Published in J Biol Chem on November 09, 2001
BioJava: an open-source framework for bioinformatics in 2012. Bioinformatics (2012) 2.94
The circumsphere as a tool to assess distortion in [4Fe-4S] atom clusters. J Biol Inorg Chem (2003) 0.94
Redox reactions of the iron-sulfur cluster in a ribosomal RNA methyltransferase, RumA: optical and EPR studies. J Biol Chem (2004) 0.90
The structure of the 2[4Fe-4S] ferredoxin from Pseudomonas aeruginosa at 1.32-A resolution: comparison with other high-resolution structures of ferredoxins and contributing structural features to reduction potential values. J Biol Inorg Chem (2006) 0.88
Insight into the protein and solvent contributions to the reduction potentials of [4Fe-4S]2+/+ clusters: crystal structures of the Allochromatium vinosum ferredoxin variants C57A and V13G and the homologous Escherichia coli ferredoxin. J Biol Inorg Chem (2009) 0.80
X-ray structures of the hexameric building block of the HIV capsid. Cell (2009) 4.08
The structure of human microsomal cytochrome P450 3A4 determined by X-ray crystallography to 2.05-A resolution. J Biol Chem (2004) 3.18
Investigating and exploiting the electrocatalytic properties of hydrogenases. Chem Rev (2007) 3.01
An open conformation of mammalian cytochrome P450 2B4 at 1.6-A resolution. Proc Natl Acad Sci U S A (2003) 2.74
Structure of mammalian cytochrome P450 2B4 complexed with 4-(4-chlorophenyl)imidazole at 1.9-A resolution: insight into the range of P450 conformations and the coordination of redox partner binding. J Biol Chem (2004) 2.66
Structures of human microsomal cytochrome P450 2A6 complexed with coumarin and methoxsalen. Nat Struct Mol Biol (2005) 2.54
The structure of human cytochrome P450 2C9 complexed with flurbiprofen at 2.0-A resolution. J Biol Chem (2004) 2.24
Enzymes as working or inspirational electrocatalysts for fuel cells and electrolysis. Chem Rev (2008) 2.23
Structure of human microsomal cytochrome P450 2C8. Evidence for a peripheral fatty acid binding site. J Biol Chem (2003) 2.09
Adaptations for the oxidation of polycyclic aromatic hydrocarbons exhibited by the structure of human P450 1A2. J Biol Chem (2007) 1.96
Structure of a c-kit product complex reveals the basis for kinase transactivation. J Biol Chem (2003) 1.95
Structure of microsomal cytochrome P450 2B4 complexed with the antifungal drug bifonazole: insight into P450 conformational plasticity and membrane interaction. J Biol Chem (2005) 1.91
Structure of a cofactor-deficient nitrogenase MoFe protein. Science (2002) 1.91
How Escherichia coli is equipped to oxidize hydrogen under different redox conditions. J Biol Chem (2009) 1.59
X-ray crystallographic and computational studies of the O2-tolerant [NiFe]-hydrogenase 1 from Escherichia coli. Proc Natl Acad Sci U S A (2012) 1.57
How oxygen attacks [FeFe] hydrogenases from photosynthetic organisms. Proc Natl Acad Sci U S A (2009) 1.51
A unique iron-sulfur cluster is crucial for oxygen tolerance of a [NiFe]-hydrogenase. Nat Chem Biol (2011) 1.50
Crystallographic studies of Xe and Kr binding within the large internal cavity of cytochrome ba3 from Thermus thermophilus: structural analysis and role of oxygen transport channels in the heme-Cu oxidases. Biochemistry (2008) 1.49
Structural diversity of human xenobiotic-metabolizing cytochrome P450 monooxygenases. Biochem Biophys Res Commun (2005) 1.47
The FeMoco-deficient MoFe protein produced by a nifH deletion strain of Azotobacter vinelandii shows unusual P-cluster features. J Biol Chem (2002) 1.46
Structural and kinetic analysis of the substrate specificity of human fibroblast activation protein alpha. J Biol Chem (2005) 1.44
Enzyme electrokinetics: using protein film voltammetry to investigate redox enzymes and their mechanisms. Biochemistry (2003) 1.43
Rapid and efficient electrocatalytic CO2/CO interconversions by Carboxydothermus hydrogenoformans CO dehydrogenase I on an electrode. J Am Chem Soc (2007) 1.42
Substrate recognition, protein dynamics, and iron-sulfur cluster in Pseudomonas aeruginosa adenosine 5'-phosphosulfate reductase. J Mol Biol (2006) 1.42
Visible light-driven H(2) production by hydrogenases attached to dye-sensitized TiO(2) nanoparticles. J Am Chem Soc (2009) 1.41
Crystal structures of substrate-bound and substrate-free cytochrome P450 46A1, the principal cholesterol hydroxylase in the brain. Proc Natl Acad Sci U S A (2008) 1.40
Crystal structure of CYP24A1, a mitochondrial cytochrome P450 involved in vitamin D metabolism. J Mol Biol (2009) 1.39
Structure of a substrate complex of mammalian cytochrome P450 2C5 at 2.3 A resolution: evidence for multiple substrate binding modes. Biochemistry (2003) 1.38
