1
|
Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex.
|
Nature
|
1998
|
18.36
|
2
|
MBD2 is a transcriptional repressor belonging to the MeCP1 histone deacetylase complex.
|
Nat Genet
|
1999
|
5.61
|
3
|
HDA1 and RPD3 are members of distinct yeast histone deacetylase complexes that regulate silencing and transcription.
|
Proc Natl Acad Sci U S A
|
1996
|
5.61
|
4
|
The inactive X chromosome in female mammals is distinguished by a lack of histone H4 acetylation, a cytogenetic marker for gene expression.
|
Cell
|
1993
|
4.76
|
5
|
Transcriptional repression by UME6 involves deacetylation of lysine 5 of histone H4 by RPD3.
|
Nature
|
1998
|
4.43
|
6
|
Efficient transcriptional silencing in Saccharomyces cerevisiae requires a heterochromatin histone acetylation pattern.
|
Mol Cell Biol
|
1996
|
3.72
|
7
|
Transient inhibition of histone deacetylation alters the structural and functional imprint at fission yeast centromeres.
|
Cell
|
1997
|
3.72
|
8
|
Essential and redundant functions of histone acetylation revealed by mutation of target lysines and loss of the Gcn5p acetyltransferase.
|
EMBO J
|
1998
|
3.52
|
9
|
Acetylated histone H4 on the male X chromosome is associated with dosage compensation in Drosophila.
|
Genes Dev
|
1994
|
3.31
|
10
|
General transcription factors bind promoters repressed by Polycomb group proteins.
|
Nature
|
2001
|
3.23
|
11
|
Expanded lysine acetylation specificity of Gcn5 in native complexes.
|
J Biol Chem
|
1999
|
2.91
|
12
|
Histone H4 acetylation distinguishes coding regions of the human genome from heterochromatin in a differentiation-dependent but transcription-independent manner.
|
EMBO J
|
1995
|
2.86
|
13
|
X-Inactivation and histone H4 acetylation in embryonic stem cells.
|
Dev Biol
|
1996
|
2.50
|
14
|
Nuclear organization of mammalian genomes. Polar chromosome territories build up functionally distinct higher order compartments.
|
J Cell Biol
|
1999
|
2.19
|
15
|
Histone deacetylases in acute myeloid leukaemia show a distinctive pattern of expression that changes selectively in response to deacetylase inhibitors.
|
Leukemia
|
2005
|
2.15
|
16
|
Duplication and maintenance of heterochromatin domains.
|
J Cell Biol
|
1999
|
2.12
|
17
|
Xist RNA exhibits a banded localization on the inactive X chromosome and is excluded from autosomal material in cis.
|
Hum Mol Genet
|
1999
|
1.90
|
18
|
Histone H4 acetylation of euchromatin and heterochromatin is cell cycle dependent and correlated with replication rather than with transcription.
|
Plant Cell
|
2000
|
1.75
|
19
|
Identification of a conserved erythroid specific domain of histone acetylation across the alpha-globin gene cluster.
|
Proc Natl Acad Sci U S A
|
2001
|
1.57
|
20
|
Histone deacetylases: complex transducers of nuclear signals.
|
Semin Cell Dev Biol
|
1999
|
1.57
|
21
|
DNA methylation is linked to deacetylation of histone H3, but not H4, on the imprinted genes Snrpn and U2af1-rs1.
|
Mol Cell Biol
|
2001
|
1.55
|
22
|
Vestiges of a DNA methylation system in Drosophila melanogaster?
|
Nat Genet
|
1999
|
1.44
|
23
|
Distinctive patterns of histone H4 acetylation are associated with defined sequence elements within both heterochromatic and euchromatic regions of the human genome.
|
Nucleic Acids Res
|
1998
|
1.31
|
24
|
Preparation of site-specific antibodies to acetylated histones.
|
Methods
|
1999
|
1.31
|
25
|
Chromatin remodeling at the Ig loci prior to V(D)J recombination.
