Published in Nucleic Acids Res on January 13, 2014
MicroRNA 155 control of p53 activity is context dependent and mediated by Aicda and Socs1. Mol Cell Biol (2015) 0.80
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Checkpoint kinase 2 is required for efficient immunoglobulin diversification. Cell Cycle (2014) 0.75
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Regulation of DNA repair throughout the cell cycle. Nat Rev Mol Cell Biol (2008) 5.10
The BCL6 proto-oncogene suppresses p53 expression in germinal-centre B cells. Nature (2004) 5.06
Altering the pathway of immunoglobulin hypermutation by inhibiting uracil-DNA glycosylase. Nature (2002) 4.89
Activation-induced cytidine deaminase deaminates deoxycytidine on single-stranded DNA but requires the action of RNase. Proc Natl Acad Sci U S A (2003) 4.89
The cell-cycle checkpoint kinase Chk1 is required for mammalian homologous recombination repair. Nat Cell Biol (2005) 4.62
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A hyperconversion mechanism generates the chicken light chain preimmune repertoire. Cell (1987) 4.23
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Ablation of XRCC2/3 transforms immunoglobulin V gene conversion into somatic hypermutation. Nature (2001) 3.09
Requirement of the activation-induced deaminase (AID) gene for immunoglobulin gene conversion. Science (2002) 3.04
Chk1 is haploinsufficient for multiple functions critical to tumor suppression. Cancer Cell (2004) 2.94
Activation-induced cytidine deaminase targets DNA at sites of RNA polymerase II stalling by interaction with Spt5. Cell (2010) 2.92
Bcl-6 mediates the germinal center B cell phenotype and lymphomagenesis through transcriptional repression of the DNA-damage sensor ATR. Nat Immunol (2007) 2.90
Chk1-deficient tumour cells are viable but exhibit multiple checkpoint and survival defects. EMBO J (2003) 2.76
TdT-accessible breaks are scattered over the immunoglobulin V domain in a constitutively hypermutating B cell line. Immunity (1998) 2.76
A role for activation-induced cytidine deaminase in the host response against a transforming retrovirus. Immunity (2006) 2.27
Mutant loxP vectors for selectable marker recycle and conditional knock-outs. BMC Biotechnol (2001) 2.09
Taking the time to make important decisions: the checkpoint effector kinases Chk1 and Chk2 and the DNA damage response. DNA Repair (Amst) (2009) 1.89
Fanconi anemia FANCG protein in mitigating radiation- and enzyme-induced DNA double-strand breaks by homologous recombination in vertebrate cells. Mol Cell Biol (2003) 1.84
Widespread genomic breaks generated by activation-induced cytidine deaminase are prevented by homologous recombination. Nat Immunol (2010) 1.62
A/T mutagenesis in hypermutated immunoglobulin genes strongly depends on PCNAK164 modification. J Exp Med (2007) 1.57
Activation-induced cytidine deaminase initiates immunoglobulin gene conversion and hypermutation by a common intermediate. PLoS Biol (2004) 1.56
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Disruption of ATM in p53-null cells causes multiple functional abnormalities in cellular response to ionizing radiation. Oncogene (1999) 1.35
Structural basis for Chk1 inhibition by UCN-01. J Biol Chem (2002) 1.34
The checkpoint kinases Chk1 and Chk2 regulate the functional associations between hBRCA2 and Rad51 in response to DNA damage. Oncogene (2008) 1.24
Dealing with DNA damage: relationships between checkpoint and repair pathways. Mutat Res (2009) 1.22
BCL6 represses CHEK1 and suppresses DNA damage pathways in normal and malignant B-cells. Blood Cells Mol Dis (2008) 1.21
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Breaking down cell cycle checkpoints and DNA repair during antigen receptor gene assembly. Oncogene (2007) 1.11
Analysis of gene expression, copy number and palindrome formation with a Dt40 enriched cDNA microarray. Subcell Biochem (2006) 0.86
Structure-based design and synthesis of (5-arylamino-2H-pyrazol-3-yl)-biphenyl-2',4'-diols as novel and potent human CHK1 inhibitors. J Med Chem (2007) 0.85
c-Myc overexpression promotes a germinal center-like program in Burkitt's lymphoma. Oncogene (2009) 0.84
Episomal vectors to monitor and induce somatic hypermutation in human Burkitt-Lymphoma cell lines. Mol Immunol (2005) 0.82
Selective induction of DNA repair pathways in human B cells activated by CD4+ T cells. PLoS One (2010) 0.79
