Published in Cancer Res on October 15, 2001
Spatiotemporal regulation of epithelial-mesenchymal transition is essential for squamous cell carcinoma metastasis. Cancer Cell (2012) 4.51
Loss of TGFbeta signaling destabilizes homeostasis and promotes squamous cell carcinomas in stratified epithelia. Cancer Cell (2007) 3.55
Cooperation of the ErbB2 receptor and transforming growth factor beta in induction of migration and invasion in mammary epithelial cells. Proc Natl Acad Sci U S A (2004) 2.81
Autocrine PDGFR signaling promotes mammary cancer metastasis. J Clin Invest (2006) 2.68
Distinct mechanisms of TGF-beta1-mediated epithelial-to-mesenchymal transition and metastasis during skin carcinogenesis. J Clin Invest (2005) 1.98
Complexities of TGF-β targeted cancer therapy. Int J Biol Sci (2012) 1.84
Functional proteomics approach to investigate the biological activities of cDNAs implicated in breast cancer. J Proteome Res (2006) 1.66
TGF-β - an excellent servant but a bad master. J Transl Med (2012) 1.41
PAI-1 mediates the TGF-beta1+EGF-induced "scatter" response in transformed human keratinocytes. J Invest Dermatol (2010) 1.13
Molecular mechanisms of mouse skin tumor promotion. Cancers (Basel) (2010) 1.09
TGFβ signaling in head and neck squamous cell carcinoma. Oncogene (2010) 1.08
Transforming growth factor-beta facilitates breast carcinoma metastasis by promoting tumor cell survival. Clin Exp Metastasis (2004) 1.03
Expression of matrix metalloproteinases (MMP-2 and MMP-9) in recurrent respiratory papillomas and laryngeal carcinoma: clinical and morphological parallels. Eur Arch Otorhinolaryngol (2011) 0.98
HGF upregulation contributes to angiogenesis in mice with keratinocyte-specific Smad2 deletion. J Clin Invest (2010) 0.93
Expression of laminin 5-γ2 chain in cutaneous squamous cell carcinoma and its role in tumour invasion. Br J Cancer (2011) 0.91
Integrin alpha3beta1 potentiates TGFbeta-mediated induction of MMP-9 in immortalized keratinocytes. J Invest Dermatol (2007) 0.90
Preconditioning of mesenchymal stem cells for improved transplantation efficacy in recessive dystrophic epidermolysis bullosa. Stem Cell Res Ther (2014) 0.89
Tumor suppressor and oncogene actions of TGFbeta1 occur early in skin carcinogenesis and are mediated by Smad3. Mol Carcinog (2009) 0.83
Pro-oncogenic and anti-oncogenic pathways: opportunities and challenges of cancer therapy. Future Oncol (2010) 0.82
Transforming growth factor beta1 enhances tumor promotion in mouse skin carcinogenesis. Carcinogenesis (2010) 0.81
The complexities of TGF-β action during mammary and squamous cell carcinogenesis. Curr Pharm Biotechnol (2011) 0.81
Bronchioloalveolar invasion in non-small cell lung cancer is associated with expression of transforming growth factor-β1. World J Surg Oncol (2013) 0.80
Desmoplasia in different degrees of invasion of carcinoma ex-pleomorphic adenoma. Head Neck Pathol (2007) 0.80
The Role of TGFβ Signaling in Squamous Cell Cancer: Lessons from Mouse Models. J Skin Cancer (2012) 0.80
Pharmacologic inhibition of ALK5 causes selective induction of terminal differentiation in mouse keratinocytes expressing oncogenic HRAS. Mol Cancer Res (2011) 0.78
Transforming growth factor-Beta and urokinase-type plasminogen activator: dangerous partners in tumorigenesis-implications in skin cancer. ISRN Dermatol (2013) 0.77
Targeting TGF-β1 inhibits invasion of anaplastic thyroid carcinoma cell through SMAD2-dependent S100A4-MMP-2/9 signalling. Am J Transl Res (2016) 0.75
Quantitative liver proteomics identifies FGF19 targets that couple metabolism and proliferation. PLoS One (2017) 0.75
p63 is a p53 homologue required for limb and epidermal morphogenesis. Nature (1999) 13.21
Molecular cloning of APRF, a novel IFN-stimulated gene factor 3 p91-related transcription factor involved in the gp130-mediated signaling pathway. Cell (1994) 6.45
Yeast Sm-like proteins function in mRNA decapping and decay. Nature (2000) 5.95
Timing of CNS cell generation: a programmed sequence of neuron and glial cell production from isolated murine cortical stem cells. Neuron (2000) 3.99
