Structural insight into human Zn(2+)-bound S100A2 from NMR and homology modeling.

Implication of extracellular zinc exclusion by recombinant human calprotectin (MRP8 and MRP14) from target cells in its apoptosis-inducing activity. Mediators Inflamm (2002) 1.03

Both Ca2+ and Zn2+ are essential for S100A12 protein oligomerization and function. BMC Biochem (2009) 1.03

Structural characterization of human S100A16, a low-affinity calcium binder. J Biol Inorg Chem (2010) 0.82

Purification and crystallization of the human EF-hand tumour suppressor protein S100A2. Acta Crystallogr Sect F Struct Biol Cryst Commun (2006) 0.78

VITAL NMR: using chemical shift derived secondary structure information for a limited set of amino acids to assess homology model accuracy. J Biomol NMR (2011) 0.75

The S100 family of EF-hand calcium-binding proteins: functions and pathology. Trends Biochem Sci (1996) 4.63

New insights to the MLL recombinome of acute leukemias. Leukemia (2009) 4.07

Minimal residual disease-directed risk stratification using real-time quantitative PCR analysis of immunoglobulin and T-cell receptor gene rearrangements in the international multicenter trial AIEOP-BFM ALL 2000 for childhood acute lymphoblastic leukemia. Leukemia (2008) 3.23

Structural basis for the recognition of DNA repair proteins UNG2, XPA, and RAD52 by replication factor RPA. Cell (2000) 2.73

The MLL recombinome of acute leukemias in 2013. Leukemia (2013) 2.55

Rotational diffusion anisotropy of proteins from simultaneous analysis of 15N and 13C alpha nuclear spin relaxation. J Biomol NMR (1997) 2.18

Correlation of parvalbumin concentration with relaxation speed in mammalian muscles. Proc Natl Acad Sci U S A (1982) 1.93

Two classes of cortical GABA neurons defined by differential calcium binding protein immunoreactivities. Exp Brain Res (1989) 1.77

Zinc-reversible antimicrobial activity of recombinant calprotectin (migration inhibitory factor-related proteins 8 and 14). J Infect Dis (2000) 1.76

High level expression and dimer characterization of the S100 EF-hand proteins, migration inhibitory factor-related proteins 8 and 14. J Biol Chem (1998) 1.76

Parvalbumin-immunoreactive neurons in the rat neostriatum: a light and electron microscopic study. Brain Res (1990) 1.58

Isolation of a YAC clone covering a cluster of nine S100 genes on human chromosome 1q21: rationale for a new nomenclature of the S100 calcium-binding protein family. Genomics (1995) 1.54

Inverse expression of S100A4 and E-cadherin is associated with metastatic potential in gastric cancer. Clin Cancer Res (2000) 1.51

The MLL recombinome of acute leukemias. Leukemia (2006) 1.51

Backbone dynamics of calcium-loaded calbindin D9k studied by two-dimensional proton-detected 15N NMR spectroscopy. Biochemistry (1992) 1.50

Parvalbumin, an intracellular calcium-binding protein; distribution, properties and possible roles in mammalian cells. Experientia (1984) 1.48

Quantitative analysis of neurons and glial cells in the rat somatosensory cortex, with special reference to GABAergic neurons and parvalbumin-containing neurons. Exp Brain Res (1992) 1.48

Calcium-binding protein parvalbumin as a neuronal marker. Nature (1981) 1.45

Calcium-binding protein parvalbumin is associated with fast contracting muscle fibres. Nature (1982) 1.44

Fast spiking cells in rat hippocampus (CA1 region) contain the calcium-binding protein parvalbumin. Brain Res (1987) 1.44

GABAergic neurons containing the Ca2+-binding protein parvalbumin in the rat hippocampus and dentate gyrus. Brain Res (1987) 1.44

Calcium regulation of Ndr protein kinase mediated by S100 calcium-binding proteins. EMBO J (1998) 1.43

Structures of EF-hand Ca(2+)-binding proteins: diversity in the organization, packing and response to Ca2+ binding. Biometals (1998) 1.43

PAX3 is expressed in human melanomas and contributes to tumor cell survival. Cancer Res (2001) 1.42

Induction of apoptosis in rhabdomyosarcoma cells through down-regulation of PAX proteins. Proc Natl Acad Sci U S A (1996) 1.41

In vivo amplification of the PAX3-FKHR and PAX7-FKHR fusion genes in alveolar rhabdomyosarcoma. Hum Mol Genet (1996) 1.37

Subpopulations of GABAergic neurons in laminae I-III of rat spinal dorsal horn defined by coexistence with classical transmitters, peptides, nitric oxide synthase or parvalbumin. Neuroscience (1994) 1.36