|
J Immunol
|
2001
|
1.29
|
26
|
Deacetylase activity associates with topoisomerase II and is necessary for etoposide-induced apoptosis.
|
J Biol Chem
|
2001
|
1.25
|
27
|
dSIR2 and dHDAC6: two novel, inhibitor-resistant deacetylases in Drosophila melanogaster.
|
Exp Cell Res
|
2001
|
1.24
|
28
|
Differential underacetylation of histones H2A, H3 and H4 on the inactive X chromosome in human female cells.
|
Hum Genet
|
1996
|
1.24
|
29
|
Immunoprecipitation of chromatin.
|
Methods Enzymol
|
1996
|
1.19
|
30
|
Arylsulfatase B deficiency in Maroteaux-Lamy syndrome: Cellular studies and carrier identification.
|
Pediatr Res
|
1975
|
1.13
|
31
|
A developmental switch in H4 acetylation upstream of Xist plays a role in X chromosome inactivation.
|
EMBO J
|
1999
|
1.13
|
32
|
Histone acetylation and X inactivation.
|
Dev Genet
|
1998
|
1.10
|
33
|
An association between the kinetic and electrophoretic properties of human purine-nucleoside-phosphorylase isozymes.
|
Eur J Biochem
|
1971
|
1.10
|
34
|
Temporally restricted spatial localization of acetylated isoforms of histone H4 and RNA polymerase II in the 2-cell mouse embryo.
|
Development
|
1995
|
1.09
|
35
|
Polymorphism of human alpha fucosidase.
|
Am J Hum Genet
|
1975
|
1.09
|
36
|
Isozymes of human alpha-L-fucosidase detectable by starch gel electrophoresis.
|
Clin Chim Acta
|
1974
|
1.09
|
37
|
Evolution of dosage compensation.
|
Chromosome Res
|
1996
|
1.08
|
38
|
Selective use of H4 acetylation sites in the yeast Saccharomyces cerevisiae.
|
Biochem J
|
1993
|
1.05
|
39
|
Histone underacetylation is an ancient component of mammalian X chromosome inactivation.
|
Proc Natl Acad Sci U S A
|
1997
|
1.05
|
40
|
Cell-specific differences in membrane beta-glucosidase from normal and Gaucher cells.
|
Biochim Biophys Acta
|
1977
|
1.01
|
41
|
Molecular cloning of Drosophila melanogaster cDNAs that encode a novel histone deacetylase dHDAC3.
|
Gene
|
1998
|
1.00
|
42
|
Histone H4 acetylated at lysine 16 and proteins of the Drosophila dosage compensation pathway co-localize on the male X chromosome through mitosis.
|
Chromosome Res
|
1994
|
0.97
|
43
|
Improved sample extraction before liquid chromatography of prednisone and prednisolone in human serum.
|
Clin Chem
|
1982
|
0.97
|
44
|
Histone H4 acetylation and replication timing in Chinese hamster chromosomes.
|
Exp Cell Res
|
1996
|
0.94
|
45
|
Characterization of a family of nuclear and chromosomal proteins identified by a monoclonal antibody.
|
Eur J Cell Biol
|
1985
|
0.93
|
46
|
Properties of beta-glucosidase in cultured skin fibroblasts from controls and patients with Gaucher disease.
|
Am J Hum Genet
|
1978
|
0.93
|
47
|
Assignment of the gene locus for human alpha-L-fucosidase to chromosome 1 by analysis of somatic cell hybrids.
|
Somatic Cell Genet
|
1978
|
0.93
|
48
|
Histone H4 acetylation and transcription in amphibian chromatin.
|
J Cell Biol
|
1993
|
0.91
|
49
|
The use of alkaline-phosphatase-conjugated second antibody for the visualization of electrophoretically separated proteins recognized by monoclonal antibodies.