Synaptic mechanisms and network dynamics underlying spatial working memory in a cortical network model. Cereb Cortex (2000) 3.80
AUX/IAA proteins are active repressors, and their stability and activity are modulated by auxin. Plant Cell (2001) 3.42
Patterns of nucleotide misincorporations during enzymatic amplification and direct large-scale sequencing of ancient DNA. Proc Natl Acad Sci U S A (2006) 3.40
Theta oscillations in somata and dendrites of hippocampal pyramidal cells in vivo: activity-dependent phase-precession of action potentials. Hippocampus (1998) 3.23
Effects of neuromodulation in a cortical network model of object working memory dominated by recurrent inhibition. J Comput Neurosci (2001) 3.16
Slowed recovery of rod photoresponse in mice lacking the GTPase accelerating protein RGS9-1. Nature (2000) 3.11
Deregulated expression of c-Myc depletes epidermal stem cells. Nat Genet (2001) 3.00
Improved insulin-sensitivity in mice heterozygous for PPAR-gamma deficiency. J Clin Invest (2000) 2.67
The human homologue of the yeast proteins Skb1 and Hsl7p interacts with Jak kinases and contains protein methyltransferase activity. J Biol Chem (1999) 2.64
A randomized trial comparing fluconazole with clotrimazole troches for the prevention of fungal infections in patients with advanced human immunodeficiency virus infection. NIAID AIDS Clinical Trials Group. N Engl J Med (1995) 2.29
A role for NMDA-receptor channels in working memory. Nat Neurosci (1998) 2.28
An antagonist peptide-EPO receptor complex suggests that receptor dimerization is not sufficient for activation. Nat Struct Biol (1998) 2.24
Birth weight and subsequent risk of obesity: a systematic review and meta-analysis. Obes Rev (2011) 2.22
Structural determinants for regulation of phosphodiesterase by a G protein at 2.0 A. Nature (2001) 2.20
CpG ODN-induced matrix metalloproteinase-13 expression is mediated via activation of the ERK and NF-κB signalling pathways in odontoblast cells. Int Endod J (2013) 2.03
Loss of presenilin 1 is associated with enhanced beta-catenin signaling and skin tumorigenesis. Proc Natl Acad Sci U S A (2001) 2.00
A randomized trial of three antipneumocystis agents in patients with advanced human immunodeficiency virus infection. NIAID AIDS Clinical Trials Group. N Engl J Med (1995) 1.89
Down-regulation of p63 is required for epidermal UV-B-induced apoptosis. Cancer Res (2000) 1.88
Identification of Arabidopsis histone deacetylase HDA6 mutants that affect transgene expression. Plant Cell (2001) 1.87
Cabin 1, a negative regulator for calcineurin signaling in T lymphocytes. Immunity (1998) 1.85
Gender differences in emotional expressivity and self-regulation during early infancy. Dev Psychol (1999) 1.85
Total parenteral nutrition and bowel rest modify the metabolic response to endotoxin in humans. Ann Surg (1989) 1.79
Phosphotyrosine-dependent interaction of SHC and insulin receptor substrate 1 with the NPEY motif of the insulin receptor via a novel non-SH2 domain. Mol Cell Biol (1995) 1.77
A model of visuospatial working memory in prefrontal cortex: recurrent network and cellular bistability. J Comput Neurosci (1998) 1.68
Multiple forms of short-term plasticity at excitatory synapses in rat medial prefrontal cortex. J Neurophysiol (2000) 1.66
The autophagic paradox in cancer therapy. Oncogene (2011) 1.61
Characterization of fluid flow velocity by optical Doppler tomography. Opt Lett (1995) 1.59
The type I serine/threonine kinase receptor ActRIA (ALK2) is required for gastrulation of the mouse embryo. Development (1999) 1.59
An inducible mouse model for epidermolysis bullosa simplex: implications for gene therapy. J Cell Biol (2001) 1.55
Intrarectal administration of mCRAMP-encoding plasmid reverses exacerbated colitis in Cnlp(-/-) mice. Gene Ther (2012) 1.53
Study of the distribution of non-point source pollution in the watershed of the Miyun Reservoir, Beijing, China. Water Sci Technol (2001) 1.49
In vivo proton MRS of normal pancreas metabolites during breath-holding and free-breathing. Clin Radiol (2012) 1.48
Spike-frequency adaptation of a generalized leaky integrate-and-fire model neuron. J Comput Neurosci (2001) 1.46