An interaction-based analysis of calcium-induced conformational changes in Ca2+ sensor proteins. Protein Sci (1998) 1.35

Six S100 genes are clustered on human chromosome 1q21: identification of two genes coding for the two previously unreported calcium-binding proteins S100D and S100E. Proc Natl Acad Sci U S A (1993) 1.30

Altered expression of the Ca(2+)-binding protein S100A1 in human cardiomyopathy. Biochim Biophys Acta (1996) 1.29

Determination of the solution structure of Apo calbindin D9k by NMR spectroscopy. J Mol Biol (1995) 1.27

Expression pattern of S100 calcium-binding proteins in human tumors. Int J Cancer (1996) 1.26

PAX3 and PAX7 exhibit conserved cis-acting transcription repression domains and utilize a common gain of function mechanism in alveolar rhabdomyosarcoma. Oncogene (1999) 1.25

Effects of ion binding on the backbone dynamics of calbindin D9k determined by 15N NMR relaxation. Biochemistry (1993) 1.25

Analysis of myosin light and heavy chain types in single human skeletal muscle fibers. Eur J Biochem (1981) 1.24

Intramolecular activation of a Ca(2+)-dependent protein kinase is disrupted by insertions in the tether that connects the calmodulin-like domain to the kinase. Biochemistry (2000) 1.24

Crossover isomer bias is the primary sequence-dependent property of immobilized Holliday junctions. Proc Natl Acad Sci U S A (1997) 1.24

Three-dimensional structure of 6-pyruvoyl tetrahydropterin synthase, an enzyme involved in tetrahydrobiopterin biosynthesis. EMBO J (1994) 1.23

Transcriptional modulation of the anti-apoptotic protein BCL-XL by the paired box transcription factors PAX3 and PAX3/FKHR. Oncogene (2000) 1.22

Distinct subcellular localization of calcium binding S100 proteins in human smooth muscle cells and their relocation in response to rises in intracellular calcium. J Cell Sci (1998) 1.22

DRAL is a p53-responsive gene whose four and a half LIM domain protein product induces apoptosis. J Cell Biol (2000) 1.21

The structure of calcyclin reveals a novel homodimeric fold for S100 Ca(2+)-binding proteins. Nat Struct Biol (1995) 1.19

Clinical significance of S100A4 and E-cadherin-related adhesion molecules in non-small cell lung cancer. Int J Oncol (2000) 1.18

Phenylalanine hydroxylase-stimulating protein/pterin-4 alpha-carbinolamine dehydratase from rat and human liver. Purification, characterization, and complete amino acid sequence. J Biol Chem (1993) 1.18

Site-site communication in the EF-hand Ca2+-binding protein calbindin D9k. Nat Struct Biol (2000) 1.18

Subtractive cloning and characterization of DRAL, a novel LIM-domain protein down-regulated in rhabdomyosarcoma. DNA Cell Biol (1997) 1.18

Signal transduction versus buffering activity in Ca(2+)-binding proteins. Nat Struct Biol (1994) 1.17

Solution structure of (Cd2+)1-calbindin D9k reveals details of the stepwise structural changes along the Apo-->(Ca2+)II1-->(Ca2+)I,II2 binding pathway. J Mol Biol (1995) 1.16

Comparative expression profiling identifies an in vivo target gene signature with TFAP2B as a mediator of the survival function of PAX3/FKHR. Oncogene (2007) 1.16

Chemically defined neuron groups and their subpopulations in the glomerular layer of the rat main olfactory bulb. Neurosci Res (1995) 1.16

Cell-specific immuno-probes for the brain of normal and mutant Drosophila melanogaster. I. Wildtype visual system. Cell Tissue Res (1988) 1.16

Axons and axon terminals of cerebellar Purkinje cells and basket cells have higher levels of parvalbumin immunoreactivity than somata and dendrites: quantitative analysis by immunogold labeling. Exp Brain Res (1993) 1.15

Isolation of genes differentially expressed in human primary myoblasts and embryonal rhabdomyosarcoma. Int J Cancer (1996) 1.14

Immunocytochemical study of GABAergic neurons containing the calcium-binding protein parvalbumin in the rat hippocampus. Exp Brain Res (1988) 1.14

Increased expression of S100A4 and its prognostic significance in esophageal squamous cell carcinoma. Int J Oncol (2001) 1.14

6-Pyruvoyl tetrahydropterin synthase, an enzyme with a novel type of active site involving both zinc binding and an intersubunit catalytic triad motif; site-directed mutagenesis of the proposed active center, characterization of the metal binding site and modelling of substrate binding. J Mol Biol (1995) 1.13

Gap junctions on GABAergic neurons containing the calcium-binding protein parvalbumin in the rat hippocampus (CA1 region). Exp Brain Res (1988) 1.10