A novel cryoprotection scheme for enhancing the diffraction of crystals of recombinant cytochrome ba3 oxidase from Thermus thermophilus. Acta Crystallogr D Biol Crystallogr (2005) 1.36
Conformational flexibility in the flap domains of ligand-free HIV protease. Acta Crystallogr D Biol Crystallogr (2007) 1.36
A conserved mechanism for sulfonucleotide reduction. PLoS Biol (2005) 1.34
Structure of mammalian cytochrome P450 2C5 complexed with diclofenac at 2.1 A resolution: evidence for an induced fit model of substrate binding. Biochemistry (2003) 1.34
Electrochemical definitions of O2 sensitivity and oxidative inactivation in hydrogenases. J Am Chem Soc (2005) 1.33
Heterocyclic peptide backbone modifications in an alpha-helical coiled coil. J Am Chem Soc (2004) 1.33
Structure of the human lung cytochrome P450 2A13. J Biol Chem (2007) 1.33
Structural basis for the inhibition of RNase H activity of HIV-1 reverse transcriptase by RNase H active site-directed inhibitors. J Virol (2010) 1.32
Crystal structure of a cytochrome P450 2B6 genetic variant in complex with the inhibitor 4-(4-chlorophenyl)imidazole at 2.0-A resolution. Mol Pharmacol (2010) 1.32
Electrocatalytic hydrogen oxidation by an enzyme at high carbon monoxide or oxygen levels. Proc Natl Acad Sci U S A (2005) 1.30
Fragment-based screen against HIV protease. Chem Biol Drug Des (2010) 1.26
Oxygen-tolerant [NiFe]-hydrogenases: the individual and collective importance of supernumerary cysteines at the proximal Fe-S cluster. J Am Chem Soc (2011) 1.26
High resolution structure of the ba3 cytochrome c oxidase from Thermus thermophilus in a lipidic environment. PLoS One (2011) 1.23
Crystal structure of human dipeptidyl peptidase IV in complex with a decapeptide reveals details on substrate specificity and tetrahedral intermediate formation. Protein Sci (2004) 1.23
Oxygen-tolerant H2 oxidation by membrane-bound [NiFe] hydrogenases of ralstonia species. Coping with low level H2 in air. J Biol Chem (2008) 1.22
Coiled coils at the edge of configurational heterogeneity. Structural analyses of parallel and antiparallel homotetrameric coiled coils reveal configurational sensitivity to a single solvent-exposed amino acid substitution. Biochemistry (2006) 1.21
Structural basis for three-step sequential catalysis by the cholesterol side chain cleavage enzyme CYP11A1. J Biol Chem (2010) 1.20
High-resolution structure of the soluble, respiratory-type Rieske protein from Thermus thermophilus: analysis and comparison. Biochemistry (2003) 1.19
Designer laccases: a vogue for high-potential fungal enzymes? Trends Biotechnol (2009) 1.18
A stable electrode for high-potential, electrocatalytic O(2) reduction based on rational attachment of a blue copper oxidase to a graphite surface. Chem Commun (Camb) (2007) 1.18
Electrochemical potential-step investigations of the aerobic interconversions of [NiFe]-hydrogenase from Allochromatium vinosum: insights into the puzzling difference between unready and ready oxidized inactive states. J Am Chem Soc (2004) 1.18
Enzyme electrokinetics: electrochemical studies of the anaerobic interconversions between active and inactive states of Allochromatium vinosum [NiFe]-hydrogenase. J Am Chem Soc (2003) 1.18
Structural diversity of eukaryotic membrane cytochrome p450s. J Biol Chem (2013) 1.18
Instantaneous, stoichiometric generation of powerfully reducing states of protein active sites using Eu(II) and polyaminocarboxylate ligands. Chem Commun (Camb) (2003) 1.16
The difference a Se makes? Oxygen-tolerant hydrogen production by the [NiFeSe]-hydrogenase from Desulfomicrobium baculatum. J Am Chem Soc (2008) 1.15
Combined microspectrophotometric and crystallographic examination of chemically reduced and X-ray radiation-reduced forms of cytochrome ba3 oxidase from Thermus thermophilus: structure of the reduced form of the enzyme. Biochemistry (2009) 1.15
A heterocyclic peptide nanotube. J Am Chem Soc (2003) 1.14
Crystal structures of cytochrome P450 2B4 in complex with the inhibitor 1-biphenyl-4-methyl-1H-imidazole: ligand-induced structural response through alpha-helical repositioning. Biochemistry (2009) 1.14
Determinants of cytochrome P450 2C8 substrate binding: structures of complexes with montelukast, troglitazone, felodipine, and 9-cis-retinoic acid. J Biol Chem (2008) 1.14
Direct comparison of the electrocatalytic oxidation of hydrogen by an enzyme and a platinum catalyst. Chem Commun (Camb) (2002) 1.14
Crystal structure of human cytochrome P450 2D6 with prinomastat bound. J Biol Chem (2012) 1.13
