Published in J Biol Chem on December 19, 2001
Ibrutinib and novel BTK inhibitors in clinical development. J Hematol Oncol (2013) 1.92
Conformation of full-length Bruton tyrosine kinase (Btk) from synchrotron X-ray solution scattering. EMBO J (2003) 1.13
Structure-based reassessment of the caveolin signaling model: do caveolae regulate signaling through caveolin-protein interactions? Dev Cell (2012) 1.04
Caveolin-1 orchestrates TCR synaptic polarity, signal specificity, and function in CD8 T cells. J Immunol (2011) 0.98
STAT3 activation in pressure-overloaded feline myocardium: role for integrins and the tyrosine kinase BMX. Int J Biol Sci (2008) 0.96
Loss of Bmx nonreceptor tyrosine kinase prevents pressure overload-induced cardiac hypertrophy. Circ Res (2008) 0.91
Evaluating caveolin interactions: do proteins interact with the caveolin scaffolding domain through a widespread aromatic residue-rich motif? PLoS One (2012) 0.90
Defective Toll-like receptor 9-mediated cytokine production in B cells from Bruton's tyrosine kinase-deficient mice. Immunology (2007) 0.89
Dual phosphorylation of Btk by Akt/protein kinase b provides docking for 14-3-3ζ, regulates shuttling, and attenuates both tonic and induced signaling in B cells. Mol Cell Biol (2013) 0.83
Caveolin-1 suppresses human immunodeficiency virus-1 replication by inhibiting acetylation of NF-κB. Virology (2012) 0.83
Both internalization and AIP1 association are required for tumor necrosis factor receptor 2-mediated JNK signaling. Arterioscler Thromb Vasc Biol (2012) 0.82
Caveolin-1-dependent nanoscale organization of the BCR regulates B cell tolerance. Nat Immunol (2017) 0.79
Role of caveolin-1 and caveolae signaling in endotoxemia and sepsis. Life Sci (2013) 0.78
Role of Bruton's tyrosine kinase inhibitors in HIV-1-infected cells. J Neurovirol (2015) 0.75
Bruton's tyrosine kinase (Btk): function, regulation, and transformation with special emphasis on the PH domain. Immunol Rev (2009) 2.30
Bruton's tyrosine kinase: cell biology, sequence conservation, mutation spectrum, siRNA modifications, and expression profiling. Immunol Rev (2005) 1.56
BTKbase: the mutation database for X-linked agammaglobulinemia. Hum Mutat (2006) 1.55
The transcriptional regulator PLZF induces the development of CD44 high memory phenotype T cells. Proc Natl Acad Sci U S A (2008) 1.54
Expression analysis in multiple muscle groups and serum reveals complexity in the microRNA transcriptome of the mdx mouse with implications for therapy. Mol Ther Nucleic Acids (2012) 1.53
The subcellular Sox11 distribution pattern identifies subsets of mantle cell lymphoma: correlation to overall survival. Br J Haematol (2008) 1.47
Design of a peptide-based vector, PepFect6, for efficient delivery of siRNA in cell culture and systemically in vivo. Nucleic Acids Res (2011) 1.35
Dual functions of Bruton's tyrosine kinase and Tec kinase during Fcgamma receptor-induced signaling and phagocytosis. J Immunol (2008) 1.15
Conformation of full-length Bruton tyrosine kinase (Btk) from synchrotron X-ray solution scattering. EMBO J (2003) 1.13
Proteasome-dependent autoregulation of Bruton tyrosine kinase (Btk) promoter via NF-kappaB. Blood (2008) 1.08
Biological activity and biotechnological aspects of peptide nucleic acid. Adv Genet (2006) 1.07
Delivery of nucleic acids with a stearylated (RxR)4 peptide using a non-covalent co-incubation strategy. J Control Release (2009) 1.01
Choosing CCR5 or Rev siRNA in HIV-1. Nat Biotechnol (2003) 1.00
Genetic and demographic features of X-linked agammaglobulinemia in Eastern and Central Europe: a cohort study. Mol Immunol (2009) 0.97