Supratentorial pilocytic astrocytomas, astrocytomas, anaplastic astrocytomas and glioblastomas are characterized by a differential expression of S100 proteins. Brain Pathol (1999) 1.08

Immunohistochemical localization of the Ca2+ binding S100 proteins in normal human skin and melanocytic lesions. Br J Dermatol (1997) 1.08

1H nuclear magnetic resonance assignments for d-(GCATTAATGC)2 using experimental refinements of established procedures. J Mol Biol (1986) 1.08

Repression of the candidate tumor suppressor gene S100A2 in breast cancer is mediated by site-specific hypermethylation. Cell Calcium (1997) 1.07

The three-dimensional structure of Ca(2+)-bound calcyclin: implications for Ca(2+)-signal transduction by S100 proteins. Structure (1998) 1.07

Different populations of parvalbumin- and calbindin-D28k-immunoreactive neurons contain GABA and accumulate 3H-D-aspartate in the dorsal horn of the rat spinal cord. J Comp Neurol (1991) 1.06

Direct evidence of an extensive GABAergic innervation of the spinal dorsal horn by fibres descending from the rostral ventromedial medulla. Neuroscience (1996) 1.06

High-resolution structure of calcium-loaded calbindin D9k. J Mol Biol (1993) 1.06

Nuclear magnetic resonance studies of the internal dynamics in Apo, (Cd2+)1 and (Ca2+)2 calbindin D9k. The rates of amide proton exchange with solvent. J Mol Biol (1992) 1.05

Solution structure and dynamics of yeast elongin C in complex with a von Hippel-Lindau peptide. J Mol Biol (2001) 1.04

Parvalbumin and calbindin D-28k in the human motor system and in motor neuron disease. Neuropathol Appl Neurobiol (1993) 1.04

Clustered organization of S100 genes in human and mouse. Biochim Biophys Acta (1998) 1.04

Loss of calbindin-28K immunoreactive neurones from the cortex in Alzheimer-type dementia. Brain Res (1988) 1.04

Glyceraldehyde-3-phosphate dehydrogenase is a nonhistone protein and a possible activator of transcription in neurons. J Neurochem (1986) 1.03

Systematic analysis of molecular defects in the ferrochelatase gene from patients with erythropoietic protoporphyria. Am J Hum Genet (1998) 1.03

Binding of elongin A or a von Hippel-Lindau peptide stabilizes the structure of yeast elongin C. Proc Natl Acad Sci U S A (1999) 1.02

Expression of Ca(2+)-binding proteins of the S100 family in malignant human breast-cancer cell lines and biopsy samples. Int J Cancer (1994) 1.02

Intracellular Ca2+ and Zn2+ levels regulate the alternative cell density-dependent secretion of S100B in human glioblastoma cells. J Biol Chem (2001) 1.02

Conformational studies of d-(AAAAATTTTT)2 using constraints from nuclear overhauser effects and from quantitative analysis of the cross-peak fine structures in two-dimensional 1H nuclear magnetic resonance spectra. Biochemistry (1989) 1.01

NMR studies of the complex between the decadeoxynucleotide d-(GCATTAATGC)2 and a minor-groove-binding drug. Biochemistry (1986) 1.01

S100 alpha, CAPL, and CACY: molecular cloning and expression analysis of three calcium-binding proteins from human heart. Biochemistry (1992) 1.01

Human carbonyl and aldose reductases: new catalytic functions in tetrahydrobiopterin biosynthesis. Biochem Biophys Res Commun (1991) 1.01

Parvalbumin-containing GABAergic interneurons in the rat neostriatum. J Comp Neurol (1990) 1.01

Demonstration of heterodimer formation between S100B and S100A6 in the yeast two-hybrid system and human melanoma. Exp Cell Res (1999) 1.00

Primary structure of parvalbumin from rat skeletal muscle. Eur J Biochem (1982) 1.00

Three-dimensional structure and function of replication protein A. Cold Spring Harb Symp Quant Biol (2000) 1.00

Subversion of antimicrobial calprotectin (S100A8/S100A9 complex) in the cytoplasm of TR146 epithelial cells after invasion by Listeria monocytogenes. Mucosal Immunol (2008) 1.00

Differential expression of S100B and S100A6(1) in the human fetal and aged cerebral cortex. Brain Res Dev Brain Res (2000) 1.00

Lack of copper insertion into unprocessed cytoplasmic nitrous oxide reductase generated by an R20D substitution in the arginine consensus motif of the signal peptide. Biochim Biophys Acta (1997) 1.00

Localization of Ca(2+)-binding S100 proteins in epithelial tumours of the skin. Virchows Arch (1998) 1.00