|
J Immunol Methods
|
1983
|
0.91
|
50
|
Stage-dependent redistributions of acetylated histones in nuclei of the early preimplantation mouse embryo.
|
Mol Reprod Dev
|
1997
|
0.91
|
51
|
Temperature regulation during wakefulness, sleep, and hibernation in marmots.
|
Am J Physiol
|
1978
|
0.90
|
52
|
H4 acetylation, XIST RNA and replication timing are coincident and define x;autosome boundaries in two abnormal X chromosomes.
|
Hum Mol Genet
|
1999
|
0.90
|
53
|
Histone H4 acetylation in Drosophila. Frequency of acetylation at different sites defined by immunolabelling with site-specific antibodies.
|
FEBS Lett
|
1991
|
0.88
|
54
|
Differential immunostaining of plant chromosomes by antibodies recognizing acetylated histone H4 variants.
|
Chromosome Res
|
1996
|
0.87
|
55
|
The age related loss of activity of four enzymes in the human erythrocyte.
|
Clin Chim Acta
|
1974
|
0.87
|
56
|
Maternal histone deacetylase is accumulated in the nuclei of Xenopus oocytes as protein complexes with potential enzyme activity.
|
J Cell Sci
|
1999
|
0.87
|
57
|
Characterization of monoclonal antibodies to histone 2B. Localization of epitopes and analysis of binding to chromatin.
|
Eur J Biochem
|
1986
|
0.86
|
58
|
Human inosine triphosphatase: catalytic properties and population studies.
|
Clin Chim Acta
|
1979
|
0.85
|
59
|
Chromatin structure analysis of the mouse Xist locus.
|
Proc Natl Acad Sci U S A
|
1999
|
0.85
|
60
|
Silent allele as genetic basis of fucosidosis.
|
Nature
|
1975
|
0.84
|
61
|
Different strategies of X-inactivation in germinal and somatic cells: histone H4 underacetylation does not mark the inactive X chromosome in the mouse male germline.
|
Exp Cell Res
|
1997
|
0.82
|
62
|
Individual variation in the isotype profile of anti-histone autoantibodies in systemic lupus erythematosus.
|
Clin Exp Immunol
|
1988
|
0.82
|
63
|
Secretion of alpha 1-antitrypsin by an established human hepatoma cell line and by human/mouse hybrids.
|
Somatic Cell Genet
|
1980
|
0.82
|
64
|
Use of alkaline phosphatase-conjugated antibodies for detection of protein antigens on nitrocellulose filters.
|
Methods Enzymol
|
1986
|
0.82
|
65
|
Correlation between clinical features of systemic lupus erythematosus and levels of antihistone antibodies of the IgG, IgA, and IgM isotypes.
|
Ann Rheum Dis
|
1990
|
0.81
|
66
|
alpha-L-fucosidase in cultured skin fibroblasts from normal subjects and fucosidosis patients.
|
Pediatr Res
|
1977
|
0.81
|
67
|
An account of two new ICD-S variants not detectable in red blood cells.
|
Ann Hum Genet
|
1974
|
0.80
|
68
|
A monoclonal antibody recognizes a phosphorylated epitope shared by proteins of the cell nucleus and the erythrocyte membrane skeleton.
|
FEBS Lett
|
1986
|
0.80
|
69
|
Euchromatic domains in plant chromosomes as revealed by H4 histone acetylation and early DNA replication.
|
Genome
|
1999
|
0.80
|
70
|
Tomographic distribution of acetylated histone H4 in plant chromosomes, nuclei and nucleoli.
|
Chromosoma
|
1996
|
0.80
|
71
|
Studies on human erythrocyte inorganic pyrophosphatase.
|
Ann Hum Genet
|
1974
|
0.79
|
72
|
Isolation of monoclonal antibodies to chromatin and preliminary characterization of target antigens.
|
Eur J Cell Biol
|
1981
|
0.79
|
73
|
Immunofluorescent staining of human metaphase chromosomes with monoclonal antibody to histone H2B.