Examination of reproductive aging milestones among women who carry the FMR1 premutation. Hum Reprod (2007) 1.42
Synchronization properties of spindle oscillations in a thalamic reticular nucleus model. J Neurophysiol (1994) 1.42
Prediction and confirmation of a site critical for effector regulation of RGS domain activity. Nat Struct Biol (2001) 1.42
Laboratory investigation of ecological factors influencing the environmental presence of Burkholderia pseudomallei. Microbiol Immunol (1996) 1.40
Experimental characterization of superradiance in a single-pass high-gain laser-seeded free-electron laser amplifier. Phys Rev Lett (2007) 1.39
Cloning and characterization of RGS9-2: a striatal-enriched alternatively spliced product of the RGS9 gene. J Neurosci (1999) 1.37
NAD(P)H:quinone oxidoreductase 1 deficiency increases susceptibility to benzo(a)pyrene-induced mouse skin carcinogenesis. Cancer Res (2000) 1.37
Polycyclic aromatic hydrocarbons (PAHs) in agricultural soil and vegetables from Tianjin. Sci Total Environ (2004) 1.36
A role for TGFbeta1 in langerhans cell biology. Further characterization of the epidermal Langerhans cell defect in TGFbeta1 null mice. J Clin Invest (1997) 1.35
Contamination of rivers in Tianjin, China by polycyclic aromatic hydrocarbons. Environ Pollut (2005) 1.35
Targeted overexpression of transforming growth factor alpha in the epidermis of transgenic mice elicits hyperplasia, hyperkeratosis, and spontaneous, squamous papillomas. Cell Growth Differ (1993) 1.33
Identification of a motif in the carboxyl terminus of CXCR2 that is involved in adaptin 2 binding and receptor internalization. Biochemistry (2001) 1.32
Cell-specific expression of tubby gene family members (tub, Tulp1,2, and 3) in the retina. Invest Ophthalmol Vis Sci (1999) 1.31
Determinants of accrual of women to a large, multicenter clinical trials program of human immunodeficiency virus infection. The AIDS Clinical Trials Group. J Acquir Immune Defic Syndr (1993) 1.31
Association of copy number variation in the FCGR3B gene with risk of autoimmune diseases. Genes Immun (2009) 1.29
Targeting expression of a dominant-negative retinoic acid receptor mutant in the epidermis of transgenic mice results in loss of barrier function. Genes Dev (1995) 1.29
Elevated plasma chitotriosidase activity in various lysosomal storage disorders. J Inherit Metab Dis (1995) 1.28
Characterization of an inducible, epidermal-specific knockout system: differential expression of lacZ in different Cre reporter mouse strains. Genesis (2000) 1.23
Source apportionment of polycyclic aromatic hydrocarbons in surface soil in Tianjin, China. Environ Pollut (2006) 1.22
NAD(P)H:quinone oxidoreductase 1 deficiency and increased susceptibility to 7,12-dimethylbenz[a]-anthracene-induced carcinogenesis in mouse skin. J Natl Cancer Inst (2001) 1.21
Co-expression of Gbeta5 enhances the function of two Ggamma subunit-like domain-containing regulators of G protein signaling proteins. J Biol Chem (2000) 1.19
The influence of sperm morphology and the number of motile sperm inseminated on the outcome of intrauterine insemination combined with mild ovarian stimulation. Fertil Steril (1996) 1.19
Failure of body mass index or body weight to influence markedly the response to ovarian hyperstimulation in normal cycling women. Fertil Steril (1990) 1.17
Modulation of gastrointestinal function by MuDelta, a mixed µ opioid receptor agonist/ µ opioid receptor antagonist. Br J Pharmacol (2012) 1.16
A regulator of G protein signaling interaction surface linked to effector specificity. Proc Natl Acad Sci U S A (2000) 1.15
Oxidative stress-induced phospholipase C-gamma 1 activation enhances cell survival. J Biol Chem (2001) 1.15
Characterization of unique amphipathic antimicrobial peptides from venom of the scorpion Pandinus imperator. Biochem J (2001) 1.14
Ionic basis for intrinsic 40 Hz neuronal oscillations. Neuroreport (1993) 1.13
Amino acid sequence of rat kidney glutathione synthetase. Proc Natl Acad Sci U S A (1995) 1.13
Smads mediate signaling of the TGFbeta superfamily in normal keratinocytes but are lost during skin chemical carcinogenesis. Oncogene (2001) 1.11