The absence of a functional relationship between ATM and BLM, the components of BASC, in DT40 cells. Biochim Biophys Acta (2004) 0.77
Loss of intestinal crypt progenitor cells owing to inactivation of both Notch1 and Notch2 is accompanied by derepression of CDK inhibitors p27Kip1 and p57Kip2. EMBO Rep (2008) 3.03
Canonical Notch2 signaling determines biliary cell fates of embryonic hepatoblasts and adult hepatocytes independent of Hes1. Hepatology (2013) 2.34
Liver-specific inactivation of Notch2, but not Notch1, compromises intrahepatic bile duct development in mice. Hepatology (2008) 2.21
Loss of the B-lineage-specific gene expression program in Hodgkin and Reed-Sternberg cells of Hodgkin lymphoma. Blood (2002) 1.91
Notch2 is required for progression of pancreatic intraepithelial neoplasia and development of pancreatic ductal adenocarcinoma. Proc Natl Acad Sci U S A (2010) 1.84
Hierarchy of Notch-Delta interactions promoting T cell lineage commitment and maturation. J Exp Med (2007) 1.73
Control of Epstein-Barr virus reactivation by activated CD40 and viral latent membrane protein 1. Proc Natl Acad Sci U S A (2001) 1.40
Notch1 and Notch2 receptors influence progressive hair graying in a dose-dependent manner. Dev Dyn (2007) 1.40
Constitutive CD40 signaling in B cells selectively activates the noncanonical NF-kappaB pathway and promotes lymphomagenesis. J Exp Med (2008) 1.34
Rescue of "crippled" germinal center B cells from apoptosis by Epstein-Barr virus. Blood (2005) 1.18
The fusion kinase ITK-SYK mimics a T cell receptor signal and drives oncogenesis in conditional mouse models of peripheral T cell lymphoma. J Exp Med (2010) 1.18
Conditional ablation of Notch signaling in pancreatic development. Development (2008) 1.16
Epstein-Barr virus nuclear antigen 2 inhibits AID expression during EBV-driven B-cell growth. Blood (2006) 1.11
LMP1 signaling can replace CD40 signaling in B cells in vivo and has unique features of inducing class-switch recombination to IgG1. Blood (2007) 1.05
CD19-independent instruction of murine marginal zone B-cell development by constitutive Notch2 signaling. Blood (2011) 1.00
Differential expression of activation-induced cytidine deaminase (AID) in nodular lymphocyte-predominant and classical Hodgkin lymphoma. J Pathol (2005) 0.98
Human splenic marginal zone B cells lack expression of activation-induced cytidine deaminase. Eur J Immunol (2005) 0.98
Identification of epidermal Pdx1 expression discloses different roles of Notch1 and Notch2 in murine Kras(G12D)-induced skin carcinogenesis in vivo. PLoS One (2010) 0.97
Involvement of Rad18 in somatic hypermutation. Proc Natl Acad Sci U S A (2006) 0.94
Programming of marginal zone B-cell fate by basic Kruppel-like factor (BKLF/KLF3). Blood (2011) 0.84
Asymmetric Arginine dimethylation of Epstein-Barr virus nuclear antigen 2 promotes DNA targeting. Virology (2009) 0.84
Absence of immunoglobulin class switch in primary lymphomas of the central nervous system. Am J Pathol (2005) 0.81
Immune modulation by Fas ligand reverse signaling: lymphocyte proliferation is attenuated by the intracellular Fas ligand domain. Blood (2010) 0.78
Non-conservative homologous recombination in human B lymphocytes is promoted by activation-induced cytidine deaminase and transcription. Nucleic Acids Res (2008) 0.78
Restricted expression of Epstein-Barr virus latent genes in murine B cells derived from embryonic stem cells. PLoS One (2008) 0.77
Expression of activation-induced cytidine deaminase in malignant lymphomas infiltrating the bone marrow. Appl Immunohistochem Mol Morphol (2008) 0.77
The expression of activation induced cytidine deaminase in follicular lymphoma is independent of prognosis and stage. Histopathology (2009) 0.77
B- and T-cell-specific inactivation of thioredoxin reductase 2 does not impair lymphocyte development and maintenance. Biol Chem (2007) 0.76
Humanized c-Myc mouse. PLoS One (2012) 0.76
Erratum: CD40-signalling abrogates induction of RORγt(+) Treg cells by intestinal CD103(+) DCs and causes fatal colitis. Nat Commun (2017) 0.75
An RNAi-based approach to down-regulate a gene family in vivo. PLoS One (2013) 0.75
Checkpoint kinase 2 is required for efficient immunoglobulin diversification. Cell Cycle (2014) 0.75
Ubc13 dosage is critical for immunoglobulin gene conversion and gene targeting in vertebrate cells. Nucleic Acids Res (2010) 0.75
Corrigendum: Regulation of monocyte cell fate by blood vessels mediated by Notch signalling. Nat Commun (2017) 0.75