Glutathione dependence of caspase-8 activation at the death-inducing signaling complex.

Glutathione and apoptosis. Free Radic Res (2008) 1.48

Cyanobacterial lipopolysaccharides and human health - a review. Environ Health (2006) 1.12

Inhibition of mitochondrial respiration by endogenous nitric oxide: a critical step in Fas signaling. Proc Natl Acad Sci U S A (2002) 1.07

Reactive nitrogen species-induced cell death requires Fas-dependent activation of c-Jun N-terminal kinase. Mol Cell Biol (2004) 0.99

Glutathione efflux and cell death. Antioxid Redox Signal (2012) 0.98

Acidic sphingomyelinase downregulates the liver-specific methionine adenosyltransferase 1A, contributing to tumor necrosis factor-induced lethal hepatitis. J Clin Invest (2004) 0.98

Reduced glutathione: a radioprotector or a modulator of DNA-repair activity? Nutrients (2013) 0.85

GSH-dependent regulation of Fas-mediated caspase-8 activation by acrolein. FEBS Lett (2007) 0.83

Gallic acid induces necroptosis via TNF-α signaling pathway in activated hepatic stellate cells. PLoS One (2015) 0.79

Glutathione depletion regulates both extrinsic and intrinsic apoptotic signaling cascades independent from multidrug resistance protein 1. Apoptosis (2014) 0.78

Death and anti-death: tumour resistance to apoptosis. Nat Rev Cancer (2002) 5.87

Dynamic visualization of thrombopoiesis within bone marrow. Science (2007) 4.35

Manipulation of host hepatocytes by the malaria parasite for delivery into liver sinusoids. Science (2006) 4.20

Death receptors in chemotherapy and cancer. Oncogene (2004) 2.64

Reduced suppressive effect of CD4+CD25high regulatory T cells on the T cell immune response against myelin oligodendrocyte glycoprotein in patients with multiple sclerosis. Eur J Immunol (2005) 2.28

Death receptor signaling. J Cell Sci (2005) 2.21

Pharmacologic cholinesterase inhibition improves survival in experimental sepsis. Crit Care Med (2008) 2.18

Caspases: pharmacological manipulation of cell death. J Clin Invest (2005) 2.10

Immune escape of tumors: apoptosis resistance and tumor counterattack. J Leukoc Biol (2002) 2.04

Neutralization of CD95 ligand promotes regeneration and functional recovery after spinal cord injury. Nat Med (2004) 1.95

c-FLIPR, a new regulator of death receptor-induced apoptosis. J Biol Chem (2005) 1.93

The c-FLIP-NH2 terminus (p22-FLIP) induces NF-kappaB activation. J Exp Med (2006) 1.91

TAp63alpha induces apoptosis by activating signaling via death receptors and mitochondria. EMBO J (2005) 1.90

TAp63 and DeltaNp63 in cancer and epidermal development. Cell Cycle (2007) 1.84

Accumulation of apoptotic cells in the epidermis of patients with cutaneous lupus erythematosus after ultraviolet irradiation. Arthritis Rheum (2006) 1.83

Cyclooxygenase-2 inhibition induces apoptosis signaling via death receptors and mitochondria in hepatocellular carcinoma. Cancer Res (2006) 1.82

The natural anticancer compounds rocaglamides inhibit the Raf-MEK-ERK pathway by targeting prohibitin 1 and 2. Chem Biol (2012) 1.82

The lectin-like domain of tumor necrosis factor improves lung function after rat lung transplantation--potential role for a reduction in reactive oxygen species generation. Crit Care Med (2010) 1.78

Hepatocyte-specific deletion of the antiapoptotic protein myeloid cell leukemia-1 triggers proliferation and hepatocarcinogenesis in mice. Hepatology (2010) 1.75

Prevalence of newly generated naive regulatory T cells (Treg) is critical for Treg suppressive function and determines Treg dysfunction in multiple sclerosis. J Immunol (2007) 1.74

Dirofilaria repens infection and concomitant meningoencephalitis. Emerg Infect Dis (2009) 1.60

In contrast to effector T cells, CD4+CD25+FoxP3+ regulatory T cells are highly susceptible to CD95 ligand- but not to TCR-mediated cell death. J Immunol (2005) 1.58

Dynamics within the CD95 death-inducing signaling complex decide life and death of cells. Mol Syst Biol (2010) 1.57

Stoichiometry of the CD95 death-inducing signaling complex: experimental and modeling evidence for a death effector domain chain model. Mol Cell (2012) 1.57

A novel tumor necrosis factor-mediated mechanism of direct epithelial sodium channel activation. Am J Respir Crit Care Med (2014) 1.55

Analysis of CD95 threshold signaling: triggering of CD95 (FAS/APO-1) at low concentrations primarily results in survival signaling. J Biol Chem (2007) 1.55

Suramin inhibits death receptor-induced apoptosis in vitro and fulminant apoptotic liver damage in mice. Nat Med (2004) 1.54

