Histone H4 acetylation distinguishes coding regions of the human genome from heterochromatin in a differentiation-dependent but transcription-independent manner.

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Published in EMBO J on August 15, 1995

Authors

L P O'Neill1, B M Turner

Author Affiliations

1: Anatomy Department, University of Birmingham Medical School, Edgbaston, UK.

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Individual variation in the isotype profile of anti-histone autoantibodies in systemic lupus erythematosus. Clin Exp Immunol (1988) 0.82

alpha-L-fucosidase in cultured skin fibroblasts from normal subjects and fucosidosis patients. Pediatr Res (1977) 0.81

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An account of two new ICD-S variants not detectable in red blood cells. Ann Hum Genet (1974) 0.80

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Immunofluorescent staining of human metaphase chromosomes with monoclonal antibody to histone H2B. Chromosoma (1982) 0.79

Studies on human erythrocyte inorganic pyrophosphatase. Ann Hum Genet (1974) 0.79

Immunocytochemical localization of cytoskeletal proteins and histone 2B in isolated membrane-depleted nuclei, metaphase chromatin, and whole Chinese hamster ovary cells. J Histochem Cytochem (1983) 0.79

Isolation of monoclonal antibodies to chromatin and preliminary characterization of target antigens. Eur J Cell Biol (1981) 0.79

Hepatorenal toxicity following fluroxene anesthesia. Anesthesiology (1973) 0.78

Purification and characterisation of alpha-L-fucosidase from human placenta. pH-dependent changes in molecular size. Biochim Biophys Acta (1979) 0.78

alpha-L-Fucosidase in normal and deficient individuals. Adv Exp Med Biol (1976) 0.78

A correlation between DNA-nuclear matrix binding and relative radiosensitivity in two human squamous cell carcinoma cell lines. Int J Radiat Biol (1993) 0.77

Muscle recruitment patterns regulate physiological responses during exercise of the same intensity. Am J Physiol Regul Integr Comp Physiol (2000) 0.77

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Assignment of the human alpha-L-fucosidase gene locus to chromosome 1 by use of a "clone panel". Cytogenet Cell Genet (1976) 0.75

Terrorism and EMS: a security issue. JEMS (1982) 0.75

Assignment of the human alpha-l-fucosidase gene locus to chromosome 1 by use of a "clone panel". Birth Defects Orig Artic Ser (1976) 0.75

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Windows of vulnerability. JEMS (1983) 0.75

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