Micromanipulation of mitotic chromosomes in PTK2 cells using laser-induced optical forces ("optical tweezers"). Exp Cell Res (1991) 1.09
Exponential gain and saturation of a self-amplified spontaneous emission free-electron laser. Science (2001) 1.09
Associations of fat mass and fat distribution with bone mineral density in pre- and postmenopausal Chinese women. Osteoporos Int (2010) 1.09
Hepatitis C virus replication is directly inhibited by IFN-alpha in a full-length binary expression system. Proc Natl Acad Sci U S A (2001) 1.07
Anti-Mullerian hormone indicates early ovarian decline in fragile X mental retardation (FMR1) premutation carriers: a preliminary study. Hum Reprod (2008) 1.07
Inhibition by furosemide of inflammatory mediators from lung fragments. N Engl J Med (1991) 1.07
Structure, alternative splicing, and expression of the human RGS9 gene. Gene (1999) 1.05
Focal activation of a mutant allele defines the role of stem cells in mosaic skin disorders. J Cell Biol (2001) 1.05
Human keratin-1.bcl-2 transgenic mice aberrantly express keratin 6, exhibit reduced sensitivity to keratinocyte cell death induction, and are susceptible to skin tumor formation. Oncogene (1998) 1.05
Sequencing, distribution, and inactivation of the dipeptidase A gene (pepDA) from Lactobacillus helveticus CNRZ32. J Bacteriol (1996) 1.05
Retinol-binding protein 4 is associated with impaired glucose regulation and microalbuminuria in a Chinese population. Diabetologia (2009) 1.05
A recombinant human angiostatin protein inhibits experimental primary and metastatic cancer. Cancer Res (1997) 1.04
Experimental study of coaxial free-electron maser based on two-dimensional distributed feedback. Phys Rev Lett (2006) 1.04
Targeted expression of c-Myc in the epidermis alters normal proliferation, differentiation and UV-B induced apoptosis. Oncogene (1999) 1.04
Bone marrow cells can give rise to ameloblast-like cells. J Dent Res (2006) 1.03
Increasing TB case detection through intensive referral of TB suspects by village doctors to county TB dispensaries. Int J Tuberc Lung Dis (2007) 1.03
Expressions of BAFF/BAFF receptors and their correlation with disease activity in Chinese SLE patients. Lupus (2010) 1.02
Finasteride increases anagen hair in men with androgenetic alopecia. Br J Dermatol (2000) 1.01
Temporal thresholds for neocortical infarction in rats subjected to reversible focal cerebral ischemia. Stroke (1991) 1.01
Anthropometric facial analysis of the African American woman. Arch Facial Plast Surg (2001) 1.01
Ectopic expression of an Arabidopsis calmodulin-like domain protein kinase-enhanced NADPH oxidase activity and oxidative burst in tomato protoplasts. Mol Plant Microbe Interact (2001) 1.01
Effect of soy isoflavones on blood pressure: a meta-analysis of randomized controlled trials. Nutr Metab Cardiovasc Dis (2011) 1.00
Hyperplasia, hyperkeratosis and benign tumor production in transgenic mice by a targeted v-fos oncogene suggest a role for fos in epidermal differentiation and neoplasia. Oncogene (1993) 1.00
Blocking transforming growth factor beta signaling in transgenic epidermis accelerates chemical carcinogenesis: a mechanism associated with increased angiogenesis. Cancer Res (1999) 0.99
Implications of all-or-none synaptic transmission and short-term depression beyond vesicle depletion: a computational study. J Neurosci (2000) 0.99
Micromanipulation of chromosomes in PTK2 cells using laser microsurgery (optical scalpel) in combination with laser-induced optical force (optical tweezers). Exp Cell Res (1993) 0.97
Structures at the proteolytic processing region of cathepsin D. J Biol Chem (1988) 0.97
MK-677, an orally active growth hormone secretagogue, reverses diet-induced catabolism. J Clin Endocrinol Metab (1998) 0.96
Subsyndromal depressive symptoms and major depression in postpartum women. Am J Orthopsychiatry (2001) 0.96
Strange baryon resonance production in sqrt s NN=200 GeV p+p and Au+Au collisions. Phys Rev Lett (2006) 0.96
Asymptomatic and late-onset ornithine transcarbamylase (OTC) deficiency in males of a five-generation family, caused by an A208T mutation. Clin Genet (1996) 0.95