Development of interleukin-17-producing γδ T cells is restricted to a functional embryonic wave. Immunity (2012) 1.52

Upregulation of Bcl-2 is involved in the mediation of chemotherapy resistance in human small cell lung cancer cell lines. Int J Cancer (2002) 1.46

The traditional Chinese herbal compound rocaglamide preferentially induces apoptosis in leukemia cells by modulation of mitogen-activated protein kinase activities. Int J Cancer (2007) 1.45

Pillars article: T cell-derived B cell differentiation factor(s). Effect on the isotype switch of murine B cells. J. Exp. Med. 1982. 155: 734-748. J Immunol (2013) 1.43

p73 induces apoptosis by different mechanisms. Biochem Biophys Res Commun (2005) 1.42

Glucocorticoid cotreatment induces apoptosis resistance toward cancer therapy in carcinomas. Cancer Res (2003) 1.42

One, two, three--p53, p63, p73 and chemosensitivity. Drug Resist Updat (2007) 1.41

IκBζ is a transcriptional key regulator of CCL2/MCP-1. J Immunol (2013) 1.41

The role of CD95 in the regulation of peripheral T-cell apoptosis. Immunol Rev (2003) 1.41

Molecular mechanisms of treg-mediated T cell suppression. Front Immunol (2012) 1.41

Artesunate induces ROS-mediated apoptosis in doxorubicin-resistant T leukemia cells. PLoS One (2007) 1.40

The liver stage of Plasmodium berghei inhibits host cell apoptosis. Mol Microbiol (2005) 1.40

c-Myc mediates pre-TCR-induced proliferation but not developmental progression. Blood (2006) 1.39

Suppression of Mcl-1 via RNA interference sensitizes human hepatocellular carcinoma cells towards apoptosis induction. BMC Cancer (2006) 1.35

Concepts of activated T cell death. Crit Rev Oncol Hematol (2008) 1.33

Mitochondrial reactive oxygen species control T cell activation by regulating IL-2 and IL-4 expression: mechanism of ciprofloxacin-mediated immunosuppression. J Immunol (2010) 1.33

Regulation of IL4 gene expression by T cells and therapeutic perspectives. Nat Rev Immunol (2003) 1.32

IFN-gamma represses IL-4 expression via IRF-1 and IRF-2. Immunity (2002) 1.32

Knockout of myeloid cell leukemia-1 induces liver damage and increases apoptosis susceptibility of murine hepatocytes. Hepatology (2009) 1.31

T cell receptor-instructed alphabeta versus gammadelta lineage commitment revealed by single-cell analysis. J Exp Med (2008) 1.30

Model-based dissection of CD95 signaling dynamics reveals both a pro- and antiapoptotic role of c-FLIPL. J Cell Biol (2010) 1.30

Differential synergy of Notch and T cell receptor signaling determines alphabeta versus gammadelta lineage fate. J Exp Med (2006) 1.29

Mutant p53 gain of function: repression of CD95(Fas/APO-1) gene expression by tumor-associated p53 mutants. Oncogene (2003) 1.28

High-throughput mutation profiling of CTCL samples reveals KRAS and NRAS mutations sensitizing tumors toward inhibition of the RAS/RAF/MEK signaling cascade. Blood (2011) 1.28

Hepatocyte growth factor induces Mcl-1 in primary human hepatocytes and inhibits CD95-mediated apoptosis via Akt. Hepatology (2004) 1.28

Apoptosis in cancer--implications for therapy. Semin Oncol (2004) 1.27

Rocaglamide derivatives are immunosuppressive phytochemicals that target NF-AT activity in T cells. J Immunol (2005) 1.26

Noxa/Bcl-2 protein interactions contribute to bortezomib resistance in human lymphoid cells. J Biol Chem (2011) 1.24

Upregulation of major histocompatibility complex class I on liver cells by hepatitis C virus core protein via p53 and TAP1 impairs natural killer cell cytotoxicity. J Virol (2003) 1.23

Mcl-1 is an anti-apoptotic factor for human hepatocellular carcinoma. Int J Oncol (2006) 1.20

Rapid suppression of cytokine transcription in human CD4+CD25 T cells by CD4+Foxp3+ regulatory T cells: independence of IL-2 consumption, TGF-beta, and various inhibitors of TCR signaling. J Immunol (2007) 1.20

Wogonin preferentially kills malignant lymphocytes and suppresses T-cell tumor growth by inducing PLCgamma1- and Ca2+-dependent apoptosis. Blood (2007) 1.20

How T lymphocytes switch between life and death. Eur J Immunol (2006) 1.20

Snail regulates cell survival and inhibits cellular senescence in human metastatic prostate cancer cell lines. Cell Biol Toxicol (2010) 1.19

T cell activation is driven by an ADP-dependent glucokinase linking enhanced glycolysis with mitochondrial reactive oxygen species generation. Cell Rep (2012) 1.16

Enforced expression of miR-125b affects myelopoiesis by targeting multiple signaling pathways. Blood (2011) 1.16

