca1 in immunoglobulin gene conversion and somatic hypermutation. DNA Repair (Amst) (2007) 0.88
Engineering biological systems using automated biofoundries. Metab Eng (2017) 0.85
Variations in intracellular levels of TATA binding protein can affect specific genes by different mechanisms. Mol Cell Biol (2007) 0.85
Engineering an efficient and tight D-amino acid-inducible gene expression system in Rhodosporidium/Rhodotorula species. Microb Cell Fact (2015) 0.83
Evaluation of the chicken transcriptome by SAGE of B cells and the DT40 cell line. BMC Genomics (2004) 0.83
Phosphorylation at carboxyl-terminal S373 and S375 residues and 14-3-3 binding are not required for mouse p53 function. Neoplasia (2007) 0.82
Construction of monophosphoryl lipid A producing Escherichia coli mutants and comparison of immuno-stimulatory activities of their lipopolysaccharides. Mar Drugs (2013) 0.82
The Werner's Syndrome protein collaborates with REV1 to promote replication fork progression on damaged DNA. DNA Repair (Amst) (2010) 0.82
Interaction between DNA Polymerase β and BRCA1. PLoS One (2013) 0.82
Checkpoint kinase 1 negatively regulates somatic hypermutation. Nucleic Acids Res (2014) 0.81
Classical Mus musculus Igκ enhancers support transcription but not high level somatic hypermutation from a V-lambda promoter in chicken DT40 cells. PLoS One (2011) 0.81
A new strategy for gene targeting and functional proteomics using the DT40 cell line. Nucleic Acids Res (2013) 0.79
Application of the bacteriophage Mu-driven system for the integration/amplification of target genes in the chromosomes of engineered Gram-negative bacteria--mini review. Appl Microbiol Biotechnol (2011) 0.79
Telomere length homeostasis and telomere position effect on a linear human artificial chromosome are dictated by the genetic background. Nucleic Acids Res (2012) 0.78
Visualisation of PCNA monoubiquitination in vivo by single pass spectral imaging FRET microscopy. PLoS One (2010) 0.78
Activation of the chicken Ig-beta locus by the collaboration of scattered regulatory regions through changes in chromatin structure. Nucleic Acids Res (2006) 0.77
MSH6- or PMS2-deficiency causes re-replication in DT40 B cells, but it has little effect on immunoglobulin gene conversion or on repair of AID-generated uracils. Nucleic Acids Res (2013) 0.76
Centriole splitting caused by loss of the centrosomal linker protein C-NAP1 reduces centriolar satellite density and impedes centrosome amplification. Mol Biol Cell (2017) 0.76
Rac-mediated Stimulation of Phospholipase Cγ2 Amplifies B Cell Receptor-induced Calcium Signaling. J Biol Chem (2015) 0.76
Restoration of mismatch repair functions in human cell line Nalm-6, which has high efficiency for gene targeting. PLoS One (2013) 0.76
Alternative Okazaki Fragment Ligation Pathway by DNA Ligase III. Genes (Basel) (2015) 0.76
A method to convert mRNA into a gRNA library for CRISPR/Cas9 editing of any organism. Sci Adv (2016) 0.76
A double-strand break can trigger immunoglobulin gene conversion. Nucleic Acids Res (2016) 0.75
Checkpoint kinase 2 is required for efficient immunoglobulin diversification. Cell Cycle (2014) 0.75
Ubc13 dosage is critical for immunoglobulin gene conversion and gene targeting in vertebrate cells. Nucleic Acids Res (2010) 0.75
Efficient transgene expression system using a cumate-inducible promoter and Cre-loxP recombination in avian cells. Asian-Australas J Anim Sci (2016) 0.75
Involvement of the specific nucleolar protein SURF6 in regulation of proliferation and ribosome biogenesis in mouse NIH/3T3 fibroblasts. Cell Cycle (2017) 0.75
An efficient method to enrich for knock-out and knock-in cellular clones using the CRISPR/Cas9 system. Cell Mol Life Sci (2017) 0.75
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Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme. Cell (2000) 20.83
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Reduced X-ray resistance and homologous recombination frequencies in a RAD54-/- mutant of the chicken DT40 cell line. Cell (1997) 3.23
Targeted integration of DNA using mutant lox sites in embryonic stem cells. Nucleic Acids Res (1997) 2.27
Comparison of the tamoxifen regulated chimeric Cre recombinases MerCreMer and CreMer. Biol Chem (1999) 1.47
Cell cycle arrest and apoptosis induced by Notch1 in B cells. J Biol Chem (2000) 1.45
The chicken HPRT gene: a counter selectable marker for the DT40 cell line. Nucleic Acids Res (1999) 1.27
The chicken B cell line DT40: a novel tool for gene disruption experiments. J Immunol Methods (2001) 1.25
Rad51-deficient vertebrate cells accumulate chromosomal breaks prior to cell death. EMBO J (1998) 6.65
A mouse cytoplasmic exoribonuclease (mXRN1p) with preference for G4 tetraplex substrates. J Cell Biol (1997) 4.93
Reduced X-ray resistance and homologous recombination frequencies in a RAD54-/- mutant of the chicken DT40 cell line. Cell (1997) 3.23
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Characterization of the roles of the Saccharomyces cerevisiae RAD54 gene and a homologue of RAD54, RDH54/TID1, in mitosis and meiosis. Genetics (1997) 2.31
Homologous recombination, but not DNA repair, is reduced in vertebrate cells deficient in RAD52. Mol Cell Biol (1998) 2.19
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The Drosophila melanogaster RAD54 homolog, DmRAD54, is involved in the repair of radiation damage and recombination. Mol Cell Biol (1997) 1.29
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A large database of chicken bursal ESTs as a resource for the analysis of vertebrate gene function. Genome Res (2000) 1.24
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Complex genetic predisposition to cancer in an extended HNPCC family with an ancestral hMLH1 mutation. J Med Genet (1996) 0.99
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