A kinetic and thermodynamic understanding of O2 tolerance in [NiFe]-hydrogenases. Proc Natl Acad Sci U S A (2009) 1.13
Structural basis of drug binding to CYP46A1, an enzyme that controls cholesterol turnover in the brain. J Biol Chem (2010) 1.11
Structural and thermodynamic consequences of 1-(4-chlorophenyl)imidazole binding to cytochrome P450 2B4. Biochemistry (2007) 1.11
Structures of cytochrome P450 2B4 complexed with the antiplatelet drugs ticlopidine and clopidogrel . Biochemistry (2010) 1.10
Efficient and clean photoreduction of CO(2) to CO by enzyme-modified TiO(2) nanoparticles using visible light. J Am Chem Soc (2010) 1.09
Conformational adaptation of human cytochrome P450 2B6 and rabbit cytochrome P450 2B4 revealed upon binding multiple amlodipine molecules. Biochemistry (2012) 1.08
Plasticity of cytochrome P450 2B4 as investigated by hydrogen-deuterium exchange mass spectrometry and X-ray crystallography. J Biol Chem (2010) 1.08
Efficient electrocatalytic oxygen reduction by the 'blue' copper oxidase, laccase, directly attached to chemically modified carbons. Faraday Discuss (2008) 1.06
Structural insight into the altered substrate specificity of human cytochrome P450 2A6 mutants. Arch Biochem Biophys (2007) 1.06
Electrocatalytic mechanism of reversible hydrogen cycling by enzymes and distinctions between the major classes of hydrogenases. Proc Natl Acad Sci U S A (2012) 1.06
Structure, function, and mechanism of the nickel metalloenzymes, CO dehydrogenase, and acetyl-CoA synthase. Chem Rev (2014) 1.06
Electrochemical kinetic investigations of the reactions of [FeFe]-hydrogenases with carbon monoxide and oxygen: comparing the importance of gas tunnels and active-site electronic/redox effects. J Am Chem Soc (2009) 1.05
Inherent protein structural flexibility at the RNA-binding interface of L30e. J Mol Biol (2003) 1.05
Three clusters of conformational states in p450cam reveal a multistep pathway for closing of the substrate access channel. Biochemistry (2011) 1.05
Structural analysis of mammalian cytochrome P450 2B4 covalently bound to the mechanism-based inactivator tert-butylphenylacetylene: insight into partial enzymatic activity. Biochemistry (2011) 1.05
Conformational states of cytochrome P450cam revealed by trapping of synthetic molecular wires. J Mol Biol (2004) 1.04
The discovery of fused pyrrole carboxylic acids as novel, potent D-amino acid oxidase (DAO) inhibitors. Bioorg Med Chem Lett (2008) 1.03
Importance of the protein framework for catalytic activity of [FeFe]-hydrogenases. J Biol Chem (2011) 1.03
Direct assessment of the reduction potential of the [4Fe-4S](1+/0) couple of the Fe protein from Azotobacter vinelandii. J Am Chem Soc (2002) 1.03
Structural characterization of the complex between alpha-naphthoflavone and human cytochrome P450 1B1. J Biol Chem (2010) 1.03
Principles of sustained enzymatic hydrogen oxidation in the presence of oxygen--the crucial influence of high potential Fe-S clusters in the electron relay of [NiFe]-hydrogenases. J Am Chem Soc (2013) 0.99
Antifungal Azoles: Structural Insights into Undesired Tight Binding to Cholesterol-Metabolizing CYP46A1. Mol Pharmacol (2013) 0.98
EPR spectroscopic studies of the Fe-S clusters in the O2-tolerant [NiFe]-hydrogenase Hyd-1 from Escherichia coli and characterization of the unique [4Fe-3S] cluster by HYSCORE. J Am Chem Soc (2012) 0.98
Structures of cytochrome P450 2B6 bound to 4-benzylpyridine and 4-(4-nitrobenzyl)pyridine: insight into inhibitor binding and rearrangement of active site side chains. Mol Pharmacol (2011) 0.97
Mechanisms of redox-coupled proton transfer in proteins: role of the proximal proline in reactions of the [3Fe-4S] cluster in Azotobacter vinelandii ferredoxin I. Biochemistry (2003) 0.97
A random-sequential mechanism for nitrite binding and active site reduction in copper-containing nitrite reductase. J Biol Chem (2006) 0.97
Mechanistic studies of the 'blue' Cu enzyme, bilirubin oxidase, as a highly efficient electrocatalyst for the oxygen reduction reaction. Phys Chem Chem Phys (2010) 0.97
Hydrogen production under aerobic conditions by membrane-bound hydrogenases from Ralstonia species. J Am Chem Soc (2008) 0.97
Water-gas shift reaction catalyzed by redox enzymes on conducting graphite platelets. J Am Chem Soc (2009) 0.97
Structure-based engineering of internal cavities in coiled-coil peptides. Biochemistry (2005) 0.97
Crystal structures of ferredoxin variants exhibiting large changes in [Fe-S] reduction potential. Nat Struct Biol (2002) 0.96
3'-Phosphoadenosine-5'-phosphosulfate reductase in complex with thioredoxin: a structural snapshot in the catalytic cycle. Biochemistry (2007) 0.96