Novel role for mitochondria: protein kinase Ctheta-dependent oxidative signaling organelles in activation-induced T-cell death. Mol Cell Biol (2007) 1.14

Tumor necrosis factor-alpha and angiostatin are mediators of endothelial cytotoxicity in bronchoalveolar lavages of patients with acute respiratory distress syndrome. Am J Respir Crit Care Med (2002) 1.14

Peripheral infusion of rat bone marrow derived endothelial progenitor cells leads to homing in acute lung injury. Respir Res (2007) 1.14

Glenoid version and rotator cuff tears. J Orthop Res (2004) 1.12

Dichotomal role of TNF in experimental pulmonary edema reabsorption. J Immunol (2005) 1.12

Primary human hepatocytes--a valuable tool for investigation of apoptosis and hepatitis B virus infection. J Hepatol (2003) 1.11

HTLV-1 Tax protects against CD95-mediated apoptosis by induction of the cellular FLICE-inhibitory protein (c-FLIP). Blood (2006) 1.10

CD4(+)CD25 (+) regulatory T cells in human lupus erythematosus. Arch Dermatol Res (2008) 1.10

Lack of tumor necrosis factor-related apoptosis-inducing ligand but presence of its receptors in the human brain. J Neurosci (2002) 1.09

Wogonin sensitizes resistant malignant cells to TNFalpha- and TRAIL-induced apoptosis. Blood (2006) 1.09

Function and regulation of the CD95 (APO-1/Fas) ligand in the immune system. Semin Immunol (2003) 1.09

Caspase-2 is activated at the CD95 death-inducing signaling complex in the course of CD95-induced apoptosis. Blood (2006) 1.08

Critical role for miR-181a/b-1 in agonist selection of invariant natural killer T cells. Proc Natl Acad Sci U S A (2013) 1.07

Clinical and mechanistic aspects of glucocorticoid-induced chemotherapy resistance in the majority of solid tumors. Cancer Biol Ther (2007) 1.07

Loss of caspase-9 reveals its essential role for caspase-2 activation and mitochondrial membrane depolarization. Mol Biol Cell (2006) 1.07

Src homology 2 domain-containing leukocyte phosphoprotein of 76 kDa and phospholipase C gamma 1 are required for NF-kappa B activation and lipid raft recruitment of protein kinase C theta induced by T cell costimulation. J Immunol (2003) 1.06

HIV-1 trans-activator of transcription substitutes for oxidative signaling in activation-induced T cell death. J Immunol (2005) 1.06

Regulation of T cell apoptosis during the immune response. Curr Mol Med (2002) 1.06

Inhibition of constitutively activated nuclear factor-kappaB induces reactive oxygen species- and iron-dependent cell death in cutaneous T-cell lymphoma. Cancer Res (2009) 1.06

Death receptor signaling and its function in the immune system. Curr Dir Autoimmun (2006) 1.05

Chemotherapy-induced apoptosis in hepatocellular carcinoma involves the p53 family and is mediated via the extrinsic and the intrinsic pathway. Int J Cancer (2010) 1.05

Caspase-cleaved HPK1 induces CD95L-independent activation-induced cell death in T and B lymphocytes. Blood (2007) 1.05

The lectin-like domain of TNF protects from listeriolysin-induced hyperpermeability in human pulmonary microvascular endothelial cells - a crucial role for protein kinase C-alpha inhibition. Vascul Pharmacol (2010) 1.04

Peptide-induced negative selection of thymocytes activates transcription of an NF-kappa B inhibitor. Mol Cell (2002) 1.04

A PP4 holoenzyme balances physiological and oncogenic nuclear factor-kappa B signaling in T lymphocytes. Immunity (2012) 1.03

Discontinued postnatal thymocyte development in sphingosine 1-phosphate-lyase-deficient mice. J Immunol (2009) 1.02

Phosphorylation of CARMA1 by HPK1 is critical for NF-kappaB activation in T cells. Proc Natl Acad Sci U S A (2009) 1.02

Immunoproteomic identification and serological responses to novel Chlamydia pneumoniae antigens that are associated with persistent C. pneumoniae infections. J Immunol (2008) 1.01

Calcium/calmodulin-dependent protein kinase II regulation of c-FLIP expression and phosphorylation in modulation of Fas-mediated signaling in malignant glioma cells. J Biol Chem (2002) 1.01

Multiple extrathymic precursors contribute to T-cell development with different kinetics. Blood (2009) 1.00

International validation of novel pyrogen tests based on human monocytoid cells. J Immunol Methods (2005) 0.99

Activation or suppression of NFkappaB by HPK1 determines sensitivity to activation-induced cell death. EMBO J (2005) 0.99

Atrial natriuretic peptide, a regulator of nuclear factor-kappaB activation in vivo. Endocrinology (2006) 0.99

Glucocorticoids inhibit activation-induced cell death (AICD) via direct DNA-dependent repression of the CD95 ligand gene by a glucocorticoid receptor dimer. Blood (2005) 0.99