PepFect 14, a novel cell-penetrating peptide for oligonucleotide delivery in solution and as solid formulation. Nucleic Acids Res (2011) 0.97
TEC family kinases in health and disease--loss-of-function of BTK and ITK and the gain-of-function fusions ITK-SYK and BTK-SYK. FEBS J (2011) 0.97
A peptide-based vector for efficient gene transfer in vitro and in vivo. Mol Ther (2011) 0.95
Expression profiling in transformed human B cells: influence of Btk mutations and comparison to B cell lymphomas using filter and oligonucleotide arrays. Eur J Immunol (2002) 0.94
Differential expression and molecular characterisation of Lmo7, Myo1e, Sash1, and Mcoln2 genes in Btk-defective B-cells. Cell Immunol (2005) 0.94
Biological activity and biotechnological aspects of locked nucleic acids. Adv Genet (2013) 0.93
Non-viral nanovectors for gene delivery: factors that govern successful therapeutics. Expert Opin Drug Deliv (2010) 0.91
Gene transfer to mouse heart and skeletal muscles using a minicircle expressing human vascular endothelial growth factor. J Cardiovasc Pharmacol (2009) 0.91
Zorro locked nucleic acid induces sequence-specific gene silencing. FASEB J (2007) 0.90
Identification of phosphorylation sites within the SH3 domains of Tec family tyrosine kinases. Biochim Biophys Acta (2003) 0.89
Defective Toll-like receptor 9-mediated cytokine production in B cells from Bruton's tyrosine kinase-deficient mice. Immunology (2007) 0.89
Silencing of Bruton's tyrosine kinase (Btk) using short interfering RNA duplexes (siRNA). FEBS Lett (2002) 0.89
Contiguous X-chromosome deletion syndrome encompassing the BTK, TIMM8A, TAF7L, and DRP2 genes. J Clin Immunol (2007) 0.87
Stromal-derived factor-1 abolishes constitutive apoptosis of WHIM syndrome neutrophils harbouring a truncating CXCR4 mutation. Br J Haematol (2006) 0.87
Btk29A promotes Wnt4 signaling in the niche to terminate germ cell proliferation in Drosophila. Science (2014) 0.86
Ischemia-reperfusion injury and pregnancy initiate time-dependent and robust signs of up-regulation of cardiac progenitor cells. PLoS One (2012) 0.86
Regulation of Bruton tyrosine kinase by the peptidylprolyl isomerase Pin1. J Biol Chem (2006) 0.86
Compensatory signals associated with the activation of human GC 5' splice sites. Nucleic Acids Res (2011) 0.85
Clinical and genetic diagnosis of warts, hypogammaglobulinemia, infections, and myelokathexis syndrome in 10 patients. J Allergy Clin Immunol (2009) 0.85
Development of bis-locked nucleic acid (bisLNA) oligonucleotides for efficient invasion of supercoiled duplex DNA. Nucleic Acids Res (2013) 0.85
Phylogeny of Tec family kinases identification of a premetazoan origin of Btk, Bmx, Itk, Tec, Txk, and the Btk regulator SH3BP5. Adv Genet (2008) 0.85
Gene expression profile of B cells from Xid mice and Btk knockout mice. Eur J Immunol (2004) 0.84
Functional replacement of Drosophila Btk29A with human Btk in male genital development and survival. FEBS Lett (2005) 0.84
Dual phosphorylation of Btk by Akt/protein kinase b provides docking for 14-3-3ζ, regulates shuttling, and attenuates both tonic and induced signaling in B cells. Mol Cell Biol (2013) 0.83
Stable expression of short interfering RNA for DT-diaphorase induces neurotoxicity. Chem Res Toxicol (2010) 0.83
Agammaglobulinemia: causative mutations and their implications for novel therapies. Expert Rev Clin Immunol (2013) 0.83
Increased stability and specificity through combined hybridization of peptide nucleic acid (PNA) and locked nucleic acid (LNA) to supercoiled plasmids for PNA-anchored "Bioplex" formation. Biomol Eng (2005) 0.82
Regulation of nucleocytoplasmic shuttling of Bruton's tyrosine kinase (Btk) through a novel SH3-dependent interaction with ankyrin repeat domain 54 (ANKRD54). Mol Cell Biol (2012) 0.82