|
Chromosoma
|
1982
|
0.79
|
74
|
Immunocytochemical localization of cytoskeletal proteins and histone 2B in isolated membrane-depleted nuclei, metaphase chromatin, and whole Chinese hamster ovary cells.
|
J Histochem Cytochem
|
1983
|
0.79
|
75
|
alpha-L-Fucosidase in normal and deficient individuals.
|
Adv Exp Med Biol
|
1976
|
0.78
|
76
|
Purification and characterisation of alpha-L-fucosidase from human placenta. pH-dependent changes in molecular size.
|
Biochim Biophys Acta
|
1979
|
0.78
|
77
|
Hepatorenal toxicity following fluroxene anesthesia.
|
Anesthesiology
|
1973
|
0.78
|
78
|
Muscle recruitment patterns regulate physiological responses during exercise of the same intensity.
|
Am J Physiol Regul Integr Comp Physiol
|
2000
|
0.77
|
79
|
A correlation between DNA-nuclear matrix binding and relative radiosensitivity in two human squamous cell carcinoma cell lines.
|
Int J Radiat Biol
|
1993
|
0.77
|
80
|
Fucosidosis: detection of the carrier state in peripheral blood leukocytes.
|
J Pediatr
|
1975
|
0.76
|
81
|
Immunofluorescent localisation of cytokeratin antigens in mitotic HeLa cells using monoclonal antibodies.
|
Eur J Cell Biol
|
1985
|
0.76
|
82
|
Suppression of heat-shock protein synthesis by short-chain fatty acids and alcohols.
|
Biochim Biophys Acta
|
1994
|
0.76
|
83
|
Changes to the BVA/KC Canine Health Schemes.
|
Vet Rec
|
2010
|
0.75
|
84
|
A monoclonal antibody identifies a 215 000-dalton nuclear envelope protein restricted to certain cell types.
|
Eur J Cell Biol
|
1985
|
0.75
|
85
|
Assignment of the human alpha-L-fucosidase gene locus to chromosome 1 by use of a "clone panel".
|
Cytogenet Cell Genet
|
1976
|
0.75
|
86
|
Assignment of the human alpha-l-fucosidase gene locus to chromosome 1 by use of a "clone panel".
|
Birth Defects Orig Artic Ser
|
1976
|
0.75
|
87
|
The pattern of histone H4 acetylation on the X chromosome during spermatogenesis of the desert locust Schistocerca gregaria.
|
Genome
|
1996
|
0.75
|
88
|
Antibody labelling and flow cytometric analysis of metaphase chromosomes reveals two discrete structural forms.
|
Chromosoma
|
1987
|
0.75
|
89
|
Terrorism and EMS: a security issue.
|
JEMS
|
1982
|
0.75
|
90
|
Metabolic correction of fucosidosis fibroblasts by human alpha-L-fucosidase.
|
J Cell Physiol
|
1979
|
0.75
|
91
|
A comparison of the soluble and mitochondrial forms of human isocitrate dehydrogenase and an examination of the secondary isozymes derived from the soluble form.
|
Ann Hum Genet
|
1974
|
0.75
|
92
|
Regional localization of HLA, MES, and SODM on chromosome 6.
|
Cytogenet Cell Genet
|
1978
|
0.75
|
93
|
Windows of vulnerability.
|
JEMS
|
1983
|
0.75
|
94
|
An investigation of some factors affecting levels of erythrocyte inorganic pyrophosphatase activity.
|
Clin Chim Acta
|
1975
|
0.75
|
95
|
Preparation of insect chromosomes for immunolabeling.
|
Biotech Histochem
|
1996
|
0.75
|
96
|
Human beta-glucosidase: inhibition by sulphates and purification by affinity chromatography on Dextran-sulphate-Sepharose.
|
Biochim Biophys Acta
|
1981
|
0.75
|