Signaling of the ITK (interleukin 2-inducible T cell kinase)-SYK (spleen tyrosine kinase) fusion kinase is dependent on adapter SLP-76 and on the adapter function of the kinases SYK and ZAP70. J Biol Chem (2013) 0.81
NF-kappaB regulates the transcription of protein tyrosine kinase Tec. FEBS J (2009) 0.81
Inducible H1 promoter-driven lentiviral siRNA expression by Stuffer reporter deletion. Oligonucleotides (2005) 0.81
Single-stranded DNA oligonucleotides inhibit TLR3-mediated responses in human monocyte-derived dendritic cells and in vivo in cynomolgus macaques. Blood (2012) 0.81
The gene involved in X-linked agammaglobulinaemia is a member of the Src family of protein-tyrosine kinases. 1993. J Immunol (2012) 0.80
Cooperative strand invasion of supercoiled plasmid DNA by mixed linear PNA and PNA-peptide chimeras. Biomol Eng (2004) 0.80
Solid formulation of cell-penetrating peptide nanocomplexes with siRNA and their stability in simulated gastric conditions. J Control Release (2012) 0.80
Splice-correcting oligonucleotides restore BTK function in X-linked agammaglobulinemia model. J Clin Invest (2014) 0.80
Splice-correction strategies for treatment of X-linked agammaglobulinemia. Curr Allergy Asthma Rep (2015) 0.80
Nanotechnology approaches for gene transfer. Genetica (2009) 0.79
Self-assembling supramolecular complexes by single-stranded extension from plasmid DNA. Oligonucleotides (2007) 0.79
Formulation and delivery of splice-correction antisense oligonucleotides by amino acid modified polyethylenimine. Mol Pharm (2010) 0.79
Mantle cell lymphomas with low levels of cyclin D1 long mRNA transcripts are highly proliferative and can be discriminated by elevated cyclin A2 and cyclin B1. Int J Cancer (2005) 0.78
Optimizing anti-gene oligonucleotide 'Zorro-LNA' for improved strand invasion into duplex DNA. Nucleic Acids Res (2010) 0.78
A synthetic snRNA m3G-CAP enhances nuclear delivery of exogenous proteins and nucleic acids. Nucleic Acids Res (2009) 0.78
Proteasome inhibitors block HIV-1 replication by affecting both cellular and viral targets. Biochem Biophys Res Commun (2009) 0.78
Phosphatidylinositol-3-kinase-dependent phosphorylation of SLP-76 by the lymphoma-associated ITK-SYK fusion-protein. Biochem Biophys Res Commun (2009) 0.78
Distinct gene expression signature in Btk-defective T1 B-cells. Biochem Biophys Res Commun (2006) 0.78
Bioplex technology: novel synthetic gene delivery system based on peptides anchored to nucleic acids. Methods Enzymol (2002) 0.77
Design and application of bispecific splice-switching oligonucleotides. Nucleic Acid Ther (2014) 0.77
Tec family kinases. FEBS J (2011) 0.77
Sequence-specific inhibition of RNA polymerase III-dependent transcription using Zorro locked nucleic acid (LNA). J Gene Med (2008) 0.76
Cyclodextrin-peptide conjugates for sequence specific DNA binding. Org Biomol Chem (2015) 0.76
Ligands of the asialoglycoprotein receptor for targeted gene delivery, part 1: Synthesis of and binding studies with biotinylated cluster glycosides containing N-acetylgalactosamine. Glycoconj J (2004) 0.76
Longitudinal plication--a surgical strategy for complete rectal prolapse management. BMC Surg (2014) 0.75
Differential evolutionary wiring of the tyrosine kinase Btk. PLoS One (2012) 0.75
Circular RNA interference effector molecules (WO10084371). Expert Opin Ther Pat (2010) 0.75
Peptide nanoparticle delivery of charge-neutral splice-switching morpholino oligonucleotides. Nucleic Acid Ther (2015) 0.75
Temperature-assisted cyclic hybridization (TACH): an improved method for supercoiled DNA hybridization. Mol Biotechnol (2010) 0.75